FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5462, 376 aa 1>>>pF1KB5462 376 - 376 aa - 376 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0460+/-0.000432; mu= 17.9781+/- 0.027 mean_var=60.2859+/-11.992, 0's: 0 Z-trim(109.3): 39 B-trim: 56 in 1/52 Lambda= 0.165183 statistics sampled from 17452 (17491) to 17452 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.205), width: 16 Scan time: 8.010 The best scores are: opt bits E(85289) NP_005726 (OMIM: 605144) beta-centractin [Homo sap ( 376) 2486 601.2 1.2e-171 NP_005727 (OMIM: 605143) alpha-centractin [Homo sa ( 376) 2344 567.4 1.9e-161 XP_016858605 (OMIM: 605144) PREDICTED: beta-centra ( 332) 2176 527.3 1.9e-149 XP_005263911 (OMIM: 605144) PREDICTED: beta-centra ( 302) 1976 479.7 3.9e-135 NP_005150 (OMIM: 102540,612098,612794,613424) acti ( 377) 1451 354.6 2.2e-97 NP_001186883 (OMIM: 102560,604717,614583) actin, c ( 375) 1448 353.9 3.6e-97 NP_001605 (OMIM: 102560,604717,614583) actin, cyto ( 375) 1448 353.9 3.6e-97 NP_001092 (OMIM: 102630,243310,607371,608578) acti ( 375) 1448 353.9 3.6e-97 NP_001091 (OMIM: 102610,161800,255310,616852) acti ( 377) 1446 353.4 5e-97 NP_001135417 (OMIM: 102620,611788,613834,614042) a ( 377) 1443 352.7 8.1e-97 NP_001604 (OMIM: 102620,611788,613834,614042) acti ( 377) 1443 352.7 8.1e-97 NP_001307784 (OMIM: 102620,611788,613834,614042) a ( 377) 1443 352.7 8.1e-97 NP_001606 (OMIM: 102545) actin, gamma-enteric smoo ( 376) 1440 352.0 1.3e-96 NP_001017992 (OMIM: 614835) beta-actin-like protei ( 376) 1425 348.4 1.6e-95 XP_016859649 (OMIM: 608914) PREDICTED: POTE ankyri ( 657) 1366 334.5 4.3e-91 XP_011509518 (OMIM: 608914) PREDICTED: POTE ankyri ( 957) 1366 334.6 5.9e-91 XP_016859648 (OMIM: 608914) PREDICTED: POTE ankyri ( 967) 1366 334.6 6e-91 XP_016859650 (OMIM: 608914) PREDICTED: POTE ankyri (1075) 1366 334.6 6.5e-91 NP_001077007 (OMIM: 608914) POTE ankyrin domain fa (1075) 1366 334.6 6.5e-91 NP_001186822 (OMIM: 102545) actin, gamma-enteric s ( 333) 1119 275.5 1.3e-73 NP_115876 (OMIM: 608534) actin-related protein T3 ( 372) 1069 263.6 5.4e-70 NP_536356 (OMIM: 608535) actin-related protein T2 ( 377) 1046 258.1 2.5e-68 NP_612146 (OMIM: 300487) actin-related protein T1 ( 376) 1014 250.5 4.8e-66 NP_005713 (OMIM: 604221) actin-related protein 2 i ( 394) 1012 250.0 7e-66 NP_001005386 (OMIM: 604221) actin-related protein ( 399) 1001 247.4 4.4e-65 NP_006677 (OMIM: 604304) actin-like protein 7B [Ho ( 415) 940 232.8 1.1e-60 NP_006678 (OMIM: 604303) actin-like protein 7A [Ho ( 435) 930 230.5 5.8e-60 NP_005712 (OMIM: 604222) actin-related protein 3 i ( 418) 497 127.3 6.5e-29 NP_001264069 (OMIM: 604222) actin-related protein ( 367) 477 122.5 1.6e-27 NP_057272 (OMIM: 612458) actin-like protein 6B [Ho ( 426) 416 108.0 4.3e-23 NP_829888 (OMIM: 604958) actin-like protein 6A iso ( 387) 342 90.3 8e-18 NP_817126 (OMIM: 604958) actin-like protein 6A iso ( 387) 342 90.3 8e-18 NP_004292 (OMIM: 604958) actin-like protein 6A iso ( 429) 342 90.3 8.7e-18 >>NP_005726 (OMIM: 605144) beta-centractin [Homo sapiens (376 aa) initn: 2486 init1: 2486 opt: 2486 Z-score: 3202.5 bits: 601.2 E(85289): 1.2e-171 Smith-Waterman score: 2486; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB5 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSK 310 320 330 340 350 360 370 pF1KB5 KEYEEDGSRAIHRKTF :::::::::::::::: NP_005 KEYEEDGSRAIHRKTF 370 >>NP_005727 (OMIM: 605143) alpha-centractin [Homo sapien (376 aa) initn: 2344 init1: 2344 opt: 2344 Z-score: 3019.6 bits: 567.4 E(85289): 1.9e-161 Smith-Waterman score: 2344; 90.4% identity (98.9% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB5 