FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5343, 588 aa 1>>>pF1KB5343 588 - 588 aa - 588 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.7741+/-0.00128; mu= -1.4083+/- 0.077 mean_var=255.2088+/-52.451, 0's: 0 Z-trim(109.1): 16 B-trim: 172 in 1/51 Lambda= 0.080284 statistics sampled from 10657 (10660) to 10657 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.327), width: 16 Scan time: 2.680 The best scores are: opt bits E(32554) CCDS13880.1 PES1 gene_id:23481|Hs108|chr22 ( 588) 3866 461.6 1.3e-129 CCDS58802.1 PES1 gene_id:23481|Hs108|chr22 ( 583) 3816 455.8 7e-128 CCDS74842.1 PES1 gene_id:23481|Hs108|chr22 ( 449) 2950 355.4 9e-98 >>CCDS13880.1 PES1 gene_id:23481|Hs108|chr22 (588 aa) initn: 3866 init1: 3866 opt: 3866 Z-score: 2440.6 bits: 461.6 E(32554): 1.3e-129 Smith-Waterman score: 3866; 100.0% identity (100.0% similar) in 588 aa overlap (1-588:1-588) 10 20 30 40 50 60 pF1KB5 MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIAARALRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIAARALRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PTDGEMSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGEVSWDKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PTDGEMSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGEVSWDKSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 CIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLPVAEYFSGVQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 CIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLPVAEYFSGVQLP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEEDDNNEGDGDEEGENEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEEDDNNEGDGDEEGENEEE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 EEDAEAGSEKEEEARLAALEEQRMEGKKPRVMAGTLKLEDKQRLAQEEESEAKRLAIMMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 EEDAEAGSEKEEEARLAALEEQRMEGKKPRVMAGTLKLEDKQRLAQEEESEAKRLAIMMM 490 500 510 520 530 540 550 560 570 580 pF1KB5 KKREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE :::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KKREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE 550 560 570 580 >>CCDS58802.1 PES1 gene_id:23481|Hs108|chr22 (583 aa) initn: 2264 init1: 2023 opt: 3816 Z-score: 2409.3 bits: 455.8 E(32554): 7e-128 Smith-Waterman score: 3816; 99.1% identity (99.1% similar) in 588 aa overlap (1-588:1-583) 10 20 30 40 50 60 pF1KB5 MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHII 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIAARALRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIAARALRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PTDGEMSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGEVSWDKSL ::::: :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PTDGE-----EDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGEVSWDKSL 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 CIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLPVAEYFSGVQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLPVAEYFSGVQLP 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 PHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEEDDNNEGDGDEEGENEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEEDDNNEGDGDEEGENEEE 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 EEDAEAGSEKEEEARLAALEEQRMEGKKPRVMAGTLKLEDKQRLAQEEESEAKRLAIMMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EEDAEAGSEKEEEARLAALEEQRMEGKKPRVMAGTLKLEDKQRLAQEEESEAKRLAIMMM 480 490 500 510 520 530 550 560 570 580 pF1KB5 KKREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE :::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KKREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE 540 550 560 570 580 >>CCDS74842.1 PES1 gene_id:23481|Hs108|chr22 (449 aa) initn: 2950 init1: 2950 opt: 2950 Z-score: 1868.8 bits: 355.4 E(32554): 9e-98 Smith-Waterman score: 2950; 100.0% identity (100.0% similar) in 449 aa overlap (140-588:1-449) 110 120 130 140 150 160 pF1KB5 NKPNYKLDHIIKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFM :::::::::::::::::::::::::::::: CCDS74 MCFLFSTFPRTGKCHVQTIQLCRRLTVEFM 10 20 30 170 180 190 200 210 220 pF1KB5 HYIIAARALRKVFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 HYIIAARALRKVFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTT 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB5 LLGFVNFRLYQLLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LLGFVNFRLYQLLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVP 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB5 ATEEEAEVDEFPTDGEMSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ATEEEAEVDEFPTDGEMSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRS 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB5 FGGEVSWDKSLCIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 FGGEVSWDKSLCIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLP 220 230 240 250 260 270 410 420 430 440 450 460 pF1KB5 VAEYFSGVQLPPHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEEDDNNEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 VAEYFSGVQLPPHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEEDDNNEG 280 290 300 310 320 330 470 480 490 500 510 520 pF1KB5 DGDEEGENEEEEEDAEAGSEKEEEARLAALEEQRMEGKKPRVMAGTLKLEDKQRLAQEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DGDEEGENEEEEEDAEAGSEKEEEARLAALEEQRMEGKKPRVMAGTLKLEDKQRLAQEEE 340 350 360 370 380 390 530 540 550 560 570 580 pF1KB5 SEAKRLAIMMMKKREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SEAKRLAIMMMKKREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE 400 410 420 430 440 588 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:28:54 2016 done: Thu Nov 3 22:28:55 2016 Total Scan time: 2.680 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]