FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5361, 429 aa 1>>>pF1KB5361 429 - 429 aa - 429 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8273+/-0.000427; mu= -2.1876+/- 0.027 mean_var=286.8690+/-58.062, 0's: 0 Z-trim(119.5): 151 B-trim: 0 in 0/58 Lambda= 0.075724 statistics sampled from 33492 (33645) to 33492 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.394), width: 16 Scan time: 8.710 The best scores are: opt bits E(85289) NP_073570 (OMIM: 616916) stromal membrane-associat ( 429) 2926 333.1 8.7e-91 NP_001185907 (OMIM: 616916) stromal membrane-assoc ( 399) 2707 309.1 1.3e-83 XP_011540262 (OMIM: 616916) PREDICTED: stromal mem ( 403) 2696 307.9 3e-83 NP_001185908 (OMIM: 616916) stromal membrane-assoc ( 424) 2693 307.6 3.9e-83 NP_001185909 (OMIM: 616916) stromal membrane-assoc ( 349) 2360 271.1 3.1e-72 XP_016857582 (OMIM: 616916) PREDICTED: stromal mem ( 267) 1803 210.2 5.2e-54 NP_068759 (OMIM: 611372) stromal membrane-associat ( 440) 1296 155.0 3.6e-37 XP_011534349 (OMIM: 611372) PREDICTED: stromal mem ( 429) 1185 142.9 1.6e-33 NP_001268368 (OMIM: 611372) stromal membrane-assoc ( 436) 1185 142.9 1.6e-33 XP_011534347 (OMIM: 611372) PREDICTED: stromal mem ( 456) 758 96.2 1.8e-19 NP_001037770 (OMIM: 611372) stromal membrane-assoc ( 467) 758 96.2 1.8e-19 XP_005248817 (OMIM: 611372) PREDICTED: stromal mem ( 250) 691 88.7 1.8e-17 XP_011534348 (OMIM: 611372) PREDICTED: stromal mem ( 440) 654 84.9 4.6e-16 NP_001268369 (OMIM: 611372) stromal membrane-assoc ( 457) 643 83.7 1.1e-15 NP_060874 (OMIM: 608635) arf-GAP with dual PH doma ( 381) 333 49.7 1.5e-05 XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 339 50.6 1.6e-05 XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 339 50.6 1.6e-05 XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 339 50.6 1.6e-05 NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 339 50.7 1.6e-05 XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785) 339 50.7 1.6e-05 XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806) 339 50.7 1.7e-05 XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 339 50.7 1.7e-05 XP_016861537 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 339 50.7 1.7e-05 NP_055531 (OMIM: 607763) arf-GAP with coiled-coil, ( 740) 338 50.5 1.7e-05 XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP wit ( 820) 339 50.7 1.7e-05 XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP wit ( 841) 339 50.7 1.7e-05 NP_006860 (OMIM: 608114) arf-GAP with dual PH doma ( 374) 331 49.5 1.7e-05 XP_016861535 (OMIM: 607766) PREDICTED: arf-GAP wit ( 848) 339 50.7 1.7e-05 XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462) 323 48.7 3.7e-05 XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP wit ( 527) 323 48.8 4e-05 XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP wit ( 565) 323 48.8 4.3e-05 NP_001268229 (OMIM: 616813) arf-GAP with GTPase, A ( 580) 323 48.8 4.3e-05 XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP wit ( 580) 323 48.8 4.3e-05 XP_016867221 (OMIM: 616813) PREDICTED: arf-GAP wit ( 630) 323 48.8 4.6e-05 XP_011514082 (OMIM: 616813) PREDICTED: arf-GAP wit ( 683) 323 48.9 4.9e-05 NP_055729 (OMIM: 608651) arf-GAP with GTPase, ANK ( 804) 322 48.8 6e-05 XP_005246116 (OMIM: 608651) PREDICTED: arf-GAP wit ( 808) 322 48.8 6e-05 NP_114152 (OMIM: 616813) arf-GAP with GTPase, ANK ( 911) 323 49.0 6.1e-05 NP_001032208 (OMIM: 608651) arf-GAP with GTPase, A ( 857) 322 48.8 6.3e-05 XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP wit ( 882) 