FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5360, 368 aa 1>>>pF1KB5360 368 - 368 aa - 368 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2139+/-0.000408; mu= 12.1002+/- 0.025 mean_var=117.4226+/-26.972, 0's: 0 Z-trim(114.6): 180 B-trim: 2137 in 2/52 Lambda= 0.118358 statistics sampled from 24184 (24499) to 24184 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.287), width: 16 Scan time: 6.830 The best scores are: opt bits E(85289) NP_003601 (OMIM: 603343) mRNA export factor [Homo ( 368) 2574 450.9 2.2e-126 XP_005260639 (OMIM: 603343) PREDICTED: mRNA export ( 368) 2574 450.9 2.2e-126 NP_001015885 (OMIM: 603343) mRNA export factor [Ho ( 368) 2574 450.9 2.2e-126 XP_011527390 (OMIM: 603343) PREDICTED: mRNA export ( 368) 2574 450.9 2.2e-126 XP_011527391 (OMIM: 603343) PREDICTED: mRNA export ( 368) 2574 450.9 2.2e-126 XP_005260640 (OMIM: 603343) PREDICTED: mRNA export ( 406) 2574 450.9 2.3e-126 XP_016883597 (OMIM: 603343) PREDICTED: mRNA export ( 357) 2382 418.1 1.6e-116 XP_011527389 (OMIM: 603343) PREDICTED: mRNA export ( 357) 2382 418.1 1.6e-116 NP_001007794 (OMIM: 603719) mitotic checkpoint pro ( 326) 664 124.7 3e-28 NP_004716 (OMIM: 603719) mitotic checkpoint protei ( 328) 664 124.7 3e-28 NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 232 50.9 4.9e-06 NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 232 50.9 4.9e-06 XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 232 50.9 4.9e-06 NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 202 45.8 0.00018 NP_942593 (OMIM: 610767,611081) autophagy-related ( 444) 192 44.2 0.00069 XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463) 192 44.2 0.00071 XP_005246141 (OMIM: 610767,611081) PREDICTED: auto ( 480) 192 44.2 0.00073 NP_001177196 (OMIM: 610767,611081) autophagy-relat ( 491) 192 44.2 0.00074 NP_001177195 (OMIM: 610767,611081) autophagy-relat ( 523) 192 44.3 0.00078 XP_006712671 (OMIM: 610767,611081) PREDICTED: auto ( 540) 192 44.3 0.0008 NP_060444 (OMIM: 610767,611081) autophagy-related ( 588) 192 44.3 0.00085 XP_016863186 (OMIM: 609005) PREDICTED: WD repeat-c ( 982) 195 45.0 0.00087 NP_110430 (OMIM: 610767,611081) autophagy-related ( 607) 192 44.3 0.00087 XP_005246139 (OMIM: 610767,611081) PREDICTED: auto ( 624) 192 44.3 0.00089 XP_005262782 (OMIM: 609005) PREDICTED: WD repeat-c (1216) 195 45.1 0.001 NP_851782 (OMIM: 609005) WD repeat-containing prot (1283) 195 45.1 0.0011 XP_011529884 (OMIM: 609005) PREDICTED: WD repeat-c (1290) 195 45.1 0.0011 XP_016863178 (OMIM: 609005) PREDICTED: WD repeat-c (1307) 195 45.1 0.0011 XP_016863179 (OMIM: 609005) PREDICTED: WD repeat-c (1307) 195 45.1 0.0011 XP_016863175 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 195 45.1 0.0011 XP_016863176 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 195 45.1 0.0011 XP_016863177 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 195 45.1 0.0011 NP_733828 (OMIM: 609005) WD repeat-containing prot (1322) 195 45.1 0.0011 NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 184 42.7 0.0014 NP_008882 (OMIM: 601787) transcription initiation ( 800) 181 42.5 0.0039 XP_016866423 (OMIM: 215100,266500,601757,614879) P ( 199) 169 40.0 0.0058 NP_115708 (OMIM: 616850) WD repeat domain-containi ( 315) 170 40.3 0.0072 NP_001093207 (OMIM: 616850) WD repeat domain-conta ( 315) 170 40.3 0.0072 NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 169 40.2 0.0083 NP_001269467 (OMIM: 139380,613065,616973) guanine ( 240) 167 39.7 0.0084 >>NP_003601 (OMIM: 603343) mRNA export factor [Homo sapi (368 aa) initn: 2574 init1: 2574 opt: 2574 Z-score: 2390.1 bits: 450.9 E(85289): 2.2e-126 Smith-Waterman score: 2574; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE 310 320 330 340 350 360 pF1KB5 ELKPRNKK :::::::: NP_003 ELKPRNKK >>XP_005260639 (OMIM: 603343) PREDICTED: mRNA export fac (368 aa) initn: 2574 init1: 2574 opt: 2574 Z-score: 2390.1 bits: 450.9 E(85289): 2.2e-126 Smith-Waterman score: 2574; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE 310 320 330 340 350 360 pF1KB5 ELKPRNKK :::::::: XP_005 ELKPRNKK >>NP_001015885 (OMIM: 603343) mRNA export factor [Homo s (368 aa) initn: 2574 init1: 2574 opt: 2574 Z-score: 2390.1 bits: 450.9 E(85289): 2.2e-126 Smith-Waterman score: 2574; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE 310 320 330 340 350 360 pF1KB5 ELKPRNKK :::::::: NP_001 ELKPRNKK >>XP_011527390 (OMIM: 603343) PREDICTED: mRNA export fac (368 aa) initn: 2574 init1: 2574 opt: 2574 Z-score: 2390.1 bits: 450.9 E(85289): 2.2e-126 Smith-Waterman score: 2574; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE 310 320 330 340 350 360 pF1KB5 ELKPRNKK :::::::: XP_011 ELKPRNKK >>XP_011527391 (OMIM: 603343) PREDICTED: mRNA export fac (368 aa) initn: 2574 init1: 2574 opt: 2574 Z-score: 2390.1 bits: 450.9 E(85289): 2.2e-126 Smith-Waterman score: 2574; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE 310 320 330 340 350 360 pF1KB5 ELKPRNKK :::::::: XP_011 ELKPRNKK >>XP_005260640 (OMIM: 603343) PREDICTED: mRNA export fac (406 aa) initn: 2574 init1: 2574 opt: 2574 Z-score: 2389.5 bits: 450.9 E(85289): 2.3e-126 Smith-Waterman score: 2574; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:39-406) 10 20 30 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMK :::::::::::::::::::::::::::::: XP_005 PPGSALLRDAGARAGLLTKLRYWALEARFKMSLFGTTSGFGTSGTSMFGSATTDNHNPMK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 DIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 DVCWSDDGSKVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVCWSDDGSKVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWD 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 KTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB5 LKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAP 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB5 QDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIF 310 320 330 340 350 360 340 350 360 pF1KB5 AYASSYDWSKGHEFYNPQKKNYIFLRNAAEELKPRNKK :::::::::::::::::::::::::::::::::::::: XP_005 AYASSYDWSKGHEFYNPQKKNYIFLRNAAEELKPRNKK 370 380 390 400 >>XP_016883597 (OMIM: 603343) PREDICTED: mRNA export fac (357 aa) initn: 2382 init1: 2382 opt: 2382 Z-score: 2213.0 bits: 418.1 E(85289): 1.6e-116 Smith-Waterman score: 2382; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE :::::::::::::::::::::::::::::::::::::::: XP_016 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKACCCFCVSLFEGLLCEP 310 320 330 340 350 pF1KB5 ELKPRNKK >>XP_011527389 (OMIM: 603343) PREDICTED: mRNA export fac (357 aa) initn: 2382 init1: 2382 opt: 2382 Z-score: 2213.0 bits: 418.1 E(85289): 1.6e-116 Smith-Waterman score: 2382; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAE :::::::::::::::::::::::::::::::::::::::: XP_011 DKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKACCCFCVSLFEGLLCEP 310 320 330 340 350 pF1KB5 ELKPRNKK >>NP_001007794 (OMIM: 603719) mitotic checkpoint protein (326 aa) initn: 594 init1: 211 opt: 664 Z-score: 628.1 bits: 124.7 E(85289): 3e-28 Smith-Waterman score: 675; 35.2% identity (68.6% similar) in 338 aa overlap (31-366:6-325) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG ...... :.:.:. ..::: : ..::... NP_001 MTGSNEFKLNQPPEDGISSVKFSPNT--SQFLLVS 10 20 30 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :: ..:: ..: ... . : : ::: ::: : : ....... :. :: ::...: NP_001 SWDTSVRLYDVPANSMRL-KYQ--HTGAVLD-CAFYDPTHAWSGGLDHQLKMHDLNTDQE 40 50 60 70 80 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY .. ::::.. ... :. . ..:::::.:.:.:: :. ... ::. : .: NP_001 NLVGTHDAPIRCVEY--CPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV .:.:: : ..:..:.:. .: :: ::.: ::. : .:: :..:.:::::: NP_001 DRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQ----GYVLSSIEGRV 150 160 170 180 190 200 250 260 270 280 290 pF1KB5 AIHYINP-PNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSF :..:..: :. : ...::::: . .: ..:: ::.:.:: .:.:.:: :::: .. NP_001 AVEYLDPSPEVQKKKYAFKCHRLKENNI---EQIYPVNAISFHNIHNTFATGGSDGFVNI 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 WDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAA :: . .: .. :.. :...:. .: :::: . . . .:. . ::.:... NP_001 WDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMY-EMDDTEHPE--DGIFIRQVT 270 280 290 300 310 360 pF1KB5 E-ELKPRNKK . : ::.. NP_001 DAETKPKST 320 >>NP_004716 (OMIM: 603719) mitotic checkpoint protein BU (328 aa) initn: 594 init1: 211 opt: 664 Z-score: 628.1 bits: 124.7 E(85289): 3e-28 Smith-Waterman score: 675; 35.2% identity (68.6% similar) in 338 aa overlap (31-366:6-325) 10 20 30 40 50 60 pF1KB5 MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG ...... :.:.:. ..::: : ..::... NP_004 MTGSNEFKLNQPPEDGISSVKFSPNT--SQFLLVS 10 20 30 70 80 90 100 110 120 pF1KB5 SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQA :: ..:: ..: ... . : : ::: ::: : : ....... :. :: ::...: NP_004 SWDTSVRLYDVPANSMRL-KYQ--HTGAVLD-CAFYDPTHAWSGGLDHQLKMHDLNTDQE 40 50 60 70 80 130 140 150 160 170 180 pF1KB5 IQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIY .. ::::.. ... :. . ..:::::.:.:.:: :. ... ::. : .: NP_004 NLVGTHDAPIRCVEY--CPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 PMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRV .:.:: : ..:..:.:. .: :: ::.: ::. : .:: :..:.:::::: NP_004 DRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQ----GYVLSSIEGRV 150 160 170 180 190 200 250 260 270 280 290 pF1KB5 AIHYINP-PNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSF :..:..: :. : ...::::: . .: ..:: ::.:.:: .:.:.:: :::: .. NP_004 AVEYLDPSPEVQKKKYAFKCHRLKENNI---EQIYPVNAISFHNIHNTFATGGSDGFVNI 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 WDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAA :: . .: .. :.. :...:. .: :::: . . . .:. . ::.:... NP_004 WDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMY-EMDDTEHPE--DGIFIRQVT 270 280 290 300 310 360 pF1KB5 E-ELKPRNKK . : ::.. NP_004 DAETKPKSPCT 320 368 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:29:57 2016 done: Sat Nov 5 12:29:58 2016 Total Scan time: 6.830 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]