FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5344, 232 aa 1>>>pF1KB5344 232 - 232 aa - 232 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0322+/-0.000826; mu= 16.2084+/- 0.051 mean_var=76.2959+/-15.514, 0's: 0 Z-trim(109.0): 162 B-trim: 642 in 2/50 Lambda= 0.146833 statistics sampled from 10425 (10602) to 10425 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.326), width: 16 Scan time: 2.200 The best scores are: opt bits E(32554) CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 1542 335.6 1.7e-92 CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 988 218.2 3.7e-57 CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 831 185.0 3.6e-47 CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 550 125.4 2.7e-29 CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 546 124.5 4.8e-29 CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 543 123.9 7.5e-29 CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 526 120.3 9.6e-28 CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 501 115.0 3.8e-26 CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 495 113.7 8.5e-26 CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 495 113.7 8.5e-26 CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 492 113.1 1.3e-25 CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 488 112.2 2.3e-25 CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 467 107.8 5.2e-24 CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 446 103.4 1.2e-22 CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 438 101.8 4.6e-22 CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 436 101.2 4.9e-22 CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 435 101.0 5.7e-22 CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 434 100.8 7.2e-22 CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 414 96.6 1.4e-20 CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 332 79.2 2.1e-15 CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 293 71.0 6.9e-13 CCDS7261.1 RHOBTB1 gene_id:9886|Hs108|chr10 ( 696) 290 70.8 2.6e-12 CCDS6034.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 727) 274 67.4 2.8e-11 CCDS55211.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 734) 274 67.4 2.8e-11 CCDS55210.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 749) 274 67.4 2.9e-11 >>CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 (232 aa) initn: 1542 init1: 1542 opt: 1542 Z-score: 1774.2 bits: 335.6 E(32554): 1.7e-92 Smith-Waterman score: 1542; 100.0% identity (100.0% similar) in 232 aa overlap (1-232:1-232) 10 20 30 40 50 60 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM 190 200 210 220 230 >>CCDS2190.1 RND3 gene_id:390|Hs108|chr2 (244 aa) initn: 970 init1: 936 opt: 988 Z-score: 1139.6 bits: 218.2 E(32554): 3.7e-57 Smith-Waterman score: 1001; 58.2% identity (83.2% similar) in 244 aa overlap (1-232:1-244) 10 20 30 40 50 pF1KB5 MKERRAPQPVVAR----------CKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENY :::::: : . .. ::.:.::: ::::::.:.:.::::.::.::::::::: CCDS21 MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 TACLETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTE :: .: . ::.::::::::::::::::::: : ::::::.:::::::::.::.::::. : CCDS21 TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 ILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAF : ..::.:..::.:::.:::::.:::.:::...:.:.::.:: .:::.:: :.: ::. CCDS21 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL 130 140 150 160 170 180 180 190 200 210 220 pF1KB5 TSEKSIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSEL--ISSTFKKEKAKS ::.:...::..:.. :.:: . ... . .::. :.::: :: ... ..:.:::: CCDS21 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS 190 200 210 220 230 240 230 pF1KB5 CSIM :..: CCDS21 CTVM >>CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 (227 aa) initn: 817 init1: 792 opt: 831 Z-score: 960.3 bits: 185.0 E(32554): 3.6e-47 Smith-Waterman score: 831; 53.4% identity (82.4% similar) in 221 aa overlap (13-232:7-227) 10 20 30 40 50 60 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR :::.:.:::..:::::.:::.::: :: .::::::::::: .: ...: CCDS11 MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRR 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV .::..:::::: :::::::: : ::::::.:::::::::.::.::::. : ..::...: CCDS11 IELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF .:.::: :.::::.:: :::.:. :...::: ..:::.:: :.: :. .::.:....: CCDS11 VLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVF 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELIS-STFKKEKAKSCSIM ..:.. :.. ... : .: .: .: . . . ..:..::::..: CCDS11 HVATVASLGRGHRQLRRTDSRRGMQRSAQLSGRPDRGNEGEIHKDRAKSCNLM 180 190 200 210 220 >>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa) initn: 554 init1: 537 opt: 550 Z-score: 639.5 bits: 125.4 E(32554): 2.7e-29 Smith-Waterman score: 550; 45.9% identity (77.9% similar) in 172 aa overlap (13-184:5-175) 10 20 30 40 50 60 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR : :::.::: :::: .: :..:: .::.:::::::::.: .:.. .. CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV :::.::::.:. :: .::: : :.:..:.::.:. :..... .:: :. .::.. . CCDS27 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF .:.: : :::.: : ::...:: :.. :.: .:...:: :.: :: :.. ... .: CCDS27 ILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKD-GVREVF 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM . :. CCDS27 EMATRAALQARRGKKKSGCLVL 