FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5400, 471 aa 1>>>pF1KB5400 471 - 471 aa - 471 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3535+/-0.000965; mu= 4.8904+/- 0.059 mean_var=374.7849+/-76.883, 0's: 0 Z-trim(116.0): 26 B-trim: 20 in 1/54 Lambda= 0.066250 statistics sampled from 16602 (16626) to 16602 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.511), width: 16 Scan time: 3.620 The best scores are: opt bits E(32554) CCDS14410.1 NONO gene_id:4841|Hs108|chrX ( 471) 3200 319.4 5e-87 CCDS55445.1 NONO gene_id:4841|Hs108|chrX ( 382) 2567 258.8 7.1e-69 CCDS41870.1 PSPC1 gene_id:55269|Hs108|chr13 ( 523) 1773 183.1 6.1e-46 CCDS388.1 SFPQ gene_id:6421|Hs108|chr1 ( 707) 1716 177.8 3.2e-44 >>CCDS14410.1 NONO gene_id:4841|Hs108|chrX (471 aa) initn: 3200 init1: 3200 opt: 3200 Z-score: 1675.9 bits: 319.4 E(32554): 5e-87 Smith-Waterman score: 3200; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 EAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 EMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATMM 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY 430 440 450 460 470 >>CCDS55445.1 NONO gene_id:4841|Hs108|chrX (382 aa) initn: 2567 init1: 2567 opt: 2567 Z-score: 1350.0 bits: 258.8 E(32554): 7.1e-69 Smith-Waterman score: 2567; 100.0% identity (100.0% similar) in 382 aa overlap (90-471:1-382) 60 70 80 90 100 110 pF1KB5 KNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETR :::::::::::::::::::::::::::::: CCDS55 MRKLFEKYGKAGEVFIHKDKGFGFIRLETR 10 20 30 120 130 140 150 160 170 pF1KB5 TLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVV 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 IVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 IVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEK 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 LVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEME 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB5 MEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQ 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB5 EEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPAGTPAPPGPATM 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB5 MPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGAEFAPNKRRRY 340 350 360 370 380 >>CCDS41870.1 PSPC1 gene_id:55269|Hs108|chr13 (523 aa) initn: 1767 init1: 1594 opt: 1773 Z-score: 938.3 bits: 183.1 E(32554): 6.1e-46 Smith-Waterman score: 1780; 60.0% identity (79.1% similar) in 468 aa overlap (37-460:45-511) 10 20 30 40 50 60 pF1KB5 FNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPG : :: :: .. ... :.:::.:.: ::: CCDS41 NPARLRALESAVGESEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPG 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB5 EKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAK :::.::: :::::::: :::::....:::.::. .::::..:.::::::::.:::::::: CCDS41 EKTYTQRCRLFVGNLPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAK 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB5 VELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGR .:::. :... ::.::: :.:.:::.:: :::::::.::: :: ::.:::.:::::: CCDS41 AELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDRGR 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB5 PSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQ .:::.:::..:: :::::.::..:.::::: :::: ::::.:.:::.::::::. :.:: CCDS41 ATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQ 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB5 FHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHE .::::::::::::::.::.::: ::::: ::::::..::::::.::.:::: :::::::: CCDS41 YHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEKLEAEMEAARHE 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB5 HQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM-RRQQEEMMRR ::.::::::::::::::::.:::.:::.:::::..::.:::.::::::: :....: .:: CCDS41 HQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEELRR 320 330 340 350 360 370 370 380 390 400 pF1KB5 QQEGFKGTFPDAREQEIRMGQMA------MGGA----------------MGINNRGAMPP :::::: .. . ::::.:::.:. :: : :..:::...: CCDS41 QQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMNMNNRATIPG 380 390 400 410 420 430 410 420 430 440 pF1KB5 APVPAGTPA--PPGPATM----MPDG------TLGLTPPTT------ERFGQA---ATME :. : :: : : :.: :::. . ::. : :. : : CCDS41 PPMGPG-PAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMGSRTGSETPQAPMS 440 450 460 470 480 490 450 460 470 pF1KB5 GIGAIGGTPPAFNRAAPGAEFAPNKRRRY :.: ..: : .:.:.. : CCDS41 GVGPVSGGPGGFGRGSQGGNFEGPNKRRRY 500 510 520 >>CCDS388.1 SFPQ gene_id:6421|Hs108|chr1 (707 aa) initn: 1765 init1: 1622 opt: 1716 Z-score: 907.4 bits: 177.8 E(32554): 3.2e-44 Smith-Waterman score: 1778; 60.0% identity (79.9% similar) in 473 aa overlap (16-471:241-707) 10 20 30 40 pF1KB5 MQSNKTFNLEKQNHTPRKHHQHHHQQQHHQQQQQQPPPPPIPANG :: .::: .:::..: ::: . . CCDS38 KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH--PPYHQQHHQGPPPGGPGGRS 220 230 240 250 260 50 60 70 80 90 100 pF1KB5 QQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFI .. :..::. .:. .:.:::::.::: :::::::: ::::.:...:: :::. ::::: CCDS38 EEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFI 270 280 290 300 310 320 110 120 130 140 150 160 pF1KB5 HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLE .: ::::::.::.:.::::::.:::. :.::.::::::: :.:.:.:::: :::::::: CCDS38 NKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLE 330 340 350 360 370 380 170 180 190 200 210 220 pF1KB5 EAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVE :::: :: .:::::::::::: .:::::::..:::::::..::::: ::::: :::: :: CCDS38 EAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVE 390 400 410 420 430 440 230 240 250 260 270 280 pF1KB5 PMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQV :..:::::.::::::. :: ...:::: :::::: :.:::::..:::.: ::::::..:: CCDS38 PLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQV 450 460 470 480 490 500 290 300 310 320 330 340 pF1KB5 DRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQE ..:.:.:..::: ::: : ::::. :.:::::::::::::::::::::.::::...:::: CCDS38 EKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQE 510 520 530 540 550 560 350 360 370 380 390 pF1KB5 EERRRREEEM---RRQQEEMMRRQ-QEGF-KGTFPDAREQEIRMG---QMAMGGAMGINN :::::::::: .:..::.:::: .:.. . . : ::...::: : :: .: .. CCDS38 EERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGGGGAMNMGDPYGSGG 570 580 590 600 610 620 400 410 420 430 440 pF1KB5 RGAMPPAPVPAGT--PAPPG--PATMMPDGTLGLTPPTTERFGQ--AATMEGIGAIG--- . .:: .: : :: :::: .:.. . :::::: :. . : : : CCDS38 Q-KFPPLGGGGGIGYEANPGVPPATM--SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGP 630 640 650 660 670 680 450 460 470 pF1KB5 GTPPAFNRAAPGAEFAPNKRRRY ::: ...:. : .:::. :. CCDS38 GTPAGYGRGREEYE-GPNKKPRF 690 700 471 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:42:57 2016 done: Fri Nov 4 03:42:58 2016 Total Scan time: 3.620 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]