Result of FASTA (omim) for
pF1KB5387
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5387, 543 aa
1>>>pF1KB5387 543 - 543 aa - 543 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1347+/-0.000446; mu= 19.5747+/- 0.027
mean_var=68.9508+/-13.202, 0's: 0 Z-trim(111.4): 29 B-trim: 59 in 1/49
Lambda= 0.154456
statistics sampled from 19907 (19935) to 19907 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.234), width: 16
Scan time: 9.850
The best scores are: opt bits E(85289)
NP_001265524 (OMIM: 600592) DNA replication licens ( 543) 3538 797.9 0
NP_877577 (OMIM: 600592) DNA replication licensing ( 543) 3538 797.9 0
XP_005250405 (OMIM: 600592) PREDICTED: DNA replica ( 612) 3538 798.0 0
XP_016867706 (OMIM: 600592) PREDICTED: DNA replica ( 612) 3538 798.0 0
NP_005907 (OMIM: 600592) DNA replication licensing ( 719) 3538 798.0 0
XP_006724305 (OMIM: 602696) PREDICTED: DNA replica ( 732) 981 228.2 6.7e-59
NP_006730 (OMIM: 602696) DNA replication licensing ( 734) 981 228.2 6.8e-59
NP_877423 (OMIM: 602638,609981) DNA replication li ( 863) 967 225.2 6.7e-58
NP_005905 (OMIM: 602638,609981) DNA replication li ( 863) 967 225.2 6.7e-58
NP_001257401 (OMIM: 602693) DNA replication licens ( 818) 949 221.1 1e-56
NP_002379 (OMIM: 602693) DNA replication licensing ( 853) 949 221.1 1.1e-56
NP_004517 (OMIM: 116945,616968) DNA replication li ( 904) 932 217.4 1.5e-55
NP_060166 (OMIM: 610098,616185) DNA helicase MCM9 (1143) 906 211.6 1e-53
NP_005906 (OMIM: 223100,601806) DNA replication li ( 821) 894 208.9 5.1e-53
NP_877954 (OMIM: 608187,612885) DNA helicase MCM8 ( 824) 705 166.8 2.4e-40
XP_016883596 (OMIM: 608187,612885) PREDICTED: DNA ( 557) 624 148.6 4.8e-35
XP_016883595 (OMIM: 608187,612885) PREDICTED: DNA ( 776) 624 148.7 6.3e-35
NP_115874 (OMIM: 608187,612885) DNA helicase MCM8 ( 840) 624 148.7 6.7e-35
NP_001268449 (OMIM: 608187,612885) DNA helicase MC ( 840) 624 148.7 6.7e-35
NP_001268450 (OMIM: 608187,612885) DNA helicase MC ( 880) 559 134.2 1.6e-30
XP_016883594 (OMIM: 608187,612885) PREDICTED: DNA ( 880) 559 134.2 1.6e-30
XP_011527689 (OMIM: 608187,612885) PREDICTED: DNA ( 581) 526 126.8 1.9e-28
NP_001268451 (OMIM: 608187,612885) DNA helicase MC ( 793) 461 112.4 5.5e-24
NP_694987 (OMIM: 610098,616185) DNA helicase MCM9 ( 391) 359 89.4 2.2e-17
>>NP_001265524 (OMIM: 600592) DNA replication licensing (543 aa)
initn: 3538 init1: 3538 opt: 3538 Z-score: 4259.6 bits: 797.9 E(85289): 0
Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:1-543)
10 20 30 40 50 60
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 ITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI
490 500 510 520 530 540
pF1KB5 TFV
:::
NP_001 TFV
>>NP_877577 (OMIM: 600592) DNA replication licensing fac (543 aa)
initn: 3538 init1: 3538 opt: 3538 Z-score: 4259.6 bits: 797.9 E(85289): 0
Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:1-543)
10 20 30 40 50 60
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 YLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 LLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 AVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 AVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 ITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 ITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 DATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI
490 500 510 520 530 540
pF1KB5 TFV
:::
NP_877 TFV
>>XP_005250405 (OMIM: 600592) PREDICTED: DNA replication (612 aa)
initn: 3538 init1: 3538 opt: 3538 Z-score: 4258.9 bits: 798.0 E(85289): 0
Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:70-612)
10 20 30
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMC
::::::::::::::::::::::::::::::
XP_005 RVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMC
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB5 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB5 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB5 IAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVA
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB5 KSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDE
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB5 FDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQ
340 350 360 370 380 390
