FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5398, 181 aa 1>>>pF1KB5398 181 - 181 aa - 181 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0483+/-0.000448; mu= 14.7587+/- 0.028 mean_var=94.1845+/-21.209, 0's: 0 Z-trim(111.5): 246 B-trim: 1253 in 2/51 Lambda= 0.132155 statistics sampled from 19789 (20179) to 19789 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.237), width: 16 Scan time: 5.290 The best scores are: opt bits E(85289) NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 1194 237.7 7.6e-63 NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 1194 237.7 7.6e-63 NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 1194 237.7 7.6e-63 NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 1194 237.7 7.6e-63 NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 1153 229.9 1.7e-60 XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 1153 229.9 1.7e-60 NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 975 196.0 2.8e-50 NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 972 195.4 4.2e-50 NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 856 173.3 1.9e-43 XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 828 168.0 8.5e-42 XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 800 162.5 2.6e-40 NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 723 147.9 8.2e-36 XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 699 143.7 3.3e-34 NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 699 143.9 4.2e-34 NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 611 126.6 2.2e-29 NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 607 125.8 3.7e-29 XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 611 127.1 4.7e-29 NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 611 127.1 4.7e-29 NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 582 121.6 2.1e-27 NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 553 115.5 4.7e-26 NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 545 114.0 1.4e-25 XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 536 112.3 4.4e-25 NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 536 112.3 4.4e-25 NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 523 109.8 2.6e-24 NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 523 109.9 2.6e-24 NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 500 105.3 4.2e-23 NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 498 105.1 7.1e-23 NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 498 105.1 7.1e-23 NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 498 105.1 7.1e-23 NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 498 105.1 7.1e-23 XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 488 103.0 2.1e-22 NP_817114 (OMIM: 608960) ADP-ribosylation factor-l ( 142) 486 102.6 2.8e-22 NP_001032251 (OMIM: 608960) ADP-ribosylation facto ( 142) 486 102.6 2.8e-22 NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 470 99.8 2.9e-21 XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 470 99.8 2.9e-21 NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 468 99.3 3.6e-21 XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 468 99.3 3.6e-21 NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 468 99.3 3.6e-21 NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 468 99.3 3.6e-21 NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 455 96.9 2e-20 NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 442 94.4 1.2e-19 XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 442 94.4 1.2e-19 NP_060654 (OMIM: 616596) ADP-ribosylation factor-l ( 186) 402 86.8 2.2e-17 NP_620150 (OMIM: 616597) ADP-ribosylation factor-l ( 186) 391 84.7 9.4e-17 XP_016862801 (OMIM: 209900,268000,600151,608845,61 ( 159) 384 83.2 2.1e-16 NP_001310443 (OMIM: 209900,268000,600151,608845,61 ( 159) 384 83.2 2.1e-16 NP_001186674 (OMIM: 601175) ADP-ribosylation facto ( 157) 366 79.8 2.3e-15 XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 367 80.1 2.4e-15 NP_003215 (OMIM: 604699) ADP-ribosylation factor-r ( 201) 367 80.1 2.4e-15 XP_011526785 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 367 80.1 2.4e-15 >>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa) initn: 1194 init1: 1194 opt: 1194 Z-score: 1249.3 bits: 237.7 E(85289): 7.6e-63 Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB5 K : NP_001 K >>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 1194 init1: 1194 opt: 1194 Z-score: 1249.3 bits: 237.7 E(85289): 7.6e-63 Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB5 K : NP_001 K >>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 1194 init1: 1194 opt: 1194 Z-score: 1249.3 bits: 237.7 E(85289): 7.6e-63 Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB5 K : NP_001 K >>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 1194 init1: 1194 opt: 1194 Z-score: 1249.3 bits: 237.7 E(85289): 7.6e-63 Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB5 K : NP_001 K >>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa) initn: 1153 init1: 1153 opt: 1153 Z-score: 1207.1 bits: 229.9 E(85289): 1.7e-60 Smith-Waterman score: 1153; 96.1% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::.::.:.:.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::.:. NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 pF1KB5 K : NP_001 K >>XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosylatio (181 aa) initn: 1153 init1: 1153 opt: 1153 Z-score: 1207.1 bits: 229.9 E(85289): 1.7e-60 Smith-Waterman score: 1153; 96.1% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::.::.:.:.::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::.:. XP_005 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 pF1KB5 K : XP_005 K >>NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 [Ho (180 aa) initn: 975 init1: 975 opt: 975 Z-score: 1023.7 bits: 196.0 E(85289): 2.8e-50 Smith-Waterman score: 975; 81.9% identity (94.4% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...::. :::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: NP_001 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::::.: NP_001 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR 130 140 150 160 170 180 pF1KB5 K >>NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 [Ho (180 aa) initn: 972 init1: 972 opt: 972 Z-score: 1020.6 bits: 195.4 E(85289): 4.2e-50 Smith-Waterman score: 972; 81.9% identity (93.2% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . ::. .::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: NP_001 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ :::::::::.:::: ..:.::::::. :: :.::.::::::.: :::.::::::..: NP_001 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR 130 140 150 160 170 180 pF1KB5 K >>NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 [Ho (175 aa) initn: 876 init1: 851 opt: 856 Z-score: 901.2 bits: 173.3 E(85289): 1.9e-43 Smith-Waterman score: 856; 67.6% identity (88.3% similar) in 179 aa overlap (1-179:1-175) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN ::..... .::.:::::::.:::::::::::::::::. ::::::.::::::: ::: NP_001 MGKVLSK----IFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKN 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV ..:.:::::::::::::::::. .::::::::: ::.:..:::.:: :.. . :.:::. NP_001 VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ .:.::::::::.::. :: .:::: .: ::::.: .:::::::::::: ::... .. NP_001 ILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 120 130 140 150 160 170 pF1KB5 K >>XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosylatio (212 aa) initn: 828 init1: 828 opt: 828 Z-score: 871.3 bits: 168.0 E(85289): 8.5e-42 Smith-Waterman score: 828; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KB5 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ :::::::: XP_016 LLVFANKQVGARASLGNVRSQCGFRLVVGVTGGWWGPFLCPVDSPSHQPFLPPGPPQRHE 130 140 150 160 170 180 181 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:18:46 2016 done: Thu Nov 3 17:18:47 2016 Total Scan time: 5.290 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]