FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5447, 413 aa
  1>>>pF1KB5447 413 - 413 aa - 413 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9360+/-0.000407; mu= 18.8688+/- 0.025
 mean_var=59.1917+/-12.013, 0's: 0 Z-trim(111.2): 23  B-trim: 0 in 0/54
 Lambda= 0.166703
 statistics sampled from 19669 (19684) to 19669 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.231), width:  16
 Scan time:  7.270

The best scores are:                                      opt bits E(85289)
NP_002070 (OMIM: 138180,614419) aspartate aminotra ( 413) 2781 677.5 1.7e-194
NP_002071 (OMIM: 138150) aspartate aminotransferas ( 430) 1323 326.8 6.2e-89
NP_001273149 (OMIM: 138150) aspartate aminotransfe ( 387) 1075 267.2 5.1e-71


>>NP_002070 (OMIM: 138180,614419) aspartate aminotransfe  (413 aa)
 initn: 2781 init1: 2781 opt: 2781  Z-score: 3612.9  bits: 677.5 E(85289): 1.7e-194
Smith-Waterman score: 2781; 100.0% identity (100.0% similar) in 413 aa overlap (1-413:1-413)

               10        20        30        40        50        60
pF1KB5 MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 IANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLEN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 APEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 APEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 IRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 AQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGM
              310       320       330       340       350       360

              370       380       390       400       410   
pF1KB5 FSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ
              370       380       390       400       410   

>>NP_002071 (OMIM: 138150) aspartate aminotransferase, m  (430 aa)
 initn: 1293 init1: 914 opt: 1323  Z-score: 1717.6  bits: 326.8 E(85289): 6.2e-89
Smith-Waterman score: 1323; 48.9% identity (78.1% similar) in 407 aa overlap (5-411:31-430)

                                         10        20        30    
pF1KB5                           MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKV
                                     : ...: .. :  .. .:  :..: . .:.
NP_002 MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKM
               10        20        30        40        50        60

           40        50        60        70        80        90    
pF1KB5 NLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDDSP
       :::::::: :. .:.::: :.:.: .::  : :..::::: ::::: . ...::::..: 
NP_002 NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKN-LDKEYLPIGGLAEFCKASAELALGENSE
               70        80        90        100       110         

          100       110       120       130       140       150    
pF1KB5 ALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFK
       .::  :   ::...:::::::::.:: :... . .    :.. .::: ::. .:  ::..
NP_002 VLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRD----VFLPKPTWGNHTPIFRDAGMQ
     120       130       140       150           160       170     

          160       170       180       190       200       210    
pF1KB5 DIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMK
        ...:::.: .  :.:. : ..:. . :: :...::::::::::.:: :::::.::.:.:
NP_002 -LQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVK
          180       190       200       210       220       230    

          220       230       240       250       260       270    
pF1KB5 HRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVV
       .: :: ::: ::::::::. ..::::.:.:. .:..    ::..::.:::.:::: .:.:
NP_002 KRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMV
          240       250       260       270       280       290    

          280       290       300       310       320       330    
pF1KB5 GKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTM
        :. .   .: ::.. ..:  .:::: .::::.:. :..:.: ..:  .::.:::::. :
NP_002 CKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGM
          300       310       320       330       340       350    

          340       350       360       370       380       390    
pF1KB5 RSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLT
       :..: . :.   .  .:.::::::::: ::::.:.::: :..:  ::.  .:::.:.:.:
NP_002 RTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVT
          360       370       380       390       400       410    

          400       410   
pF1KB5 TKNLDYVATSIHEAVTKIQ
       ..:. :.: .::. :::  
NP_002 SSNVGYLAHAIHQ-VTK  
          420        430  

>>NP_001273149 (OMIM: 138150) aspartate aminotransferase  (387 aa)
 initn: 1165 init1: 914 opt: 1075  Z-score: 1395.9  bits: 267.2 E(85289): 5.1e-71
Smith-Waterman score: 1107; 43.5% identity (70.3% similar) in 407 aa overlap (5-411:31-387)

                                         10        20        30    
pF1KB5                           MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKV
                                     : ...: .. :  .. .:  :..: . .:.
NP_001 MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKM
               10        20        30        40        50        60

           40        50        60        70        80        90    
pF1KB5 NLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDDSP
       :::::::: :. .:.::: :.:                       : .            
NP_001 NLGVGAYRDDNGKPYVLPSVRK-----------------------FVT------------
               70        80                                        

          100       110       120       130       140       150    
pF1KB5 ALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFK
                ::...:::::::::.:: :... . .    :.. .::: ::. .:  ::..
NP_001 ---------VQTISGTGALRIGASFLQRFFKFSRD----VFLPKPTWGNHTPIFRDAGMQ
                   90       100       110           120       130  

          160       170       180       190       200       210    
pF1KB5 DIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMK
        ...:::.: .  :.:. : ..:. . :: :...::::::::::.:: :::::.::.:.:
NP_001 -LQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVK
             140       150       160       170       180       190 

          220       230       240       250       260       270    
pF1KB5 HRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVV
       .: :: ::: ::::::::. ..::::.:.:. .:..    ::..::.:::.:::: .:.:
NP_001 KRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMV
             200       210       220       230       240       250 

          280       290       300       310       320       330    
pF1KB5 GKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTM
        :. .   .: ::.. ..:  .:::: .::::.:. :..:.: ..:  .::.:::::. :
NP_001 CKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGM
             260       270       280       290       300       310 

          340       350       360       370       380       390    
pF1KB5 RSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLT
       :..: . :.   .  .:.::::::::: ::::.:.::: :..:  ::.  .:::.:.:.:
NP_001 RTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVT
             320       330       340       350       360       370 

          400       410   
pF1KB5 TKNLDYVATSIHEAVTKIQ
       ..:. :.: .::. :::  
NP_001 SSNVGYLAHAIHQ-VTK  
             380          




413 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:39:35 2016 done: Sat Nov  5 19:39:36 2016
 Total Scan time:  7.270 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]