340 350 360 370 380 390
pF1KB5 LPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMC
400 410 420 430 440 450
400 410 420 430 440 450
pF1KB5 REKQPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REKQPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVE
460 470 480 490 500 510
460 470 480 490 500 510
pF1KB5 KEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVS
520 530 540 550 560 570
520 530 540
pF1KB5 RGFTPAQFQAALDEYEELNVWQVNASRTRITFV
:::::::::::::::::::::::::::::::::
XP_005 RGFTPAQFQAALDEYEELNVWQVNASRTRITFV
580 590 600 610
>>XP_016867706 (OMIM: 600592) PREDICTED: DNA replication (612 aa)
initn: 3538 init1: 3538 opt: 3538 Z-score: 4258.9 bits: 798.0 E(85289): 0
Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:70-612)
10 20 30
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMC
::::::::::::::::::::::::::::::
XP_016 RVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMC
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB5 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB5 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB5 IAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVA
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB5 KSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDE
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB5 FDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQ
340 350 360 370 380 390
340 350 360 370 380 390
pF1KB5 LPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMC
400 410 420 430 440 450
400 410 420 430 440 450
pF1KB5 REKQPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKQPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVE
460 470 480 490 500 510
460 470 480 490 500 510
pF1KB5 KEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVS
520 530 540 550 560 570
520 530 540
pF1KB5 RGFTPAQFQAALDEYEELNVWQVNASRTRITFV
:::::::::::::::::::::::::::::::::
XP_016 RGFTPAQFQAALDEYEELNVWQVNASRTRITFV
580 590 600 610
>>NP_005907 (OMIM: 600592) DNA replication licensing fac (719 aa)
initn: 3538 init1: 3538 opt: 3538 Z-score: 4257.9 bits: 798.0 E(85289): 0
Smith-Waterman score: 3538; 100.0% identity (100.0% similar) in 543 aa overlap (1-543:177-719)
10 20 30
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMC
::::::::::::::::::::::::::::::
NP_005 RVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMC
150 160 170 180 190 200
40 50 60 70 80 90
pF1KB5 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ
210 220 230 240 250 260
100 110 120 130 140 150
pF1KB5 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ
270 280 290 300 310 320
160 170 180 190 200 210
pF1KB5 IAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVA
330 340 350 360 370 380
220 230 240 250 260 270
pF1KB5 KSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDE
390 400 410 420 430 440
280 290 300 310 320 330
pF1KB5 FDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQ
450 460 470 480 490 500
340 350 360 370 380 390
pF1KB5 LPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMC
510 520 530 540 550 560
400 410 420 430 440 450
pF1KB5 REKQPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 REKQPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVE
570 580 590 600 610 620
460 470 480 490 500 510
pF1KB5 KEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCVS
630 640 650 660 670 680
520 530 540
pF1KB5 RGFTPAQFQAALDEYEELNVWQVNASRTRITFV
:::::::::::::::::::::::::::::::::
NP_005 RGFTPAQFQAALDEYEELNVWQVNASRTRITFV
690 700 710
>>XP_006724305 (OMIM: 602696) PREDICTED: DNA replication (732 aa)
initn: 771 init1: 602 opt: 981 Z-score: 1178.4 bits: 228.2 E(85289): 6.7e-59
Smith-Waterman score: 992; 37.0% identity (65.9% similar) in 481 aa overlap (8-464:172-647)
10 20 30
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQT
: .: . . : . . : ..:.:
XP_006 SDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYAL-P-RKCNT
150 160 170 180 190
40 50 60 70 80 90
pF1KB5 NRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQP
...: ... . . :: .:.:: : :: :..:: . . . . :
XP_006 DQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVP
200 210 220 230 240 250
100 110 120 130 140
pF1KB5 GDHVSVTGIFLPILRTGF-----RQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELT--
:..:.. ::. : . :. :. : . .:... : ... . . .: :: ..
