FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5422, 224 aa 1>>>pF1KB5422 224 - 224 aa - 224 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7532+/-0.00026; mu= 13.9687+/- 0.016 mean_var=102.1951+/-21.261, 0's: 0 Z-trim(121.8): 41 B-trim: 1277 in 1/53 Lambda= 0.126870 statistics sampled from 38976 (39026) to 38976 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.458), width: 16 Scan time: 6.900 The best scores are: opt bits E(85289) NP_904319 (OMIM: 609111) F-box only protein 44 iso ( 224) 1583 299.1 4e-81 XP_016858333 (OMIM: 609111) PREDICTED: F-box only ( 224) 1583 299.1 4e-81 NP_001291719 (OMIM: 609111) F-box only protein 44 ( 224) 1583 299.1 4e-81 NP_904320 (OMIM: 609111) F-box only protein 44 iso ( 224) 1583 299.1 4e-81 XP_016858332 (OMIM: 609111) PREDICTED: F-box only ( 255) 874 169.3 5.1e-42 NP_001291720 (OMIM: 609111) F-box only protein 44 ( 255) 874 169.3 5.1e-42 XP_006711108 (OMIM: 609111) PREDICTED: F-box only ( 255) 874 169.3 5.1e-42 NP_149438 (OMIM: 609111) F-box only protein 44 iso ( 255) 874 169.3 5.1e-42 NP_001014765 (OMIM: 609111) F-box only protein 44 ( 255) 874 169.3 5.1e-42 XP_011540737 (OMIM: 609111) PREDICTED: F-box only ( 256) 866 167.9 1.4e-41 XP_016858331 (OMIM: 609111) PREDICTED: F-box only ( 256) 866 167.9 1.4e-41 XP_005263594 (OMIM: 609111) PREDICTED: F-box only ( 256) 866 167.9 1.4e-41 XP_006711106 (OMIM: 609111) PREDICTED: F-box only ( 256) 866 167.9 1.4e-41 XP_005263593 (OMIM: 609111) PREDICTED: F-box only ( 256) 866 167.9 1.4e-41 NP_001317284 (OMIM: 609111) F-box only protein 44 ( 256) 866 167.9 1.4e-41 XP_005263506 (OMIM: 605647) PREDICTED: F-box only ( 293) 692 136.1 6.1e-32 XP_006710634 (OMIM: 605647) PREDICTED: F-box only ( 293) 692 136.1 6.1e-32 XP_011539534 (OMIM: 605647) PREDICTED: F-box only ( 293) 692 136.1 6.1e-32 NP_060908 (OMIM: 605647) F-box only protein 6 [Hom ( 293) 692 136.1 6.1e-32 XP_016856496 (OMIM: 605647) PREDICTED: F-box only ( 293) 692 136.1 6.1e-32 XP_005263505 (OMIM: 605647) PREDICTED: F-box only ( 293) 692 136.1 6.1e-32 XP_005263508 (OMIM: 605647) PREDICTED: F-box only ( 293) 692 136.1 6.1e-32 NP_036300 (OMIM: 607112) F-box only protein 2 [Hom ( 296) 367 76.6 4.9e-14 NP_079183 (OMIM: 609094) F-box only protein 17 iso ( 278) 164 39.4 0.0072 NP_680474 (OMIM: 609094) F-box only protein 17 iso ( 287) 164 39.4 0.0074 >>NP_904319 (OMIM: 609111) F-box only protein 44 isoform (224 aa) initn: 1583 init1: 1583 opt: 1583 Z-score: 1577.4 bits: 299.1 E(85289): 4e-81 Smith-Waterman score: 1583; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL 130 140 150 160 170 180 190 200 210 220 pF1KB5 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP :::::::::::::::::::::::::::::::::::::::::::: NP_904 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP 190 200 210 220 >>XP_016858333 (OMIM: 609111) PREDICTED: F-box only prot (224 aa) initn: 1583 init1: 1583 opt: 1583 Z-score: 1577.4 bits: 299.1 E(85289): 4e-81 Smith-Waterman score: 1583; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL 130 140 150 160 170 180 190 200 210 220 pF1KB5 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP :::::::::::::::::::::::::::::::::::::::::::: XP_016 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP 190 200 210 220 >>NP_001291719 (OMIM: 609111) F-box only protein 44 isof (224 aa) initn: 1583 init1: 1583 opt: 1583 Z-score: 1577.4 bits: 299.1 E(85289): 4e-81 Smith-Waterman score: 