FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5463, 288 aa 1>>>pF1KB5463 288 - 288 aa - 288 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5749+/-0.000537; mu= 6.1762+/- 0.033 mean_var=179.7399+/-35.041, 0's: 0 Z-trim(113.3): 63 B-trim: 37 in 1/53 Lambda= 0.095665 statistics sampled from 22477 (22537) to 22477 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.264), width: 16 Scan time: 5.210 The best scores are: opt bits E(85289) NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Ho ( 288) 1803 261.2 1.7e-69 NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo ( 288) 1543 225.3 1.1e-58 XP_016878382 (OMIM: 601485,616172) PREDICTED: synt ( 282) 1483 217.0 3.3e-56 NP_001159375 (OMIM: 186590) syntaxin-1A isoform 2 ( 251) 1413 207.3 2.5e-53 XP_016868056 (OMIM: 186590) PREDICTED: syntaxin-1A ( 329) 1413 207.4 3e-53 XP_005274255 (OMIM: 600876) PREDICTED: syntaxin-3 ( 287) 1227 181.7 1.5e-45 XP_016873682 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 1203 178.3 1.4e-44 XP_016873681 (OMIM: 600876) PREDICTED: syntaxin-3 ( 279) 1203 178.3 1.4e-44 NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Hom ( 287) 1200 177.9 1.9e-44 NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Hom ( 288) 1188 176.3 6.1e-44 XP_016874469 (OMIM: 132350) PREDICTED: syntaxin-2 ( 319) 1177 174.8 1.9e-43 XP_016874467 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 1165 173.1 5.9e-43 XP_016874468 (OMIM: 132350) PREDICTED: syntaxin-2 ( 320) 1165 173.1 5.9e-43 XP_005253614 (OMIM: 132350) PREDICTED: syntaxin-2 ( 277) 1143 170.1 4.4e-42 NP_004168 (OMIM: 600876) syntaxin-3 isoform 1 [Hom ( 289) 1141 169.8 5.5e-42 XP_005274252 (OMIM: 600876) PREDICTED: syntaxin-3 ( 289) 1141 169.8 5.5e-42 XP_016874471 (OMIM: 132350) PREDICTED: syntaxin-2 ( 309) 1120 166.9 4.3e-41 XP_016873679 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 1117 166.5 5.3e-41 XP_016873680 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 1117 166.5 5.3e-41 XP_016873677 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 1117 166.5 5.3e-41 XP_016873678 (OMIM: 600876) PREDICTED: syntaxin-3 ( 281) 1117 166.5 5.3e-41 XP_016874470 (OMIM: 132350) PREDICTED: syntaxin-2 ( 317) 1116 166.4 6.4e-41 XP_016874472 (OMIM: 132350) PREDICTED: syntaxin-2 ( 260) 1109 165.3 1.1e-40 NP_001171511 (OMIM: 600876) syntaxin-3 isoform 2 [ ( 277) 1103 164.5 2e-40 XP_016873683 (OMIM: 600876) PREDICTED: syntaxin-3 ( 269) 1079 161.2 2e-39 XP_005274257 (OMIM: 600876) PREDICTED: syntaxin-3 ( 252) 934 141.2 2e-33 XP_016873684 (OMIM: 600876) PREDICTED: syntaxin-3 ( 244) 910 137.8 1.9e-32 XP_016874474 (OMIM: 132350) PREDICTED: syntaxin-2 ( 213) 838 127.9 1.7e-29 XP_016874473 (OMIM: 132350) PREDICTED: syntaxin-2 ( 214) 826 126.2 5.4e-29 XP_011543523 (OMIM: 600876) PREDICTED: syntaxin-3 ( 192) 822 125.6 7.3e-29 NP_004595 (OMIM: 186591) syntaxin-4 isoform 3 [Hom ( 297) 785 120.7 3.4e-27 XP_005255578 (OMIM: 186591) PREDICTED: syntaxin-4 ( 293) 715 111.0 2.8e-24 NP_001259025 (OMIM: 186591) syntaxin-4 isoform 2 [ ( 295) 715 111.0 2.8e-24 XP_016874477 (OMIM: 132350) PREDICTED: syntaxin-2 ( 167) 651 102.0 8.4e-22 XP_016874475 (OMIM: 132350) PREDICTED: syntaxin-2 ( 200) 633 99.5 5.3e-21 XP_016874476 (OMIM: 132350) PREDICTED: syntaxin-2 ( 199) 628 98.8 8.6e-21 NP_001259024 (OMIM: 186591) syntaxin-4 isoform 1 [ ( 219) 628 98.9 9.2e-21 XP_016873685 (OMIM: 600876) PREDICTED: syntaxin-3 ( 155) 615 97.0 2.5e-20 XP_011534519 (OMIM: 603552,605014) PREDICTED: synt ( 287) 500 81.3 2.3e-15 NP_003755 (OMIM: 603552,605014) syntaxin-11 [Homo ( 287) 500 81.3 2.3e-15 XP_011534516 (OMIM: 603552,605014) PREDICTED: synt ( 287) 500 81.3 2.3e-15 XP_011534520 (OMIM: 603552,605014) PREDICTED: synt ( 287) 500 81.3 2.3e-15 XP_016866889 (OMIM: 603552,605014) PREDICTED: synt ( 287) 500 81.3 2.3e-15 XP_011534515 (OMIM: 603552,605014) PREDICTED: synt ( 313) 500 81.4 2.5e-15 XP_011544227 (OMIM: 186591) PREDICTED: syntaxin-4 ( 154) 468 76.7 3.2e-14 XP_016874478 (OMIM: 132350) PREDICTED: syntaxin-2 ( 159) 345 59.7 4.2e-09 NP_001313508 (OMIM: 603217) syntaxin-7 isoform a [ ( 261) 299 53.5 4.9e-07 NP_001313507 (OMIM: 603217) syntaxin-7 isoform a [ ( 261) 299 53.5 4.9e-07 NP_003560 (OMIM: 603217) syntaxin-7 isoform a [Hom ( 261) 299 53.5 4.9e-07 NP_803173 (OMIM: 606892) syntaxin-12 [Homo sapiens ( 276) 291 52.5 1.1e-06 >>NP_004594 (OMIM: 186590) syntaxin-1A isoform 1 [Homo s (288 aa) initn: 1803 init1: 1803 opt: 1803 Z-score: 1368.6 bits: 261.2 E(85289): 1.7e-69 Smith-Waterman score: 1803; 100.0% identity (100.0% similar) in 288 aa overlap (1-288:1-288) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 190 200 210 220 230 240 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA :::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA 250 260 270 280 >>NP_443106 (OMIM: 601485,616172) syntaxin-1B [Homo sapi (288 aa) initn: 1461 init1: 1461 opt: 1543 Z-score: 1174.7 bits: 225.3 E(85289): 1.1e-58 Smith-Waterman score: 1543; 84.2% identity (96.8% similar) in 285 aa overlap (1-285:1-284) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA :::::::::.::::::...: : ::::.:::::::::::::: :.:..:.::.::..::: NP_443 MKDRTQELRSAKDSDDEEEV-VHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSA 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH :::.::::::::.:::.: .::::::::::::::.::::::::::::::::::::::::: NP_443 ILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :::::::::::.::::::: ::.::: ::::::::::::::.::::::::::. :::.. NP_443 STLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA : :::...::::.::::::.::::::.:::::::::.::::::::::::::::::::::. NP_443 IKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHS 180 190 200 210 220 230 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA :::::::::::::::::::::::::::::::::.::.:.::..:: NP_443 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL 240 250 260 270 280 >>XP_016878382 (OMIM: 601485,616172) PREDICTED: syntaxin (282 aa) initn: 1461 init1: 1461 opt: 1483 Z-score: 1130.1 bits: 217.0 E(85289): 3.3e-56 Smith-Waterman score: 1483; 84.0% identity (96.7% similar) in 275 aa overlap (11-285:5-278) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA ::::::...: : ::::.:::::::::::::: :.:..:.::.::..::: XP_016 MEPRAKDSDDEEEV-VHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSA 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH :::.::::::::.:::.: .::::::::::::::.::::::::::::::::::::::::: XP_016 ILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :::::::::::.::::::: ::.::: ::::::::::::::.::::::::::. :::.. XP_016 STLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA : :::...::::.::::::.::::::.:::::::::.::::::::::::::::::::::. XP_016 IKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHS 180 190 200 210 220 230 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA :::::::::::::::::::::::::::::::::.::.:.::..:: XP_016 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL 240 250 260 270 280 >>NP_001159375 (OMIM: 186590) syntaxin-1A isoform 2 [Hom (251 aa) initn: 1413 init1: 1413 opt: 1413 Z-score: 1078.5 bits: 207.3 E(85289): 2.5e-53 Smith-Waterman score: 1413; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA :::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQTMWRGPCLTPRRPS 190 200 210 220 230 240 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA NP_001 STRARRAGRKS 250 >>XP_016868056 (OMIM: 186590) PREDICTED: syntaxin-1A iso (329 aa) initn: 1413 init1: 1413 opt: 1413 Z-score: 1077.0 bits: 207.4 E(85289): 3e-53 Smith-Waterman score: 1413; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA :::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQVSAGPPCPPLQPTP 190 200 210 220 230 240 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA XP_016 APRAALTSPFLPDTLPCRGGTKFSGNQSPAVETAARALPTRRSLSSAWLCLSFKDPRPCM 250 260 270 280 290 300 >>XP_005274255 (OMIM: 600876) PREDICTED: syntaxin-3 isof (287 aa) initn: 521 init1: 521 opt: 1227 Z-score: 939.0 bits: 181.7 E(85289): 1.5e-45 Smith-Waterman score: 1227; 65.9% identity (88.3% similar) in 290 aa overlap (1-288:1-287) 10 20 30 40 50 pF1KB5 MKDRTQELRTAKDSDDDDD--VAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKH :::: ..:.. . ..::: : ...: :::::: ..:: : ::::.:.:::.:. . XP_005 MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 SAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKT : ::..: :. :::..::.: ..::: ::.::.::::.:. ::..: ::::::::::. XP_005 SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKS 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 QHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFA :::.:::::::::..:: .: :.::: ::::::::::::. ::.::::.::::::::::. XP_005 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVE :::: ::.:::::::::: ::..:..::.::.::::::::.:::::.::::.: :: :: XP_005 SGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 HAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA :.::.::.: ..:::::::::.::.:::::.:::.::.:..:::.:.::: XP_005 HTVDHVEKARDETKKAVKYQSQARKKKIMIMICCIILAIILASTIGSIFA 240 250 260 270 280 >>XP_016873682 (OMIM: 600876) PREDICTED: syntaxin-3 isof (279 aa) initn: 848 init1: 521 opt: 1203 Z-score: 921.3 bits: 178.3 E(85289): 1.4e-44 Smith-Waterman score: 1203; 66.2% identity (88.3% similar) in 281 aa overlap (8-288:2-279) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA .. ..:: : : ...: :::::: ..:: : ::::.:.:::.:. .: XP_016 MMKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSI 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH ::..: :. :::..::.: ..::: ::.::.::::.:. ::..: ::::::::::.:: XP_016 ILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKSQH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :.:::::::::..:: .: :.::: ::::::::::::. ::.::::.::::::::::.:: XP_016 SVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA :: ::.:::::::::: ::..:..::.::.::::::::.:::::.::::.: :: :: :. XP_016 II-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHT 180 190 200 210 220 230 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA ::.::.: ..:::::::::.::.:::::.:::.::.:..:::.:.::: XP_016 VDHVEKARDETKKAVKYQSQARKKKIMIMICCIILAIILASTIGSIFA 240 250 260 270 >>XP_016873681 (OMIM: 600876) PREDICTED: syntaxin-3 isof (279 aa) initn: 848 init1: 521 opt: 1203 Z-score: 921.3 bits: 178.3 E(85289): 1.4e-44 Smith-Waterman score: 1203; 66.2% identity (88.3% similar) in 281 aa overlap (8-288:2-279) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA .. ..:: : : ...: :::::: ..:: : ::::.:.:::.:. .: XP_016 MMKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSI 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH ::..: :. :::..::.: ..::: ::.::.::::.:. ::..: ::::::::::.:: XP_016 ILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDE--VRSSADLRIRKSQH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :.:::::::::..:: .: :.::: ::::::::::::. ::.::::.::::::::::.:: XP_016 SVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA :: ::.:::::::::: ::..:..::.::.::::::::.:::::.::::.: :: :: :. XP_016 II-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHT 180 190 200 210 220 230 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA ::.::.: ..:::::::::.::.:::::.:::.::.:..:::.:.::: XP_016 VDHVEKARDETKKAVKYQSQARKKKIMIMICCIILAIILASTIGSIFA 240 250 260 270 >>NP_001971 (OMIM: 132350) syntaxin-2 isoform 1 [Homo sa (287 aa) initn: 1348 init1: 1172 opt: 1200 Z-score: 918.9 bits: 177.9 E(85289): 1.9e-44 Smith-Waterman score: 1200; 65.9% identity (89.9% similar) in 287 aa overlap (1-283:1-286) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA :.:: .: :: ..:: :..:.:..:.:::.::.::::::. ::::.. :::::..:: NP_001 MRDRLPDL-TACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSI 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH ::..:::. : :::::.: ..:::::::.:.:::.::::..:.:. ::.:.:::::.::: NP_001 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :.:::::::.:.::: .:. .::: ::::::::::::::::..:::.:::::.:.::.: NP_001 SVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA :: ::.:..:::.:::.::..:.:::.::::::.:::::::.::.:::::. :: :: .: NP_001 IISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNA 180 190 200 210 220 230 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICC----VILGIVIASTVGGIFA .::::.: .::::.::::::::: ..:::: :::::..:.:. NP_001 TDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 240 250 260 270 280 >>NP_919337 (OMIM: 132350) syntaxin-2 isoform 2 [Homo sa (288 aa) initn: 1286 init1: 1170 opt: 1188 Z-score: 909.9 bits: 176.3 E(85289): 6.1e-44 Smith-Waterman score: 1188; 65.5% identity (89.1% similar) in 284 aa overlap (1-284:1-283) 10 20 30 40 50 60 pF1KB5 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA :.:: .: :: ..:: :..:.:..:.:::.::.::::::. ::::.. :::::..:: NP_919 MRDRLPDL-TACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSI 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH ::..:::. : :::::.: ..:::::::.:.:::.::::..:.:. ::.:.:::::.::: NP_919 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG :.:::::::.:.::: .:. .::: ::::::::::::::::..:::.:::::.:.::.: NP_919 SVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA :: ::.:..:::.:::.::..:.:::.::::::.:::::::.::.:::::. :: :: .: NP_919 IISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNA 180 190 200 210 220 230 250 260 270 280 pF1KB5 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA .::::.: .::::.:::::::::: .:: :.: .:: .: NP_919 TDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK 240 250 260 270 280 288 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:47:18 2016 done: Fri Nov 4 03:47:18 2016 Total Scan time: 5.210 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]