XP_006 GNRVTIMGIY-SIKKFGLTTSRGRDRVGVGIRSSYIRVLGI-QVDTDGSGRSFAGAVSPQ
260 270 280 290 300 310
150 160 170 180 190 200
pF1KB5 -REELRQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINI
.::.:..: . :: .. :::: :.: :.:::. :: :: . : :. ::.::.
XP_006 EEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINL
320 330 340 350 360 370
210 220 230 240 250 260
pF1KB5 CLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLA
..::::.::::::..... .: . ::.:.:::..::::.:.:: : .. .::::.:::
XP_006 LMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLA
380 390 400 410 420 430
270 280 290 300 310 320
pF1KB5 DQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNP
: :: :::::::: : ::.::::.::::::::::::: ::::.:::.::::: ..::..
XP_006 DGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDE
440 450 460 470 480 490
330 340 350 360 370 380
pF1KB5 RRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE-PLDM
.. :.::.. ..:::::......:. ... :. ::.:. .: . . : .:.
XP_006 TKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDL
500 510 520 530 540 550
390 400 410 420 430
pF1KB5 KLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREA-WASKDATYTSA-----RTLLAI
....::.:: : : . :. . :. :: : .:. :. : : ::
XP_006 AKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAI
560 570 580 590 600 610
440 450 460 470 480 490
pF1KB5 LRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELV
.:.. ::..... . . ::.::.::...:
XP_006 VRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIE
620 630 640 650 660 670
500 510 520 530 540
pF1KB5 SGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV
XP_006 KQLKRRFAIGSQVSEHSIIKDFTKQLSLLSGQAKASETETDRDRDERQTELETAIE
680 690 700 710 720 730
>>NP_006730 (OMIM: 602696) DNA replication licensing fac (734 aa)
initn: 863 init1: 602 opt: 981 Z-score: 1178.4 bits: 228.2 E(85289): 6.8e-59
Smith-Waterman score: 992; 37.0% identity (65.9% similar) in 481 aa overlap (8-464:172-647)
10 20 30
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQT
: .: . . : . . : ..:.:
NP_006 SDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYAL-P-RKCNT
150 160 170 180 190
40 50 60 70 80 90
pF1KB5 NRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQP
...: ... . . :: .:.:: : :: :..:: . . . . :
NP_006 DQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVP
200 210 220 230 240 250
100 110 120 130 140
pF1KB5 GDHVSVTGIFLPILRTGF-----RQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELT--
:..:.. ::. : . :. :. : . .:... : ... . . .: :: ..
NP_006 GNRVTIMGIY-SIKKFGLTTSRGRDRVGVGIRSSYIRVLGI-QVDTDGSGRSFAGAVSPQ
260 270 280 290 300 310
150 160 170 180 190 200
pF1KB5 -REELRQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINI
.::.:..: . :: .. :::: :.: :.:::. :: :: . : :. ::.::.
NP_006 EEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINL
320 330 340 350 360 370
210 220 230 240 250 260
pF1KB5 CLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLA
..::::.::::::..... .: . ::.:.:::..::::.:.:: : .. .::::.:::
NP_006 LMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLA
380 390 400 410 420 430
270 280 290 300 310 320
pF1KB5 DQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNP
: :: :::::::: : ::.::::.::::::::::::: ::::.:::.::::: ..::..
NP_006 DGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDE
440 450 460 470 480 490
330 340 350 360 370 380
pF1KB5 RRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE-PLDM
.. :.::.. ..:::::......:. ... :. ::.:. .: . . : .:.
