FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5446, 655 aa 1>>>pF1KB5446 655 - 655 aa - 655 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8313+/-0.000938; mu= 16.9159+/- 0.056 mean_var=72.8629+/-14.734, 0's: 0 Z-trim(105.3): 30 B-trim: 8 in 1/48 Lambda= 0.150252 statistics sampled from 8304 (8328) to 8304 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.256), width: 16 Scan time: 3.690 The best scores are: opt bits E(32554) CCDS11090.1 ACADVL gene_id:37|Hs108|chr17 ( 655) 4259 932.9 0 CCDS58509.1 ACADVL gene_id:37|Hs108|chr17 ( 678) 4133 905.6 0 CCDS42249.1 ACADVL gene_id:37|Hs108|chr17 ( 633) 3829 839.6 0 CCDS3053.1 ACAD9 gene_id:28976|Hs108|chr3 ( 621) 1697 377.5 3.1e-104 CCDS10057.2 IVD gene_id:3712|Hs108|chr15 ( 426) 717 165.0 2e-40 CCDS9207.1 ACADS gene_id:35|Hs108|chr12 ( 412) 714 164.3 3e-40 CCDS53930.1 IVD gene_id:3712|Hs108|chr15 ( 396) 712 163.9 3.9e-40 CCDS7634.1 ACADSB gene_id:36|Hs108|chr10 ( 432) 710 163.5 5.7e-40 CCDS81518.1 ACADSB gene_id:36|Hs108|chr10 ( 330) 674 155.6 1e-37 CCDS65562.1 ACADM gene_id:34|Hs108|chr1 ( 385) 633 146.8 5.4e-35 CCDS668.1 ACADM gene_id:34|Hs108|chr1 ( 421) 633 146.8 5.9e-35 CCDS44165.1 ACADM gene_id:34|Hs108|chr1 ( 425) 633 146.8 5.9e-35 CCDS72807.1 ACADM gene_id:34|Hs108|chr1 ( 454) 611 142.0 1.7e-33 CCDS8498.1 ACAD8 gene_id:27034|Hs108|chr11 ( 415) 576 134.4 3e-31 CCDS2389.1 ACADL gene_id:33|Hs108|chr2 ( 430) 565 132.0 1.6e-30 CCDS76610.1 ACADS gene_id:35|Hs108|chr12 ( 408) 481 113.8 4.7e-25 CCDS3074.1 ACAD11 gene_id:84129|Hs108|chr3 ( 780) 339 83.2 1.5e-15 CCDS31903.1 ACAD10 gene_id:80724|Hs108|chr12 (1059) 339 83.2 2e-15 CCDS44973.1 ACAD10 gene_id:80724|Hs108|chr12 (1090) 339 83.2 2.1e-15 CCDS12286.1 GCDH gene_id:2639|Hs108|chr19 ( 438) 297 74.0 5.1e-13 >>CCDS11090.1 ACADVL gene_id:37|Hs108|chr17 (655 aa) initn: 4259 init1: 4259 opt: 4259 Z-score: 4986.0 bits: 932.9 E(32554): 0 Smith-Waterman score: 4259; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655) 10 20 30 40 50 60 pF1KB5 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF 610 620 630 640 650 >>CCDS58509.1 ACADVL gene_id:37|Hs108|chr17 (678 aa) initn: 4133 init1: 4133 opt: 4133 Z-score: 4838.1 bits: 905.6 E(32554): 0 Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 635 aa overlap (21-655:44-678) 10 20 30 40 50 pF1KB5 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALD :::::::::::::::::::::::::::::: CCDS58 MGKEIEAEAQRPLRQTWRPGQPPAMTAKTMSSRLTALLGQPRPGPARRPYAGGAAQLALD 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB5 KSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVS 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB5 RFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMH 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB5 DLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRT 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB5 SAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGG 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB5 ITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAG 320 330 340 350 360 370 360 370 380 390 400 410 pF1KB5 TMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATD 380 390 400 410 420 430 420 430 440 450 460 470 pF1KB5 FQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRL 440 450 460 470 480 490 480 490 500 510 520 530 pF1KB5 FVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELS 500 510 520 530 540 550 540 550 560 570 580 590 pF1KB5 RSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLS 560 570 580 590 600 610 600 610 620 630 640 650 pF1KB5 EGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTS 620 630 640 650 660 670 pF1KB5 NPLGF ::::: CCDS58 NPLGF >>CCDS42249.1 ACADVL gene_id:37|Hs108|chr17 (633 