FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5476, 147 aa 1>>>pF1KB5476 147 - 147 aa - 147 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6099+/-0.000279; mu= 15.5812+/- 0.017 mean_var=60.2952+/-12.269, 0's: 0 Z-trim(119.9): 135 B-trim: 603 in 1/53 Lambda= 0.165171 statistics sampled from 34354 (34523) to 34354 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.784), E-opt: 0.2 (0.405), width: 16 Scan time: 5.120 The best scores are: opt bits E(85289) NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 1036 254.2 5.5e-68 NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 1036 254.2 5.5e-68 NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 1036 254.2 5.5e-68 NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 1036 254.2 5.5e-68 NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 1036 254.2 5.5e-68 NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 1036 254.2 5.5e-68 NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 1036 254.2 5.5e-68 NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 1024 251.4 4e-67 NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 1016 249.4 1.5e-66 NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 999 245.4 2.5e-65 XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 974 239.5 1.7e-63 NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 950 233.7 8.1e-62 NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 837 206.7 8.8e-54 XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 837 206.7 8.8e-54 NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 827 204.3 4.6e-53 XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 712 176.9 7.7e-45 NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 692 172.1 2.1e-43 XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 664 165.7 3.5e-41 NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 664 165.7 3.5e-41 NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 664 165.7 3.5e-41 NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 664 165.7 3.5e-41 NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 664 165.7 3.5e-41 NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 659 164.5 7.5e-41 XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 659 164.5 7.7e-41 NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 659 164.5 7.7e-41 NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 653 163.0 1.7e-40 NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 577 144.9 5.3e-35 XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 558 140.4 1.3e-33 XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 544 137.0 1.2e-32 NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 456 116.0 2.3e-26 NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 438 111.7 4.4e-25 NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 432 110.3 1.2e-24 NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 426 109.0 3.9e-24 NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 397 102.0 4.8e-22 NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 391 100.5 1.1e-21 NP_001243284 (OMIM: 603721) ubiquitin-conjugating ( 212) 383 98.7 5e-21 NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 379 97.7 8.1e-21 NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 376 96.9 1e-20 NP_055316 (OMIM: 610309) ubiquitin-conjugating enz ( 222) 364 94.2 1.2e-19 NP_001243285 (OMIM: 603721) ubiquitin-conjugating ( 122) 354 91.6 4e-19 NP_001104582 (OMIM: 602846) ubiquitin-conjugating ( 157) 355 92.0 4.1e-19 NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153) 351 91.0 7.8e-19 NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 347 90.1 1.5e-18 XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 347 90.1 1.5e-18 NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 347 90.1 1.5e-18 NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 347 90.1 1.5e-18 NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 347 90.1 1.5e-18 NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 345 89.6 2.4e-18 NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 326 85.0 4.5e-17 NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme ( 183) 318 83.2 2.1e-16 >>NP_871616 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 1036 init1: 1036 opt: 1036 Z-score: 1341.6 bits: 254.2 E(85289): 5.5e-68 Smith-Waterman score: 1036; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::::::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871620 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 1036 init1: 1036 opt: 1036 Z-score: 1341.6 bits: 254.2 E(85289): 5.5e-68 Smith-Waterman score: 1036; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::::::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 1036 init1: 1036 opt: 1036 Z-score: 1341.6 bits: 254.2 E(85289): 5.5e-68 Smith-Waterman score: 1036; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::::::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871619 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 1036 init1: 1036 opt: 1036 Z-score: 1341.6 bits: 254.2 E(85289): 5.5e-68 Smith-Waterman score: 1036; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::::::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_003331 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 1036 init1: 1036 opt: 1036 Z-score: 1341.6 bits: 254.2 E(85289): 5.5e-68 Smith-Waterman score: 1036; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::::::::::::: NP_003 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871615 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 1036 init1: 1036 opt: 1036 Z-score: 1341.6 bits: 254.2 E(85289): 5.5e-68 Smith-Waterman score: 1036; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::::::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 1036 init1: 1036 opt: 1036 Z-score: 1341.6 bits: 254.2 E(85289): 5.5e-68 Smith-Waterman score: 1036; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::::::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871621 (OMIM: 602963) ubiquitin-conjugating enzyme (148 aa) initn: 1024 init1: 1024 opt: 1024 Z-score: 1326.1 bits: 251.4 E(85289): 4e-67 Smith-Waterman score: 1024; 98.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::..::::.:::: NP_871 PEIARIYKTDRDKYNRLAREWTEKYAML 130 140 >>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa) initn: 1016 init1: 1016 opt: 1016 Z-score: 1315.8 bits: 249.4 E(85289): 1.5e-66 Smith-Waterman score: 1016; 97.3% identity (100.0% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB5 PEIARIYKTDRDKYNRISREWTQKYAM :::::::::::.:::::.::::::::: NP_003 PEIARIYKTDREKYNRIAREWTQKYAM 130 140 >>NP_871622 (OMIM: 602963) ubiquitin-conjugating enzyme (149 aa) initn: 999 init1: 999 opt: 999 Z-score: 1293.8 bits: 245.4 E(85289): 2.5e-65 Smith-Waterman score: 999; 97.9% identity (99.3% similar) in 144 aa overlap (4-147:6-149) 10 20 30 40 50 pF1KB5 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPT : ..::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 MLSNRKCLSKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDP 70 80 90 100 110 120 120 130 140 pF1KB5 LVPEIARIYKTDRDKYNRISREWTQKYAM ::::::::::::::::::::::::::::: NP_871 LVPEIARIYKTDRDKYNRISREWTQKYAM 130 140 147 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:00:58 2016 done: Sat Nov 5 13:00:58 2016 Total Scan time: 5.120 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]