Result of FASTA (ccds) for
pF1KB5406
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5406, 331 aa
1>>>pF1KB5406 331 - 331 aa - 331 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1978+/-0.00105; mu= 15.9532+/- 0.063
mean_var=52.0163+/-10.057, 0's: 0 Z-trim(100.9): 31 B-trim: 0 in 0/48
Lambda= 0.177830
statistics sampled from 6295 (6306) to 6295 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.194), width: 16
Scan time: 2.340
The best scores are: opt bits E(32554)
CCDS8777.1 PRKAG1 gene_id:5571|Hs108|chr12 ( 331) 2112 550.0 1e-156
CCDS55824.1 PRKAG1 gene_id:5571|Hs108|chr12 ( 299) 1908 497.6 5.2e-141
CCDS55825.1 PRKAG1 gene_id:5571|Hs108|chr12 ( 340) 1576 412.4 2.5e-115
CCDS47752.1 PRKAG2 gene_id:51422|Hs108|chr7 ( 328) 1555 407.1 1e-113
CCDS43683.1 PRKAG2 gene_id:51422|Hs108|chr7 ( 525) 1555 407.1 1.6e-113
CCDS5928.1 PRKAG2 gene_id:51422|Hs108|chr7 ( 569) 1555 407.1 1.7e-113
CCDS2424.1 PRKAG3 gene_id:53632|Hs108|chr2 ( 489) 1302 342.2 5.2e-94
>>CCDS8777.1 PRKAG1 gene_id:5571|Hs108|chr12 (331 aa)
initn: 2112 init1: 2112 opt: 2112 Z-score: 2927.2 bits: 550.0 E(32554): 1e-156
Smith-Waterman score: 2112; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331)
10 20 30 40 50 60
pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS87 YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL
250 260 270 280 290 300
310 320 330
pF1KB5 VVVDENDVVKGIVSLSDILQALVLTGGEKKP
:::::::::::::::::::::::::::::::
CCDS87 VVVDENDVVKGIVSLSDILQALVLTGGEKKP
310 320 330
>>CCDS55824.1 PRKAG1 gene_id:5571|Hs108|chr12 (299 aa)
initn: 1908 init1: 1908 opt: 1908 Z-score: 2645.1 bits: 497.6 E(32554): 5.2e-141
Smith-Waterman score: 1908; 100.0% identity (100.0% similar) in 299 aa overlap (33-331:1-299)
10 20 30 40 50 60
pF1KB5 TVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFF
::::::::::::::::::::::::::::::
CCDS55 MKSHRCYDLIPTSSKLVVFDTSLQVKKAFF
10 20 30
70 80 90 100 110 120
pF1KB5 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 QDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 FPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 FPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 KFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVV
220 230 240 250 260 270
310 320 330
pF1KB5 VDENDVVKGIVSLSDILQALVLTGGEKKP
:::::::::::::::::::::::::::::
CCDS55 VDENDVVKGIVSLSDILQALVLTGGEKKP
280 290
>>CCDS55825.1 PRKAG1 gene_id:5571|Hs108|chr12 (340 aa)
initn: 1576 init1: 1576 opt: 1576 Z-score: 2183.8 bits: 412.4 E(32554): 2.5e-115
Smith-Waterman score: 2084; 97.4% identity (97.4% similar) in 340 aa overlap (1-331:1-340)
10 20 30 40 50 60
pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 FFALVTNGVRAAPLWDSKKQSFV---------GMLTITDFINILHRYYKSALVQIYELEE
::::::::::::::::::::::: ::::::::::::::::::::::::::::
CCDS55 FFALVTNGVRAAPLWDSKKQSFVVLRALSCPLGMLTITDFINILHRYYKSALVQIYELEE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 HKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 ILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 DEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINR
250 260 270 280 290 300
300 310 320 330
pF1KB5 LVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP
::::::::::::::::::::::::::::::::::::::::
CCDS55 LVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP
310 320 330 340
>>CCDS47752.1 PRKAG2 gene_id:51422|Hs108|chr7 (328 aa)
initn: 1552 init1: 1552 opt: 1555 Z-score: 2155.0 bits: 407.1 E(32554): 1e-113
Smith-Waterman score: 1555; 76.1% identity (92.9% similar) in 309 aa overlap (23-330:14-322)
10 20 30 40 50 60
pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA
.:...:: ::.::.:::..:::::::::::.::::::
CCDS47 MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKA
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV
:::::.:::::::::.::::::::::::::::::::::::: .::::::::::::::::.
CCDS47 FFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWREL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI
:::..::::: :::.::::::: :::.::::::::::: :::.:::::::::::::.::.
CCDS47 YLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI
...::: ::...:.:: :::: :::... ::. ::.:::..:.::::::::.:.::::
CCDS47 SDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL
:::::::::::::::::::..::.::::::.:::::.:: : ::::..:.:.::::::
CCDS47 YSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRL
240 250 260 270 280 290
310 320 330
pF1KB5 VVVDENDVVKGIVSLSDILQALVLT-GGEKKP
:::.: : . ::.:::::::::.:: .: :.