NP_006 TKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDL
500 510 520 530 540 550
390 400 410 420 430
pF1KB5 KLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREA-WASKDATYTSA-----RTLLAI
....::.:: : : . :. . :. :: : .:. :. : : ::
NP_006 AKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAI
560 570 580 590 600 610
440 450 460 470 480 490
pF1KB5 LRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELV
.:.. ::..... . . ::.::.::...:
NP_006 VRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIE
620 630 640 650 660 670
500 510 520 530 540
pF1KB5 SGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV
NP_006 KQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK
680 690 700 710 720 730
>>NP_877423 (OMIM: 602638,609981) DNA replication licens (863 aa)
initn: 934 init1: 696 opt: 967 Z-score: 1160.5 bits: 225.2 E(85289): 6.7e-58
Smith-Waterman score: 1079; 38.4% identity (68.3% similar) in 542 aa overlap (1-524:299-826)
10 20 30
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMC
: : . :. :. : .. . .:
NP_877 KNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVC
270 280 290 300 310 320
40 50 60 70 80 90
pF1KB5 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ
.:.:..: . : : : : .:.:: ...:.:. :... ...... . .:
NP_877 --GRCHTTHS---MALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQ
330 340 350 360 370 380
100 110 120 130 140
pF1KB5 PGDHVSVTGIFLPI-LRTGFRQVVQGLLSETYLEAHRIVKMNKSED---DESGAGELTRE
:::.:.::::. . .:.. : . .:.... . : . .. :: . .: :
NP_877 PGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSE
390 400 410 420 430 440
150 160 170 180 190
pF1KB5 E----LRQIAEE-DFYEKLAASIAPEIYGHEDVKKALLLLLVGGV--DQSPRGM-KIRGN
. :...... :.::.::...:: :: :::.::..:: : ::. : : : :.:..
NP_877 KRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAE
450 460 470 480 490 500
200 210 220 230 240 250
pF1KB5 INICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGAL
::: : ::::..:::::.:. :.::.:::.:.:::.::::: :..: . .:.:. :::
NP_877 INILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGAL
510 520 530 540 550 560
260 270 280 290 300 310
pF1KB5 VLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR
::.:.:.::::::::: :. :...::::::::.:::::::. :::: :.:::::: ..
NP_877 VLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQ
570 580 590 600 610 620
320 330 340 350 360 370
pF1KB5 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPL
.::... .::::: .:::::::..:. : :. : :::.:.. .. .:.. .. : :
NP_877 WNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQ-AEEELL
630 640 650 660 670 680
380 390 400 410 420 430
pF1KB5 DMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLS
:: ... :::. . .: . : .. . :::.::. .:. . . : : ...::.
NP_877 DMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRK-IGSSRGMVSAYPRQLESLIRLA
690 700 710 720 730 740
440 450 460 470 480 490
pF1KB5 TALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPA--DV-IFATVRELVS
: :..:. . :: ::.:: :: ...: :.: : . :. :..: .:
NP_877 EAHAKVRLSNKVEAIDVEEAKRLH---REAL----KQSATDPRTGIVDISILTTGMSATS
750 760 770 780 790
500 510 520 530 540
pF1KB5 GGRSVRFSEAEQRCV-SRGFTPA-QFQAALDEYEELNVWQVNASRTRITFV
:. ...:: .. . :.: ::: ..: ...
NP_877 RKRKEELAEALKKLILSKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLT
800 810 820 830 840 850
NP_877 VTGKTVRLL
860
>>NP_005905 (OMIM: 602638,609981) DNA replication licens (863 aa)
initn: 934 init1: 696 opt: 967 Z-score: 1160.5 bits: 225.2 E(85289): 6.7e-58
Smith-Waterman score: 1079; 38.4% identity (68.3% similar) in 542 aa overlap (1-524:299-826)
10 20 30
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMC
: : . :. :. : .. . .:
NP_005 KNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVC
270 280 290 300 310 320
40 50 60 70 80 90
pF1KB5 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ
.:.:..: . : : : : .:.:: ...:.:. :... ...... . .:
NP_005 --GRCHTTHS---MALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQ
330 340 350 360 370 380
100 110 120 130 140
pF1KB5 PGDHVSVTGIFLPI-LRTGFRQVVQGLLSETYLEAHRIVKMNKSED---DESGAGELTRE
:::.:.::::. . .:.. : . .:.... . : . .. :: . .: :
NP_005 PGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSE
390 400 410 420 430 440
150 160 170 180 190
pF1KB5 E----LRQIAEE-DFYEKLAASIAPEIYGHEDVKKALLLLLVGGV--DQSPRGM-KIRGN
. :...... :.::.::...:: :: :::.::..:: : ::. : : : :.:..
