FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5432, 609 aa 1>>>pF1KB5432 609 - 609 aa - 609 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2710+/-0.000376; mu= 20.2095+/- 0.024 mean_var=74.5772+/-14.991, 0's: 0 Z-trim(113.5): 22 B-trim: 642 in 1/51 Lambda= 0.148515 statistics sampled from 22785 (22802) to 22785 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.267), width: 16 Scan time: 9.360 The best scores are: opt bits E(85289) NP_001460 (OMIM: 152690) X-ray repair cross-comple ( 609) 3974 861.1 0 NP_001275905 (OMIM: 152690) X-ray repair cross-com ( 609) 3974 861.1 0 NP_001275907 (OMIM: 152690) X-ray repair cross-com ( 559) 3551 770.5 0 NP_001275906 (OMIM: 152690) X-ray repair cross-com ( 568) 3303 717.4 3.4e-206 >>NP_001460 (OMIM: 152690) X-ray repair cross-complement (609 aa) initn: 3974 init1: 3974 opt: 3974 Z-score: 4599.5 bits: 861.1 E(85289): 0 Smith-Waterman score: 3974; 100.0% identity (100.0% similar) in 609 aa overlap (1-609:1-609) 10 20 30 40 50 60 pF1KB5 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL 550 560 570 580 590 600 pF1KB5 EALTKHFQD ::::::::: NP_001 EALTKHFQD >>NP_001275905 (OMIM: 152690) X-ray repair cross-complem (609 aa) initn: 3974 init1: 3974 opt: 3974 Z-score: 4599.5 bits: 861.1 E(85289): 0 Smith-Waterman score: 3974; 100.0% identity (100.0% similar) in 609 aa overlap (1-609:1-609) 10 20 30 40 50 60 pF1KB5 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL 550 560 570 580 590 600 pF1KB5 EALTKHFQD ::::::::: NP_001 EALTKHFQD >>NP_001275907 (OMIM: 152690) X-ray repair cross-complem (559 aa) initn: 3551 init1: 3551 opt: 3551 Z-score: 4110.2 bits: 770.5 E(85289): 0 Smith-Waterman score: 3551; 100.0% identity (100.0% similar) in 544 aa overlap (66-609:16-559) 40 50 60 70 80 90 pF1KB5 DSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKN :::::::::::::::::::::::::::::: NP_001 MKKQRKNKKRTLKQVCIQSVYISKIISSDRDLLAVVFYGTEKDKN 10 20 30 40 100 110 120 130 140 150 pF1KB5 SVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFS 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB5 DVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISL 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB5 FYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYN 170 180 190 200 210 220 280 290 300 310 320 330 pF1KB5 LVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETE 230 240 250 260 270 280 340 350 360 370 380 390 pF1KB5 ELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVA 290 300 310 320 330 340 400 410 420 430 440 450 pF1KB5 ALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMAT 350 360 370 380 390 400 460 470 480 490 500 510 pF1KB5 PEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMN 410 420 430 440 450 460 520 530 540 550 560 570 pF1KB5 KRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGK 470 480 490 500 510 520 580 590 600 pF1KB5 FTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD :::::::::::::::::::::::::::::::::: NP_001 FTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD 530 540 550 >>NP_001275906 (OMIM: 152690) X-ray repair cross-complem (568 aa) initn: 3303 init1: 3303 opt: 3303 Z-score: 3822.9 bits: 717.4 E(85289): 3.4e-206 Smith-Waterman score: 3625; 93.3% identity (93.3% similar) in 609 aa overlap (1-609:1-568) 10 20 30 40 50 60 pF1KB5 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD ::::: :::::::::::::: NP_001 DMSIQ-----------------------------------------ELDNPGAKRILELD 70 130 140 150 160 170 180 pF1KB5 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB5 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB5 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB5 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB5 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB5 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN 380 390 400 410 420 430 490 500 510 520 530 540 pF1KB5 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB5 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL 500 510 520 530 540 550 pF1KB5 EALTKHFQD ::::::::: NP_001 EALTKHFQD 560 609 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:19:28 2016 done: Thu Nov 3 17:19:30 2016 Total Scan time: 9.360 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]