FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5493, 908 aa 1>>>pF1KB5493 908 - 908 aa - 908 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2651+/-0.00105; mu= 17.8176+/- 0.064 mean_var=99.6803+/-19.666, 0's: 0 Z-trim(106.4): 14 B-trim: 219 in 1/49 Lambda= 0.128460 statistics sampled from 8958 (8965) to 8958 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.275), width: 16 Scan time: 4.600 The best scores are: opt bits E(32554) CCDS3258.1 PSMD2 gene_id:5708|Hs108|chr3 ( 908) 5896 1103.8 0 CCDS63853.1 PSMD2 gene_id:5708|Hs108|chr3 ( 778) 5047 946.4 0 CCDS63854.1 PSMD2 gene_id:5708|Hs108|chr3 ( 749) 4825 905.3 0 >>CCDS3258.1 PSMD2 gene_id:5708|Hs108|chr3 (908 aa) initn: 5896 init1: 5896 opt: 5896 Z-score: 5904.9 bits: 1103.8 E(32554): 0 Smith-Waterman score: 5896; 99.9% identity (99.9% similar) in 908 aa overlap (1-908:1-908) 10 20 30 40 50 60 pF1KB5 MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDELEMLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDELEMLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 ERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 FAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAKEWQELDDAEKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 FAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAKEWQELDDAEKVQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 REPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 REPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PEPENSALLCCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGR ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 PEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 HGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 DVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 SIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 TIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 AMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 VSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 YHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 YHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 PVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 PVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVIL 850 860 870 880 890 900 pF1KB5 RKNPNYDL :::::::: CCDS32 RKNPNYDL >>CCDS63853.1 PSMD2 gene_id:5708|Hs108|chr3 (778 aa) initn: 5047 init1: 5047 opt: 5047 Z-score: 5055.5 bits: 946.4 E(32554): 0 Smith-Waterman score: 5047; 99.9% identity (99.9% similar) in 778 aa overlap (131-908:1-778) 110 120 130 140 150 160 pF1KB5 PHYGKLKEIYENMAPGENKRFAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVR :::::::::::::::::::::::::::::: CCDS63 MTMSGERECLKYRLVGSQEELASWGHEYVR 10 20 30 170 180 190 200 210 220 pF1KB5 HLAGEVAKEWQELDDAEKVQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 HLAGEVAKEWQELDDAEKVQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKD 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB5 IDENAYAKVCLYLTSCVNYVPEPENSALLCCALGVFRKFSRFPEALRLALMLNDMELVED ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: CCDS63 IDENAYAKVCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVED 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB5 IFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 IFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIM 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB5 EPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLY 220 230 240 250 260 270 410 420 430 440 450 460 pF1KB5 KNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 KNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECD 280 290 300 310 320 330 470 480 490 500 510 520 pF1KB5 PALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTAL 340 350 360 370 380 390 530 540 550 560 570 580 pF1KB5 ACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAAL 400 410 420 430 440 450 590 600 610 620 630 640 pF1KB5 EVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKK 460 470 480 490 500 510 650 660 670 680 690 700 pF1KB5 EAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVS 520 530 540 550 560 570 710 720 730 740 750 760 pF1KB5 NPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLF 580 590 600 610 620 630 770 780 790 800 810 820 pF1KB5 MVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYG 640 650 660 670 680 690 830 840 850 860 870 880 pF1KB5 LVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERA 700 710 720 730 740 750 890 900 pF1KB5 ELATEEFLPVTPILEGFVILRKNPNYDL :::::::::::::::::::::::::::: CCDS63 ELATEEFLPVTPILEGFVILRKNPNYDL 760 770 >>CCDS63854.1 PSMD2 gene_id:5708|Hs108|chr3 (749 aa) initn: 4825 init1: 4825 opt: 4825 Z-score: 4833.4 bits: 905.3 E(32554): 0 Smith-Waterman score: 4825; 99.6% identity (99.9% similar) in 747 aa overlap (162-908:3-749) 140 150 160 170 180 190 pF1KB5 TMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAKEWQELDDAEKVQREPLLTLVKEI ..:::::::::::::::::::::::::::: CCDS63 MSMSGEVAKEWQELDDAEKVQREPLLTLVKEI 10 20 30 200 210 220 230 240 250 pF1KB5 VPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : CCDS63 VPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLRC 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB5 ALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDV 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB5 EEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMN 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB5 LASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDK 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB5 YLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 YLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAG 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB5 SNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELK 340 350 360 370 380 390 560 570 580 590 600 610 pF1KB5 DTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQ 400 410 420 430 440 450 620 630 640 650 660 670 pF1KB5 LLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALIAMGEEIGAEMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALIAMGEEIGAEMA 460 470 480 490 500 510 680 690 700 710 720 730 pF1KB5 LRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGM 520 530 540 550 560 570 740 750 760 770 780 790 pF1KB5 VGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQV 580 590 600 610 620 630 800 810 820 830 840 850 pF1KB5 AVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 AVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVD 640 650 660 670 680 690 860 870 880 890 900 pF1KB5 VVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYDL 700 710 720 730 740 908 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:28:03 2016 done: Thu Nov 3 17:28:04 2016 Total Scan time: 4.600 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]