1583; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL 130 140 150 160 170 180 190 200 210 220 pF1KB5 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP :::::::::::::::::::::::::::::::::::::::::::: NP_001 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP 190 200 210 220 >>NP_904320 (OMIM: 609111) F-box only protein 44 isoform (224 aa) initn: 1583 init1: 1583 opt: 1583 Z-score: 1577.4 bits: 299.1 E(85289): 4e-81 Smith-Waterman score: 1583; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_904 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL 130 140 150 160 170 180 190 200 210 220 pF1KB5 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP :::::::::::::::::::::::::::::::::::::::::::: NP_904 HLVSARRRGHSLLGRLVRPEGHQQQHHHRAPAALTPPEPPSAEP 190 200 210 220 >>XP_016858332 (OMIM: 609111) PREDICTED: F-box only prot (255 aa) initn: 874 init1: 874 opt: 874 Z-score: 875.3 bits: 169.3 E(85289): 5.1e-42 Smith-Waterman score: 874; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL ::. XP_016 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 130 140 150 160 170 180 >>NP_001291720 (OMIM: 609111) F-box only protein 44 isof (255 aa) initn: 874 init1: 874 opt: 874 Z-score: 875.3 bits: 169.3 E(85289): 5.1e-42 Smith-Waterman score: 874; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL ::. NP_001 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 130 140 150 160 170 180 >>XP_006711108 (OMIM: 609111) PREDICTED: F-box only prot (255 aa) initn: 874 init1: 874 opt: 874 Z-score: 875.3 bits: 169.3 E(85289): 5.1e-42 Smith-Waterman score: 874; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL ::. XP_006 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 130 140 150 160 170 180 >>NP_149438 (OMIM: 609111) F-box only protein 44 isoform (255 aa) initn: 874 init1: 874 opt: 874 Z-score: 875.3 bits: 169.3 E(85289): 5.1e-42 Smith-Waterman score: 874; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_149 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL ::. NP_149 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 130 140 150 160 170 180 >>NP_001014765 (OMIM: 609111) F-box only protein 44 isof (255 aa) initn: 874 init1: 874 opt: 874 Z-score: 875.3 bits: 169.3 E(85289): 5.1e-42 Smith-Waterman score: 874; 99.2% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQLPARRPL ::. NP_001 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 130 140 150 160 170 180 >>XP_011540737 (OMIM: 609111) PREDICTED: F-box only prot (256 aa) initn: 1569 init1: 866 opt: 866 Z-score: 867.4 bits: 167.9 E(85289): 1.4e-41 Smith-Waterman score: 1509; 87.5% identity (87.5% similar) in 256 aa overlap (1-224:1-256) 10 20 30 40 50 60 pF1KB5 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 70 80 90 100 110 120 130 140 pF1KB5 Q--------------------------------VRSQARLRVQVPAVRSAPVVRARASGD : ::::::::::::::::::::::::::: XP_011 QHLPQVPGGGPQGRRVLGGADGYHTAGHRGQGLVRSQARLRVQVPAVRSAPVVRARASGD 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB5 LPARPGDHPAEERCQVEGGLPHILQLPARRPLHLVSARRRGHSLLGRLVRPEGHQQQHHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPARPGDHPAEERCQVEGGLPHILQLPARRPLHLVSARRRGHSLLGRLVRPEGHQQQHHH 190 200 210 220 230 240 210 220 pF1KB5 RAPAALTPPEPPSAEP :::::::::::::::: XP_011 RAPAALTPPEPPSAEP 250 224 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:45:28 2016 done: Sat Nov 5 12:45:29 2016 Total Scan time: 6.900 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]