FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5457, 483 aa 1>>>pF1KB5457 483 - 483 aa - 483 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7874+/-0.000385; mu= 21.0737+/- 0.024 mean_var=64.7020+/-13.637, 0's: 0 Z-trim(111.3): 23 B-trim: 1109 in 1/53 Lambda= 0.159447 statistics sampled from 19787 (19805) to 19787 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.232), width: 16 Scan time: 8.950 The best scores are: opt bits E(85289) NP_002622 (OMIM: 172200) 6-phosphogluconate dehydr ( 483) 3245 755.6 7.1e-218 NP_001291381 (OMIM: 172200) 6-phosphogluconate deh ( 470) 3170 738.3 1.1e-212 NP_001291380 (OMIM: 172200) 6-phosphogluconate deh ( 461) 2556 597.1 3.5e-170 >>NP_002622 (OMIM: 172200) 6-phosphogluconate dehydrogen (483 aa) initn: 3245 init1: 3245 opt: 3245 Z-score: 4032.6 bits: 755.6 E(85289): 7.1e-218 Smith-Waterman score: 3245; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483) 10 20 30 40 50 60 pF1KB5 MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS 430 440 450 460 470 480 pF1KB5 YNA ::: NP_002 YNA >>NP_001291381 (OMIM: 172200) 6-phosphogluconate dehydro (470 aa) initn: 3170 init1: 3170 opt: 3170 Z-score: 3939.5 bits: 738.3 E(85289): 1.1e-212 Smith-Waterman score: 3170; 100.0% identity (100.0% similar) in 470 aa overlap (14-483:1-470) 10 20 30 40 50 60 pF1KB5 MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE 10 20 30 40 70 80 90 100 110 120 pF1KB5 MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS 410 420 430 440 450 460 pF1KB5 YNA ::: NP_001 YNA 470 >>NP_001291380 (OMIM: 172200) 6-phosphogluconate dehydro (461 aa) initn: 2553 init1: 2553 opt: 2556 Z-score: 3176.3 bits: 597.1 E(85289): 3.5e-170 Smith-Waterman score: 3047; 95.4% identity (95.4% similar) in 483 aa overlap (1-483:1-461) 10 20 30 40 50 60 pF1KB5 MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG :::::::::::::::::::::::::::: :::::::::: NP_001 MVSKLKKPRRIILLVKAGQAVDDFIEKL----------------------RRCRDLKAKG 70 80 90 130 140 150 160 170 180 pF1KB5 ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB5 PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS 400 410 420 430 440 450 pF1KB5 YNA ::: NP_001 YNA 460 483 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:46:47 2016 done: Fri Nov 4 03:46:48 2016 Total Scan time: 8.950 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]