FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5422, 224 aa 1>>>pF1KB5422 224 - 224 aa - 224 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2449+/-0.000593; mu= 11.0408+/- 0.036 mean_var=97.8707+/-19.715, 0's: 0 Z-trim(114.5): 14 B-trim: 0 in 0/53 Lambda= 0.129643 statistics sampled from 15031 (15045) to 15031 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.462), width: 16 Scan time: 2.400 The best scores are: opt bits E(32554) CCDS131.1 FBXO44 gene_id:93611|Hs108|chr1 ( 224) 1583 305.3 2.1e-83 CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 ( 255) 874 172.7 1.9e-43 CCDS81261.1 FBXO44 gene_id:93611|Hs108|chr1 ( 256) 866 171.2 5.5e-43 CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 ( 293) 692 138.7 3.8e-33 CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 ( 296) 367 77.9 7.7e-15 >>CCDS131.1 FBXO44 gene_id:93611|Hs108|chr1 (224 aa) initn: 1583 init1: 1583 opt: 1583 Z-score: 1610.8 bits: 305.3 E(32554): 2.1e-83 Smith-Waterman score: 1583; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL 130 140 150 160 170 180 190 200 210 220 pF1KB5 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP :::::::::::::::::::::::::::::::::::::::::::: CCDS13 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP 190 200 210 220 >>CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 (255 aa) initn: 874 init1: 874 opt: 874 Z-score: 893.3 bits: 172.7 E(32554): 1.9e-43 Smith-Waterman score: 874; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL ::. CCDS13 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 130 140 150 160 170 180 >>CCDS81261.1 FBXO44 gene_id:93611|Hs108|chr1 (256 aa) initn: 1569 init1: 866 opt: 866 Z-score: 885.2 bits: 171.2 E(32554): 5.5e-43 Smith-Waterman score: 1509; 87.5% identity (87.5% similar) in 256 aa overlap (1-224:1-256) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 pF1KB5 Q--------------------------------VRSQARLRVQVPAVRSAPVVRARASGD : ::::::::::::::::::::::::::: CCDS81 QHLPQVPGGGPQGRRVLGGADGYHTAGHRGQGLVRSQARLRVQVPAVRSAPVVRARASGD 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB5 LPARPGDHPAEERCQVEGGLPHILQLPARRPLHLVSARRRGHSLLGRLVRPEGHQQQHHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LPARPGDHPAEERCQVEGGLPHILQLPARRPLHLVSARRRGHSLLGRLVRPEGHQQQHHH 190 200 210 220 230 240 210 220 pF1KB5 RAPAALTPPEPPSAEP :::::::::::::::: CCDS81 RAPAALTPPEPPSAEP 250 >>CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 (293 aa) initn: 686 init1: 686 opt: 692 Z-score: 708.5 bits: 138.7 E(32554): 3.8e-33 Smith-Waterman score: 692; 78.7% identity (91.0% similar) in 122 aa overlap (2-123:9-130) 10 20 30 40 50 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLR :. .::::::::::::::::::::::::::::::::::::::.::::::::: CCDS13 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 EGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQ :::::.:::::::::::::::::::::::.:::::: . :..: ::::.::::.: . CCDS13 EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 RKEFPNDQVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQ .::. .:. CCDS13 GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT 130 140 150 160 170 180 >>CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 (296 aa) initn: 364 init1: 190 opt: 367 Z-score: 379.9 bits: 77.9 E(32554): 7.7e-15 Smith-Waterman score: 367; 40.5% identity (66.2% similar) in 148 aa overlap (2-147:43-188) 10 20 30 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCR :.. ..:::: .::.... .:: .:. :: CCDS13 PEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQACR 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 LVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD-WKIFYFLRSLHRNLLHNPCAEEG ::: :..:.: . :: :: .::.. : . : :. :::: . .::::.:::.:: CCDS13 LVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRRRNLLRNPCGEED 80 90 100 110 120 130 100 110 120 130 140 pF1KB5 FEFWSLDV-NGGDEWKVEDLSRDQRKEFPNDQVRSQARLRVQVPAVRSAPVVRARASGDL .: : :: .::: :.::.: :. :: .:. . . . :.: :. .: : CCDS13 LEGWC-DVEHGGDGWRVEELPGDSGVEFTHDE-SVKKYFASSFEWCRKAQVIDLQAEGYW 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB5 PARPGDHPAEERCQVEGGLPHILQLPARRPLHLVSARRRGHSLLGRLVRPEGHQQQHHHR CCDS13 EELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGGW 200 210 220 230 240 250 224 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:45:27 2016 done: Sat Nov 5 12:45:27 2016 Total Scan time: 2.400 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]