FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5399, 191 aa 1>>>pF1KB5399 191 - 191 aa - 191 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1743+/-0.000991; mu= 14.0987+/- 0.060 mean_var=81.8324+/-16.145, 0's: 0 Z-trim(105.6): 93 B-trim: 4 in 1/50 Lambda= 0.141779 statistics sampled from 8422 (8529) to 8422 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.262), width: 16 Scan time: 1.820 The best scores are: opt bits E(32554) CCDS1689.1 VSNL1 gene_id:7447|Hs108|chr2 ( 191) 1277 270.7 3.9e-73 CCDS441.1 HPCAL4 gene_id:51440|Hs108|chr1 ( 191) 1181 251.0 3.2e-67 CCDS6292.1 NCALD gene_id:83988|Hs108|chr8 ( 193) 926 198.9 1.6e-51 CCDS1671.1 HPCAL1 gene_id:3241|Hs108|chr2 ( 193) 919 197.5 4.4e-51 CCDS370.1 HPCA gene_id:3208|Hs108|chr1 ( 193) 892 191.9 2e-49 CCDS6932.1 NCS1 gene_id:23413|Hs108|chr9 ( 190) 763 165.5 1.7e-41 CCDS78448.1 NCS1 gene_id:23413|Hs108|chr9 ( 172) 671 146.7 7.5e-36 CCDS11151.1 RCVRN gene_id:5957|Hs108|chr17 ( 200) 615 135.3 2.3e-32 CCDS64313.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 188) 567 125.4 2e-29 CCDS4374.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 216) 567 125.5 2.2e-29 CCDS34285.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 225) 567 125.5 2.3e-29 CCDS34286.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 227) 567 125.5 2.3e-29 CCDS47035.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 188) 554 122.8 1.3e-28 CCDS43215.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 216) 554 122.8 1.4e-28 CCDS43217.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 225) 554 122.9 1.5e-28 CCDS3428.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 229) 554 122.9 1.5e-28 CCDS43216.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 250) 554 122.9 1.6e-28 CCDS7524.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 220) 552 122.4 1.9e-28 CCDS7525.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 225) 552 122.4 1.9e-28 CCDS41562.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 252) 552 122.5 2.1e-28 CCDS7522.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 270) 552 122.5 2.2e-28 CCDS7521.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 285) 552 122.5 2.3e-28 CCDS7523.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 227) 534 118.8 2.5e-27 CCDS33245.1 KCNIP3 gene_id:30818|Hs108|chr2 ( 230) 525 116.9 9e-27 CCDS2013.1 KCNIP3 gene_id:30818|Hs108|chr2 ( 256) 525 117.0 9.7e-27 CCDS4865.1 GUCA1B gene_id:2979|Hs108|chr6 ( 200) 502 112.2 2.1e-25 CCDS4864.1 GUCA1A gene_id:2978|Hs108|chr6 ( 201) 427 96.8 8.8e-21 CCDS64312.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 241) 412 93.8 8.5e-20 CCDS72761.1 HPCAL4 gene_id:51440|Hs108|chr1 ( 119) 402 91.5 2.1e-19 CCDS2954.1 GUCA1C gene_id:9626|Hs108|chr3 ( 209) 340 79.1 2.1e-15 >>CCDS1689.1 VSNL1 gene_id:7447|Hs108|chr2 (191 aa) initn: 1277 init1: 1277 opt: 1277 Z-score: 1426.5 bits: 270.7 E(32554): 3.9e-73 Smith-Waterman score: 1277; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS 130 140 150 160 170 180 190 pF1KB5 IVLLLQCDIQK ::::::::::: CCDS16 IVLLLQCDIQK 190 >>CCDS441.1 HPCAL4 gene_id:51440|Hs108|chr1 (191 aa) initn: 1181 init1: 1181 opt: 1181 Z-score: 1320.3 bits: 251.0 E(32554): 3.2e-67 Smith-Waterman score: 1181; 89.5% identity (99.