aa) initn: 3819 init1: 3819 opt: 3829 Z-score: 4482.5 bits: 839.6 E(32554): 0 Smith-Waterman score: 4065; 96.6% identity (96.6% similar) in 655 aa overlap (1-655:1-633) 10 20 30 40 50 60 pF1KB5 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL :::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQ-------------- 10 20 30 40 70 80 90 100 110 120 pF1KB5 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 --------ESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB5 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB5 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK 520 530 540 550 560 570 610 620 630 640 650 pF1KB5 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF 580 590 600 610 620 630 >>CCDS3053.1 ACAD9 gene_id:28976|Hs108|chr3 (621 aa) initn: 948 init1: 566 opt: 1697 Z-score: 1984.9 bits: 377.5 E(32554): 3.1e-104 Smith-Waterman score: 1697; 46.6% identity (75.0% similar) in 599 aa overlap (60-653:29-617) 30 40 50 60 70 80 pF1KB5 QPRPGPARRPYAGGAAQLALDKSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFP : : .: ..:: .: :.. .::: CCDS30 MSGCGLFLRTTAAARACRGLVVSTANRRLLRTSP---PVRAFAKELFLGKIKKKEVFP 10 20 30 40 50 90 100 110 120 130 140 pF1KB5 YPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSE .: : ..: .. ..... :: .:: : : : : . . : . :: :: :::::: : CCDS30 FPEVSQDELNE-INQFLGPVEKFFTEEVDSRKIDQEGKIPDETLEKLKSLGLFGLQVPEE 60 70 80 90 100 110 150 160 170 180 190 200 pF1KB5 LGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGE ::.:. ::.:.:: ::..: : .. .::.:::.::.:::.: ::. :: :::::::::: CCDS30 YGGLGFSNTMYSRLGEIISM-DGSITVTLAAHQAIGLKGIILAGTEEQKAKYLPKLASGE 120 130 140 150 160 170 210 220 230 240 250 260 pF1KB5 TVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD .::::::::.:::::::::. :. : :.: :::::.::.:::::.:::::::: :.: CCDS30 HIAAFCLTEPASGSDAASIRSRATLSEDKKHYILNGSKVWITNGGLANIFTVFAKTEVVD 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB5 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSG . :.::.:::::.::: :::.:.: :: :.::..::: :: :.....: ::.:::::.: CCDS30 -SDGSVKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVHFENTKIPVENILGEVGDG 240 250 260 270 280 290 330 340 350 360 370 380 pF1KB5 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVML :::::.:::.:::.:....:: .. .: ....: .: ::.... .:::::::.: :.. CCDS30 FKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQFNKRLSEFGLIQEKFALMAQK 300 310 320 330 340 350 390 400 410 420 430 440 pF1KB5 QYVTESMAYMVSANMDQ-GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGV :: :::.:.... .:: : : .::::. :.:.:::::. ..: .::.::.:. .. CCDS30 AYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGLGYTRDYPY 360 370 380 390 400 410 450 460 470 480 490 500 pF1KB5 ERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQ ::.::: ::. ::::::.:::...:: : . :. :. ::. .... .. .:.. CCDS30 ERILRDTRILLIFEGTNEILRMYIALTGLQHAGRILTTRIHELKQ--AKVSTVMDTVGRR 420 430 440 450 460 470 510 520 530 540 550 560 pF1KB5 LRRRAGLGSGLSLSG---LVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLL :: : :.:.: .::: :. :.. . :. .::. :.. : :..::..: CCDS30 LRDSLGRTVDLGLTGNHGVVHPSLADSANKFEENTYCFGRTVETLLLRFGKTIMEEQLVL 480 490 500 510 520 530 570 580 590 600 610 620 pF1KB5 QRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDP .:.:. :.::.:..::::::::. : . .:: .: .:.:.:: ... .. : : CCDS30 KRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANTFCVEA--YLQNLFSLSQLDK 540 550 560 570 580 630 640 650 pF1KB5 WQQE-LYRNFKSISKALVERGGVVTSNPLGF . : : ...:..:. ..:. . . ..:: CCDS30 YAPENLDEQIKKVSQQILEKRAYICAHPLDRTC 590 600 610 620 >>CCDS10057.2 IVD gene_id:3712|Hs108|chr15 (426 aa) initn: 708 init1: 261 opt: 717 Z-score: 839.4 bits: 165.0 E(32554): 2e-40 Smith-Waterman score: 717; 32.8% identity (68.0% similar) in 