FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5389, 479 aa 1>>>pF1KB5389 479 - 479 aa - 479 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0003+/-0.000417; mu= 14.5898+/- 0.026 mean_var=78.8088+/-15.189, 0's: 0 Z-trim(112.0): 142 B-trim: 263 in 1/49 Lambda= 0.144473 statistics sampled from 20578 (20766) to 20578 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.243), width: 16 Scan time: 8.910 The best scores are: opt bits E(85289) NP_009173 (OMIM: 605812) ATP-dependent RNA helicas ( 479) 3108 657.7 2e-188 XP_011521134 (OMIM: 605812) PREDICTED: ATP-depende ( 539) 3108 657.7 2.2e-188 XP_011521136 (OMIM: 605812) PREDICTED: ATP-depende ( 484) 2990 633.1 5.1e-181 XP_006721190 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 2430 516.4 5.5e-146 NP_001244103 (OMIM: 605812) ATP-dependent RNA heli ( 370) 2430 516.4 5.5e-146 XP_016878379 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 2430 516.4 5.5e-146 NP_001014449 (OMIM: 605812) ATP-dependent RNA heli ( 370) 2430 516.4 5.5e-146 NP_001244102 (OMIM: 605812) ATP-dependent RNA heli ( 370) 2430 516.4 5.5e-146 NP_001014451 (OMIM: 605812) ATP-dependent RNA heli ( 448) 2289 487.0 4.6e-137 NP_001244101 (OMIM: 605812) ATP-dependent RNA heli ( 453) 2289 487.0 4.6e-137 XP_011521135 (OMIM: 605812) PREDICTED: ATP-depende ( 508) 2289 487.0 5.1e-137 NP_001244104 (OMIM: 605812) ATP-dependent RNA heli ( 328) 2161 460.3 3.7e-129 NP_037396 (OMIM: 607663) ATP-dependent RNA helicas ( 483) 2074 442.2 1.5e-123 XP_011541093 (OMIM: 607663) PREDICTED: ATP-depende ( 482) 2067 440.7 4.1e-123 XP_011541092 (OMIM: 607663) PREDICTED: ATP-depende ( 486) 2067 440.7 4.2e-123 NP_001317367 (OMIM: 607663) ATP-dependent RNA heli ( 369) 1797 384.4 2.9e-106 NP_001958 (OMIM: 601102) eukaryotic initiation fac ( 407) 923 202.3 2.1e-51 NP_001407 (OMIM: 602641) eukaryotic initiation fac ( 406) 915 200.6 6.8e-51 NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 865 190.2 9.4e-48 NP_004631 (OMIM: 142560) spliceosome RNA helicase ( 428) 724 160.8 6.9e-39 NP_542165 (OMIM: 142560) spliceosome RNA helicase ( 428) 724 160.8 6.9e-39 NP_004388 (OMIM: 600326) probable ATP-dependent RN ( 483) 719 159.8 1.6e-38 XP_005271474 (OMIM: 600326) PREDICTED: probable AT ( 483) 719 159.8 1.6e-38 NP_001244120 (OMIM: 600326) probable ATP-dependent ( 483) 719 159.8 1.6e-38 NP_001191439 (OMIM: 602641) eukaryotic initiation ( 347) 686 152.8 1.4e-36 NP_009135 (OMIM: 606168) probable ATP-dependent RN ( 824) 679 151.5 8.1e-36 XP_011523824 (OMIM: 268305,608546) PREDICTED: euka ( 390) 656 146.6 1.2e-34 NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 588 132.5 2.5e-30 XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775) 550 124.6 9.5e-28 NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 550 124.7 1.1e-27 XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 550 124.7 1.1e-27 XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 550 124.7 1.1e-27 NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 550 124.7 1.1e-27 NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796) 545 123.6 2e-27 XP_011522561 (OMIM: 613369) PREDICTED: ATP-depende ( 674) 521 118.6 5.6e-26 XP_011540947 (OMIM: 600326) PREDICTED: probable AT ( 434) 514 117.0 1e-25 NP_001278405 (OMIM: 612500) probable ATP-dependent ( 491) 513 116.8 1.3e-25 XP_011522534 (OMIM: 612500) PREDICTED: probable AT ( 581) 513 116.9 1.6e-25 NP_008941 (OMIM: 612500) probable ATP-dependent RN ( 599) 513 116.9 1.6e-25 XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 505 115.2 5.2e-25 NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 505 115.2 5.2e-25 XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 505 115.2 5.2e-25 XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 505 115.2 5.2e-25 XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 490 112.0 3.4e-24 XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 490 112.1 4e-24 XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 490 112.1 4e-24 NP_076977 (OMIM: 611665) ATP-dependent RNA helicas ( 881) 493 112.8 4e-24 NP_001104792 (OMIM: 611665) ATP-dependent RNA heli ( 882) 493 112.8 4e-24 XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 490 112.1 4.5e-24 NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 490 112.1 4.7e-24 >>NP_009173 (OMIM: 605812) ATP-dependent RNA helicase DD (479 aa) initn: 3108 init1: 3108 opt: 3108 Z-score: 3503.9 bits: 657.7 E(85289): 2e-188 Smith-Waterman score: 3108; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479) 10 20 30 40 50 60 pF1KB5 