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD ::: ::::::::.::::..:::.:.:::::::::::::::: ::::::::::.::::::: CCDS44 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE ::::::::::::::::::::::::::::::.::::::::::::::.::::::::.:::.: CCDS44 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS ::::::::::::::::::.::.:::::.:::::::.:::..:::::::.::::::::::: CCDS44 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS 130 140 150 160 170 180 190 pF1KB5 IVLLLQCDIQK ::::::::.:: CCDS44 IVLLLQCDMQK 190 >>CCDS6292.1 NCALD gene_id:83988|Hs108|chr8 (193 aa) initn: 749 init1: 735 opt: 926 Z-score: 1038.4 bits: 198.9 E(32554): 1.6e-51 Smith-Waterman score: 926; 69.7% identity (92.0% similar) in 188 aa overlap (1-188:1-186) 10 20 30 40 50 60 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD :::::::: ::::.::..::.:.:::...::::::.:::::.:..:::...: .:::::: CCDS62 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE :::::.:.::::: :::::::::::: :::.::::..::::.:::.::::::.: :...: CCDS62 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS ::::..::::::..: ::: :: :::.:..::: .:: :.: ...:.:: ..:::::: CCDS62 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPS 130 140 150 160 170 190 pF1KB5 IVLLLQCDIQK :: ::::: CCDS62 IVRLLQCDPSSAGQF 180 190 >>CCDS1671.1 HPCAL1 gene_id:3241|Hs108|chr2 (193 aa) initn: 725 init1: 725 opt: 919 Z-score: 1030.7 bits: 197.5 E(32554): 4.4e-51 Smith-Waterman score: 919; 69.7% identity (91.5% similar) in 188 aa overlap (1-188:1-186) 10 20 30 40 50 60 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD :::::::: :::..:: ..:::..:::..::::::::::.:.:...::...:..:::::: CCDS16 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE :::::.:.::::: :::::::::::: :::.::::..::::.:::.::::::.: :.: : CCDS16 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS ::::..::::::..: ::: :: :::.:.:::: .:: :.: ...:.:: ..:::::: CCDS16 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPS 130 140 150 160 170 190 pF1KB5 IVLLLQCDIQK :: ::::: CCDS16 IVRLLQCDPSSASQF 180 190 >>CCDS370.1 HPCA gene_id:3208|Hs108|chr1 (193 aa) initn: 704 init1: 704 opt: 892 Z-score: 1000.8 bits: 191.9 E(32554): 2e-49 Smith-Waterman score: 892; 68.6% identity (89.4% similar) in 188 aa overlap (1-188:1-186) 10 20 30 40 50 60 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD :::::::: ::...:: ..:::.: ::..::::::::::.: ::..::...:..:::::: CCDS37 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE :::::.:.::::: :.:::::::::: :::.:::: .:::: :::.::::::.: :.: : CCDS37 ASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS ::::..::::::..: ::: :: :::.:..::: .:: :.: ...:.:: ..:::::: CCDS37 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPS 130 140 150 160 170 190 pF1KB5 IVLLLQCDIQK :: ::::: CCDS37 IVRLLQCDPSSASQF 180 190 >>CCDS6932.1 NCS1 gene_id:23413|Hs108|chr9 (190 aa) initn: 817 init1: 607 opt: 763 Z-score: 858.3 bits: 165.5 E(32554): 1.7e-41 Smith-Waterman score: 763; 58.4% identity (85.4% similar) in 185 aa overlap (1-185:1-183) 10 20 30 40 50 60 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD :::.:::: :::.:.:...: :.:.:..::::::.::::::.:. ::..: .:::.:: CCDS69 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE .::: .: .::.: :: :.: ::: :::.::::....:: :::..::::.:: ::: : CCDS69 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS ::.:..:::.:::... . .:. :::.:::.::. :::: : ..::.::.:..:.::: CCDS69 MLDIVDAIYQMVGNTVELPEEEN--TPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPS 130 140 150 160 170 190 pF1KB5 IVLLLQCDIQK :: : CCDS69 IVQALSLYDGLV 180 190 >>CCDS78448.1 NCS1 gene_id:23413|Hs108|chr9 (172 aa) initn: 710 init1: 500 opt: 671 Z-score: 757.2 bits: 146.7 E(32554): 7.5e-36 Smith-Waterman score: 671; 58.0% identity (84.6% similar) in 