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP :::::.::::::::::::::::::::::::::::::::::::::.::::::::::.:::: NP_005 MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN :::::::::.::::::::.:.:::::::::::::::::::::::::::::::::::: :: NP_005 KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQ ::.:::::::::.::: ::::: :::.:.:::.:..::::::::::::::::.:::::.: NP_005 MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVL : ::::::...::.:::::::::.:::.:.::::.:::..:::.:::::::::::.:::: NP_005 YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSK :::::::::::::::::::::::::.::.::::::::::::::::::::::::::::::: NP_005 SGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSK 310 320 330 340 350 360 370 pF1KB5 KEYEEDGSRAIHRKTF :::::::.:.:::::: NP_005 KEYEEDGARSIHRKTF 370 >>XP_016858605 (OMIM: 605144) PREDICTED: beta-centractin (332 aa) initn: 2176 init1: 2176 opt: 2176 Z-score: 2804.0 bits: 527.3 E(85289): 1.9e-149 Smith-Waterman score: 2176; 100.0% identity (100.0% similar) in 332 aa overlap (45-376:1-332) 20 30 40 50 60 70 pF1KB5 DNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYP :::::::::::::::::::::::::::::: XP_016 MRVMAGALEGDLFIGPKAEEHRGLLTIRYP 10 20 30 80 90 100 110 120 130 pF1KB5 MEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNV 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB5 PALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYL 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB5 RLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPDGSTLDVGPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPDGSTLDVGPA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB5 RFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRL 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB5 LSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRK 280 290 300 310 320 330 pF1KB5 TF :: XP_016 TF >>XP_005263911 (OMIM: 605144) PREDICTED: beta-centractin (302 aa) initn: 1976 init1: 1976 opt: 1976 Z-score: 2547.0 bits: 479.7 E(85289): 3.9e-135 Smith-Waterman score: 1976; 100.0% identity (100.0% similar) in 302 aa overlap (75-376:1-302) 50 60 70 80 90 100 pF1KB5 MRVMAGALEGDLFIGPKAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSE :::::::::::::::::::::::::::::: XP_005 MEHGVVRDWNDMERIWQYVYSKDQLQTFSE 10 20 30 110 120 130 140 150 160 pF1KB5 EHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 THAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 SINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIH 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 KSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGG 220 230 240 250 260 270 350 360 370 pF1KB5 SILASLDTFKKMWVSKKEYEEDGSRAIHRKTF :::::::::::::::::::::::::::::::: XP_005 SILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 280 290 300 >>NP_005150 (OMIM: 102540,612098,612794,613424) actin, a (377 aa) initn: 1442 init1: 582 opt: 1451 Z-score: 1869.4 bits: 354.6 E(85289): 2.2e-97 Smith-Waterman score: 1451; 54.9% identity (82.2% similar) in 370 aa overlap (12-376:10-377) 10 20 30 40 50 60 pF1KB5 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP .: :::::..:::::::. :. ::. ::::.:. ::.: . : ..: NP_005 MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN .:. .::.::..::.:::.. .:.:::.::.... ..:.. ::::.:::::::::. : NP_005 EAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFY-NELRVAPEEHPTLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::: ....::::::::.....::::::::.:::::.:::::::::: ::::::.:.::.: NP_005 REKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALET---- ::.:.::::.. :: .: ..: .: :.:: :.:: :::. ::.... ... : . NP_005 MRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 -EKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLF :: .: ::::... .: ::: :: ::::...: :: :.::.. .: : :.:.:. :. NP_005 LEK-SYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKK :: :::::.:.. :..::. .:. :::. .:::: :: :: ::.::::::::::.::.. NP_005 ANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ 300 310 320 330 340 350 360 370 pF1KB5 MWVSKKEYEEDGSRAIHRKTF ::.::.::.: : .::: : NP_005 MWISKQEYDEAGPSIVHRKCF 360 370 >>NP_001186883 (OMIM: 102560,604717,614583) actin, cytop (375 aa) initn: 1442 init1: 581 opt: 1448 Z-score: 1865.6 bits: 353.9 E(85289): 3.6e-97 Smith-Waterman score: 1448; 54.9% identity (82.7% similar) in 370 aa overlap (12-376:8-375) 10 20 30 40 50 60 pF1KB5 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP .:::::::. :::::::. :. ::. ::::.:. ::.: . : ..: NP_001 MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN .:. .::.::..::.:::.: .:.:::.::.... ..:.. ::::::::::::::. : NP_001 EAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFY-NELRVAPEEHPVLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::: ....:::::.::.....::::::::.:::::.:.::::::::.::::::.:.::.: NP_001 REKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALET---- .:.:.::::.. :: .: ..: .: :.:: :.:: :::. ::.... ... : . NP_001 LRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 -EKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLF :: .: ::::... .: ::: :: ::::...: :: :.::.. .: : :.:.:. :. NP_001 LEK-SYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKK :: :::::.:.. :..::. .:. :::. .:::: :: :: ::.::::::::::.::.. NP_001 ANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ 300 310 320 330 340 350 360 370 pF1KB5 MWVSKKEYEEDGSRAIHRKTF ::.::.::.:.: .::: : NP_001 MWISKQEYDESGPSIVHRKCF 360 370 >>NP_001605 (OMIM: 102560,604717,614583) actin, cytoplas (375 aa) initn: 1442 init1: 581 opt: 1448 Z-score: 1865.6 bits: 353.9 E(85289): 3.6e-97 Smith-Waterman score: 1448; 54.9% identity (82.7% similar) in 370 aa overlap (12-376:8-375) 10 20 30 40 50 60 pF1KB5 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP .:::::::. :::::::. :. ::. ::::.:. ::.: . : ..: NP_001 MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN .:. .::.::..::.:::.: .:.:::.::.... ..:.. ::::::::::::::. : NP_001 EAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFY-NELRVAPEEHPVLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::: ....:::::.::.....::::::::.:::::.:.::::::::.::::::.:.::.: NP_001 REKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALET---- .:.:.::::.. :: .: ..: .: :.:: :.:: :::. ::.... ... : . NP_001 LRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 -EKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLF :: .: ::::... .: ::: :: ::::...: :: :.::.. .: : :.:.:. :. NP_001 LEK-SYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKK :: :::::.:.. :..::. .:. :::. .:::: :: :: ::.::::::::::.::.. NP_001 ANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ 300 310 320 330 340 350 360 370 pF1KB5 MWVSKKEYEEDGSRAIHRKTF ::.::.::.:.: .::: : NP_001 MWISKQEYDESGPSIVHRKCF 360 370 >>NP_001092 (OMIM: 102630,243310,607371,608578) actin, c (375 aa) initn: 1432 init1: 581 opt: 1448 Z-score: 1865.6 bits: 353.9 E(85289): 3.6e-97 Smith-Waterman score: 1448; 54.4% identity (82.0% similar) in 377 aa overlap (5-376:4-375) 10 20 30 40 50 60 pF1KB5 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP :: : .:.:::::. :::::::. :. ::. ::::.:. ::.: . : ..: NP_001 MDDDIAA---LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN .:. .::.::..::.:::.: .:.:::.::.... ..:.. ::::::::::::::. : NP_001 EAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFY-NELRVAPEEHPVLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::: ....:::::.::.....::::::::.:::::.:.::::::::.::::::.:.::.: NP_001 REKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALET---- .:.:.::::.. :: .: ..: .: :.:: :.:: :::. ::.... ... : . NP_001 LRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 -EKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLF :: .: ::::... .: ::: :: ::::...: :: :.::.. .: : :.:.:. :. NP_001 LEK-SYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKK :: :::::.:.. :..::. .:. :::. .:::: :: :: ::.::::::::::.::.. NP_001 ANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ 300 310 320 330 340 350 360 370 pF1KB5 MWVSKKEYEEDGSRAIHRKTF ::.::.::.:.: .::: : NP_001 MWISKQEYDESGPSIVHRKCF 360 370 >>NP_001091 (OMIM: 102610,161800,255310,616852) actin, a (377 aa) initn: 1437 init1: 582 opt: 1446 Z-score: 1863.0 bits: 353.4 E(85289): 5e-97 Smith-Waterman score: 1446; 54.3% identity (82.2% similar) in 370 aa overlap (12-376:10-377) 10 20 30 40 50 60 pF1KB5 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP .: :::::..:::::::. :. ::. ::::.:. ::.: . : ..: NP_001 MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN .:. .::.::..::.:::.. .:.:::.::.... ..:.. ::::.:::::::::. : NP_001 EAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFY-NELRVAPEEHPTLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::: ....::::::::.....::::::::.:::::.:::::::::: ::::::.:.::.: NP_001 REKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALET---- ::.:.::::.. :: .: ..: .: :.:: :.:: :::. ::.... ... : . NP_001 MRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 -EKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLF :: .: ::::... .: ::: :: ::::...: :: :.::.. .: : :.:.:. :. NP_001 LEK-SYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKK :: :.:::.:.. :..::. .:. :::. .:::: :: :: ::.::::::::::.::.. NP_001 ANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ 300 310 320 330 340 350 360 370 pF1KB5 MWVSKKEYEEDGSRAIHRKTF ::..:.::.: : .::: : NP_001 MWITKQEYDEAGPSIVHRKCF 360 370 >>NP_001135417 (OMIM: 102620,611788,613834,614042) actin (377 aa) initn: 1434 init1: 582 opt: 1443 Z-score: 1859.1 bits: 352.7 E(85289): 8.1e-97 Smith-Waterman score: 1443; 54.9% identity (81.6% similar) in 370 aa overlap (12-376:10-377) 10 20 30 40 50 60 pF1KB5 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP .: :::::. :::::::. :. ::. ::::.:. ::.: . : ..: NP_001 MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN .:. .::.::..::.:::.. .:.:::.::.. . ..:.. ::::.:::::::::. : NP_001 EAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFY-NELRVAPEEHPTLLTEAPLNPKAN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI ::: ....::::::::.....::::::::.:::::.:::::::::: ::::::.:.::.: NP_001 REKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAI 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALET---- ::.:.::::.. :: .: ..: .: :.:: :.:: :::. ::.... ... : . NP_001 MRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 -EKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLF :: .: ::::... .: ::: :: ::::...: :: :.::.. .: : :.:.:. :. NP_001 LEK-SYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 ANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKK :: :::::.:.. :..::. .:. :::. .:::: :: :: ::.::::::::::.::.. NP_001 ANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ 300 310 320 330 340 350 360 370 pF1KB5 MWVSKKEYEEDGSRAIHRKTF ::.::.::.: : .::: : NP_001 MWISKQEYDEAGPSIVHRKCF 360 370 376 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:51:05 2016 done: Sat Nov 5 12:51:06 2016 Total Scan time: 8.010 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]