FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5406, 331 aa 1>>>pF1KB5406 331 - 331 aa - 331 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9763+/-0.000443; mu= 17.4632+/- 0.028 mean_var=53.6128+/-10.651, 0's: 0 Z-trim(107.5): 51 B-trim: 0 in 0/48 Lambda= 0.175162 statistics sampled from 15559 (15610) to 15559 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.545), E-opt: 0.2 (0.183), width: 16 Scan time: 6.590 The best scores are: opt bits E(85289) NP_002724 (OMIM: 602742) 5'-AMP-activated protein ( 331) 2112 542.0 6.4e-154 XP_011536864 (OMIM: 602742) PREDICTED: 5'-AMP-acti ( 299) 1908 490.5 1.9e-138 XP_006719562 (OMIM: 602742) PREDICTED: 5'-AMP-acti ( 299) 1908 490.5 1.9e-138 NP_001193639 (OMIM: 602742) 5'-AMP-activated prote ( 299) 1908 490.5 1.9e-138 XP_005269076 (OMIM: 602742) PREDICTED: 5'-AMP-acti ( 368) 1769 455.4 8.6e-128 NP_001193638 (OMIM: 602742) 5'-AMP-activated prote ( 340) 1576 406.6 3.9e-113 XP_005269077 (OMIM: 602742) PREDICTED: 5'-AMP-acti ( 247) 1567 404.2 1.4e-112 XP_016875112 (OMIM: 602742) PREDICTED: 5'-AMP-acti ( 247) 1567 404.2 1.4e-112 XP_016875111 (OMIM: 602742) PREDICTED: 5'-AMP-acti ( 247) 1567 404.2 1.4e-112 XP_016867765 (OMIM: 194200,261740,600858,602743) P ( 327) 1564 403.5 3.1e-112 NP_001291456 (OMIM: 194200,261740,600858,602743) 5 ( 444) 1564 403.6 4e-112 XP_016867761 (OMIM: 194200,261740,600858,602743) P ( 524) 1564 403.6 4.6e-112 XP_016867760 (OMIM: 194200,261740,600858,602743) P ( 524) 1564 403.6 4.6e-112 XP_016867763 (OMIM: 194200,261740,600858,602743) P ( 377) 1562 403.1 4.9e-112 XP_011514586 (OMIM: 194200,261740,600858,602743) P ( 564) 1564 403.6 4.9e-112 XP_016867758 (OMIM: 194200,261740,600858,602743) P ( 568) 1564 403.6 5e-112 XP_016867757 (OMIM: 194200,261740,600858,602743) P ( 574) 1562 403.1 7.1e-112 XP_011514584 (OMIM: 194200,261740,600858,602743) P ( 614) 1562 403.2 7.5e-112 XP_016867766 (OMIM: 194200,261740,600858,602743) P ( 320) 1555 401.3 1.5e-111 NP_001291460 (OMIM: 194200,261740,600858,602743) 5 ( 328) 1555 401.3 1.5e-111 NP_077747 (OMIM: 194200,261740,600858,602743) 5'-A ( 328) 1555 401.3 1.5e-111 XP_016867762 (OMIM: 194200,261740,600858,602743) P ( 445) 1555 401.3 1.9e-111 XP_016867759 (OMIM: 194200,261740,600858,602743) P ( 525) 1555 401.4 2.2e-111 NP_001035723 (OMIM: 194200,261740,600858,602743) 5 ( 525) 1555 401.4 2.2e-111 XP_011514588 (OMIM: 194200,261740,600858,602743) P ( 370) 1553 400.8 2.3e-111 XP_011514587 (OMIM: 194200,261740,600858,602743) P ( 378) 1553 400.8 2.4e-111 XP_011514585 (OMIM: 194200,261740,600858,602743) P ( 565) 1555 401.4 2.4e-111 NP_057287 (OMIM: 194200,261740,600858,602743) 5'-A ( 569) 1555 401.4 2.4e-111 XP_005250063 (OMIM: 194200,261740,600858,602743) P ( 495) 1553 400.8 3e-111 XP_005250061 (OMIM: 194200,261740,600858,602743) P ( 575) 1553 400.9 3.4e-111 XP_006716084 (OMIM: 194200,261740,600858,602743) P ( 615) 1553 400.9 3.7e-111 XP_005250059 (OMIM: 194200,261740,600858,602743) P ( 619) 1553 400.9 3.7e-111 XP_016867768 (OMIM: 194200,261740,600858,602743) P ( 308) 1536 396.5 3.9e-110 XP_016867769 (OMIM: 194200,261740,600858,602743) P ( 308) 1536 396.5 3.9e-110 XP_016867770 (OMIM: 194200,261740,600858,602743) P ( 308) 1536 396.5 3.9e-110 XP_016867767 (OMIM: 194200,261740,600858,602743) P ( 308) 1536 396.5 3.9e-110 XP_016867771 (OMIM: 194200,261740,600858,602743) P ( 308) 1536 396.5 3.9e-110 XP_011514589 (OMIM: 194200,261740,600858,602743) P ( 358) 1534 396.0 6.4e-110 XP_016867764 (OMIM: 194200,261740,600858,602743) P ( 358) 1534 396.0 6.4e-110 XP_016859832 (OMIM: 604976) PREDICTED: 5'-AMP-acti ( 489) 1302 337.4 3.7e-92 NP_059127 (OMIM: 604976) 5'-AMP-activated protein ( 489) 1302 337.4 3.7e-92 >>NP_002724 (OMIM: 602742) 5'-AMP-activated protein kina (331 aa) initn: 2112 init1: 2112 opt: 2112 Z-score: 2884.4 bits: 542.0 E(85289): 6.4e-154 Smith-Waterman score: 2112; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL 250 260 270 280 290 300 310 320 330 pF1KB5 VVVDENDVVKGIVSLSDILQALVLTGGEKKP ::::::::::::::::::::::::::::::: NP_002 VVVDENDVVKGIVSLSDILQALVLTGGEKKP 310 320 330 >>XP_011536864 (OMIM: 602742) PREDICTED: 5'-AMP-activate (299 aa) initn: 1908 init1: 1908 opt: 1908 Z-score: 2606.5 bits: 490.5 E(85289): 1.9e-138 Smith-Waterman score: 1908; 100.0% identity (100.0% similar) in 299 aa overlap (33-331:1-299) 10 20 30 40 50 60 pF1KB5 TVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFF :::::::::::::::::::::::::::::: XP_011 MKSHRCYDLIPTSSKLVVFDTSLQVKKAFF 10 20 30 70 80 90 100 110 120 pF1KB5 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 QDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 FPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 KFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVV 220 230 240 250 260 270 310 320 330 pF1KB5 VDENDVVKGIVSLSDILQALVLTGGEKKP ::::::::::::::::::::::::::::: XP_011 VDENDVVKGIVSLSDILQALVLTGGEKKP 280 290 >>XP_006719562 (OMIM: 602742) PREDICTED: 5'-AMP-activate (299 aa) initn: 1908 init1: 1908 opt: 1908 Z-score: 2606.5 bits: 490.5 E(85289): 1.9e-138 Smith-Waterman score: 1908; 100.0% identity (100.0% similar) in 299 aa overlap (33-331:1-299) 10 20 30 40 50 60 pF1KB5 TVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFF :::::::::::::::::::::::::::::: XP_006 MKSHRCYDLIPTSSKLVVFDTSLQVKKAFF 10 20 30 70 80 90 100 110 120 pF1KB5 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 QDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 FPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 KFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVV 220 230 240 250 260 270 310 320 330 pF1KB5 VDENDVVKGIVSLSDILQALVLTGGEKKP ::::::::::::::::::::::::::::: XP_006 VDENDVVKGIVSLSDILQALVLTGGEKKP 280 290 >>NP_001193639 (OMIM: 602742) 5'-AMP-activated protein k (299 aa) initn: 1908 init1: 1908 opt: 1908 Z-score: 2606.5 bits: 490.5 E(85289): 1.9e-138 Smith-Waterman score: 1908; 100.0% identity (100.0% similar) in 299 aa overlap (33-331:1-299) 10 20 30 40 50 60 pF1KB5 TVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFF :::::::::::::::::::::::::::::: NP_001 MKSHRCYDLIPTSSKLVVFDTSLQVKKAFF 10 20 30 70 80 90 100 110 120 pF1KB5 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 QDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 FPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 KFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVV 220 230 240 250 260 270 310 320 330 pF1KB5 VDENDVVKGIVSLSDILQALVLTGGEKKP ::::::::::::::::::::::::::::: NP_001 VDENDVVKGIVSLSDILQALVLTGGEKKP 280 290 >>XP_005269076 (OMIM: 602742) PREDICTED: 5'-AMP-activate (368 aa) initn: 1757 init1: 1757 opt: 1769 Z-score: 2415.2 bits: 455.4 E(85289): 8.6e-128 Smith-Waterman score: 1769; 87.2% identity (92.4% similar) in 327 aa overlap (6-331:46-368) 10 20 30 pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKS :. ..: : :::. . .. ... XP_005 GEGGYRGPPPPEGWVPCLPPQSGDCHDVGGSGVAAPDVGRGLPQESFLKRGNQAGRLLQW 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 HRCY-DLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINI .: . .. : :. . :.:::::::::::::::::::::::::::::::::::::: XP_005 RRSFLQIAPQLWKMSI----LKVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINI 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 LHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLP 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 VIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVY 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB5 VALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFE 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB5 GVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 320 330 340 350 360 >>NP_001193638 (OMIM: 602742) 5'-AMP-activated protein k (340 aa) initn: 1576 init1: 1576 opt: 1576 Z-score: 2152.2 bits: 406.6 E(85289): 3.9e-113 Smith-Waterman score: 2084; 97.4% identity (97.4% similar) in 340 aa overlap (1-331:1-340) 10 20 30 40 50 60 pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 FFALVTNGVRAAPLWDSKKQSFV---------GMLTITDFINILHRYYKSALVQIYELEE ::::::::::::::::::::::: :::::::::::::::::::::::::::: NP_001 FFALVTNGVRAAPLWDSKKQSFVVLRALSCPLGMLTITDFINILHRYYKSALVQIYELEE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 HKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 ILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 DEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINR 250 260 270 280 290 300 300 310 320 330 pF1KB5 LVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP :::::::::::::::::::::::::::::::::::::::: NP_001 LVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 310 320 330 340 >>XP_005269077 (OMIM: 602742) PREDICTED: 5'-AMP-activate (247 aa) initn: 1567 init1: 1567 opt: 1567 Z-score: 