FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5451, 372 aa 1>>>pF1KB5451 372 - 372 aa - 372 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1025+/-0.000364; mu= 8.8918+/- 0.023 mean_var=124.2868+/-24.543, 0's: 0 Z-trim(117.7): 65 B-trim: 652 in 1/56 Lambda= 0.115043 statistics sampled from 29872 (29937) to 29872 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.351), width: 16 Scan time: 7.500 The best scores are: opt bits E(85289) NP_061119 (OMIM: 616141) core histone macro-H2A.2 ( 372) 2370 404.3 2.3e-112 NP_613258 (OMIM: 610054) core histone macro-H2A.1 ( 372) 1639 283.0 7.6e-76 XP_011542031 (OMIM: 610054) PREDICTED: core histon ( 372) 1639 283.0 7.6e-76 XP_011542032 (OMIM: 610054) PREDICTED: core histon ( 371) 1634 282.2 1.3e-75 NP_004884 (OMIM: 610054) core histone macro-H2A.1 ( 371) 1634 282.2 1.3e-75 NP_001035248 (OMIM: 610054) core histone macro-H2A ( 371) 1634 282.2 1.3e-75 NP_613075 (OMIM: 610054) core histone macro-H2A.1 ( 369) 1587 274.4 3e-73 XP_005272189 (OMIM: 610054) PREDICTED: core histon ( 368) 1582 273.5 5.3e-73 XP_011542033 (OMIM: 610054) PREDICTED: core histon ( 270) 1119 196.6 5.6e-50 XP_011542034 (OMIM: 610054) PREDICTED: core histon ( 269) 1114 195.8 9.9e-50 XP_016865557 (OMIM: 610054) PREDICTED: core histon ( 235) 976 172.8 7e-43 XP_011542035 (OMIM: 610054) PREDICTED: core histon ( 252) 924 164.2 2.9e-40 XP_016865556 (OMIM: 610054) PREDICTED: core histon ( 251) 919 163.4 5.2e-40 XP_011542036 (OMIM: 610054) PREDICTED: core histon ( 196) 866 154.5 1.9e-37 XP_005272191 (OMIM: 610054) PREDICTED: core histon ( 199) 866 154.5 1.9e-37 XP_011542037 (OMIM: 610054) PREDICTED: core histon ( 195) 861 153.7 3.3e-37 XP_005272192 (OMIM: 610054) PREDICTED: core histon ( 198) 861 153.7 3.4e-37 XP_016865558 (OMIM: 610054) PREDICTED: core histon ( 222) 861 153.7 3.7e-37 NP_002096 (OMIM: 601772) histone H2AX [Homo sapien ( 143) 503 94.2 2e-19 NP_778235 (OMIM: 615014) histone H2A type 2-B [Hom ( 130) 493 92.5 5.8e-19 NP_734466 (OMIM: 613499) histone H2A type 1-A [Hom ( 131) 491 92.2 7.4e-19 NP_003508 (OMIM: 602797) histone H2A type 2-C [Hom ( 129) 490 92.0 8.2e-19 NP_003507 (OMIM: 142720) histone H2A type 2-A [Hom ( 130) 490 92.0 8.2e-19 NP_254280 (OMIM: 615015) histone H2A type 3 [Homo ( 130) 486 91.4 1.3e-18 NP_003503 (OMIM: 602794) histone H2A type 1-C [Hom ( 130) 485 91.2 1.5e-18 NP_066544 (OMIM: 602791) histone cluster 1, H2aj [ ( 128) 484 91.0 1.6e-18 NP_066409 (OMIM: 602792) histone H2A type 1-D [Hom ( 130) 484 91.0 1.6e-18 NP_542163 (OMIM: 615013) histone H2A type 1-H [Hom ( 128) 483 90.9 1.8e-18 NP_003500 (OMIM: 602787) histone H2A type 1 [Homo ( 130) 483 90.9 1.8e-18 NP_066408 (OMIM: 615012) histone H2A type 1 [Homo ( 130) 483 90.9 1.8e-18 NP_066390 (OMIM: 602786) histone H2A type 1-B/E [H ( 130) 483 90.9 1.8e-18 NP_003501 (OMIM: 602788) histone H2A type 1 [Homo ( 130) 483 90.9 1.8e-18 NP_003502 (OMIM: 602793) histone H2A type 1 [Homo ( 130) 483 90.9 1.8e-18 NP_003505 (OMIM: 602796) histone H2A type 1 [Homo ( 130) 483 90.9 1.8e-18 NP_003504 (OMIM: 602795) histone H2A type 1-B/E [H ( 130) 483 90.9 1.8e-18 NP_002097 (OMIM: 142763) histone H2A.Z [Homo sapie ( 128) 393 75.9 5.7e-14 NP_542451 (OMIM: 300445) histone H2A-Bbd type 2/3 ( 115) 236 49.8 3.7e-06 XP_011511231 (OMIM: 610028) PREDICTED: poly [ADP-r (1209) 214 46.8 0.00031 XP_011511230 (OMIM: 610028) PREDICTED: poly [ADP-r (1719) 214 46.9 0.00042 NP_060024 (OMIM: 610028) poly [ADP-ribose] polymer (1801) 214 46.9 0.00043 XP_011510782 (OMIM: 612066) PREDICTED: poly [ADP-r ( 355) 189 42.3 0.002 XP_011510778 (OMIM: 612066) PREDICTED: poly [ADP-r ( 628) 191 42.8 0.0026 XP_005247216 (OMIM: 612066) PREDICTED: poly [ADP-r ( 609) 189 42.5 0.0032 NP_001106995 (OMIM: 612066) poly [ADP-ribose] poly ( 678) 189 42.5 0.0035 >>NP_061119 (OMIM: 616141) core histone macro-H2A.2 [Hom (372 aa) initn: 2370 init1: 2370 opt: 2370 Z-score: 2138.3 bits: 404.3 E(85289): 2.3e-112 Smith-Waterman score: 2370; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG 310 320 330 340 350 360 370 pF1KB5 IYVQEMAKLDAK :::::::::::: NP_061 IYVQEMAKLDAK 370 >>NP_613258 (OMIM: 610054) core histone macro-H2A.1 isof (372 aa) initn: 1639 init1: 1639 opt: 1639 Z-score: 1482.6 bits: 283.0 E(85289): 7.6e-76 Smith-Waterman score: 1639; 67.9% identity (89.2% similar) in 371 aa overlap (1-371:1-371) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: NP_613 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. NP_613 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.... .. : .::. . : ..:.: . .: ....::.: :. NP_613 KGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::.: .:.::......::.:..::.:.::::.:.:..::: :::: NP_613 DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: :::: . :: :::::::. : ::.::::: ::.:.::::. NP_613 FVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG :.::::::.::: . :::: ::::::::. :::::..: .. .::.:.:::.:::::::: NP_613 ADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIG 310 320 330 340 350 360 370 pF1KB5 IYVQEMAKLDAK ::::::::::: NP_613 IYVQEMAKLDAN 370 >>XP_011542031 (OMIM: 610054) PREDICTED: core histone ma (372 aa) initn: 1639 init1: 1639 opt: 1639 Z-score: 1482.6 bits: 283.0 E(85289): 7.6e-76 Smith-Waterman score: 1639; 67.9% identity (89.2% similar) in 371 aa overlap (1-371:1-371) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: XP_011 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. XP_011 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.... .. : .::. . : ..:.: . .: ....::.: :. XP_011 KGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::.: .:.::......::.:..::.:.::::.:.:..::: :::: XP_011 DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: :::: . :: :::::::. : ::.::::: ::.:.::::. XP_011 FVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG :.::::::.::: . :::: ::::::::. :::::..: .. .::.:.:::.:::::::: XP_011 ADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIG 310 320 330 340 350 360 370 pF1KB5 IYVQEMAKLDAK ::::::::::: XP_011 IYVQEMAKLDAN 370 >>XP_011542032 (OMIM: 610054) PREDICTED: core histone ma (371 aa) initn: 941 init1: 941 opt: 1634 Z-score: 1478.2 bits: 282.2 E(85289): 1.3e-75 Smith-Waterman score: 1634; 68.5% identity (89.2% similar) in 371 aa overlap (1-371:1-370) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: XP_011 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. XP_011 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.. :. : :: .:. ..: . :..: . .: ....::.: :. XP_011 KGKLEAIITPPPAKKA-KSPSQKKPVSKKAGGKKGARKSKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::.: .:.::......::.:..::.:.::::.:.:..::: :::: XP_011 DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: :::: . :: :::::::. : ::.::::: ::.:.::::. XP_011 FVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG :.::::::.::: . :::: ::::::::. :::::..: .. .::.:.:::.:::::::: XP_011 ADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIG 300 310 320 330 340 350 370 pF1KB5 IYVQEMAKLDAK ::::::::::: XP_011 IYVQEMAKLDAN 360 370 >>NP_004884 (OMIM: 610054) core histone macro-H2A.1 isof (371 aa) initn: 941 init1: 941 opt: 1634 Z-score: 1478.2 bits: 282.2 E(85289): 1.3e-75 Smith-Waterman score: 1634; 68.5% identity (89.2% similar) in 371 aa overlap (1-371:1-370) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: NP_004 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. NP_004 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.. :. : :: .:. ..: . :..: . .: ....::.: :. NP_004 KGKLEAIITPPPAKKA-KSPSQKKPVSKKAGGKKGARKSKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::.: .:.::......::.:..::.:.::::.:.:..::: :::: NP_004 DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: :::: . :: :::::::. : ::.::::: ::.:.::::. NP_004 FVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG :.::::::.::: . :::: ::::::::. :::::..: .. .::.:.:::.:::::::: NP_004 ADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIG 300 310 320 330 340 350 370 pF1KB5 IYVQEMAKLDAK ::::::::::: NP_004 IYVQEMAKLDAN 360 370 >>NP_001035248 (OMIM: 610054) core histone macro-H2A.1 i (371 aa) initn: 941 init1: 941 opt: 1634 Z-score: 1478.2 bits: 282.2 E(85289): 1.3e-75 Smith-Waterman score: 1634; 68.5% identity (89.2% similar) in 371 aa overlap (1-371:1-370) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: NP_001 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. NP_001 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.. :. : :: .:. ..: . :..: . .: ....::.: :. NP_001 KGKLEAIITPPPAKKA-KSPSQKKPVSKKAGGKKGARKSKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::.: .:.::......::.:..::.:.::::.:.:..::: :::: NP_001 DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: :::: . :: :::::::. : ::.::::: ::.:.::::. NP_001 FVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG :.::::::.::: . :::: ::::::::. :::::..: .. .::.:.:::.:::::::: NP_001 ADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIG 300 310 320 330 340 350 370 pF1KB5 IYVQEMAKLDAK ::::::::::: NP_001 IYVQEMAKLDAN 360 370 >>NP_613075 (OMIM: 610054) core histone macro-H2A.1 isof (369 aa) initn: 902 init1: 902 opt: 1587 Z-score: 1436.1 bits: 274.4 E(85289): 3e-73 Smith-Waterman score: 1587; 66.3% identity (87.3% similar) in 371 aa overlap (1-371:1-368) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: NP_613 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. NP_613 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.... .. : .::. . : ..:.: . .: ....::.: :. NP_613 KGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::...:.::. : : ...::::.... . ..:..::: :::: NP_613 DGFTVLSTKSLFLGQKLQVVQADIASIDS---DAVVHPTNTDFYIGGEVGNTLEKKGGKE 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: :::: . :: :::::::. : ::.::::: ::.:.::::. NP_613 FVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG :.::::::.::: . :::: ::::::::. :::::..: .. .::.:.:::.:::::::: NP_613 ADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIG 300 310 320 330 340 350 370 pF1KB5 IYVQEMAKLDAK ::::::::::: NP_613 IYVQEMAKLDAN 360 >>XP_005272189 (OMIM: 610054) PREDICTED: core histone ma (368 aa) initn: 1444 init1: 749 opt: 1582 Z-score: 1431.6 bits: 273.5 E(85289): 5.3e-73 Smith-Waterman score: 1582; 66.8% identity (87.3% similar) in 371 aa overlap (1-371:1-367) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: XP_005 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. XP_005 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.. :. : :: .:. ..: . :..: . .: ....::.: :. XP_005 KGKLEAIITPPPAKKA-KSPSQKKPVSKKAGGKKGARKSKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::...:.::. : : ...::::.... . ..:..::: :::: XP_005 DGFTVLSTKSLFLGQKLQVVQADIASIDS---DAVVHPTNTDFYIGGEVGNTLEKKGGKE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: :::: . :: :::::::. : ::.::::: ::.:.::::. XP_005 FVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 AEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIG :.::::::.::: . :::: ::::::::. :::::..: .. .::.:.:::.:::::::: XP_005 ADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIG 300 310 320 330 340 350 370 pF1KB5 IYVQEMAKLDAK ::::::::::: XP_005 IYVQEMAKLDAN 360 >>XP_011542033 (OMIM: 610054) PREDICTED: core histone ma (270 aa) initn: 1119 init1: 1119 opt: 1119 Z-score: 1018.3 bits: 196.6 E(85289): 5.6e-50 Smith-Waterman score: 1119; 65.7% identity (89.4% similar) in 265 aa overlap (1-265:1-265) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: XP_011 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. XP_011 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.... .. : .::. . : ..:.: . .: ....::.: :. XP_011 KGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::.: .:.::......::.:..::.:.::::.:.:..::: :::: XP_011 DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: ..: :: XP_011 FVEAVLELRKKNGPLEVAGGTVFQSRQQLS 250 260 270 >>XP_011542034 (OMIM: 610054) PREDICTED: core histone ma (269 aa) initn: 818 init1: 741 opt: 1114 Z-score: 1013.8 bits: 195.8 E(85289): 9.9e-50 Smith-Waterman score: 1114; 66.4% identity (89.4% similar) in 265 aa overlap (1-265:1-264) 10 20 30 40 50 60 pF1KB5 MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEI ::.:.:::: .: ::::.:::::::::..::.::: ::::.::::::::::.:::.::: XP_011 MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGT :::::::::::::.:..:::::::::::::::::::::::::::::: :::::::::::. XP_011 LELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPG ::: :.:..::: :.. :. : :: .:. ..: . :..: . .: ....::.: :. XP_011 KGKLEAIITPPPAKKA-KSPSQKKPVSKKAGGKKGARKSKKQGEVSKAASADSTTEGTPA 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 DGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKE ::::.::.::: :::::.: .:.::......::.:..::.:.::::.:.:..::: :::: XP_011 DGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 FLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSA :.:.: ::::..:::::: ..: :: XP_011 FVEAVLELRKKNGPLEVAGGTVFQSRQQLS 240 250 260 372 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:49:15 2016 done: Sat Nov 5 12:49:16 2016 Total Scan time: 7.500 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]