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 430 440 450 460 470 >>XP_011521134 (OMIM: 605812) PREDICTED: ATP-dependent R (539 aa) initn: 3108 init1: 3108 opt: 3108 Z-score: 3503.1 bits: 657.7 E(85289): 2.2e-188 Smith-Waterman score: 3108; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:61-539) 10 20 30 pF1KB5 MATDSWALAVDEQEAAAESLSNLHLKEEKI :::::::::::::::::::::::::::::: XP_011 AEPAANPRSPRSLVPSLESTSTSVPPAPGTMATDSWALAVDEQEAAAESLSNLHLKEEKI 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB5 KPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYS 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB5 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB5 AMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKIS 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB5 EQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQM 280 290 300 310 320 330 280 290 300 310 320 330 pF1KB5 LLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGA 340 350 360 370 380 390 340 350 360 370 380 390 pF1KB5 ITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTT 400 410 420 430 440 450 400 410 420 430 440 450 pF1KB5 NVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMN 460 470 480 490 500 510 460 470 pF1KB5 ILNRIQEHFNKKIERLDTDDLDEIEKIAN ::::::::::::::::::::::::::::: XP_011 ILNRIQEHFNKKIERLDTDDLDEIEKIAN 520 530 >>XP_011521136 (OMIM: 605812) PREDICTED: ATP-dependent R (484 aa) initn: 2990 init1: 2990 opt: 2990 Z-score: 3370.9 bits: 633.1 E(85289): 5.1e-181 Smith-Waterman score: 2990; 100.0% identity (100.0% similar) in 460 aa overlap (20-479:25-484) 10 20 30 40 50 pF1KB5 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKED :::::::::::::::::::::::::::::::::::: XP_011 MAGAAGRVQDRALRRFPITLPVGDLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 SKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 LQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 IKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 KLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 EGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKD 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 GNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIE 430 440 450 460 470 480 pF1KB5 KIAN :::: XP_011 KIAN >>XP_006721190 (OMIM: 605812) PREDICTED: ATP-dependent R (370 aa) initn: 2430 init1: 2430 opt: 2430 Z-score: 2741.9 bits: 516.4 E(85289): 5.5e-146 Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 370 aa overlap (110-479:1-370) 80 90 100 110 120 130 pF1KB5 LQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQ :::::::::::::::::::::::::::::: XP_006 MGFNRPSKIQENALPLMLAEPPQNLIAQSQ 10 20 30 140 150 160 170 180 190 pF1KB5 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB5 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB5 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA 280 290 300 310 320 330 440 450 460 470 pF1KB5 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN :::::::::::::::::::::::::::::::::::::::: XP_006 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 340 350 360 370 >>NP_001244103 (OMIM: 605812) ATP-dependent RNA helicase (370 aa) initn: 2430 init1: 2430 opt: 2430 Z-score: 2741.9 bits: 516.4 E(85289): 5.5e-146 Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 370 aa overlap (110-479:1-370) 80 90 100 110 120 130 pF1KB5 LQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQ :::::::::::::::::::::::::::::: NP_001 MGFNRPSKIQENALPLMLAEPPQNLIAQSQ 10 20 30 140 150 160 170 180 190 pF1KB5 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB5 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB5 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA 280 290 300 310 320 330 440 450 460 470 pF1KB5 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN :::::::::::::::::::::::::::::::::::::::: NP_001 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 340 350 360 370 >>XP_016878379 (OMIM: 605812) PREDICTED: ATP-dependent R (370 aa) initn: 2430 init1: 2430 opt: 2430 Z-score: 2741.9 bits: 516.4 E(85289): 5.5e-146 Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 370 aa overlap (110-479:1-370) 80 90 100 110 120 130 pF1KB5 LQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQ :::::::::::::::::::::::::::::: XP_016 MGFNRPSKIQENALPLMLAEPPQNLIAQSQ 10 20 30 140 150 160 170 180 190 pF1KB5 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB5 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB5 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA 280 290 300 310 320 330 440 450 460 470 pF1KB5 