162 aa overlap (24-185:6-165) 10 20 30 40 50 60 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD :.:..::::::.::::::.:. ::..: .:::.:: CCDS78 MATITEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 10 20 30 40 70 80 90 100 110 120 pF1KB5 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE .::: .: .::.: :: :.: ::: :::.::::....:: :::..::::.:: ::: : CCDS78 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS ::.:..:::.:::... . .:. :::.:::.::. :::: : ..::.::.:..:.::: CCDS78 MLDIVDAIYQMVGNTVELPEEEN--TPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPS 110 120 130 140 150 160 190 pF1KB5 IVLLLQCDIQK :: : CCDS78 IVQALSLYDGLV 170 >>CCDS11151.1 RCVRN gene_id:5957|Hs108|chr17 (200 aa) initn: 583 init1: 583 opt: 615 Z-score: 694.4 bits: 135.3 E(32554): 2.3e-32 Smith-Waterman score: 615; 45.8% identity (79.2% similar) in 192 aa overlap (1-191:1-192) 10 20 30 40 50 pF1KB5 MGKQNS-KLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYG ::...: :. :..:.: .:.:.:.:: .::..::::::.::.. ..::..:.:::: CCDS11 MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRV : . .:::.::.::.: :::.::.:.. :: .:. :. .:::.:::..::.::.: :.. CCDS11 DPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 EMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDP :.:::. ::.::. . . .: :::.:..::.. . :: ::..: :: :.. .. CCDS11 EVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANK 130 140 150 160 170 180 180 190 pF1KB5 SIVLLLQCDIQK :. :.: . :: CCDS11 EILRLIQFEPQKVKEKMKNA 190 200 >>CCDS64313.1 KCNIP1 gene_id:30820|Hs108|chr5 (188 aa) initn: 567 init1: 437 opt: 567 Z-score: 641.7 bits: 125.4 E(32554): 2e-29 Smith-Waterman score: 567; 46.3% identity (76.8% similar) in 177 aa overlap (10-186:8-182) 10 20 30 40 50 60 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD :: .:.: .:.:...::. :.:: ..:::: .: . :.:.:..:::.:: CCDS64 MTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEDTFKQIYAQFFPHGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE :: .:.. : .:: . :.. :..:. :::: ::. ..:: :.::.::.. :: :.. : CCDS64 ASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS :..:..::: :.: . ..:: ::.:.:: .:.::::::: .::::: :. . : . CCDS64 MMDIVKAIYDMMGKYTYPVLKED--TPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDN 120 130 140 150 160 170 190 pF1KB5 IVLLLQCDIQK :. :: CCDS64 IMRSLQLFQNVM 180 >>CCDS4374.1 KCNIP1 gene_id:30820|Hs108|chr5 (216 aa) initn: 567 init1: 437 opt: 567 Z-score: 640.9 bits: 125.5 E(32554): 2.2e-29 Smith-Waterman score: 567; 46.3% identity (76.8% similar) in 177 aa overlap (10-186:36-210) 10 20 30 pF1KB5 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCP :: .:.: .:.:...::. :.:: ..:: CCDS43 GTFSSLQTKQRRPSKDKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 SGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQ :: .: . :.:.:..:::.:::: .:.. : .:: . :.. :..:. :::: ::. .. CCDS43 SGVVNEDTFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 KLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMD :: :.::.::.. :: :.. ::..:..::: :.: . ..:: ::.:.:: .:.::: CCDS43 KLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKED--TPRQHVDVFFQKMD 130 140 150 160 170 180 160 170 180 190 pF1KB5 KNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK :::: .::::: :. . : .:. :: CCDS43 KNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM 190 200 210 191 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:33:32 2016 done: Sat Nov 5 12:33:33 2016 Total Scan time: 1.820 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]