FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5353, 391 aa 1>>>pF1KB5353 391 - 391 aa - 391 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7897+/-0.000933; mu= 12.2147+/- 0.057 mean_var=146.6647+/-28.481, 0's: 0 Z-trim(110.5): 30 B-trim: 0 in 0/52 Lambda= 0.105904 statistics sampled from 11628 (11654) to 11628 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.358), width: 16 Scan time: 3.030 The best scores are: opt bits E(32554) CCDS9013.1 NAP1L1 gene_id:4673|Hs108|chr12 ( 391) 2624 412.4 3.6e-115 CCDS76581.1 NAP1L1 gene_id:4673|Hs108|chr12 ( 383) 2417 380.8 1.2e-105 CCDS81715.1 NAP1L1 gene_id:4673|Hs108|chr12 ( 328) 2200 347.5 1e-95 CCDS41599.1 NAP1L4 gene_id:4676|Hs108|chr11 ( 375) 1635 261.3 1.1e-69 CCDS14423.1 NAP1L2 gene_id:4674|Hs108|chrX ( 460) 795 133.0 5.3e-31 CCDS14465.1 NAP1L3 gene_id:4675|Hs108|chrX ( 506) 706 119.5 7.1e-27 >>CCDS9013.1 NAP1L1 gene_id:4673|Hs108|chr12 (391 aa) initn: 2624 init1: 2624 opt: 2624 Z-score: 2181.2 bits: 412.4 E(32554): 3.6e-115 Smith-Waterman score: 2624; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391) 10 20 30 40 50 60 pF1KB5 MADIDNKEQSELDQDLDDVEEVEEEETGEETKLKARQLTVQMMQNPQILAALQERLDGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 MADIDNKEQSELDQDLDDVEEVEEEETGEETKLKARQLTVQMMQNPQILAALQERLDGLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 ETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 INAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 INAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 LSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 DSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 FAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEE 310 320 330 340 350 360 370 380 390 pF1KB5 ADEEGEEEGDEENDPDYDPKKDQNPAECKQQ ::::::::::::::::::::::::::::::: CCDS90 ADEEGEEEGDEENDPDYDPKKDQNPAECKQQ 370 380 390 >>CCDS76581.1 NAP1L1 gene_id:4673|Hs108|chr12 (383 aa) initn: 2417 init1: 2417 opt: 2417 Z-score: 2010.4 bits: 380.8 E(32554): 1.2e-105 Smith-Waterman score: 2417; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363) 10 20 30 40 50 60 pF1KB5 MADIDNKEQSELDQDLDDVEEVEEEETGEETKLKARQLTVQMMQNPQILAALQERLDGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MADIDNKEQSELDQDLDDVEEVEEEETGEETKLKARQLTVQMMQNPQILAALQERLDGLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 ETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 INAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 INAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 LSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 DSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 FAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEE 310 320 330 340 350 360 370 380 390 pF1KB5 ADEEGEEEGDEENDPDYDPKKDQNPAECKQQ ::: CCDS76 ADEGYQLFEEVKSCSKLFQRWLQ 370 380 >>CCDS81715.1 NAP1L1 gene_id:4673|Hs108|chr12 (328 aa) initn: 2200 init1: 2200 opt: 2200 Z-score: 1832.0 bits: 347.5 E(32554): 1e-95 Smith-Waterman score: 2200; 99.4% identity (100.0% similar) in 325 aa overlap (67-391:4-328) 40 50 60 70 80 90 pF1KB5 QLTVQMMQNPQILAALQERLDGLVETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFY :..::::::::::::::::::::::::::: CCDS81 MADIDNLPRVVKRRVNALKNLQVKCAQIEAKFY 10 20 30 100 110 120 130 140 150 pF1KB5 EEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEK 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 KDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 KDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEF 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 HFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 HFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKK 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB5 QKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIP 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB5 RSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ 280 290 300 310 320 >>CCDS41599.1 NAP1L4 gene_id:4676|Hs108|chr11 (375 aa) initn: 1730 init1: 865 opt: 1635 Z-score: 1364.8 bits: 261.3 E(32554): 1.1e-69 Smith-Waterman score: 1635; 64.6% identity (86.6% similar) in 373 aa overlap (13-380:3-374) 10 20 30 40 50 60 pF1KB5 MADIDNKEQSELDQDLDDVEEVEEEETGEETKLKARQLTVQMMQNPQILAALQERLDGLV :....: . :...... ....:: :.::::..:::::::::.. CCDS41 MADHSFSDGVPSDSVEAAKNAS-NTEKLTDQVMQNPRVLAALQERLDNVP 10 20 30 40 70 80 90 100 110 120 pF1KB5 ETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEI .::..:::.::..::::.::::.:::.::.:::::::::::::::::.::::::::: :. CCDS41 HTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREF 50 60 70 80 90 100 130 140 150 160 170 pF1KB5 INAIYEPTEEECEWKPD--EEDEISEELKEKAKI-EDEKKDEEKEDPKGIPEFWLTVFKN :.. :::. : ::. . ::.... ..: :. . : :. :::::::::.:.:.: CCDS41 ITGDVEPTDAESEWHSENEEEEKLAGDMKSKVVVTEKAAATAEEPDPKGIPEFWFTIFRN 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 VDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRS ::.::..:::.::::::::.:::::::: :::::::::::::::.:::: ::::::.:.: CCDS41 VDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNSVLTKTYKMKS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 EPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSF ::: .:::::.::::. : :: ::::::::::.:::::::::::::::::.:: : :.:: CCDS41 EPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESF 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 FNFFAPPEVPESGD-LDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDD-DYD :::: : .. .:. ::.:.: ::.:::::::.::::.::.:::::::::::::. . CCDS41 FNFFNPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEG 290 300 310 320 330 340 360 370 380 390 pF1KB5 EEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ ::::: . ::.:::..:.: . .:: CCDS41 EEGEEEELEGDEEGEDEDDAEINPKV 350 360 370 >>CCDS14423.1 NAP1L2 gene_id:4674|Hs108|chrX (460 aa) initn: 1082 init1: 656 opt: 795 Z-score: 670.0 bits: 133.0 E(32554): 5.3e-31 Smith-Waterman score: 1023; 47.1% identity (67.6% similar) in 380 aa overlap (23-361:57-427) 10 20 30 40 50 pF1KB5 MADIDNKEQSELDQDLDDVEEVEEEETGEETKLKARQLTVQMMQNPQILAAL :: :.::.: . . . .. . : CCDS14 LGEHLERGEDAAAGLGDDGKCGEEAAAGLGEEGENGEDTAAGSGEDGKKGGDTDEDSEA- 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB5 QERLDGLVE--TPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLY .: ::. : ..:::: :: :: :::.::.. :..:.:: .: ::.:::.: .: CCDS14 -DRPKGLIGYVLDTDFVESLPVKVKYRVLALKKLQTRAANLESKFLREFHDIERKFAEMY 90 100 110 120 130 140 120 130 140 150 pF1KB5 QPLFDKRFEIINAIYEPTEEECEWKPDEEDEISEEL-------KEKAKI----------- :::..:: .::::::::::::::.: : :: .::. .:.. . CCDS14 QPLLEKRRQIINAIYEPTEEECEYKSDSEDCDDEEMCHEEMYGNEEGMVHEYVDEDDGYE 150 160 170 180 190 200 160 170 180 190 pF1KB5 ------------EDEKKDE---------EKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEP :.:..:. :.:::::::.:::::.:::: :. .....::: CCDS14 DYYYDYAVEEEEEEEEEDDIEATGEENKEEEDPKGIPDFWLTVLKNVDTLTPLIKKYDEP 210 220 230 240 250 260 200 210 220 230 240 250 pF1KB5 ILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPE ::: : :::::.:: :.:.::.:::::.::::: ::.::::: ..:. :: . : CCDS14 ILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLAYYDPHPYRGTA 270 280 290 300 310 320 260 270 280 290 300 310 pF1KB5 IMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGD : :::.:::..:::::::::::::::. ::.::::. .:::::::.: . .: CCDS14 IEYSTGCEIDWNEGKNVTLKTIKKKQKHRIWGTIRTVTEDFPKDSFFNFFSPHGITSNGR 330 340 350 360 370 380 320 330 340 350 360 370 pF1KB5 LDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDE .: :: .:: :: :::::::.:.:.:.:.... .: ..: CCDS14 DGND-------DFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDAIYDKIIYDNW 390 400 410 420 430 380 390 pF1KB5 ENDPDYDPKKDQNPAECKQQ CCDS14 MAAIEEVKACCKNLEALVEDIDR 440 450 460 >>CCDS14465.1 NAP1L3 gene_id:4675|Hs108|chrX (506 aa) initn: 984 init1: 505 opt: 706 Z-score: 596.0 bits: 119.5 E(32554): 7.1e-27 Smith-Waterman score: 751; 37.4% identity (53.8% similar) in 377 aa overlap (83-345:113-487) 60 70 80 90 100 110 pF1KB5 QERLDGLVETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQP :.: .: .... : . .:::::::: : .: CCDS14 PSRRARRAPLGTNFVDRLPQAVRNRVQALRNIQDECDKVDTLFLKAIHDLERKYAELNKP 90 100 110 120 130 140 120 130 140 pF1KB5 LFDKRFEIINAIYEPTEEECEWK------------------------------PDEEDEI :.:.::.:::: ::::::::::. : :. :. CCDS14 LYDRRFQIINAEYEPTEEECEWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEENPKENPEV 150 160 170 180 190 200 150 160 pF1KB5 SEELKEKAKIEDEKKDEEKE---------------------------------------- . : :: : : :::::: CCDS14 KAEEKEVPKEIPEVKDEEKEVPKEIPEVKAEEKADSKDCMEATPEVKEDPKEVPQVKADD 210 220 230 240 250 260 170 pF1KB5 --------------------------------------------DPKGIPEFWLTVFKNV ::::::..:: :.::: CCDS14 KEQPKATEAKARAAVRETHKRVPEERLQDSVDLKRARKGKPKREDPKGIPDYWLIVLKNV 270 280 290 300 310 320 180 190 200 210 220 230 pF1KB5 DLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSE : :. :.:..:::::: :.:...::: :::.:...:::: :: :: ::::.::: .... CCDS14 DKLGPMIQKYDEPILKFLSDVSLKFSKPGQPVSYTFEFHFLPNPYFRNEVLVKTYIIKAK 330 340 350 360 370 380 240 250 260 270 280 290 pF1KB5 PDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFF :: .::: : :: : ::.:::..::.::. : ... . : .. ..: : ::: CCDS14 PDHNDPFFSWGWEIEDCKGCKIDWRRGKDVTVTTTQSRT--TATGEIEIQPRVVPNASFF 390 400 410 420 430 440 300 310 320 330 340 350 pF1KB5 NFFAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEG :::.:::.: : :. .::: :::::..:.. .: .:. :.::: CCDS14 NFFSPPEIPMIGKLEPREDAILDEDFEIGQILHDNVILKSIYYYTGEVNGTYYQFGKHYG 450 460 470 480 490 500 360 370 380 390 pF1KB5 EEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ CCDS14 NKKYRK 391 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:29:29 2016 done: Thu Nov 3 22:29:29 2016 Total Scan time: 3.030 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]