FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5403, 913 aa 1>>>pF1KB5403 913 - 913 aa - 913 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3480+/-0.00133; mu= 2.7948+/- 0.080 mean_var=236.6573+/-46.730, 0's: 0 Z-trim(108.0): 46 B-trim: 0 in 0/51 Lambda= 0.083371 statistics sampled from 9899 (9928) to 9899 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.305), width: 16 Scan time: 4.320 The best scores are: opt bits E(32554) CCDS10638.1 EIF3C gene_id:8663|Hs108|chr16 ( 913) 5994 735.2 1.3e-211 CCDS42136.1 EIF3CL gene_id:728689|Hs108|chr16 ( 914) 5982 733.7 3.6e-211 CCDS66993.1 EIF3C gene_id:8663|Hs108|chr16 ( 903) 5175 636.7 6e-182 >>CCDS10638.1 EIF3C gene_id:8663|Hs108|chr16 (913 aa) initn: 5994 init1: 5994 opt: 5994 Z-score: 3912.4 bits: 735.2 E(32554): 1.3e-211 Smith-Waterman score: 5994; 100.0% identity (100.0% similar) in 913 aa overlap (1-913:1-913) 10 20 30 40 50 60 pF1KB5 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR 850 860 870 880 890 900 910 pF1KB5 RGGYRQQQSQTAY ::::::::::::: CCDS10 RGGYRQQQSQTAY 910 >>CCDS42136.1 EIF3CL gene_id:728689|Hs108|chr16 (914 aa) initn: 4188 init1: 4188 opt: 5982 Z-score: 3904.6 bits: 733.7 E(32554): 3.6e-211 Smith-Waterman score: 5982; 99.9% identity (99.9% similar) in 914 aa overlap (1-913:1-914) 10 20 30 40 50 60 pF1KB5 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE-DNEGG :::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::: CCDS42 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEEDNEGG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 EWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 IAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 VGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB5 CAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 CAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAEN 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB5 EGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQ 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB5 HADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 HADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERN 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB5 QEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB5 VGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTML 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB5 VRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VRKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB5 QTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYM 850 860 870 880 890 900 900 910 pF1KB5 RRGGYRQQQSQTAY :::::::::::::: CCDS42 RRGGYRQQQSQTAY 910 >>CCDS66993.1 EIF3C gene_id:8663|Hs108|chr16 (903 aa) initn: 5172 init1: 5172 opt: 5175 Z-score: 3380.0 bits: 636.7 E(32554): 6e-182 Smith-Waterman score: 5892; 98.9% identity (98.9% similar) in 913 aa overlap (1-913:1-903) 10 20 30 40 50 60 pF1KB5 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MSRFFTTGSDSESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNEL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNE- 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 WEDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 ---------MNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 SSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 DSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 WERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQI 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 AAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVC 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 AIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKAHQRQLTPPEGSSKSEQDQAENE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB5 GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQH 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB5 ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 ADPPVQILYNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQ 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB5 EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 EQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRV 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB5 GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLV 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB5 RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 RKIQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQ 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB5 TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQGTYGGYFRDQKDGYRKNEGYMR 840 850 860 870 880 890 910 pF1KB5 RGGYRQQQSQTAY ::::::::::::: CCDS66 RGGYRQQQSQTAY 900 913 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:13:00 2016 done: Sat Nov 5 00:13:01 2016 Total Scan time: 4.320 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]