FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5394, 593 aa 1>>>pF1KB5394 593 - 593 aa - 593 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.4800+/-0.00102; mu= -6.2925+/- 0.062 mean_var=383.3509+/-78.026, 0's: 0 Z-trim(115.3): 23 B-trim: 0 in 0/55 Lambda= 0.065505 statistics sampled from 15800 (15819) to 15800 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.486), width: 16 Scan time: 3.090 The best scores are: opt bits E(32554) CCDS2138.1 BIN1 gene_id:274|Hs108|chr2 ( 593) 3976 389.7 5.5e-108 CCDS2139.1 BIN1 gene_id:274|Hs108|chr2 ( 550) 2233 225.0 2e-58 CCDS2140.1 BIN1 gene_id:274|Hs108|chr2 ( 506) 2215 223.2 6.2e-58 CCDS42743.1 BIN1 gene_id:274|Hs108|chr2 ( 475) 1182 125.6 1.4e-28 CCDS42744.1 BIN1 gene_id:274|Hs108|chr2 ( 482) 1162 123.7 5.4e-28 CCDS2137.1 BIN1 gene_id:274|Hs108|chr2 ( 454) 1161 123.6 5.5e-28 CCDS2142.1 BIN1 gene_id:274|Hs108|chr2 ( 518) 1162 123.7 5.7e-28 CCDS2141.1 BIN1 gene_id:274|Hs108|chr2 ( 497) 1156 123.1 8.1e-28 CCDS82508.1 BIN1 gene_id:274|Hs108|chr2 ( 424) 1146 122.1 1.4e-27 CCDS46403.1 BIN1 gene_id:274|Hs108|chr2 ( 439) 1138 121.4 2.4e-27 CCDS2143.1 BIN1 gene_id:274|Hs108|chr2 ( 409) 1133 120.9 3.2e-27 CCDS47574.1 AMPH gene_id:273|Hs108|chr7 ( 653) 845 93.9 7e-19 CCDS5456.1 AMPH gene_id:273|Hs108|chr7 ( 695) 836 93.0 1.3e-18 CCDS8811.2 BIN2 gene_id:51411|Hs108|chr12 ( 597) 783 88.0 3.8e-17 CCDS76561.1 BIN2 gene_id:51411|Hs108|chr12 ( 539) 693 79.4 1.3e-14 >>CCDS2138.1 BIN1 gene_id:274|Hs108|chr2 (593 aa) initn: 3976 init1: 3976 opt: 3976 Z-score: 2052.1 bits: 389.7 E(32554): 5.5e-108 Smith-Waterman score: 3976; 100.0% identity (100.0% similar) in 593 aa overlap (1-593:1-593) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 490 500 510 520 530 540 550 560 570 580 590 pF1KB5 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 550 560 570 580 590 >>CCDS2139.1 BIN1 gene_id:274|Hs108|chr2 (550 aa) initn: 2241 init1: 2204 opt: 2233 Z-score: 1162.3 bits: 225.0 E(32554): 2e-58 Smith-Waterman score: 3587; 92.7% identity (92.7% similar) in 593 aa overlap (1-593:1-550) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS :::::::::::::::::::::::::::::::::: CCDS21 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-------------------------- 310 320 330 370 380 390 400 410 420 pF1KB5 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW ::::::::::::::::::::::::::::::::::::::::::: CCDS21 -----------------FEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW 340 350 360 370 430 440 450 460 470 480 pF1KB5 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB5 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 440 450 460 470 480 490 550 560 570 580 590 pF1KB5 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 500 510 520 530 540 550 >>CCDS2140.1 BIN1 gene_id:274|Hs108|chr2 (506 aa) initn: 2280 init1: 2210 opt: 2215 Z-score: 1153.6 bits: 223.2 E(32554): 6.2e-58 Smith-Waterman score: 3179; 85.3% identity (85.3% similar) in 593 aa overlap (1-593:1-506) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS :::::::::::::::::::::::::::::::::: CCDS21 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-------------------------- 310 320 330 370 380 390 400 410 420 pF1KB5 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW CCDS21 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KB5 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 -PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB5 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 400 410 420 430 440 450 550 560 570 580 590 pF1KB5 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 460 470 480 490 500 >>CCDS42743.1 BIN1 gene_id:274|Hs108|chr2 (475 aa) initn: 2281 init1: 1162 opt: 1182 Z-score: 626.4 bits: 125.6 E(32554): 1.4e-28 Smith-Waterman score: 2897; 80.1% identity (80.1% similar) in 593 aa overlap (1-593:1-475) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::: CCDS42 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 180 190 200 250 260 270 280 290 300 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB5 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS :::::::::::::::::::::::::::::::::: CCDS42 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-------------------------- 270 280 290 300 370 380 390 400 410 420 pF1KB5 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW CCDS42 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KB5 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 -PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 310 320 330 340 350 360 490 500 510 520 530 540 pF1KB5 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 370 380 390 400 410 420 550 560 570 580 590 pF1KB5 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 430 440 450 460 470 >>CCDS42744.1 BIN1 gene_id:274|Hs108|chr2 (482 aa) initn: 2073 init1: 1159 opt: 1162 Z-score: 616.1 bits: 123.7 E(32554): 5.4e-28 Smith-Waterman score: 2956; 81.3% identity (81.3% similar) in 593 aa overlap (1-593:1-482) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::: CCDS42 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 180 190 200 250 260 270 280 290 300 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB5 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB5 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW ::::::::::::::::: CCDS42 LFEDTFVPEISVTTPSQ------------------------------------------- 330 340 430 440 450 460 470 480 pF1KB5 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET ::::::::::::::::::::::: CCDS42 -------------------------------------PAEASEVAGGTQPAAGAQEPGET 350 360 490 500 510 520 530 540 pF1KB5 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 370 380 390 400 410 420 550 560 570 580 590 pF1KB5 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 430 440 450 460 470 480 >>CCDS2137.1 BIN1 gene_id:274|Hs108|chr2 (454 aa) initn: 2117 init1: 1133 opt: 1161 Z-score: 615.9 bits: 123.6 E(32554): 5.5e-28 Smith-Waterman score: 2537; 72.2% identity (72.2% similar) in 608 aa overlap (1-593:1-454) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::: CCDS21 