FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5370, 305 aa 1>>>pF1KB5370 305 - 305 aa - 305 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2540+/-0.000706; mu= 16.3444+/- 0.043 mean_var=69.8434+/-14.216, 0's: 0 Z-trim(110.3): 13 B-trim: 605 in 1/51 Lambda= 0.153466 statistics sampled from 11487 (11499) to 11487 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.353), width: 16 Scan time: 2.750 The best scores are: opt bits E(32554) CCDS1431.1 CYB5R1 gene_id:51706|Hs108|chr1 ( 305) 2055 463.6 8.7e-131 CCDS14040.1 CYB5R3 gene_id:1727|Hs108|chr22 ( 278) 1272 290.2 1.2e-78 CCDS33658.1 CYB5R3 gene_id:1727|Hs108|chr22 ( 301) 1272 290.2 1.3e-78 CCDS54535.1 CYB5R3 gene_id:1727|Hs108|chr22 ( 334) 1272 290.2 1.4e-78 CCDS7780.1 CYB5R2 gene_id:51700|Hs108|chr11 ( 276) 1179 269.6 1.9e-72 >>CCDS1431.1 CYB5R1 gene_id:51706|Hs108|chr1 (305 aa) initn: 2055 init1: 2055 opt: 2055 Z-score: 2461.5 bits: 463.6 E(32554): 8.7e-131 Smith-Waterman score: 2055; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305) 10 20 30 40 50 60 pF1KB5 MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 MIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQK 250 260 270 280 290 300 pF1KB5 MRFTY ::::: CCDS14 MRFTY >>CCDS14040.1 CYB5R3 gene_id:1727|Hs108|chr22 (278 aa) initn: 1296 init1: 1250 opt: 1272 Z-score: 1525.2 bits: 290.2 E(32554): 1.2e-78 Smith-Waterman score: 1272; 63.5% identity (85.9% similar) in 277 aa overlap (29-305:3-278) 10 20 30 40 50 60 pF1KB5 MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHN : .:: : .:: .:. :: :::.:. .::. CCDS14 MKLFQRST-PAITLESPDIKYPLRLIDREIISHD 10 20 30 70 80 90 100 110 120 pF1KB5 TKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKG :.:::::::. .: ::::::.:::::.::::.::.:::::..::.:.:.::::::::.: CCDS14 TRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLG .::::: ::::::::.:...::..:::::::::.: :::.: :.:.::: : :..:..: CCDS14 THPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 MIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW :::::::::::::.::::.: :.: : : :::::::::::.:: .::::. .. ::::: CCDS14 MIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLW 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 FTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQK .:::. :. : :..:::. .:::.::: : .. :::.::::::.: :: ::::..:. . CCDS14 YTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTE 220 230 240 250 260 270 pF1KB5 MRFTY :.. CCDS14 RCFVF >>CCDS33658.1 CYB5R3 gene_id:1727|Hs108|chr22 (301 aa) initn: 1296 init1: 1250 opt: 1272 Z-score: 1524.7 bits: 290.2 E(32554): 1.3e-78 Smith-Waterman score: 1272; 63.5% identity (85.9% similar) in 277 aa overlap (29-305:26-301) 10 20 30 40 50 60 pF1KB5 MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHN : .:: : .:: .:. :: :::.:. .::. CCDS33 MGAQLSTLGHMVLFPVWFLYSLLMKLFQRST-PAITLESPDIKYPLRLIDREIISHD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 TKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKG :.:::::::. .: ::::::.:::::.::::.::.:::::..::.:.:.::::::::.: CCDS33 TRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 VHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLG .::::: ::::::::.:...::..:::::::::.: :::.: :.:.::: : :..:..: CCDS33 THPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 MIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW :::::::::::::.::::.: :.: : : :::::::::::.:: .::::. .. ::::: CCDS33 MIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLW 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 FTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQK .:::. :. : :..:::. .:::.::: : .. :::.::::::.: :: ::::..:. . CCDS33 YTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTE 240 250 260 270 280 290 pF1KB5 MRFTY :.. CCDS33 RCFVF 300 >>CCDS54535.1 CYB5R3 gene_id:1727|Hs108|chr22 (334 aa) initn: 1296 init1: 1250 opt: 1272 Z-score: 1524.1 bits: 290.2 E(32554): 1.4e-78 Smith-Waterman score: 1272; 63.5% identity (85.9% similar) in 277 aa overlap (29-305:59-334) 10 20 30 40 50 pF1KB5 MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVS : .:: : .:: .:. :: :::.:. .: CCDS54 DGLDVERAESWELGHMVLFPVWFLYSLLMKLFQRST-PAITLESPDIKYPLRLIDREIIS 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB5 HNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYL :.:.:::::::. .: ::::::.:::::.::::.::.:::::..::.:.:.::::::::. CCDS54 HDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYF 90 100 110 120 130 140 120 130 140 150 160 170 pF1KB5 KGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKK : .::::: ::::::::.:...::..:::::::::.: :::.: :.:.::: : :..:. CCDS54 KDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKS 150 160 170 180 190 200 180 190 200 210 220 230 pF1KB5 LGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFK .::::::::::::::.::::.: :.: : : :::::::::::.:: .::::. .. ::: CCDS54 VGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFK 210 220 230 240 250 260 240 250 260 270 280 290 pF1KB5 LWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYS ::.:::. :. : :..:::. .:::.::: : .. :::.::::::.: :: ::::..:. CCDS54 LWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHP 270 280 290 300 310 320 300 pF1KB5 QKMRFTY . :.. CCDS54 TERCFVF 330 >>CCDS7780.1 CYB5R2 gene_id:51700|Hs108|chr11 (276 aa) initn: 1179 init1: 1179 opt: 1179 Z-score: 1414.0 bits: 269.6 E(32554): 1.9e-72 Smith-Waterman score: 1179; 58.8% identity (83.8% similar) in 272 aa overlap (34-305:5-276) 10 20 30 40 50 60 pF1KB5 QTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHNTKR :: .:: ::. :: : :..: .::::.: CCDS77 MNSRRREPITLQDPEAKYPLPLIEKEKISHNTRR 10 20 30 70 80 90 100 110 120 pF1KB5 FRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKGVHP :::.::. :.::::::... : ..::. ::.: ::::.::.:.:.:::.::.:.:.::: CCDS77 FRFGLPSPDHVLGLPVGNYVQLLAKIDNELVVRAYTPVSSDDDRGFVDLIIKIYFKNVHP 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 KFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLGMIA ..::::::.:::...:.:... :::: : : : : :...:.:.. : :. .: .::::: CCDS77 QYPEGGKMTQYLENMKIGETIFFRGPRGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 GGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLWFTL ::::::::::::: : : : : :. :.::::::.::..:..:::. .:..:.::.:: CCDS77 GGTGITPMLQLIRHITKDPSDRTRMSLIFANQTEEDILVRKELEEIARTHPDQFNLWYTL 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 DHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQKMRF :.:: : ::.::::::::.:::: :. ..:.:.:::::..: : ::::.::::.: : : CCDS77 DRPPIGWKYSSGFVTADMIKEHLPPPAKSTLILVCGPPPLIQTAAHPNLEKLGYTQDMIF 220 230 240 250 260 270 pF1KB5 TY :: CCDS77 TY 305 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:32:13 2016 done: Sat Nov 5 12:32:14 2016 Total Scan time: 2.750 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]