FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5441, 339 aa 1>>>pF1KB5441 339 - 339 aa - 339 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6158+/-0.000331; mu= 15.1344+/- 0.021 mean_var=87.7036+/-17.239, 0's: 0 Z-trim(117.2): 54 B-trim: 27 in 1/57 Lambda= 0.136951 statistics sampled from 28867 (28921) to 28867 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.339), width: 16 Scan time: 7.770 The best scores are: opt bits E(85289) XP_016868586 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 2474 498.6 8.1e-141 XP_016868589 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 2474 498.6 8.1e-141 NP_680090 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 2474 498.6 8.1e-141 XP_006716307 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 2474 498.6 8.1e-141 NP_680091 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 2474 498.6 8.1e-141 XP_016868587 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 2474 498.6 8.1e-141 NP_680093 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 2474 498.6 8.1e-141 XP_006716308 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 2474 498.6 8.1e-141 XP_011542114 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 2474 498.6 8.1e-141 XP_016868588 (OMIM: 116810) PREDICTED: cathepsin B ( 339) 2474 498.6 8.1e-141 NP_680092 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 2474 498.6 8.1e-141 NP_001899 (OMIM: 116810) cathepsin B isoform 1 pre ( 339) 2474 498.6 8.1e-141 XP_016868590 (OMIM: 116810) PREDICTED: cathepsin B ( 245) 1693 344.1 1.8e-94 NP_001304166 (OMIM: 116810) cathepsin B isoform 2 ( 215) 1404 287.0 2.5e-77 NP_001191344 (OMIM: 616064) tubulointerstitial nep ( 362) 412 91.2 3.7e-18 XP_005271164 (OMIM: 616064) PREDICTED: tubulointer ( 362) 412 91.2 3.7e-18 XP_011540248 (OMIM: 616064) PREDICTED: tubulointer ( 408) 412 91.2 4.1e-18 NP_001191343 (OMIM: 616064) tubulointerstitial nep ( 436) 412 91.2 4.3e-18 NP_071447 (OMIM: 616064) tubulointerstitial nephri ( 467) 412 91.3 4.6e-18 XP_005271163 (OMIM: 616064) PREDICTED: tubulointer ( 440) 355 80.0 1.1e-14 NP_001805 (OMIM: 170650,245000,245010,602365) dipe ( 463) 323 73.7 8.9e-13 NP_001306066 (OMIM: 116820) pro-cathepsin H isofor ( 201) 278 64.5 2.2e-10 XP_016877441 (OMIM: 116820) PREDICTED: pro-catheps ( 297) 277 64.4 3.4e-10 XP_005254238 (OMIM: 116820) PREDICTED: pro-catheps ( 297) 277 64.4 3.4e-10 XP_016877440 (OMIM: 116820) PREDICTED: pro-catheps ( 317) 277 64.5 3.6e-10 NP_004381 (OMIM: 116820) pro-cathepsin H isoform a ( 335) 277 64.5 3.8e-10 NP_001327 (OMIM: 603169) cathepsin Z preproprotein ( 303) 236 56.3 9.6e-08 NP_001324 (OMIM: 603308) cathepsin L2 preproprotei ( 334) 232 55.6 1.8e-07 NP_001188504 (OMIM: 603308) cathepsin L2 prepropro ( 334) 232 55.6 1.8e-07 NP_001186668 (OMIM: 116845) cathepsin S isoform 2 ( 281) 228 54.7 2.7e-07 NP_004070 (OMIM: 116845) cathepsin S isoform 1 pre ( 331) 228 54.8 3.1e-07 NP_001244902 (OMIM: 116880) cathepsin L1 isoform 2 ( 151) 223 53.5 3.3e-07 XP_011543630 (OMIM: 603539,615362) PREDICTED: cath ( 424) 228 54.9 3.7e-07 NP_000387 (OMIM: 265800,601105) cathepsin K prepro ( 329) 226 54.4 4e-07 NP_003784 (OMIM: 603539,615362) cathepsin F precur ( 484) 228 54.9 4.1e-07 NP_001903 (OMIM: 116880) cathepsin L1 isoform 1 pr ( 333) 223 53.8 6.1e-07 NP_001244901 (OMIM: 116880) cathepsin L1 isoform 1 ( 333) 223 53.8 6.1e-07 NP_001244900 (OMIM: 116880) cathepsin L1 isoform 1 ( 333) 223 53.8 6.1e-07 NP_666023 (OMIM: 116880) cathepsin L1 isoform 1 pr ( 333) 223 53.8 6.1e-07 XP_005251773 (OMIM: 116880) PREDICTED: cathepsin L ( 333) 223 53.8 6.1e-07 NP_001325 (OMIM: 600550) cathepsin O preproprotein ( 321) 213 51.8 2.3e-06 XP_011516565 (OMIM: 116880) PREDICTED: cathepsin L ( 272) 210 51.2 3.1e-06 XP_016869782 (OMIM: 116880) PREDICTED: cathepsin L ( 272) 210 51.2 3.1e-06 XP_016866235 (OMIM: 606749) PREDICTED: tubulointer ( 401) 212 51.7 3.2e-06 XP_006715125 (OMIM: 606749) PREDICTED: tubulointer ( 458) 212 51.7 3.5e-06 NP_055279 (OMIM: 606749) tubulointerstitial nephri ( 476) 212 51.7 3.6e-06 XP_016866237 (OMIM: 606749) PREDICTED: tubulointer ( 309) 194 48.0 3.1e-05 XP_016866236 (OMIM: 606749) PREDICTED: tubulointer ( 351) 194 48.1 3.4e-05 XP_011512799 (OMIM: 606749) PREDICTED: tubulointer ( 426) 194 48.2 3.9e-05 XP_016866234 (OMIM: 606749) PREDICTED: tubulointer ( 438) 185 46.4 0.00014 >>XP_016868586 (OMIM: 116810) PREDICTED: cathepsin B iso (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: XP_016 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>XP_016868589 (OMIM: 116810) PREDICTED: cathepsin B iso (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: XP_016 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>NP_680090 (OMIM: 116810) cathepsin B isoform 1 preprop (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: NP_680 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>XP_006716307 (OMIM: 116810) PREDICTED: cathepsin B iso (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: XP_006 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>NP_680091 (OMIM: 116810) cathepsin B isoform 1 preprop (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: NP_680 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>XP_016868587 (OMIM: 116810) PREDICTED: cathepsin B iso (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: XP_016 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>NP_680093 (OMIM: 116810) cathepsin B isoform 1 preprop (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: NP_680 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>XP_006716308 (OMIM: 116810) PREDICTED: cathepsin B iso (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: XP_006 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>XP_011542114 (OMIM: 116810) PREDICTED: cathepsin B iso (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: XP_011 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 >>XP_016868588 (OMIM: 116810) PREDICTED: cathepsin B iso (339 aa) initn: 2474 init1: 2474 opt: 2474 Z-score: 2649.1 bits: 498.6 E(85289): 8.1e-141 Smith-Waterman score: 2474; 100.0% identity (100.0% similar) in 339 aa overlap (1-339:1-339) 10 20 30 40 50 60 pF1KB5 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 250 260 270 280 290 300 310 320 330 pF1KB5 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI ::::::::::::::::::::::::::::::::::::::: XP_016 NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 310 320 330 339 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:23:53 2016 done: Thu Nov 3 17:23:54 2016 Total Scan time: 7.770 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]