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 180 190 200 250 260 270 280 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- ::::::::::::::::::::::::::::::::::::::::::::: CCDS21 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 210 220 230 240 250 260 290 300 310 320 330 340 pF1KB5 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ----------- 270 280 290 300 310 350 360 370 380 390 400 pF1KB5 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPV CCDS21 ------------------------------------------------------------ 410 420 430 440 450 460 pF1KB5 KAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVA :::::::: CCDS21 ----------------------------------------------------PAEASEVA 320 470 480 490 500 510 520 pF1KB5 GGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 GGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV 330 340 350 360 370 380 530 540 550 560 570 580 pF1KB5 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP 390 400 410 420 430 440 590 pF1KB5 ENFTERVP :::::::: CCDS21 ENFTERVP 450 >>CCDS2142.1 BIN1 gene_id:274|Hs108|chr2 (518 aa) initn: 2305 init1: 1162 opt: 1162 Z-score: 615.7 bits: 123.7 E(32554): 5.7e-28 Smith-Waterman score: 3276; 87.4% identity (87.4% similar) in 593 aa overlap (1-593:1-518) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::: CCDS21 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 180 190 200 250 260 270 280 290 300 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB5 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB5 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW ::::::::::::::::: CCDS21 LFEDTFVPEISVTTPSQ------------------------------------------- 330 340 430 440 450 460 470 480 pF1KB5 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 -PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB5 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 410 420 430 440 450 460 550 560 570 580 590 pF1KB5 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 470 480 490 500 510 >>CCDS2141.1 BIN1 gene_id:274|Hs108|chr2 (497 aa) initn: 2073 init1: 1133 opt: 1156 Z-score: 612.9 bits: 123.1 E(32554): 8.1e-28 Smith-Waterman score: 2916; 79.3% identity (79.3% similar) in 608 aa overlap (1-593:1-497) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::: CCDS21 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 180 190 200 250 260 270 280 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- ::::::::::::::::::::::::::::::::::::::::::::: CCDS21 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 210 220 230 240 250 260 290 300 310 320 330 340 pF1KB5 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB5 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPV :::::::::::::::::::::::::::::::: CCDS21 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ---------------------------- 330 340 350 360 410 420 430 440 450 460 pF1KB5 KAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVA :::::::: CCDS21 ----------------------------------------------------PAEASEVA 470 480 490 500 510 520 pF1KB5 GGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 GGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV 370 380 390 400 410 420 530 540 550 560 570 580 pF1KB5 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP 430 440 450 460 470 480 590 pF1KB5 ENFTERVP :::::::: CCDS21 ENFTERVP 490 >>CCDS82508.1 BIN1 gene_id:274|Hs108|chr2 (424 aa) initn: 1932 init1: 1133 opt: 1146 Z-score: 608.7 bits: 122.1 E(32554): 1.4e-27 Smith-Waterman score: 2291; 67.3% identity (67.3% similar) in 608 aa overlap (1-593:1-424) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::: CCDS82 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 180 190 200 250 260 270 280 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- ::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 210 220 230 240 250 260 290 300 310 320 330 340 pF1KB5 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ----------- 270 280 290 300 310 350 360 370 380 390 400 pF1KB5 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPV CCDS82 ------------------------------------------------------------ 410 420 430 440 450 460 pF1KB5 KAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVA CCDS82 ------------------------------------------------------------ 470 480 490 500 510 520 pF1KB5 GGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV :::::::::::::::::::::::::::::::::::::: CCDS82 ----------------------SSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV 320 330 340 350 530 540 550 560 570 580 pF1KB5 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP 360 370 380 390 400 410 590 pF1KB5 ENFTERVP :::::::: CCDS82 ENFTERVP 420 >>CCDS46403.1 BIN1 gene_id:274|Hs108|chr2 (439 aa) initn: 2117 init1: 1133 opt: 1138 Z-score: 604.4 bits: 121.4 E(32554): 2.4e-27 Smith-Waterman score: 2577; 74.0% identity (74.0% similar) in 593 aa overlap (1-593:1-439) 10 20 30 40 50 60 pF1KB5 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN :::::::::::::::::::::::::::::::::::: CCDS46 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 180 190 200 250 260 270 280 290 300 pF1KB5 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB5 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS :::::::::::::::::::::::::::::::::: CCDS46 DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-------------------------- 270 280 290 300 370 380 390 400 410 420 pF1KB5 LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW CCDS46 ------------------------------------------------------------ 430 440 450 460 470 480 pF1KB5 EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET ::::::::::::::::::::::: CCDS46 -------------------------------------PAEASEVAGGTQPAAGAQEPGET 310 320 490 500 510 520 530 540 pF1KB5 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 330 340 350 360 370 380 550 560 570 580 590 pF1KB5 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 390 400 410 420 430 593 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:35:50 2016 done: Sat Nov 5 21:35:51 2016 Total Scan time: 3.090 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]