FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5486, 193 aa 1>>>pF1KB5486 193 - 193 aa - 193 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8314+/-0.000982; mu= 10.6134+/- 0.059 mean_var=93.8390+/-18.756, 0's: 0 Z-trim(106.4): 99 B-trim: 5 in 1/52 Lambda= 0.132398 statistics sampled from 8871 (8975) to 8871 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.276), width: 16 Scan time: 1.930 The best scores are: opt bits E(32554) CCDS1671.1 HPCAL1 gene_id:3241|Hs108|chr2 ( 193) 1288 256.0 1e-68 CCDS370.1 HPCA gene_id:3208|Hs108|chr1 ( 193) 1212 241.5 2.4e-64 CCDS6292.1 NCALD gene_id:83988|Hs108|chr8 ( 193) 1201 239.4 1e-63 CCDS1689.1 VSNL1 gene_id:7447|Hs108|chr2 ( 191) 919 185.5 1.7e-47 CCDS441.1 HPCAL4 gene_id:51440|Hs108|chr1 ( 191) 899 181.7 2.4e-46 CCDS6932.1 NCS1 gene_id:23413|Hs108|chr9 ( 190) 803 163.4 7.9e-41 CCDS78448.1 NCS1 gene_id:23413|Hs108|chr9 ( 172) 715 146.5 8.4e-36 CCDS11151.1 RCVRN gene_id:5957|Hs108|chr17 ( 200) 697 143.1 1e-34 CCDS64313.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 188) 565 117.9 3.8e-27 CCDS4374.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 216) 565 117.9 4.2e-27 CCDS34285.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 225) 565 118.0 4.4e-27 CCDS34286.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 227) 565 118.0 4.4e-27 CCDS7524.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 220) 546 114.3 5.3e-26 CCDS7525.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 225) 546 114.3 5.4e-26 CCDS41562.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 252) 546 114.4 5.9e-26 CCDS7522.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 270) 546 114.4 6.2e-26 CCDS7521.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 285) 546 114.4 6.5e-26 CCDS33245.1 KCNIP3 gene_id:30818|Hs108|chr2 ( 230) 538 112.8 1.6e-25 CCDS2013.1 KCNIP3 gene_id:30818|Hs108|chr2 ( 256) 538 112.8 1.7e-25 CCDS47035.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 188) 529 111.0 4.5e-25 CCDS43215.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 216) 529 111.1 5e-25 CCDS43217.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 225) 529 111.1 5.1e-25 CCDS3428.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 229) 529 111.1 5.2e-25 CCDS43216.1 KCNIP4 gene_id:80333|Hs108|chr4 ( 250) 529 111.1 5.6e-25 CCDS7523.1 KCNIP2 gene_id:30819|Hs108|chr10 ( 227) 528 110.9 5.9e-25 CCDS4865.1 GUCA1B gene_id:2979|Hs108|chr6 ( 200) 522 109.7 1.2e-24 CCDS4864.1 GUCA1A gene_id:2978|Hs108|chr6 ( 201) 490 103.6 8.2e-23 CCDS2954.1 GUCA1C gene_id:9626|Hs108|chr3 ( 209) 397 85.8 1.9e-17 CCDS64312.1 KCNIP1 gene_id:30820|Hs108|chr5 ( 241) 383 83.2 1.3e-16 >>CCDS1671.1 HPCAL1 gene_id:3241|Hs108|chr2 (193 aa) initn: 1288 init1: 1288 opt: 1288 Z-score: 1347.0 bits: 256.0 E(32554): 1e-68 Smith-Waterman score: 1288; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 130 140 150 160 170 180 190 pF1KB5 RLLQCDPSSASQF ::::::::::::: CCDS16 RLLQCDPSSASQF 190 >>CCDS370.1 HPCA gene_id:3208|Hs108|chr1 (193 aa) initn: 1212 init1: 1212 opt: 1212 Z-score: 1268.6 bits: 241.5 E(32554): 2.4e-64 Smith-Waterman score: 1212; 94.3% identity (97.9% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD :::::::::::.::::::::::.. :::::::::::::::: :.:::::::::::::::: CCDS37 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE :::::::::::::::.:::::::::::::::::::.::::: :::::::::::::::: : CCDS37 ASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV :::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::: CCDS37 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 130 