180 190 >>CCDS854.1 RHOC gene_id:389|Hs108|chr1 (193 aa) initn: 550 init1: 533 opt: 546 Z-score: 635.0 bits: 124.5 E(32554): 4.8e-29 Smith-Waterman score: 546; 46.5% identity (76.2% similar) in 172 aa overlap (13-184:5-175) 10 20 30 40 50 60 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR : :::.::: :::: .: :..:: .::.::::::::: : .:.. .. CCDS85 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV :::.::::.:. :: .::: : :.:..:.::.:. :..... .:: :. .::.. . CCDS85 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF .:.: : ::: : : ::...:: :. :.: .:....: ::: :: :.: ... .: CCDS85 ILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKE-GVREVF 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM . :. CCDS85 EMATRAGLQVRKNKRRRGCPIL 180 190 >>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa) initn: 540 init1: 518 opt: 543 Z-score: 631.4 bits: 123.9 E(32554): 7.5e-29 Smith-Waterman score: 543; 44.9% identity (76.4% similar) in 178 aa overlap (13-190:5-181) 10 20 30 40 50 60 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR : :::.::: :::: .: :..:: .::.:::::::::.: .:.. .. CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV :::.::::.:. :: .::: : :.:..:.::... :..... .:: :. .::.. . CCDS16 VELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF .:.. : :::.: . ::...:: :. ..: :.: .. : ::: :: :.: ... .: CCDS16 ILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKE-GVREVF 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 RTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM .::. :.: CCDS16 ETATRAALQKRYGSQNGCINCCKVL 180 190 >>CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 (210 aa) initn: 500 init1: 500 opt: 526 Z-score: 611.6 bits: 120.3 E(32554): 9.6e-28 Smith-Waterman score: 526; 40.8% identity (72.8% similar) in 184 aa overlap (6-189:11-192) 10 20 30 40 50 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLE :: : : :.::::: ::::..:.:.: .::.:.::::: : . :. CCDS81 MTAAQAAGEEAP-PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 TEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYC .. . :.: .:::.:. :: .::: : :....:::::.. :.. :. ...: :. .: CCDS81 VKGKPVHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 PSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKS .. ....::::::: : : . .: .. :..:..: .:...:: ::: :: . . CCDS81 KKVPIIVVGCKTDLRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHD-N 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 IHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM .:..:. :. . :. CCDS81 VHAVFQEAAEVALSSRGRNFWRRITQGFCVVT 180 190 200 210 >>CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 (211 aa) initn: 481 init1: 481 opt: 501 Z-score: 582.9 bits: 115.0 E(32554): 3.8e-26 Smith-Waterman score: 501; 40.2% identity (67.7% similar) in 189 aa overlap (1-189:7-194) 10 20 30 40 50 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACL . . :: : . :.:.::: ::::..:.: .. .:: :.:.:::.::: . CCDS92 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 ETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDY . ..: :.:.::.:. :: .::: :... ::.:.:. : . :..: :: :. . CCDS92 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 CPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEK : . ..::::::::: : : .: . ::.: :: . .:. : .::: :: : CCDS92 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRE- 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM .....:: :. . :. CCDS92 NVEDVFREAAKVALSALKKAQRQKKRRLCLLL 180 190 200 210 >>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa) initn: 460 init1: 460 opt: 495 Z-score: 576.6 bits: 113.7 E(32554): 8.5e-26 Smith-Waterman score: 495; 40.0% identity (70.8% similar) in 185 aa overlap (15-197:5-185) 10 20 30 40 50 60 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR : :.::: ::: .: . . .: :.::::.::.: . .. . CCDS53 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKP 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV :.:.::::.:. :: .::: : ..:. :.::.. : . ... :: :. .::.: . CCDS53 VNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF .:.: : ::: : .:. .:...: .::.: :: :.::..:: ::: ::.: .......: CCDS53 ILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT-QRGLKTVF 120 130 140 150 160 190 200 210 220 230 pF1KB5 RTA--SMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM : ..:: : :. .. CCDS53 DEAIRAVLC---PPPVKKRKRKCLLL 170 180 190 >>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa) initn: 471 init1: 456 opt: 495 Z-score: 576.6 bits: 113.7 E(32554): 8.5e-26 Smith-Waterman score: 495; 40.3% identity (70.2% similar) in 191 aa overlap (15-203:5-191) 10 20 30 40 50 60 pF1KB5 MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR : :.::: ::: .: . . .: :.::::.::.: . .. . CCDS13 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKP 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV :.:.::::.:. :: .::: : ..:. :.::.. : . ... :: :. .:::: . CCDS13 VNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF .:.: : ::: : .:. .:...: :::.: :: :.::.. . ::: ::.: .......: CCDS13 ILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALT-QRGLKTVF 120 130 140 150 160 190 200 210 220 230 pF1KB5 RTA--SMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM : ..:: :.: :.. . :: CCDS13 DEAIRAVLC---PQPTRQQKRACSLL 170 180 190 232 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:38:37 2016 done: Fri Nov 4 03:38:37 2016 Total Scan time: 2.200 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]