384 aa overlap (94-472:45-417) 70 80 90 100 110 120 pF1KB5 KPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA--- :.::: : : . ...:..: : CCDS10 VASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQ----LRQTMAKFLQEHLAPKAQE 20 30 40 50 60 70 130 140 150 160 170 pF1KB5 --KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITL ... .. ..: :. : .::..:. .: . :: :: ... ..: .. . .::.. CCDS10 IDRSNEFKNLREF-WKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSY 80 90 100 110 120 180 190 200 210 220 230 pF1KB5 GAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCG :::... .. .. :..:::::::::: ::: ..:. ..::..:::..:.. .: . : CCDS10 GAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKK--G 130 140 150 160 170 180 240 250 260 270 280 290 pF1KB5 KYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEK ..: :::.:.::.:: ::.. :.:: :: :. ... ::::.::.:. :.. . CCDS10 NHYILNGNKFWITNGPDADVLIVYAK---TDLAAVPASRGITAFIVEKGMPGFSTSKKLD 190 200 210 220 230 240 300 310 320 330 340 350 pF1KB5 KMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAK :.:...::: :..:. ..:. :.::. ..: : : :. :. .:.. : :.... . CCDS10 KLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDH 250 260 270 280 290 300 360 370 380 390 400 410 pF1KB5 AVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAIS .. . : ::.:: .: :.: :.: : .. ....: :. :.: . :.. CCDS10 TIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVI 310 320 330 340 350 360 420 430 440 450 460 470 pF1KB5 KIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCM ....: : .:. . :: .:: :.... . : ::: ....: ::... :: . CCDS10 -LYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNA 370 380 390 400 410 420 480 490 500 510 520 530 pF1KB5 DKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVR CCDS10 DFH >>CCDS9207.1 ACADS gene_id:35|Hs108|chr12 (412 aa) initn: 711 init1: 280 opt: 714 Z-score: 836.1 bits: 164.3 E(32554): 3e-40 Smith-Waterman score: 714; 35.5% identity (62.7% similar) in 386 aa overlap (90-473:29-403) 60 70 80 90 100 110 pF1KB5 LTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDP : :: : :. :.. : :. : CCDS92 MAAALLARASGPARRALCPRAWRQLHTIYQSVELPETHQM---LLQTCRDFAEKELFP 10 20 30 40 50 120 130 140 150 160 170 pF1KB5 --AKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGIT :. : .. . . . :: ....:: ::::.:: :: .: .. ..:. CCDS92 IAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVI 60 70 80 90 100 110 180 190 200 210 220 230 pF1KB5 LGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPC .....:. . :: ::.: ::. .. ..::. .. : :.::..::::.. :.: CCDS92 MSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAE-- 120 130 140 150 160 170 240 250 260 270 280 290 pF1KB5 GKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPE : ..:::.: ::.:. :. .:::.: . : :.::.: :.: : : CCDS92 GDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKG-----ISAFLVPMPTPGLTLGKKE 180 190 200 210 220 300 310 320 330 340 350 pF1KB5 KKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIA :.::..:.::...:. :.:....::: : :::.::. :. ::.:.:. : . . CCDS92 DKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALD 230 240 250 260 270 280 360 370 380 390 400 410 pF1KB5 KAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAI ::..: :: :: . .. .:: ::: :. : . . .: . .. : :::. CCDS92 CAVNYAENRMAFGAPLTKLQVIQFKLADMA-LALESARLLTWRAAMLKDNKKPFIKEAAM 290 300 310 320 330 340 420 430 440 450 460 470 pF1KB5 SKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGC .:. .:::: .. . :::.::::.. : .:: :: :: .:.:::..: :: .: CCDS92 AKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLL 350 360 370 380 390 400 480 490 500 510 520 530 pF1KB5 MDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAV CCDS92 RSYRS 410 >>CCDS53930.1 IVD gene_id:3712|Hs108|chr15 (396 aa) initn: 708 init1: 261 opt: 712 Z-score: 834.1 bits: 163.9 E(32554): 3.9e-40 Smith-Waterman score: 712; 33.8% identity (68.5% similar) in 355 aa overlap (118-472:39-387) 90 100 110 120 130 140 pF1KB5 FPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVP : : : : .. :. : .::..:. .: CCDS53 RLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQEFWKQLGNLGVLGITAP 10 20 30 40 50 60 150 160 170 180 190 200 pF1KB5 SELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLAS . :: :: ... ..: .. . .::.. :::... .. .. :..:::::::::: : CCDS53 VQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLIS 70 80 90 100 110 120 210 220 230 240 250 260 pF1KB5 GETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPV :: ..:. ..::..:::..:.. .: . :..: :::.:.::.:: ::.. :.::: CCDS53 GEYIGALAMSEPNAGSDVVSMKLKAEKK--GNHYILNGNKFWITNGPDADVLIVYAKT-- 130 140 150 160 170 180 270 280 290 300 310 320 pF1KB5 TDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVG : :. ... ::::.::.:. :.. . :.:...::: :..:. ..:. :.::. . CCDS53 -DLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHEN 190 200 210 220 230 240 330 340 350 360 370 380 pF1KB5 SGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMV .: : : :. :. .:.. : :.... ... . : ::.:: .: :.: :.: : CCDS53 KGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMY 250 260 270 280 290 300 390 400 410 420 430 440 pF1KB5 MLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPG .. ....: :. :.: . :.. ....: : .:. . :: .:: :.... CCDS53 TRLMACRQYVYNVAKACDEGHCTAKDCAGVI-LYSAECATQVALDGIQCFGGNGYINDFP 310 320 330 340 350 360 450 460 470 480 490 500 pF1KB5 VERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGK . : ::: ....: ::... :: . CCDS53 MGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH 370 380 390 >>CCDS7634.1 ACADSB gene_id:36|Hs108|chr10 (432 aa) initn: 644 init1: 281 opt: 710 Z-score: 831.1 bits: 163.5 E(32554): 5.7e-40 Smith-Waterman score: 710; 34.3% identity (67.0% similar) in 361 aa overlap (109-467:68-419) 80 90 100 110 120 130 pF1KB5 KGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGL :..: .: : . : .:... ::: CCDS76 SEALLNITNNGIHFAPLQTFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB5 KELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKA . : .:..: : ::.: . . ..: .. : .:.. .... : ::. CCDS76 FQQGLMGIEVDPEYGGTGASFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEE 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB5 QKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLA :: :::.:.. : :..:::.: ..:::. ...: : . : ::.:::::.:::.. : CCDS76 QKATYLPQLTT-EKVGSFCLSEAGAGSDSFALKTRA--DKEGDYYVLNGSKMWISSAEHA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB5 DIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVR .: :.:.. ::. : . ::.:.:.: :. : ::.:.:..::.: . :..:. CCDS76 GLFLVMANV---DPTIG--YKGITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVK 220 230 240 250 260 320 330 340 350 360 370 pF1KB5 VPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNF :: :.::..: :.: :. ::.::.:.:: . : .: . .. . .: :::... .: CCDS76 VPEANILGQIGHGYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDF 270 280 290 300 310 320 380 390 400 410 420 430 pF1KB5 GLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQI .:...:... ... ..: .. .. : : ::...: ..:: : ..:..::. CCDS76 QGLQHQVAHVATQLEAARLLTYNAARLLEAGKP-FIKEASMAKYYASEIAGQTTSKCIEW 330 340 350 360 370 380 440 450 460 470 480 490 pF1KB5 MGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFG :::.:. :. ::. .:: .: :.::...: CCDS76 MGGVGYTKDYPVEKYFRDAKIGTIYEGASNIQLNTIAKHIDAEY 390 400 410 420 430 500 510 520 530 540 550 pF1KB5 NAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKK >>CCDS81518.1 ACADSB gene_id:36|Hs108|chr10 (330 aa) initn: 585 init1: 