FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5427, 378 aa 1>>>pF1KB5427 378 - 378 aa - 378 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5116+/-0.000869; mu= 15.0073+/- 0.052 mean_var=60.6802+/-12.071, 0's: 0 Z-trim(105.5): 10 B-trim: 0 in 0/51 Lambda= 0.164646 statistics sampled from 8443 (8449) to 8443 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.26), width: 16 Scan time: 2.640 The best scores are: opt bits E(32554) CCDS5280.1 AGPAT4 gene_id:56895|Hs108|chr6 ( 378) 2591 624.0 6.6e-179 CCDS13703.1 AGPAT3 gene_id:56894|Hs108|chr21 ( 376) 1661 403.1 2.1e-112 CCDS42670.1 LCLAT1 gene_id:253558|Hs108|chr2 ( 376) 387 100.5 2.6e-21 CCDS1772.1 LCLAT1 gene_id:253558|Hs108|chr2 ( 414) 387 100.5 2.8e-21 CCDS34796.1 AGPAT5 gene_id:55326|Hs108|chr8 ( 364) 261 70.6 2.6e-12 >>CCDS5280.1 AGPAT4 gene_id:56895|Hs108|chr6 (378 aa) initn: 2591 init1: 2591 opt: 2591 Z-score: 3325.4 bits: 624.0 E(32554): 6.6e-179 Smith-Waterman score: 2591; 100.0% identity (100.0% similar) in 378 aa overlap (1-378:1-378) 10 20 30 40 50 60 pF1KB5 MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS52 PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE 310 320 330 340 350 360 370 pF1KB5 IDKGSAYGNSDSKQKLND :::::::::::::::::: CCDS52 IDKGSAYGNSDSKQKLND 370 >>CCDS13703.1 AGPAT3 gene_id:56894|Hs108|chr21 (376 aa) initn: 1700 init1: 1651 opt: 1661 Z-score: 2131.6 bits: 403.1 E(32554): 2.1e-112 Smith-Waterman score: 1661; 61.9% identity (84.8% similar) in 375 aa overlap (1-375:1-375) 10 20 30 40 50 60 pF1KB5 MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ : : ..::.::. ::. .::..:::.:: .:: :: :::..:::.:..::::.: . :: CCDS13 MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV ::::::::: ::::.::: . ..:::.:...:::.:::::::::.. ::::.::.::: CCDS13 LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF :::::: :::.::: ::: :.:::.::::.:: ::. .:..: :::: ..::..:::::: CCDS13 LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL :: ::..::.:: ::::: ::.:::::::::. .:. ::..:.:::: :::::.:.::.: CCDS13 TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV ::.: ::::.::. :::.:::::: :. : . :::::::::::.:: : . : :: . CCDS13 LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE : ::::::.:.: ::...: :.:.:..... ::: : . .:. .:: ::: .::::: CCDS13 PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE 310 320 330 340 350 360 370 pF1KB5 IDKGSAYGNSDSKQKLND :.:::.:::.. :.: CCDS13 IEKGSSYGNQEFKKKE 370 >>CCDS42670.1 LCLAT1 gene_id:253558|Hs108|chr2 (376 aa) initn: 279 init1: 250 opt: 387 Z-score: 496.1 bits: 100.5 E(32554): 2.6e-21 Smith-Waterman score: 388; 26.9% identity (56.0% similar) in 323 aa overlap (36-343:29-345) 10 20 30 40 50 60 pF1KB5 LLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLL : : .: . .: :: :: . : :: CCDS42 MVSWKGIYFILTLFWGSFFGSIFMLSPFLPLMFVNPSWYRWINNRLVATWLTLPVALL 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 EWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKVLAKKE : :.. : : :.. : : .....::. ..:.. :. :.. : :. : CCDS42 ETMFGVKVIITGD--AFVP-G-ERSVIIMNHRTRMDWMFLWNCLMRYSYLRLEKICLKAS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRFTEKKH : :: .:: . ..: :::..:.. .... : : .:: ::: .::... CCDS42 LKGVPGFGWAMQAAAYIFIHRKWKDDKSHFEDMIDYFCDIHEPLQLLIFPEGTDLTENSK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 EISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRN--VVSAVYDCTLNFRNNENPTLLGV : :. .:: . .. : ::: ::...: ::. ..::.: :. . .: . . CCDS42 SRSNAFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPHNIPQSEKHL 180 190 200 210 220 230 250 260 270 280 290 pF1KB5 LNGK-KYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYY---RTGTFPETPM :.: . ..:.: :.. .: . .. . : :: ..::. . .: .. : . CCDS42 LQGDFPREIHFHVHRYPIDTLPTSKEDLQLWCHKRWEEKEERLRSFYQGEKNFYFTGQSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 