FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5397, 309 aa 1>>>pF1KB5397 309 - 309 aa - 309 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6546+/-0.000339; mu= 19.4465+/- 0.021 mean_var=60.9182+/-12.243, 0's: 0 Z-trim(114.5): 28 B-trim: 898 in 1/54 Lambda= 0.164324 statistics sampled from 24428 (24452) to 24428 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.287), width: 16 Scan time: 7.420 The best scores are: opt bits E(85289) NP_078895 (OMIM: 611683) ketosamine-3-kinase [Homo ( 309) 2112 508.9 5.1e-144 NP_071441 (OMIM: 608425) fructosamine-3-kinase [Ho ( 309) 1409 342.3 7.5e-94 >>NP_078895 (OMIM: 611683) ketosamine-3-kinase [Homo sap (309 aa) initn: 2112 init1: 2112 opt: 2112 Z-score: 2706.6 bits: 508.9 E(85289): 5.1e-144 Smith-Waterman score: 2112; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309) 10 20 30 40 50 60 pF1KB5 MEELLRRELGCSSVRATGHSGGGCISQGRSYDTDQGRVFVKVNPKAEARRMFEGEMASLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MEELLRRELGCSSVRATGHSGGGCISQGRSYDTDQGRVFVKVNPKAEARRMFEGEMASLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AILKTNTVKVPKPIKVLDAPGGGSVLVMEHMDMRHLSSHAAKLGAQLADLHLDNKKLGEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 AILKTNTVKVPKPIKVLDAPGGGSVLVMEHMDMRHLSSHAAKLGAQLADLHLDNKKLGEM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RLKEAGTVGRGGGQEERPFVARFGFDVVTCCGYLPQVNDWQEDWVVFYARQRIQPQMDMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 RLKEAGTVGRGGGQEERPFVARFGFDVVTCCGYLPQVNDWQEDWVVFYARQRIQPQMDMV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EKESGDREALQLWSALQLKIPDLFRDLEIIPALLHGDLWGGNVAEDSSGPVIFDPASFYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 EKESGDREALQLWSALQLKIPDLFRDLEIIPALLHGDLWGGNVAEDSSGPVIFDPASFYG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 HSEYELAIAGMFGGFSSSFYSAYHGKIPKAPGFEKRLQLYQLFHYLNHWNHFGSGYRGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 HSEYELAIAGMFGGFSSSFYSAYHGKIPKAPGFEKRLQLYQLFHYLNHWNHFGSGYRGSS 250 260 270 280 290 300 pF1KB5 LNIMRNLVK ::::::::: NP_078 LNIMRNLVK >>NP_071441 (OMIM: 608425) fructosamine-3-kinase [Homo s (309 aa) initn: 1451 init1: 1409 opt: 1409 Z-score: 1805.9 bits: 342.3 E(85289): 7.5e-94 Smith-Waterman score: 1409; 64.4% identity (84.5% similar) in 309 aa overlap (1-309:1-309) 10 20 30 40 50 60 pF1KB5 MEELLRRELGCSSVRATGHSGGGCISQGRSYDTDQGRVFVKVNPKAEARRMFEGEMASLT ::.::: :: ...:: : :.::::.::.:::: : :::::: ...::.:::::.::: NP_071 MEQLLRAELRTATLRAFGGPGAGCISEGRAYDTDAGPVFVKVNRRTQARQMFEGEVASLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 AILKTNTVKVPKPIKVLDAPGGGSVLVMEHMDMRHLSSHAAKLGAQLADLHLDNKKLGEM :. .:. :.::.:.::.: ::::...::::. :. :::.:.::: :.::::: :.:: : NP_071 ALRSTGLVRVPRPMKVIDLPGGGAAFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RLKEAGTVGRGGGQEERPFVARFGFDVVTCCGYLPQVNDWQEDWVVFYARQRIQPQMDMV .: .:::: : : .: .::: .:::::..::::.::.:: .:.::.:.: :.:.. NP_071 LKEEENTVGRRGEGAEPQYVDKFGFHTVTCCGFIPQVNEWQDDWPTFFARHRLQAQLDLI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EKESGDREALQLWSALQLKIPDLFRDLEIIPALLHGDLWGGNVAEDSSGPVIFDPASFYG ::. .:::: .::: ::.:::::: :::.:::::::::.::::::. ::.:.::::::: NP_071 EKDYADREARELWSRLQVKIPDLFCGLEIVPALLHGDLWSGNVAEDDVGPIIYDPASFYG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 HSEYELAIAGMFGGFSSSFYSAYHGKIPKAPGFEKRLQLYQLFHYLNHWNHFGSGYRGSS :::.::::: ::::: ::..::: ::::::::..:: :::::.::::::::: ::. : NP_071 HSEFELAIALMFGGFPRSFFTAYHRKIPKAPGFDQRLLLYQLFNYLNHWNHFGREYRSPS 250 260 270 280 290 300 pF1KB5 LNIMRNLVK :. :: :.: NP_071 LGTMRRLLK 309 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:31:11 2016 done: Thu Nov 3 22:31:12 2016 Total Scan time: 7.420 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]