322 48.8 6.4e-05 XP_006712297 (OMIM: 608651) PREDICTED: arf-GAP wit ( 886) 322 48.8 6.4e-05 XP_011508851 (OMIM: 608651) PREDICTED: arf-GAP wit (1073) 322 48.9 7.4e-05 XP_011508850 (OMIM: 608651) PREDICTED: arf-GAP wit (1098) 322 48.9 7.5e-05 XP_016858771 (OMIM: 608651) PREDICTED: arf-GAP wit (1106) 322 48.9 7.6e-05 XP_011508849 (OMIM: 608651) PREDICTED: arf-GAP wit (1126) 322 48.9 7.7e-05 XP_006712300 (OMIM: 608651) PREDICTED: arf-GAP wit (1147) 322 48.9 7.8e-05 XP_006712302 (OMIM: 608651) PREDICTED: arf-GAP wit (1151) 322 48.9 7.8e-05 XP_011534350 (OMIM: 611372) PREDICTED: stromal mem ( 382) 310 47.2 8.5e-05 XP_016866659 (OMIM: 611372) PREDICTED: stromal mem ( 382) 310 47.2 8.5e-05 XP_016873902 (OMIM: 606908) PREDICTED: ADP-ribosyl ( 535) 311 47.5 0.0001 >>NP_073570 (OMIM: 616916) stromal membrane-associated p (429 aa) initn: 2926 init1: 2926 opt: 2926 Z-score: 1750.9 bits: 333.1 E(85289): 8.7e-91 Smith-Waterman score: 2926; 100.0% identity (100.0% similar) in 429 aa overlap (1-429:1-429) 10 20 30 40 50 60 pF1KB5 MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 HISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 HISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 KKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 TAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 TAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 VPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 PGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 GYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 GYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAAN 370 380 390 400 410 420 pF1KB5 QTLSPQMWK ::::::::: NP_073 QTLSPQMWK >>NP_001185907 (OMIM: 616916) stromal membrane-associate (399 aa) initn: 2707 init1: 2707 opt: 2707 Z-score: 1622.1 bits: 309.1 E(85289): 1.3e-83 Smith-Waterman score: 2707; 100.0% identity (100.0% similar) in 396 aa overlap (34-429:4-399) 10 20 30 40 50 60 pF1KB5 KSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHIS :::::::::::::::::::::::::::::: NP_001 MIFKGPRWASWNIGVFICIRCAGIHRNLGVHIS 10 20 30 70 80 90 100 110 120 pF1KB5 RVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 MDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 VMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 TPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYM 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 AGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTL 340 350 360 370 380 390 pF1KB5 SPQMWK :::::: NP_001 SPQMWK >>XP_011540262 (OMIM: 616916) PREDICTED: stromal membran (403 aa) initn: 2696 init1: 2696 opt: 2696 Z-score: 1615.5 bits: 307.9 E(85289): 3e-83 Smith-Waterman score: 2696; 99.7% identity (99.7% similar) in 396 aa overlap (34-429:8-403) 10 20 30 40 50 60 pF1KB5 KSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHIS : :::::::::::::::::::::::::::: XP_011 MRKLRLRKWPRWASWNIGVFICIRCAGIHRNLGVHIS 10 20 30 70 80 90 100 110 120 pF1KB5 RVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 MDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 VMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGV 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 TPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYM 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 AGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTL 340 350 360 370 380 390 pF1KB5 SPQMWK :::::: XP_011 SPQMWK 400 >>NP_001185908 (OMIM: 616916) stromal membrane-associate (424 aa) initn: 2693 init1: 2693 opt: 2693 Z-score: 1613.4 