CCDS47 VVVNEADSIVGIISLSDILQALILTPAGAKQKETETE
300 310 320
>>CCDS43683.1 PRKAG2 gene_id:51422|Hs108|chr7 (525 aa)
initn: 1552 init1: 1552 opt: 1555 Z-score: 2151.6 bits: 407.1 E(32554): 1.6e-113
Smith-Waterman score: 1555; 76.1% identity (92.9% similar) in 309 aa overlap (23-330:211-519)
10 20 30 40 50
pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFD
.:...:: ::.::.:::..::::::::::
CCDS43 PSKAAALAAALGPAEAGMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFD
190 200 210 220 230 240
60 70 80 90 100 110
pF1KB5 TSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEH
:.:::::::::::.:::::::::.::::::::::::::::::::::::: .:::::::::
CCDS43 TTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEH
250 260 270 280 290 300
120 130 140 150 160 170
pF1KB5 KIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRI
:::::::.:::..::::: :::.::::::: :::.::::::::::: :::.:::::::::
CCDS43 KIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRI
310 320 330 340 350 360
180 190 200 210 220 230
pF1KB5 LKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVD
::::.::....::: ::...:.:: :::: :::... ::. ::.:::..:.:::::::
CCDS43 LKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVD
370 380 390 400 410 420
240 250 260 270 280 290
pF1KB5 EKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRL
:.:.:::::::::::::::::::::::..::.::::::.:::::.:: : ::::..:.
CCDS43 ESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRI
430 440 450 460 470 480
300 310 320 330
pF1KB5 VEAEVHRLVVVDENDVVKGIVSLSDILQALVLT-GGEKKP
:.:::::::::.: : . ::.:::::::::.:: .: :.
CCDS43 VRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE
490 500 510 520
>>CCDS5928.1 PRKAG2 gene_id:51422|Hs108|chr7 (569 aa)
initn: 1552 init1: 1552 opt: 1555 Z-score: 2151.0 bits: 407.1 E(32554): 1.7e-113
Smith-Waterman score: 1555; 76.1% identity (92.9% similar) in 309 aa overlap (23-330:255-563)
10 20 30 40 50
pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFD
.:...:: ::.::.:::..::::::::::
CCDS59 PSKAAALAAALGPAEAGMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFD
230 240 250 260 270 280
60 70 80 90 100 110
pF1KB5 TSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEH
:.:::::::::::.:::::::::.::::::::::::::::::::::::: .:::::::::
CCDS59 TTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEH
290 300 310 320 330 340
120 130 140 150 160 170
pF1KB5 KIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRI
:::::::.:::..::::: :::.::::::: :::.::::::::::: :::.:::::::::
CCDS59 KIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRI
350 360 370 380 390 400
180 190 200 210 220 230
pF1KB5 LKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVD
::::.::....::: ::...:.:: :::: :::... ::. ::.:::..:.:::::::
CCDS59 LKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVD
410 420 430 440 450 460
240 250 260 270 280 290
pF1KB5 EKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRL
:.:.:::::::::::::::::::::::..::.::::::.:::::.:: : ::::..:.
CCDS59 ESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRI
470 480 490 500 510 520
300 310 320 330
pF1KB5 VEAEVHRLVVVDENDVVKGIVSLSDILQALVLT-GGEKKP
:.:::::::::.: : . ::.:::::::::.:: .: :.
CCDS59 VRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE
530 540 550 560
>>CCDS2424.1 PRKAG3 gene_id:53632|Hs108|chr2 (489 aa)
initn: 1334 init1: 1291 opt: 1302 Z-score: 1801.3 bits: 342.2 E(32554): 5.2e-94
Smith-Waterman score: 1302; 63.4% identity (86.6% similar) in 306 aa overlap (20-325:175-480)
10 20 30 40
pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLV
: . . ..: ::. : ::: . ::::::
CCDS24 WECELEGLLEERPALCLSPQAPFPKLGWDDELRKPGAQIYMRFMQEHTCYDAMATSSKLV
150 160 170 180 190 200
50 60 70 80 90 100
pF1KB5 VFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYEL
.::: :..::::::::.:::::::::::::::::::::::::: .:::::.: ::::::.
CCDS24 IFDTMLEIKKAFFALVANGVRAAPLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEI
210 220 230 240 250 260
110 120 130 140 150 160
pF1KB5 EEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTH
:.::::::::.::: ::::: :::: :::.:: .::.:.::::::.:: :::.:.::::
CCDS24 EQHKIETWREIYLQGCFKPLVSISPNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLHILTH
270 280 290 300 310 320
170 180 190 200 210 220
pF1KB5 KRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALP
::.::::..: . .:.: :. .....: :::. ..:.: :.:. .:: :::..::::::
CCDS24 KRLLKFLHIFGSLLPRPSFLYRTIQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALP
330 340 350 360 370 380
230 240 250 260 270 280
pF1KB5 VVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETII
::.: :.:: .::.::::.:::..:::.::.:: .::..:. .::::.: ::.: .:
CCDS24 VVNECGQVVGLYSRFDVIHLAAQQTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVI
390 400 410 420 430 440
290 300 310 320 330
pF1KB5 NRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP
.:... .:::::.:::.. . :.::::::::::::.
CCDS24 DRIAREQVHRLVLVDETQHLLGVVSLSDILQALVLSPAGIDALGA
450 460 470 480
331 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:44:06 2016 done: Fri Nov 4 03:44:06 2016
Total Scan time: 2.340 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]