281 opt: 674 Z-score: 790.8 bits: 155.6 E(32554): 1e-37 Smith-Waterman score: 674; 35.1% identity (68.3% similar) in 325 aa overlap (143-467:2-317) 120 130 140 150 160 170 pF1KB5 FEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDL :..: : ::.: . . ..: .. : CCDS81 MGIEVDPEYGGTGASFLSTVLVIEELAKVDA 10 20 30 180 190 200 210 220 230 pF1KB5 GVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSA .:.. .... : ::. :: :::.:.. : :..:::.: ..:::. ...: : CCDS81 SVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGSFCLSEAGAGSDSFALKTRA 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB5 VPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGIT . : ::.:::::.:::.. : .: :.:.. ::. : . ::.:.:.: :. CCDS81 --DKEGDYYVLNGSKMWISSAEHAGLFLVMANV---DPTIG--YKGITSFLVDRDTPGLH 100 110 120 130 140 300 310 320 330 340 350 pF1KB5 HGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTM : ::.:.:..::.: . :..:.:: :.::..: :.: :. ::.::.:.:: . : CCDS81 IGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSLNEGRIGIAAQMLGLA 150 160 170 180 190 200 360 370 380 390 400 410 pF1KB5 RGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQ .: . .. . .: :::... .: .:...:... ... ..: .. .. : : CCDS81 QGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTYNAARLLEAGKP-FI 210 220 230 240 250 260 420 430 440 450 460 470 pF1KB5 IEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV ::...: ..:: : ..:..::. :::.:. :. ::. .:: .: :.::...: CCDS81 KEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIGTIYEGASNIQLNTI 270 280 290 300 310 320 480 490 500 510 520 530 pF1KB5 ALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRS CCDS81 AKHIDAEY 330 >>CCDS65562.1 ACADM gene_id:34|Hs108|chr1 (385 aa) initn: 445 init1: 213 opt: 633 Z-score: 741.7 bits: 146.8 E(32554): 5.4e-35 Smith-Waterman score: 637; 33.3% identity (64.8% similar) in 384 aa overlap (100-482:18-384) 70 80 90 100 110 120 pF1KB5 SKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVE .: .: . ::. ...... . ... CCDS65 MLQEFTEQQKEFQATARKFAREEIIPVAAEYDKTGE----YPVPLIR 10 20 30 40 130 140 150 160 170 180 pF1KB5 ETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGI .. : ::: .. ..: . ::.:: . . . : ... :: .. .. :.: : CCDS65 RA-W----ELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPI 50 60 70 80 90 190 200 210 220 230 240 pF1KB5 LLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLW .. :. ::.::: ... . :.:.:::..:::.:.:.:.: . : : .::.:.: CCDS65 IIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK--GDEYIINGQKMW 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB5 ISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAE :.::: :. . ..:.. :: . : : .:.:.:: :: : : .:: . :.: CCDS65 ITNGGKANWYFLLARSD-PDPKAPANKA-FTGFIVEADTPGIQIGRKELNMGQRCSDTRG 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB5 VFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQF . :. :.::.:::: :.:::::: ... : .::. .: . . .:. .: .: : CCDS65 IVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTF 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB5 GEKIHNFGLIQEKLARMVMLQYVTESMAYMVSA-NMDQGATDFQIEAAISKIFGSEAAWK :. . . :. ::.:.: . :.:. .: ..:.: . :.:.: :... : . CCDS65 GKLLVEHQAISFMLAEMAM-KVELARMSYQRAAWEVDSGRRNTYY-ASIAKAFAGDIANQ 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB5 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG .. . .::.:: :: : ::...:: .:..:.:::..: ::.:: . .:: : CCDS65 LATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREH-IDKYKN 340 350 360 370 380 490 500 510 520 530 540 pF1KB5 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE 655 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:16:20 2016 done: Sat Nov 5 07:16:21 2016 Total Scan time: 3.690 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]