bits: 307.6 E(85289): 3.9e-83 Smith-Waterman score: 2693; 100.0% identity (100.0% similar) in 394 aa overlap (36-429:31-424) 10 20 30 40 50 60 pF1KB5 VKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRV :::::::::::::::::::::::::::::: NP_001 MGKVGRARFAQKDVLQIEEIGPVKLFVRDWPRWASWNIGVFICIRCAGIHRNLGVHISRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 NLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 MAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSP 370 380 390 400 410 420 pF1KB5 QMWK :::: NP_001 QMWK >>NP_001185909 (OMIM: 616916) stromal membrane-associate (349 aa) initn: 2360 init1: 2360 opt: 2360 Z-score: 1418.0 bits: 271.1 E(85289): 3.1e-72 Smith-Waterman score: 2360; 100.0% identity (100.0% similar) in 349 aa overlap (81-429:1-349) 60 70 80 90 100 110 pF1KB5 CAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAV :::::::::::::::::::::::::::::: NP_001 MQEMGNGKANRLYEAYLPETFRRPQIDPAV 10 20 30 120 130 140 150 160 170 pF1KB5 EGFIRDKYEKKKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGFIRDKYEKKKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDP 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 QLPRKSSPKSTAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLPRKSSPKSTAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVG 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 SMPTAGSAGSVPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMPTAGSAGSVPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQ 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 MAYPTAYPSFPGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAYPTAYPSFPGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGV 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 PNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQS 280 290 300 310 320 330 420 pF1KB5 MSGGNGQAANQTLSPQMWK ::::::::::::::::::: NP_001 MSGGNGQAANQTLSPQMWK 340 >>XP_016857582 (OMIM: 616916) PREDICTED: stromal membran (267 aa) initn: 1803 init1: 1803 opt: 1803 Z-score: 1090.6 bits: 210.2 E(85289): 5.2e-54 Smith-Waterman score: 1803; 100.0% identity (100.0% similar) in 267 aa overlap (163-429:1-267) 140 150 160 170 180 190 pF1KB5 FRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVMDLLGLDA :::::::::::::::::::::::::::::: XP_016 MPQKKEDPQLPRKSSPKSTAPVMDLLGLDA 10 20 30 200 210 220 230 240 250 pF1KB5 PVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENLNLFPEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENLNLFPEPG 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB5 SKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGS 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB5 MMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQT 160 170 180 190 200 210 380 390 400 410 420 pF1KB5 VYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSPQMWK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSPQMWK 220 230 240 250 260 >>NP_068759 (OMIM: 611372) stromal membrane-associated p (440 aa) initn: 1147 init1: 734 opt: 1296 Z-score: 788.4 bits: 155.0 E(85289): 3.6e-37 Smith-Waterman score: 1297; 50.1% identity (73.3% similar) in 445 aa overlap (4-429:9-440) 10 20 30 40 50 pF1KB5 MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIH :. : ...: .:..:: :::::.::::..:::::::::::::::::::::: NP_068 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIR ::::::::::::::::::: :::::::.::: :: :::: :::.::::: : ::: ::: NP_068 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 DKYEKKKYMDRS-LDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPR ::::::::.:.. . :. .::: . :. : ::: .:.. ::. :::.. :. NP_068 DKYEKKKYYDKNAIAITNKEKEKKKEEKK-REKEPEKPAKPLTAEKL---QKKDQQLEPK 130 140 150 160 170 180 190 200 210 220 pF1KB5 KS-SPKSTA-PVMDLLGLDAPVACSIANSKTS-NTLEKDLDL---LASVPSPSSS-GSRK :: :::..: :..::::::.:.. ..:..:. :. :::. . : : :.. . NP_068 KSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQ 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 VVGSMPTAGSAGSVPE-NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQT-PQMPTQAMF . : :.:.. ..: .:.:: : .::::..::::::::::::::. : :. : ..: NP_068 GTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVF 240 250 260 270 280 290 290 300 310 320 330 pF1KB5 MAPAQMAY----PTAYPSFP--GVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGY :.:... . :.:. .:: :: : . : .: : . : ::. : :: :. NP_068 MGPTNIPFTSQAPAAFQGFPSMGVPVPAA------PGLIGNVMGQSPSMMVG-MPMPNGF 300 310 320 330 340 340 350 360 370 380 390 pF1KB5 MGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFY ::. :...: .:.... : : :.:. . ::. .:. ::: ::.:.::.::::::.. NP_068 MGNAQTGVMPLPQNVVGPQ--GGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSIS 350 360 370 380 390 400 400 410 420 pF1KB5 GANGMMNYGQSMS---GGNGQAANQTLSPQMWK .:. ..:: : : .:....:::: :.:: NP_068 SATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK 410 420 430 440 >>XP_011534349 (OMIM: 611372) PREDICTED: stromal membran (429 aa) initn: 1032 init1: 734 opt: 1185 Z-score: 723.0 bits: 142.9 E(85289): 1.6e-33 Smith-Waterman score: 1186; 50.4% identity (73.1% similar) in 405 aa overlap (4-392:9-400) 10 20 30 40 50 pF1KB5 MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIH :. : ...: .:..:: :::::.::::..:::::::::::::::::::::: XP_011 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIR ::::::::::::::::::: :::::::.::: :: :::: :::.::::: : ::: ::: XP_011 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 DKYEKKKYMDRS-LDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPR ::::::::.:.. . :. .::: . :. : ::: .:.. ::. :::.. :. XP_011 DKYEKKKYYDKNAIAITNKEKEKKKEEKK-REKEPEKPAKPLTAEKL---QKKDQQLEPK 130 140 150 160 170 180 190 200 210 220 pF1KB5 KS-SPKSTA-PVMDLLGLDAPVACSIANSKTS-NTLEKDLDL---LASVPSPSSS-GSRK :: :::..: :..::::::.:.. ..:..:. :. :::. . : : :.. . XP_011 KSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQ 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 VVGSMPTAGSAGSVPE-NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQT-PQMPTQAMF . : :.:.. ..: .:.:: : .::::..::::::::::::::. : :. : ..: XP_011 GTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVF 240 250 260 270 280 290 290 300 310 320 330 pF1KB5 MAPAQMAY----PTAYPSFP--GVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGY :.:... . :.:. .:: :: : . : .: : . : ::. : :: :. XP_011 MGPTNIPFTSQAPAAFQGFPSMGVPVPAA------PGLIGNVMGQSPSMMVG-MPMPNGF 300 310 320 330 340 340 350 360 370 380 390 pF1KB5 MGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFY ::. :...: .:.... : : :.:. . ::. .:. ::: ::.:.:. :. XP_011 MGNAQTGVMPLPQNVVGPQ--GGMVGQMGAPQSKFGLPQAQQPQWSLSQIMQKGDAVLQH 350 360 370 380 390 400 400 410 420 pF1KB5 GANGMMNYGQSMSGGNGQAANQTLSPQMWK XP_011 SISAIYWPMTRWLKCPLVGMKT 410 420 >>NP_001268368 (OMIM: 611372) stromal membrane-associate (436 aa) initn: 1032 init1: 734 opt: 1185 Z-score: 722.9 bits: 142.9 E(85289): 1.6e-33 Smith-Waterman score: 1186; 50.4% identity (73.1% similar) in 405 aa overlap (4-392:9-400) 10 20 30 40 50 pF1KB5 MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIH :. : ...: .:..:: :::::.::::..:::::::::::::::::::::: NP_001 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIR ::::::::::::::::::: :::::::.::: :: :::: :::.::::: : ::: ::: NP_001 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 DKYEKKKYMDRS-LDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPR ::::::::.:.. . :. .::: . :. : ::: .:.. ::. :::.. :. NP_001 DKYEKKKYYDKNAIAITNKEKEKKKEEKK-REKEPEKPAKPLTAEKL---QKKDQQLEPK 130 140 150 160 170 180 190 200 210 220 pF1KB5 KS-SPKSTA-PVMDLLGLDAPVACSIANSKTS-NTLEKDLDL---LASVPSPSSS-GSRK :: :::..: :..::::::.:.. ..:..:. :. :::. . : : :.. . NP_001 KSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQ 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 VVGSMPTAGSAGSVPE-NLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQT-PQMPTQAMF . : :.:.. ..: .:.:: : .::::..::::::::::::::. : :. : ..: NP_001 GTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVF 240 250 260 270 280 290 290 300 310 320 330 pF1KB5 MAPAQMAY----PTAYPSFP--GVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGY :.:... . :.:. .:: :: : . : .: : . : ::. : :: :. NP_001 MGPTNIPFTSQAPAAFQGFPSMGVPVPAA------PGLIGNVMGQSPSMMVG-MPMPNGF 300 310 320 330 340 340 350 360 370 380 390 pF1KB5 MGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFY ::. :...: .:.... : : :.:. . ::. .:. ::: ::.:.:. :. NP_001 MGNAQTGVMPLPQNVVGPQ--GGMVGQMGAPQSKFGLPQAQQPQWSLSQIMQKGDAVLQH 350 360 370 380 390 400 400 410 420 pF1KB5 GANGMMNYGQSMSGGNGQAANQTLSPQMWK NP_001 SISAIYWPMTRWLKCPLVDESADGWHEYQ 410 420 430 >>XP_011534347 (OMIM: 611372) PREDICTED: stromal membran (456 aa) initn: 1073 init1: 674 opt: 758 Z-score: 470.6 bits: 96.2 E(85289): 1.8e-19 Smith-Waterman score: 1150; 47.6% identity (69.1% similar) in 431 aa overlap (4-392:9-427) 10 20 30 40 50 pF1KB5 MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIH :. : ...: .:..:: :::::.::::..:::::::::::::::::::::: XP_011 MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIR ::::::::::::::::::: :::::::.::: :: :::: :::.::::: : ::: ::: XP_011 RNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIR 70 80 90 100 110 120 120 130 140 pF1KB5 DKYEKKKYMDRS--------------------------LDINAFRKEKDDKWK-RGSEPV ::::::::.:.. .: : ..:::. : . . : XP_011 DKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKE 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB5 PEKKLEPVVFEKVKMPQKKEDPQLPRKS-SPKSTA-PVMDLLGLDAPVACSIANSKTS-N ::: .:.. ::. :::.. :.:: :::..: :..::::::.:.. ..:..:. XP_011 PEKPAKPLTAEKL---QKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVP 190 200 210 220 230 210 220 230 240 250 260 pF1KB5 TLEKDLDL---LASVPSPSSS-GSRKVVGSMPTAGSAGSVPE-NLNLFPEPGSKSEEIGK :. :::. . : : :.. . . : :.:.. ..: .:.:: : .::::..: XP_011 PLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAK 240 250 260 270 280 290 270 280 290 300 310 pF1KB5 KQLSKDSILSLYGSQT-PQMPTQAMFMAPAQMAY----PTAYPSFP--GVTPPNSIMGSM :::::::::::::. : :. : ..::.:... . :.:. .:: :: : . XP_011 KQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAA----- 300 310 320 330 340 350 320 330 340 350 360 370 pF1KB5 MPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTV : .: : . : ::. : :: :.::. :...: .:.... : : :.:. . ::. XP_011 -PGLIGNVMGQSPSMMVG-MPMPNGFMGNAQTGVMPLPQNVVGPQ--GGMVGQMGAPQSK 360 370 380 390 400 380 390 400 410 420 pF1KB5 YGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSPQMWK .:. ::: ::.:.:. :. XP_011 FGLPQAQQPQWSLSQIMQKGDAVLQHSISAIYWPMTRWLKCPLVGMKT 410 420 430 440 450 429 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:30:36 2016 done: Sat Nov 5 12:30:38 2016 Total Scan time: 8.710 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]