FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5432, 609 aa 1>>>pF1KB5432 609 - 609 aa - 609 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5729+/-0.00091; mu= 18.3277+/- 0.055 mean_var=74.6715+/-15.090, 0's: 0 Z-trim(106.2): 13 B-trim: 85 in 1/50 Lambda= 0.148421 statistics sampled from 8816 (8823) to 8816 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.271), width: 16 Scan time: 3.690 The best scores are: opt bits E(32554) CCDS14021.1 XRCC6 gene_id:2547|Hs108|chr22 ( 609) 3974 860.6 0 CCDS74871.1 XRCC6 gene_id:2547|Hs108|chr22 ( 559) 3551 770.0 0 CCDS74870.1 XRCC6 gene_id:2547|Hs108|chr22 ( 568) 3303 716.9 1.8e-206 >>CCDS14021.1 XRCC6 gene_id:2547|Hs108|chr22 (609 aa) initn: 3974 init1: 3974 opt: 3974 Z-score: 4596.5 bits: 860.6 E(32554): 0 Smith-Waterman score: 3974; 100.0% identity (100.0% similar) in 609 aa overlap (1-609:1-609) 10 20 30 40 50 60 pF1KB5 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL 550 560 570 580 590 600 pF1KB5 EALTKHFQD ::::::::: CCDS14 EALTKHFQD >>CCDS74871.1 XRCC6 gene_id:2547|Hs108|chr22 (559 aa) initn: 3551 init1: 3551 opt: 3551 Z-score: 4107.5 bits: 770.0 E(32554): 0 Smith-Waterman score: 3551; 100.0% identity (100.0% similar) in 544 aa overlap (66-609:16-559) 40 50 60 70 80 90 pF1KB5 DSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKN :::::::::::::::::::::::::::::: CCDS74 MKKQRKNKKRTLKQVCIQSVYISKIISSDRDLLAVVFYGTEKDKN 10 20 30 40 100 110 120 130 140 150 pF1KB5 SVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFS 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB5 DVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISL 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB5 FYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 FYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYN 170 180 190 200 210 220 280 290 300 310 320 330 pF1KB5 LVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETE 230 240 250 260 270 280 340 350 360 370 380 390 pF1KB5 ELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVA 290 300 310 320 330 340 400 410 420 430 440 450 pF1KB5 ALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMAT 350 360 370 380 390 400 460 470 480 490 500 510 pF1KB5 PEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMN 410 420 430 440 450 460 520 530 540 550 560 570 pF1KB5 KRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGK 470 480 490 500 510 520 580 590 600 pF1KB5 FTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD :::::::::::::::::::::::::::::::::: CCDS74 FTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD 530 540 550 >>CCDS74870.1 XRCC6 gene_id:2547|Hs108|chr22 (568 aa) initn: 3303 init1: 3303 opt: 3303 Z-score: 3820.4 bits: 716.9 E(32554): 1.8e-206 Smith-Waterman score: 3625; 93.3% identity (93.3% similar) in 609 aa overlap (1-609:1-568) 10 20 30 40 50 60 pF1KB5 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD ::::: :::::::::::::: CCDS74 DMSIQ-----------------------------------------ELDNPGAKRILELD 70 130 140 150 160 170 180 pF1KB5 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB5 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB5 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB5 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB5 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB5 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB5 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB5 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL 500 510 520 530 540 550 pF1KB5 EALTKHFQD ::::::::: CCDS74 EALTKHFQD 560 609 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:19:28 2016 done: Thu Nov 3 17:19:28 2016 Total Scan time: 3.690 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]