FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5360, 368 aa 1>>>pF1KB5360 368 - 368 aa - 368 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0244+/-0.000988; mu= 7.0263+/- 0.058 mean_var=104.1073+/-22.492, 0's: 0 Z-trim(107.3): 121 B-trim: 334 in 1/49 Lambda= 0.125700 statistics sampled from 9372 (9517) to 9372 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.292), width: 16 Scan time: 2.670 The best scores are: opt bits E(32554) CCDS13458.1 RAE1 gene_id:8480|Hs108|chr20 ( 368) 2574 477.6 7.3e-135 CCDS31306.1 BUB3 gene_id:9184|Hs108|chr10 ( 326) 664 131.2 1.2e-30 CCDS7635.1 BUB3 gene_id:9184|Hs108|chr10 ( 328) 664 131.2 1.2e-30 >>CCDS13458.1 RAE1 gene_id:8480|Hs108|chr20 (368 aa) initn: 2574 init1: 2574 opt: 2574 Z-score: 2534.7 bits: 477.6 E(32554): 7.3e-135 Smith-Waterman score: 2574; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE 310 320 330 340 350 360 pF1KB5 ELKPRNKK :::::::: CCDS13 ELKPRNKK >>CCDS31306.1 BUB3 gene_id:9184|Hs108|chr10 (326 aa) initn: 594 init1: 211 opt: 664 Z-score: 663.6 bits: 131.2 E(32554): 1.2e-30 Smith-Waterman score: 675; 35.2% identity (68.6% similar) in 338 aa overlap (31-366:6-325) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG ...... :.:.:. ..::: : ..::... CCDS31 MTGSNEFKLNQPPEDGISSVKFSPNT--SQFLLVS 10 20 30 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :: ..:: ..: ... . : : ::: ::: : : ....... :. :: ::...: CCDS31 SWDTSVRLYDVPANSMRL-KYQ--HTGAVLD-CAFYDPTHAWSGGLDHQLKMHDLNTDQE 40 50 60 70 80 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY .. ::::.. ... :. . ..:::::.:.:.:: :. ... ::. : .: CCDS31 NLVGTHDAPIRCVEY--CPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV .:.:: : ..:..:.:. .: :: ::.: ::. : .:: :..:.:::::: CCDS31 DRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQ----GYVLSSIEGRV 150 160 170 180 190 200 250 260 270 280 290 pF1KB5 AIHYINP-PNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSF :..:..: :. : ...::::: . .: ..:: ::.:.:: .:.:.:: :::: .. CCDS31 AVEYLDPSPEVQKKKYAFKCHRLKENNI---EQIYPVNAISFHNIHNTFATGGSDGFVNI 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 WDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAA :: . .: .. :.. :...:. .: :::: . . . .:. . ::.:... CCDS31 WDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMY-EMDDTEHPE--DGIFIRQVT 270 280 290 300 310 360 pF1KB5 E-ELKPRNKK . : ::.. CCDS31 DAETKPKST 320 >>CCDS7635.1 BUB3 gene_id:9184|Hs108|chr10 (328 aa) initn: 594 init1: 211 opt: 664 Z-score: 663.6 bits: 131.2 E(32554): 1.2e-30 Smith-Waterman score: 675; 35.2% identity (68.6% similar) in 338 aa overlap (31-366:6-325) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG ...... :.:.:. ..::: : ..::... CCDS76 MTGSNEFKLNQPPEDGISSVKFSPNT--SQFLLVS 10 20 30 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :: ..:: ..: ... . : : ::: ::: : : ....... :. :: ::...: CCDS76 SWDTSVRLYDVPANSMRL-KYQ--HTGAVLD-CAFYDPTHAWSGGLDHQLKMHDLNTDQE 40 50 60 70 80 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY .. ::::.. ... :. . ..:::::.:.:.:: :. ... ::. : .: CCDS76 NLVGTHDAPIRCVEY--CPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV .:.:: : ..:..:.:. .: :: ::.: ::. : .:: :..:.:::::: CCDS76 DRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQ----GYVLSSIEGRV 150 160 170 180 190 200 250 260 270 280 290 pF1KB5 AIHYINP-PNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSF :..:..: :. : ...::::: . .: ..:: ::.:.:: .:.:.:: :::: .. CCDS76 AVEYLDPSPEVQKKKYAFKCHRLKENNI---EQIYPVNAISFHNIHNTFATGGSDGFVNI 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 WDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAA :: . .: .. :.. :...:. .: :::: . . . .:. . ::.:... CCDS76 WDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMY-EMDDTEHPE--DGIFIRQVT 270 280 290 300 310 360 pF1KB5 E-ELKPRNKK . : ::.. CCDS76 DAETKPKSPCT 320 368 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:29:56 2016 done: Sat Nov 5 12:29:57 2016 Total Scan time: 2.670 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]