VPPRRPWT------LVNWLFWASLVLYP---FFQFLVSMIRSGSSLTLASFILVFFVASV .:: . :.. :.:. .. : .. .: :... .:.. :.: CCDS42 IPPCKSELRVLVVKLLSILYWT--LFSPAMCLLIYLYSLVKWYFIITIVIFVLQERIFGG 300 310 320 330 340 350 360 370 pF1KB5 GVRWMIGVTEIDKGSAYGNSDSKQKLND CCDS42 LEIIELACYRLLHKQPHLNSKKNE 360 370 >>CCDS1772.1 LCLAT1 gene_id:253558|Hs108|chr2 (414 aa) initn: 279 init1: 250 opt: 387 Z-score: 495.4 bits: 100.5 E(32554): 2.8e-21 Smith-Waterman score: 388; 26.9% identity (56.0% similar) in 323 aa overlap (36-343:67-383) 10 20 30 40 50 60 pF1KB5 LLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLL : : .: . .: :: :: . : :: CCDS17 GIMVSWKGIYFILTLFWGSFFGSIFMLSPFLPLMFVNPSWYRWINNRLVATWLTLPVALL 40 50 60 70 80 90 70 80 90 100 110 120 pF1KB5 EWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKVLAKKE : :.. : : :.. : : .....::. ..:.. :. :.. : :. : CCDS17 ETMFGVKVIITGD--AFVP-G-ERSVIIMNHRTRMDWMFLWNCLMRYSYLRLEKICLKAS 100 110 120 130 140 150 130 140 150 160 170 180 pF1KB5 LAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRFTEKKH : :: .:: . ..: :::..:.. .... : : .:: ::: .::... CCDS17 LKGVPGFGWAMQAAAYIFIHRKWKDDKSHFEDMIDYFCDIHEPLQLLIFPEGTDLTENSK 160 170 180 190 200 210 190 200 210 220 230 240 pF1KB5 EISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRN--VVSAVYDCTLNFRNNENPTLLGV : :. .:: . .. : ::: ::...: ::. ..::.: :. . .: . . CCDS17 SRSNAFAEKNGLQKYEYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPHNIPQSEKHL 220 230 240 250 260 270 250 260 270 280 290 pF1KB5 LNGK-KYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYY---RTGTFPETPM :.: . ..:.: :.. .: . .. . : :: ..::. . .: .. : . CCDS17 LQGDFPREIHFHVHRYPIDTLPTSKEDLQLWCHKRWEEKEERLRSFYQGEKNFYFTGQSV 280 290 300 310 320 330 300 310 320 330 340 350 pF1KB5 VPPRRPWT------LVNWLFWASLVLYP---FFQFLVSMIRSGSSLTLASFILVFFVASV .:: . :.. :.:. .. : .. .: :... .:.. :.: CCDS17 IPPCKSELRVLVVKLLSILYWT--LFSPAMCLLIYLYSLVKWYFIITIVIFVLQERIFGG 340 350 360 370 380 390 360 370 pF1KB5 GVRWMIGVTEIDKGSAYGNSDSKQKLND CCDS17 LEIIELACYRLLHKQPHLNSKKNE 400 410 >>CCDS34796.1 AGPAT5 gene_id:55326|Hs108|chr8 (364 aa) initn: 221 init1: 131 opt: 261 Z-score: 334.6 bits: 70.6 E(32554): 2.6e-12 Smith-Waterman score: 350; 25.0% identity (58.6% similar) in 324 aa overlap (1-310:1-313) 10 20 30 40 50 pF1KB5 MDLAGLLKSQFLCHLVFCYVFIASG-LIINTIQLFTLLLWPINKQLFRKINCRLSYCISS : :. .:.. . .:. :..... . . .. :: . .... .. :: ::. . CCDS34 MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRL-YCVYQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 QLVMLL-EWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGS ..:... : ..:.. .. : : .::: : . ::. .:.. . :. : . :: CCDS34 SMVLFFFENYTGVQILLYGD----LPKNKENIIYLANHQSTVDWIVADILAIRQNALGHV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 KVLAKKELAYVPIIGWMWYFTEM--VFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCE . . :. : ..:. : ::.. .. .:. . ..: . ..:: : ....: : CCDS34 RYVLKEGLKWLPLYG--CYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 GTRFTEKKHEI---SMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFR :::.. .. .. :. : .:: ::: : :: :. .. ..: ..:.:: :. .. CCDS34 GTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYE 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 NN-------ENPTLLGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQE .. :.::. : . . ... :: .:.::.... :::. .. :: . CCDS34 GKDDGGQRRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLI 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 EYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFF :.:.. :. : : : :: CCDS34 EFYES---PD-PERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTW 300 310 320 330 340 378 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:46:51 2016 done: Sat Nov 5 12:46:51 2016 Total Scan time: 2.640 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]