140 150 160 170 180 190 pF1KB5 RLLQCDPSSASQF ::::::::::::: CCDS37 RLLQCDPSSASQF 190 >>CCDS6292.1 NCALD gene_id:83988|Hs108|chr8 (193 aa) initn: 1201 init1: 1201 opt: 1201 Z-score: 1257.2 bits: 239.4 E(32554): 1e-63 Smith-Waterman score: 1201; 90.7% identity (99.0% similar) in 193 aa overlap (1-193:1-193) 10 20 30 40 50 60 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD ::::::::::::.::: :.:.::.::.::::::::.:::.:::...::::::.::::::: CCDS62 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::..: CCDS62 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV :::::::::::::::::::::::::::::.::::::::: :::::::::::::::::::: CCDS62 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIV 130 140 150 160 170 180 190 pF1KB5 RLLQCDPSSASQF ::::::::::.:: CCDS62 RLLQCDPSSAGQF 190 >>CCDS1689.1 VSNL1 gene_id:7447|Hs108|chr2 (191 aa) initn: 725 init1: 725 opt: 919 Z-score: 966.2 bits: 185.5 E(32554): 1.7e-47 Smith-Waterman score: 919; 69.7% identity (91.5% similar) in 188 aa overlap (1-186:1-188) 10 20 30 40 50 60 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD :::::::: :::..:: ..:::..:::..::::::::::.:.:...::...:..:::::: CCDS16 MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE :::::.:.::::: :::::::::::: :::.::::..::::.:::.::::::.: :.: : CCDS16 ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPS ::::..::::::..: ::: :: :::.:.:::: .:: :.: ...:.:: ..:::::: CCDS16 MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS 130 140 150 160 170 180 180 190 pF1KB5 IVRLLQCDPSSASQF :: ::::: CCDS16 IVLLLQCDIQK 190 >>CCDS441.1 HPCAL4 gene_id:51440|Hs108|chr1 (191 aa) initn: 708 init1: 708 opt: 899 Z-score: 945.5 bits: 181.7 E(32554): 2.4e-46 Smith-Waterman score: 899; 68.6% identity (89.9% similar) in 188 aa overlap (1-186:1-188) 10 20 30 40 50 60 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD ::: :::: ::::.:: .::::...::..::::::::::.: :...::...: .:::::: CCDS44 MGKTNSKLAPEVLEDLVQNTEFSEQELKQWYKGFLKDCPSGILNLEEFQQLYIKFFPYGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE :::::.:.::::: :::::::::::: ::::::::..::::.::: ::::::.: :.: : CCDS44 ASKFAQHAFRTFDKNGDGTIDFREFICALSVTSRGSFEQKLNWAFEMYDLDGDGRITRLE 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 MLEIVQAIYKMVSSV--MKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPS ::::..::::::..: :.: .: ::..:.::::..:: ..: ...:::: ..:::::: CCDS44 MLEIIEAIYKMVGTVIMMRMNQDGLTPQQRVDKIFKKMDQDKDDQITLEEFKEAAKSDPS 130 140 150 160 170 180 180 190 pF1KB5 IVRLLQCDPSSASQF :: ::::: CCDS44 IVLLLQCDMQK 190 >>CCDS6932.1 NCS1 gene_id:23413|Hs108|chr9 (190 aa) initn: 849 init1: 803 opt: 803 Z-score: 846.4 bits: 163.4 E(32554): 7.9e-41 Smith-Waterman score: 803; 61.2% identity (88.5% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD :::.::::.:::...: ..: ::..:.:.:::::.::::.:.: . :.::: .:::.:: CCDS69 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE .::: :: .:: : :: :.: ::: :::::::: :..::.:::..::::..:::.:.: CCDS69 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 MLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV ::.::.:::.::......::.:.:::::.:.:: .:: : ::::.:.:: .:.:.::::: CCDS69 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 130 140 150 160 170 180 190 pF1KB5 RLLQCDPSSASQF . : CCDS69 QALSLYDGLV 190 >>CCDS78448.1 NCS1 gene_id:23413|Hs108|chr9 (172 aa) initn: 738 init1: 692 opt: 715 Z-score: 756.2 bits: 146.5 E(32554): 8.4e-36 Smith-Waterman score: 715; 61.5% identity (88.2% similar) in 161 aa overlap (23-183:5-165) 10 20 30 40 50 60 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD :..:.:.:::::.::::.:.: . :.::: .:::.:: CCDS78 MATITEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 10 20 30 40 70 80 90 100 110 120 pF1KB5 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE .::: :: .:: : :: :.: ::: :::::::: :..::.:::..::::..:::.:.: CCDS78 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 MLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV ::.::.:::.::......::.:.:::::.:.:: .:: : ::::.:.:: .:.:.::::: CCDS78 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 110 120 130 140 150 160 190 pF1KB5 RLLQCDPSSASQF . : CCDS78 QALSLYDGLV 170 >>CCDS11151.1 RCVRN gene_id:5957|Hs108|chr17 (200 aa) initn: 650 init1: 510 opt: 697 Z-score: 736.7 bits: 143.1 E(32554): 1e-34 Smith-Waterman score: 697; 50.8% identity (84.6% similar) in 195 aa overlap (1-192:1-195) 10 20 30 40 50 pF1KB5 MGKQNS-KLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYG ::...: : :.:..:. ::.:...:: ::..::::::::..: ..:..:::.::: CCDS11 MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 DASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRS : . .:.::::.::.: :::.::.:..::: .:. :: .:::.::::.::.:::: ::.. CCDS11 DPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 EMLEIVQAIYKMVS--SVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDP :.::::.::.::.. .: .:.::.:::::..::.. . :.: ::. .:::.:. .. CCDS11 EVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANK 130 140 150 160 170 180 180 190 pF1KB5 SIVRLLQCDPSSASQF :.::.: .:..... CCDS11 EILRLIQFEPQKVKEKMKNA 190 200 >>CCDS64313.1 KCNIP1 gene_id:30820|Hs108|chr5 (188 aa) initn: 565 init1: 565 opt: 565 Z-score: 600.8 bits: 117.9 E(32554): 3.8e-27 Smith-Waterman score: 565; 44.3% identity (80.1% similar) in 176 aa overlap (9-184:7-182) 10 20 30 40 50 60 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGD ::: :..:. .:.:: .::: :.:: ..::.: .. : ::.:::.:::.:: CCDS64 MTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEDTFKQIYAQFFPHGD 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 ASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSE :: .:...: .:::. :.. :..:. :::. :: ...::.:.:..::.. .:::.. : CCDS64 ASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 MLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV :..::.::: :... :.::....: .:..:: :.:: ..:.::... . : .:. CCDS64 MMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIM 120 130 140 150 160 170 190 pF1KB5 RLLQCDPSSASQF : :: CCDS64 RSLQLFQNVM 180 >>CCDS4374.1 KCNIP1 gene_id:30820|Hs108|chr5 (216 aa) initn: 565 init1: 565 opt: 565 Z-score: 600.0 bits: 117.9 E(32554): 4.2e-27 Smith-Waterman score: 565; 44.3% identity (80.1% similar) in 176 aa overlap (9-184:35-210) 10 20 30 pF1KB5 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDC ::: :..:. .:.:: .::: :.:: ..: CCDS43 MGTFSSLQTKQRRPSKDKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNEC 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 PTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLE :.: .. : ::.:::.:::.:::: .:...: .:::. :.. :..:. :::. :: .. CCDS43 PSGVVNEDTFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 QKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDT .::.:.:..::.. .:::.. ::..::.::: :... :.::....: .:..:: CCDS43 EKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDK 130 140 150 160 170 180 160 170 180 190 pF1KB5 NNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF :.:: ..:.::... . : .:.: :: CCDS43 NKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM 190 200 210 193 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:49:50 2016 done: Fri Nov 4 03:49:51 2016 Total Scan time: 1.930 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]