FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5359, 183 aa 1>>>pF1KB5359 183 - 183 aa - 183 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0468+/-0.000311; mu= 9.9300+/- 0.020 mean_var=95.4865+/-18.700, 0's: 0 Z-trim(117.6): 41 B-trim: 67 in 1/49 Lambda= 0.131251 statistics sampled from 29623 (29669) to 29623 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.348), width: 16 Scan time: 5.950 The best scores are: opt bits E(85289) NP_009207 (OMIM: 604477) chromobox protein homolog ( 183) 1221 240.7 9.6e-64 XP_005249668 (OMIM: 604477) PREDICTED: chromobox p ( 183) 1221 240.7 9.6e-64 NP_057671 (OMIM: 604477) chromobox protein homolog ( 183) 1221 240.7 9.6e-64 NP_006798 (OMIM: 604511) chromobox protein homolog ( 185) 848 170.1 1.8e-42 NP_001120700 (OMIM: 604511) chromobox protein homo ( 185) 848 170.1 1.8e-42 NP_001120793 (OMIM: 604478) chromobox protein homo ( 191) 470 98.6 6.4e-21 NP_036249 (OMIM: 604478) chromobox protein homolog ( 191) 470 98.6 6.4e-21 NP_001120794 (OMIM: 604478) chromobox protein homo ( 191) 470 98.6 6.4e-21 XP_011513299 (OMIM: 603778) PREDICTED: chromodomai ( 522) 202 48.1 2.7e-05 NP_004815 (OMIM: 603778) chromodomain Y-like prote ( 544) 202 48.1 2.8e-05 NP_005180 (OMIM: 602770,613080) chromobox protein ( 532) 199 47.5 4.1e-05 XP_011523684 (OMIM: 602770,613080) PREDICTED: chro ( 586) 199 47.6 4.4e-05 NP_059990 (OMIM: 611626) M-phase phosphoprotein 8 ( 860) 200 47.9 5.2e-05 XP_011533426 (OMIM: 611626) PREDICTED: M-phase pho ( 879) 200 47.9 5.3e-05 NP_116036 (OMIM: 602770,613080) chromobox protein ( 211) 190 45.6 6.3e-05 NP_003646 (OMIM: 603079) E3 SUMO-protein ligase CB ( 560) 194 46.6 8.1e-05 NP_001180355 (OMIM: 606503) histone-lysine N-methy ( 230) 185 44.6 0.00013 NP_001180353 (OMIM: 606503) histone-lysine N-methy ( 410) 186 45.0 0.00018 XP_006724240 (OMIM: 608457) PREDICTED: chromobox p ( 192) 181 43.8 0.00019 XP_016884168 (OMIM: 608457) PREDICTED: chromobox p ( 250) 182 44.1 0.00021 NP_783640 (OMIM: 608457) chromobox protein homolog ( 251) 182 44.1 0.00021 XP_005261470 (OMIM: 608457) PREDICTED: chromobox p ( 158) 179 43.4 0.00021 XP_011528327 (OMIM: 608457) PREDICTED: chromobox p ( 165) 174 42.5 0.00043 XP_006724241 (OMIM: 608457) PREDICTED: chromobox p ( 166) 174 42.5 0.00043 XP_006724239 (OMIM: 608457) PREDICTED: chromobox p ( 200) 174 42.5 0.0005 XP_006724238 (OMIM: 608457) PREDICTED: chromobox p ( 258) 174 42.6 0.00061 XP_006724237 (OMIM: 608457) PREDICTED: chromobox p ( 259) 174 42.6 0.00061 XP_011529814 (OMIM: 400016,415000) PREDICTED: test ( 470) 177 43.3 0.00066 NP_733841 (OMIM: 400016,415000) testis-specific ch ( 540) 177 43.4 0.00074 NP_004816 (OMIM: 400018,415000) testis-specific ch ( 541) 177 43.4 0.00074 NP_004671 (OMIM: 400016,415000) testis-specific ch ( 554) 177 43.4 0.00075 >>NP_009207 (OMIM: 604477) chromobox protein homolog 3 [ (183 aa) initn: 1221 init1: 1221 opt: 1221 Z-score: 1265.4 bits: 240.7 E(85289): 9.6e-64 Smith-Waterman score: 1221; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB5 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 WEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPED 130 140 150 160 170 180 pF1KB5 EAQ ::: NP_009 EAQ >>XP_005249668 (OMIM: 604477) PREDICTED: chromobox prote (183 aa) initn: 1221 init1: 1221 opt: 1221 Z-score: 1265.4 bits: 240.7 E(85289): 9.6e-64 Smith-Waterman score: 1221; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB5 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPED 130 140 150 160 170 180 pF1KB5 EAQ ::: XP_005 EAQ >>NP_057671 (OMIM: 604477) chromobox protein homolog 3 [ (183 aa) initn: 1221 init1: 1221 opt: 1221 Z-score: 1265.4 bits: 240.7 E(85289): 9.6e-64 Smith-Waterman score: 1221; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB5 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 WEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPED 130 140 150 160 170 180 pF1KB5 EAQ ::: NP_057 EAQ >>NP_006798 (OMIM: 604511) chromobox protein homolog 1 [ (185 aa) initn: 877 init1: 449 opt: 848 Z-score: 883.6 bits: 170.1 E(85289): 1.8e-42 Smith-Waterman score: 848; 73.6% identity (88.2% similar) in 178 aa overlap (11-181:1-178) 10 20 30 40 50 pF1KB5 MASNKTTLQKMGKKQNGKS-KKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADN :::::: :. ..: : : ::.:::::::::::.:::::.::::::.: :: NP_006 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDN 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 TWEPEENLDCPELIEAFLNSQKAGKEKD---GTKRKSLSDSES--DDSKSKKKRDAADKP :::::::::::.:: ::.:::...: : : :::. ::::. ..:: :::.. ..:: NP_006 TWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 RGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW :::::::.:::::::::::::::::::::.::::::: :::::.::::.::.:::::::: NP_006 RGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 120 130 140 150 160 170 180 pF1KB5 HSCP-EDEAQ :: : ::. NP_006 HSYPSEDDDKKDDKN 180 >>NP_001120700 (OMIM: 604511) chromobox protein homolog (185 aa) initn: 877 init1: 449 opt: 848 Z-score: 883.6 bits: 170.1 E(85289): 1.8e-42 Smith-Waterman score: 848; 73.6% identity (88.2% similar) in 178 aa overlap (11-181:1-178) 10 20 30 40 50 pF1KB5 MASNKTTLQKMGKKQNGKS-KKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADN :::::: :. ..: : : ::.:::::::::::.:::::.::::::.: :: NP_001 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDN 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 TWEPEENLDCPELIEAFLNSQKAGKEKD---GTKRKSLSDSES--DDSKSKKKRDAADKP :::::::::::.:: ::.:::...: : : :::. ::::. ..:: :::.. ..:: NP_001 TWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 RGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW :::::::.:::::::::::::::::::::.::::::: :::::.::::.::.:::::::: NP_001 RGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW 120 130 140 150 160 170 180 pF1KB5 HSCP-EDEAQ :: : ::. NP_001 HSYPSEDDDKKDDKN 180 >>NP_001120793 (OMIM: 604478) chromobox protein homolog (191 aa) initn: 449 init1: 449 opt: 470 Z-score: 496.5 bits: 98.6 E(85289): 6.4e-21 Smith-Waterman score: 746; 63.9% identity (80.0% similar) in 180 aa overlap (11-180:1-180) 10 20 30 40 50 60 pF1KB5 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT :::: . . . . ::.:::::::::::.:.:::.::::::.. :: NP_001 MGKKTKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNT 10 20 30 40 50 70 80 90 100 110 pF1KB5 WEPEENLDCPELIEAFLNSQKAGKE---------KDGTKRKSLSDSESDDSKSKKKRDAA ::::.:::::::: :... : :: ....:::: .. .:: ::::::. . NP_001 WEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSADDIKSKKKREQS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 -DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEE : ::: :::.::.::::::: :.:::::::::.::::::::::::.:::::::::::: NP_001 NDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEE 120 130 140 150 160 170 180 pF1KB5 RLTWHSCPEDEAQ :::::. ::: NP_001 RLTWHAYPEDAENKEKETAKS 180 190 >>NP_036249 (OMIM: 604478) chromobox protein homolog 5 [ (191 aa) initn: 449 init1: 449 opt: 470 Z-score: 496.5 bits: 98.6 E(85289): 6.4e-21 Smith-Waterman score: 746; 63.9% identity (80.0% similar) in 180 aa overlap (11-180:1-180) 10 20 30 40 50 60 pF1KB5 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT :::: . . . . ::.:::::::::::.:.:::.::::::.. :: NP_036 MGKKTKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNT 10 20 30 40 50 70 80 90 100 110 pF1KB5 WEPEENLDCPELIEAFLNSQKAGKE---------KDGTKRKSLSDSESDDSKSKKKRDAA ::::.:::::::: :... : :: ....:::: .. .:: ::::::. . NP_036 WEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSADDIKSKKKREQS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 -DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEE : ::: :::.::.::::::: :.:::::::::.::::::::::::.:::::::::::: NP_036 NDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEE 120 130 140 150 160 170 180 pF1KB5 RLTWHSCPEDEAQ :::::. ::: NP_036 RLTWHAYPEDAENKEKETAKS 180 190 >>NP_001120794 (OMIM: 604478) chromobox protein homolog (191 aa) initn: 449 init1: 449 opt: 470 Z-score: 496.5 bits: 98.6 E(85289): 6.4e-21 Smith-Waterman score: 746; 63.9% identity (80.0% similar) in 180 aa overlap (11-180:1-180) 10 20 30 40 50 60 pF1KB5 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNT :::: . . . . ::.:::::::::::.:.:::.::::::.. :: NP_001 MGKKTKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNT 10 20 30 40 50 70 80 90 100 110 pF1KB5 WEPEENLDCPELIEAFLNSQKAGKE---------KDGTKRKSLSDSESDDSKSKKKRDAA ::::.:::::::: :... : :: ....:::: .. .:: ::::::. . NP_001 WEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSADDIKSKKKREQS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 -DKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEE : ::: :::.::.::::::: :.:::::::::.::::::::::::.:::::::::::: NP_001 NDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEE 120 130 140 150 160 170 180 pF1KB5 RLTWHSCPEDEAQ :::::. ::: NP_001 RLTWHAYPEDAENKEKETAKS 180 190 >>XP_011513299 (OMIM: 603778) PREDICTED: chromodomain Y- (522 aa) initn: 150 init1: 124 opt: 202 Z-score: 216.1 bits: 48.1 E(85289): 2.7e-05 Smith-Waterman score: 202; 34.0% identity (70.8% similar) in 106 aa overlap (25-124:2-106) 10 20 30 40 50 pF1KB5 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVN-GKVEYFLKWKGFTDADN : : . ::...:.: . ::.::...:::. . :. XP_011 MASEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDD 10 20 30 60 70 80 90 100 110 pF1KB5 TWEPEENL-DCPELIEAFLNSQKAGKEKDGT----KRKSLSDSESDDSKSKKKRDAADKP :::::..: .: : :. : : ... :.:..: .: : ...... :.: .. . .: XP_011 TWEPEQHLVNCEEYIHDF-NRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSP 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB5 RGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW .... : : : XP_011 KALVIGKDHESKNSQLFAASQKFRKNTAPSLSSRKNMDLAKSGIKILVPKSPVKSRTAVD 100 110 120 130 140 150 >>NP_004815 (OMIM: 603778) chromodomain Y-like protein i (544 aa) initn: 150 init1: 124 opt: 202 Z-score: 215.8 bits: 48.1 E(85289): 2.8e-05 Smith-Waterman score: 202; 34.0% identity (70.8% similar) in 106 aa overlap (25-124:2-106) 10 20 30 40 50 pF1KB5 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVN-GKVEYFLKWKGFTDADN : : . ::...:.: . ::.::...:::. . :. NP_004 MASEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDD 10 20 30 60 70 80 90 100 110 pF1KB5 TWEPEENL-DCPELIEAFLNSQKAGKEKDGT----KRKSLSDSESDDSKSKKKRDAADKP :::::..: .: : :. : : ... :.:..: .: : ...... :.: .. . .: NP_004 TWEPEQHLVNCEEYIHDF-NRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSP 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB5 RGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW .... : : : NP_004 KALVIGKDHESKNSQLFAASQKFRKNTAPSLSSRKNMDLAKSGIKILVPKSPVKSRTAVD 100 110 120 130 140 150 183 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:40:33 2016 done: Fri Nov 4 03:40:34 2016 Total Scan time: 5.950 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]