NP_005 KRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAE
450 460 470 480 490 500
200 210 220 230 240 250
pF1KB5 INICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGAL
::: : ::::..:::::.:. :.::.:::.:.:::.::::: :..: . .:.:. :::
NP_005 INILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGAL
510 520 530 540 550 560
260 270 280 290 300 310
pF1KB5 VLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR
::.:.:.::::::::: :. :...::::::::.:::::::. :::: :.:::::: ..
NP_005 VLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQ
570 580 590 600 610 620
320 330 340 350 360 370
pF1KB5 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPL
.::... .::::: .:::::::..:. : :. : :::.:.. .. .:.. .. : :
NP_005 WNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQ-AEEELL
630 640 650 660 670 680
380 390 400 410 420 430
pF1KB5 DMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLS
:: ... :::. . .: . : .. . :::.::. .:. . . : : ...::.
NP_005 DMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRK-IGSSRGMVSAYPRQLESLIRLA
690 700 710 720 730 740
440 450 460 470 480 490
pF1KB5 TALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPA--DV-IFATVRELVS
: :..:. . :: ::.:: :: ...: :.: : . :. :..: .:
NP_005 EAHAKVRLSNKVEAIDVEEAKRLH---REAL----KQSATDPRTGIVDISILTTGMSATS
750 760 770 780 790
500 510 520 530 540
pF1KB5 GGRSVRFSEAEQRCV-SRGFTPA-QFQAALDEYEELNVWQVNASRTRITFV
:. ...:: .. . :.: ::: ..: ...
NP_005 RKRKEELAEALKKLILSKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLT
800 810 820 830 840 850
NP_005 VTGKTVRLL
860
>>NP_001257401 (OMIM: 602693) DNA replication licensing (818 aa)
initn: 821 init1: 735 opt: 949 Z-score: 1139.2 bits: 221.1 E(85289): 1e-56
Smith-Waterman score: 1017; 38.8% identity (65.3% similar) in 510 aa overlap (27-479:175-679)
10 20 30 40 50
pF1KB5 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTR-G-SRFI
:. ::. ... :.:. : : .
NP_001 SLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYK
150 160 170 180 190 200
60 70 80 90 100 110
pF1KB5 KFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQV
: . .:: ...:.:..:::. :... . . :.:::.:.:.: . :: . :.
NP_001 DHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGY---
210 220 230 240 250 260
120 130 140 150 160 170
pF1KB5 VQGLLSETYLEAHRIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGH
..: . .: : : . .:.:. . .: .... ... . .:....:: :.:: :.::
NP_001 TSGTF-RTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGH
270 280 290 300 310 320
180 190 200 210 220 230
pF1KB5 EDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG
. ::::.: ::.:::... : .:::.::: :.:::.::::::: :. :::. :::
NP_001 DYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTG
330 340 350 360 370 380
240 250 260 270 280 290
pF1KB5 RGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQT
:::::::::::: :. .:: ::.::.::::.:: ::::::::.. :::::::::::
NP_001 RGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGR
390 400 410 420 430 440
300 310 320 330 340 350
pF1KB5 ISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPD
..:::::: . ::::::.::::::.::::. .. .:: : .::::::::... :. :
NP_001 VTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMD
450 460 470 480 490 500
360 370 380
pF1KB5 RDNDLRLAQHITYVHQHSRQP--------P---------------SQFEPLDMKL-----
..: ....:. .:.. : : : :: . : ..
NP_001 PEQDREISDHVLRMHRY-RAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHD
510 520 530 540 550
390 400 410 420
pF1KB5 ------------------MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATY
:..:: . . .:.. . : ::. : ..: . :.:..
NP_001 NLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTAR
560 570 580 590 600 610
430 440 450 460 470
pF1KB5 TS---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS--KDSLLGDKGQTARTQ
:: :::: ...::.:: :. :: .:. .:..::..:.... : : .: . :..
NP_001 TSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSE
620 630 640 650 660 670
480 490 500 510 520 530
pF1KB5 RPADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTR
NP_001 DESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQ
680 690 700 710 720 730
543 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:45:22 2016 done: Fri Nov 4 21:45:23 2016
Total Scan time: 9.850 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]