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN :::::::::::::::::::::::::::::::::::::::: XP_016 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 340 350 360 370 >>NP_001014449 (OMIM: 605812) ATP-dependent RNA helicase (370 aa) initn: 2430 init1: 2430 opt: 2430 Z-score: 2741.9 bits: 516.4 E(85289): 5.5e-146 Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 370 aa overlap (110-479:1-370) 80 90 100 110 120 130 pF1KB5 LQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQ :::::::::::::::::::::::::::::: NP_001 MGFNRPSKIQENALPLMLAEPPQNLIAQSQ 10 20 30 140 150 160 170 180 190 pF1KB5 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB5 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB5 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA 280 290 300 310 320 330 440 450 460 470 pF1KB5 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN :::::::::::::::::::::::::::::::::::::::: NP_001 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 340 350 360 370 >>NP_001244102 (OMIM: 605812) ATP-dependent RNA helicase (370 aa) initn: 2430 init1: 2430 opt: 2430 Z-score: 2741.9 bits: 516.4 E(85289): 5.5e-146 Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 370 aa overlap (110-479:1-370) 80 90 100 110 120 130 pF1KB5 LQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQ :::::::::::::::::::::::::::::: NP_001 MGFNRPSKIQENALPLMLAEPPQNLIAQSQ 10 20 30 140 150 160 170 180 190 pF1KB5 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVR 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB5 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDE 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERF 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB5 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLA 280 290 300 310 320 330 440 450 460 470 pF1KB5 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN :::::::::::::::::::::::::::::::::::::::: NP_001 VNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 340 350 360 370 >>NP_001014451 (OMIM: 605812) ATP-dependent RNA helicase (448 aa) initn: 2289 init1: 2289 opt: 2289 Z-score: 2581.8 bits: 487.0 E(85289): 4.6e-137 Smith-Waterman score: 2829; 93.5% identity (93.5% similar) in 479 aa overlap (1-479:1-448) 10 20 30 40 50 60 pF1KB5 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE ::::::::::::::::::::::::::::::::::::::: NP_001 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL--------------------- 70 80 90 130 140 150 160 170 180 pF1KB5 NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----------PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB5 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB5 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB5 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 330 340 350 360 370 380 430 440 450 460 470 pF1KB5 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 390 400 410 420 430 440 >>NP_001244101 (OMIM: 605812) ATP-dependent RNA helicase (453 aa) initn: 2289 init1: 2289 opt: 2289 Z-score: 2581.7 bits: 487.0 E(85289): 4.6e-137 Smith-Waterman score: 2711; 93.3% identity (93.3% similar) in 460 aa overlap (20-479:25-453) 10 20 30 40 50 pF1KB5 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKED :::::::::::::::::::::::::::::::::::: NP_001 MAGAAGRVQDRALRRFPITLPVGDLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKED 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRP :::::::::::::::::::::::::::::::::::::::::::: NP_001 RAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL---------------- 70 80 90 100 120 130 140 150 160 170 pF1KB5 SKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELA ::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---------------PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELA 110 120 130 140 180 190 200 210 220 230 pF1KB5 LQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKK 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 IKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVI 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 KLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSK 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB5 EGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKD 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB5 GNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIE 390 400 410 420 430 440 pF1KB5 KIAN :::: NP_001 KIAN 450 479 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:43:57 2016 done: Fri Nov 4 21:43:58 2016 Total Scan time: 8.910 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]