FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5443, 193 aa 1>>>pF1KB5443 193 - 193 aa - 193 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2760+/-0.000842; mu= 12.2459+/- 0.050 mean_var=54.7644+/-10.705, 0's: 0 Z-trim(104.7): 42 B-trim: 0 in 0/52 Lambda= 0.173311 statistics sampled from 7985 (8025) to 7985 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.247), width: 16 Scan time: 1.890 The best scores are: opt bits E(32554) CCDS10736.1 CBLN1 gene_id:869|Hs108|chr16 ( 193) 1266 324.6 2.4e-89 CCDS11999.1 CBLN2 gene_id:147381|Hs108|chr18 ( 224) 977 252.3 1.5e-67 CCDS13448.1 CBLN4 gene_id:140689|Hs108|chr20 ( 201) 890 230.6 4.9e-61 CCDS32057.1 CBLN3 gene_id:643866|Hs108|chr14 ( 205) 724 189.1 1.6e-48 CCDS8720.1 CAPRIN2 gene_id:65981|Hs108|chr12 (1077) 341 93.5 4.8e-19 CCDS31793.1 C1QL4 gene_id:338761|Hs108|chr12 ( 238) 296 82.1 2.9e-16 CCDS42737.1 C1QL2 gene_id:165257|Hs108|chr2 ( 287) 277 77.3 9.4e-15 CCDS31156.1 C1QL3 gene_id:389941|Hs108|chr10 ( 255) 271 75.8 2.4e-14 CCDS11492.1 C1QL1 gene_id:10882|Hs108|chr17 ( 258) 269 75.3 3.4e-14 CCDS3904.1 C1QTNF3 gene_id:114899|Hs108|chr5 ( 246) 250 70.6 8.8e-13 CCDS34141.1 C1QTNF3 gene_id:114899|Hs108|chr5 ( 319) 250 70.6 1.1e-12 >>CCDS10736.1 CBLN1 gene_id:869|Hs108|chr16 (193 aa) initn: 1266 init1: 1266 opt: 1266 Z-score: 1717.6 bits: 324.6 E(32554): 2.4e-89 Smith-Waterman score: 1266; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB5 MLGVLELLLLGAAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MLGVLELLLLGAAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 VYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGW 130 140 150 160 170 180 190 pF1KB5 KYSTFSGFLVFPL ::::::::::::: CCDS10 KYSTFSGFLVFPL 190 >>CCDS11999.1 CBLN2 gene_id:147381|Hs108|chr18 (224 aa) initn: 978 init1: 819 opt: 977 Z-score: 1326.0 bits: 252.3 E(32554): 1.5e-67 Smith-Waterman score: 977; 79.8% identity (88.6% similar) in 193 aa overlap (2-193:32-224) 10 20 30 pF1KB5 MLGVLELLLLGAAWLAGPARGQNETEPIVLE ::: ::: :.:.::.::::::: CCDS11 QAPGRGPLGLRLMMPGRRGALREPGGCGSCLGVALALLLLLLPACCPVRAQNDTEPIVLE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 GKCLVVCDSNPTSDPTGTA-LGISVRSGSAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVL :::::::::.:..: . :. :::::::::::::::: ::::::::::::::: ::::::: CCDS11 GKCLVVCDSSPSADGAVTSSLGISVRSGSAKVAFSATRSTNHEPSEMSNRTMTIYFDQVL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 VNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTR :::::.:: : :.:::::::::.::::::::::::::::: ::.:::::::::::::: CCDS11 VNIGNHFDLASSIFVAPRKGIYSFSFHVVKVYNRQTIQVSLMQNGYPVISAFAGDQDVTR 130 140 150 160 170 180 160 170 180 190 pF1KB5 EAASNGVLIQMEKGDRAYLKLERGNLMGGWKYSTFSGFLVFPL ::::::::. ::. :...::::::::::::::::::::::::: CCDS11 EAASNGVLLLMEREDKVHLKLERGNLMGGWKYSTFSGFLVFPL 190 200 210 220 >>CCDS13448.1 CBLN4 gene_id:140689|Hs108|chr20 (201 aa) initn: 664 init1: 509 opt: 890 Z-score: 1209.2 bits: 230.6 E(32554): 4.9e-61 Smith-Waterman score: 890; 74.3% identity (91.6% similar) in 179 aa overlap (18-193:24-201) 10 20 30 40 50 pF1KB5 MLGVLELLLLGAAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTA---L :. .::.::::::::::::::::::..: :.. : CCDS13 MGSGRRALSAVPAVLLVLTLPGLPVWAQNDTEPIVLEGKCLVVCDSNPATDSKGSSSSPL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 GISVRSGSAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGI :::::....::::::.::::::::::::.: ::::::.:::.:: : : :.:.:::::: CCDS13 GISVRAANSKVAFSAVRSTNHEPSEMSNKTRIIYFDQILVNVGNFFTLE-SVFVAPRKGI 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 YSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKL :::.:::.:::. :::::.::::: :::::::::.:::::::.::::. ..: :..:::: CCDS13 YSFSFHVIKVYQSQTIQVNLMLNGKPVISAFAGDKDVTREAATNGVLLYLDKEDKVYLKL 120 130 140 150 160 170 180 190 pF1KB5 ERGNLMGGWKYSTFSGFLVFPL :.:::.:::.:::::::::::: CCDS13 EKGNLVGGWQYSTFSGFLVFPL 180 190 200 >>CCDS32057.1 CBLN3 gene_id:643866|Hs108|chr14 (205 aa) initn: 709 init1: 553 opt: 724 Z-score: 984.8 bits: 189.1 E(32554): 1.6e-48 Smith-Waterman score: 724; 58.8% identity (80.4% similar) in 194 aa overlap (4-193:21-205) 10 20 30 40 pF1KB5 MLGVLELLLLGAAWLAGPARGQNETEPIVLEGKCLVVCDSN-- :: :: :::.: .:. .::..:::.:::::. . CCDS32 MLGAKPHWLPGPLHSPGLPLVLVLLALGAGW------AQEGSEPVLLEGECLVVCEPGRA 10 20 30 40 50 50 60 70 80 90 pF1KB5 PTSDPTGTALGISVRSGSAKVAFSAIRSTNHEPS-EMSNRTM-IIYFDQVLVNIGNNFDS .. : :.::: .. ..:::.:.:: .:::. : .: : ::::::::: :..:: CCDS32 AAGGPGGAALG---EAPPGRVAFAAVRSHHHEPAGETGNGTSGAIYFDQVLVNEGGGFDR 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB5 ERSTFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLI ..:.:: .:.::: :::::::::::.::::::: ::::::::.: :::::::...::. CCDS32 ASGSFVAPVRGVYSFRFHVVKVYNRQTVQVSLMLNTWPVISAFANDPDVTREAATSSVLL 120 130 140 150 160 170 160 170 180 190 pF1KB5 QMEKGDRAYLKLERGNLMGGWKYSTFSGFLVFPL .. :::. :.:.::::.::::::.:::::.::: CCDS32 PLDPGDRVSLRLRRGNLLGGWKYSSFSGFLIFPL 180 190 200 >>CCDS8720.1 CAPRIN2 gene_id:65981|Hs108|chr12 (1077 aa) initn: 317 init1: 218 opt: 341 Z-score: 455.4 bits: 93.5 E(32554): 4.8e-19 Smith-Waterman score: 341; 37.9% identity (68.6% similar) in 153 aa overlap (42-191:926-1075) 20 30 40 50 60 pF1KB5 AAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRS--GSAKVAFSAIRS :...:..: : . : . .::::: :. CCDS87 QVSSPERDNETFNSGDSGQGDSRSMTPVDVPVTNPAATILPVHVYPLPQQMRVAFSAART 900 910 920 930 940 950 70 80 90 100 110 120 pF1KB5 TNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYNRQTIQV .: :. ... : :: .: :.:..:: . . : : .: : : ::..:. . : CCDS87 SNLAPGTLDQ---PIVFDLLLNNLGETFDLQLGRFNCPVNGTYVFIFHMLKLAVNVPLYV 960 970 980 990 1000 1010 130 140 150 160 170 180 pF1KB5 SLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGG-WKYSTFSGF .:: : ..::.:.: .:.::: ...:. .::. .:.:.:: ..:. ::::::::. CCDS87 NLMKNEEVLVSAYANDGAPDHETASNHAILQLFQGDQIWLRLHRGAIYGSSWKYSTFSGY 1020 1030 1040 1050 1060 1070 190 pF1KB5 LVFPL :.. CCDS87 LLYQD >>CCDS31793.1 C1QL4 gene_id:338761|Hs108|chr12 (238 aa) initn: 338 init1: 128 opt: 296 Z-score: 405.3 bits: 82.1 E(32554): 2.9e-16 Smith-Waterman score: 301; 31.7% identity (57.5% similar) in 186 aa overlap (11-192:64-237) 10 20 30 40 pF1KB5 MLGVLELLLLGAAWLAGPARGQNETEPIVLEGKCLVVCDS : : : :: . : :. CCDS31 PHGPRGPGPDGAPASVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGR------P 40 50 60 70 80 50 60 70 80 90 pF1KB5 NPTSDPTGTALGISVRSGSA-KVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDS .: . : :.. .: . ..:: : :: : .. ::.:..:.:: ... CCDS31 GPPGPPGPGPGGVAPAAGYVPRIAFYAGLRRPHEGYE------VLRFDDVVTNVGNAYEA 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB5 ERSTFIAPRKGIYSFNFHVV-KVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVL . : : :.: : .::. . . .. ..:: :: ::.: : : . . :::.:. CCDS31 ASGKFTCPMPGVYFFAYHVLMRGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVI 150 160 170 180 190 200 160 170 180 190 pF1KB5 IQMEKGDRAYLKLERGNLMGGW--KYSTFSGFLVFPL .... ::....::. :.. :: ::::::::...: CCDS31 LHLDVGDEVFIKLDGGKVHGGNTNKYSTFSGFIIYPD 210 220 230 >>CCDS42737.1 C1QL2 gene_id:165257|Hs108|chr2 (287 aa) initn: 266 init1: 118 opt: 277 Z-score: 378.3 bits: 77.3 E(32554): 9.4e-15 Smith-Waterman score: 277; 35.0% identity (66.4% similar) in 143 aa overlap (53-192:150-286) 30 40 50 60 70 80 pF1KB5 NETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSAKVAFSAIRSTNHEPSEMSNRTM .:. .. :.:: . .. :: : CCDS42 QLTAGTASGVGVVGGGAGVGGDSEGEVTSALSATFSGPKIAFYVGLKSPHEGYE------ 120 130 140 150 160 170 90 100 110 120 130 140 pF1KB5 IIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVV-KVYNRQTIQVSLMLNGWPVISA .. ::.:..:.::..: . : .::: :..:.. . . .. ..: :: :: CCDS42 VLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASA 180 190 200 210 220 230 150 160 170 180 190 pF1KB5 FAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGW--KYSTFSGFLVFPL .: : : . . :::.:......::..:.::. :. :: :::::::::..: CCDS42 IAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD 240 250 260 270 280 >>CCDS31156.1 C1QL3 gene_id:389941|Hs108|chr10 (255 aa) initn: 283 init1: 115 opt: 271 Z-score: 371.1 bits: 75.8 E(32554): 2.4e-14 Smith-Waterman score: 271; 34.6% identity (63.4% similar) in 153 aa overlap (42-191:108-253) 20 30 40 50 60 70 pF1KB5 AAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSAKVAFSAIRSTN : . .: :.. .. : :.:: : . . CCDS31 PGEPGPPGPMGPPGEKGEPGRQGLPGPPGAPGLNAAG-AISAATYSTVPKIAFYAGLKRQ 80 90 100 110 120 130 80 90 100 110 120 130 pF1KB5 HEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVV-KVYNRQTIQVS :: : .. ::.:..:.::..: . : ::: :..::. . . .. .. CCDS31 HEGYE------VLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWAD 140 150 160 170 180 190 140 150 160 170 180 pF1KB5 LMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGW--KYSTFSGF : :. ::.: : : . . :::.:....: ::..:.::. :. :: :::::::: CCDS31 LCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGF 200 210 220 230 240 250 190 pF1KB5 LVFPL ... CCDS31 IIYAD >>CCDS11492.1 C1QL1 gene_id:10882|Hs108|chr17 (258 aa) initn: 313 init1: 115 opt: 269 Z-score: 368.3 bits: 75.3 E(32554): 3.4e-14 Smith-Waterman score: 269; 33.3% identity (63.4% similar) in 153 aa overlap (42-191:111-256) 20 30 40 50 60 70 pF1KB5 AAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSAKVAFSAIRSTN : . .: :.. .. . .::: : .. CCDS11 PGPPGDPGPPGPVGPPGEKGEPGKPGPPGLPGAGGSG-AISTATYTTVPRVAFYAGLKNP 90 100 110 120 130 80 90 100 110 120 130 pF1KB5 HEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVV-KVYNRQTIQVS :: : .. ::.:..:.:::.:. . : : : :..::. . . .. .. CCDS11 HEGYE------VLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWAD 140 150 160 170 180 190 140 150 160 170 180 pF1KB5 LMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGW--KYSTFSGF : :: ::.: : : . . :::.:..... ::....::. :. :: :::::::: CCDS11 LCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGF 200 210 220 230 240 250 190 pF1KB5 LVFPL ... CCDS11 IIYSD >>CCDS3904.1 C1QTNF3 gene_id:114899|Hs108|chr5 (246 aa) initn: 259 init1: 205 opt: 250 Z-score: 342.9 bits: 70.6 E(32554): 8.8e-13 Smith-Waterman score: 250; 34.8% identity (65.9% similar) in 132 aa overlap (61-191:117-243) 40 50 60 70 80 90 pF1KB5 EGKCLVVCDSNPTSDPTGTALGISVRSGSAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVL ..:: : .:. .::.. : :..: CCDS39 GDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATH-----FSNQNSGIIFSSVE 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB5 VNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTR .:::: :: . : :: .:.: :.: ..: . . . : :: :: :.: .. .. CCDS39 TNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKS 150 160 170 180 190 200 160 170 180 190 pF1KB5 EAASNGVLIQMEKGDRAYLKLERGNLMGG-WKYSTFSGFLVFPL ...:: ..... :::...:.. : : : ..:::.:::.: CCDS39 DTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK 210 220 230 240 193 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:48:39 2016 done: Sat Nov 5 12:48:39 2016 Total Scan time: 1.890 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]