2142.0 bits: 404.2 E(85289): 1.4e-112 Smith-Waterman score: 1567; 100.0% identity (100.0% similar) in 247 aa overlap (85-331:1-247) 60 70 80 90 100 110 pF1KB5 LQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKI :::::::::::::::::::::::::::::: XP_005 MLTITDFINILHRYYKSALVQIYELEEHKI 10 20 30 120 130 140 150 160 170 pF1KB5 ETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILK 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 FLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEK 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 GRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVE 160 170 180 190 200 210 300 310 320 330 pF1KB5 AEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP ::::::::::::::::::::::::::::::::::::: XP_005 AEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 220 230 240 >>XP_016875112 (OMIM: 602742) PREDICTED: 5'-AMP-activate (247 aa) initn: 1567 init1: 1567 opt: 1567 Z-score: 2142.0 bits: 404.2 E(85289): 1.4e-112 Smith-Waterman score: 1567; 100.0% identity (100.0% similar) in 247 aa overlap (85-331:1-247) 60 70 80 90 100 110 pF1KB5 LQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKI :::::::::::::::::::::::::::::: XP_016 MLTITDFINILHRYYKSALVQIYELEEHKI 10 20 30 120 130 140 150 160 170 pF1KB5 ETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILK 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 FLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEK 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 GRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVE 160 170 180 190 200 210 300 310 320 330 pF1KB5 AEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP ::::::::::::::::::::::::::::::::::::: XP_016 AEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 220 230 240 >>XP_016875111 (OMIM: 602742) PREDICTED: 5'-AMP-activate (247 aa) initn: 1567 init1: 1567 opt: 1567 Z-score: 2142.0 bits: 404.2 E(85289): 1.4e-112 Smith-Waterman score: 1567; 100.0% identity (100.0% similar) in 247 aa overlap (85-331:1-247) 60 70 80 90 100 110 pF1KB5 LQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKI :::::::::::::::::::::::::::::: XP_016 MLTITDFINILHRYYKSALVQIYELEEHKI 10 20 30 120 130 140 150 160 170 pF1KB5 ETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILK 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB5 FLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEK 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB5 GRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVE 160 170 180 190 200 210 300 310 320 330 pF1KB5 AEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP ::::::::::::::::::::::::::::::::::::: XP_016 AEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 220 230 240 >>XP_016867765 (OMIM: 194200,261740,600858,602743) PREDI (327 aa) initn: 1561 init1: 1561 opt: 1564 Z-score: 2136.0 bits: 403.5 E(85289): 3.1e-112 Smith-Waterman score: 1564; 75.0% identity (92.1% similar) in 316 aa overlap (16-330:6-321) 10 20 30 40 50 60 pF1KB5 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKA : .:. .:...:: ::.::.:::..:::::::::::.:::::: XP_016 MLEKLEFEDEVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKA 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 FFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREV :::::.:::::::::.::::::::::::::::::::::::: .::::::::::::::::. XP_016 FFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWREL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 YLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFI :::..::::: :::.::::::: :::.::::::::::: :::.:::::::::::::.::. XP_016 YLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFM 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI ...::: ::...:.:: :::: :::... ::. ::.:::..:.::::::::.:.:::: XP_016 SDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 YSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRL :::::::::::::::::::..::.::::::.:::::.:: : ::::..:.:.:::::: XP_016 YSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRL 240 250 260 270 280 290 310 320 330 pF1KB5 VVVDENDVVKGIVSLSDILQALVLT-GGEKKP :::.: : . ::.:::::::::.:: .: :. XP_016 VVVNEADSIVGIISLSDILQALILTPAGAKQKETETE 300 310 320 331 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:44:06 2016 done: Fri Nov 4 03:44:07 2016 Total Scan time: 6.590 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]