FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5514, 447 aa 1>>>pF1KB5514 447 - 447 aa - 447 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8375+/-0.000438; mu= 14.7679+/- 0.027 mean_var=75.9783+/-14.799, 0's: 0 Z-trim(110.0): 45 B-trim: 0 in 0/52 Lambda= 0.147140 statistics sampled from 18285 (18329) to 18285 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.215), width: 16 Scan time: 8.350 The best scores are: opt bits E(85289) NP_002708 (OMIM: 604941) serine/threonine-protein ( 447) 2998 646.4 4.5e-185 NP_001171062 (OMIM: 604941) serine/threonine-prote ( 457) 2986 643.8 2.7e-184 XP_005273616 (OMIM: 604941) PREDICTED: serine/thre ( 446) 2981 642.8 5.5e-184 XP_011542867 (OMIM: 604941) PREDICTED: serine/thre ( 456) 2969 640.2 3.3e-183 NP_060931 (OMIM: 613992) serine/threonine-protein ( 453) 2739 591.4 1.6e-168 NP_001258828 (OMIM: 604325,604326) serine/threonin ( 449) 2679 578.7 1.1e-164 NP_858062 (OMIM: 604325,604326) serine/threonine-p ( 446) 2606 563.2 5.1e-160 NP_001258829 (OMIM: 604325,604326) serine/threonin ( 501) 2606 563.2 5.6e-160 NP_858060 (OMIM: 604325,604326) serine/threonine-p ( 509) 2606 563.2 5.7e-160 NP_858061 (OMIM: 604325,604326) serine/threonine-p ( 549) 2606 563.2 6e-160 NP_858064 (OMIM: 604325,604326) serine/threonine-p ( 432) 2601 562.1 1e-159 NP_001258877 (OMIM: 604325,604326) serine/threonin ( 432) 2601 562.1 1e-159 NP_858063 (OMIM: 604325,604326) serine/threonine-p ( 423) 2596 561.0 2.1e-159 NP_065149 (OMIM: 605997) protein phosphatase 2, re ( 447) 2495 539.6 6.3e-153 XP_011511797 (OMIM: 605997) PREDICTED: protein pho ( 433) 2491 538.7 1.1e-152 NP_001193925 (OMIM: 605997) protein phosphatase 2, ( 430) 2484 537.3 3.1e-152 NP_001193924 (OMIM: 605997) protein phosphatase 2, ( 440) 2484 537.3 3.1e-152 NP_001193923 (OMIM: 605997) protein phosphatase 2, ( 440) 2484 537.3 3.1e-152 NP_870991 (OMIM: 605997) protein phosphatase 2, re ( 447) 2484 537.3 3.2e-152 XP_016871895 (OMIM: 613992) PREDICTED: serine/thre ( 454) 2395 518.4 1.6e-146 XP_006717977 (OMIM: 613992) PREDICTED: serine/thre ( 369) 2205 478.0 1.8e-134 XP_005273617 (OMIM: 604941) PREDICTED: serine/thre ( 288) 1934 420.4 3e-117 XP_011542869 (OMIM: 604941) PREDICTED: serine/thre ( 288) 1934 420.4 3e-117 XP_011542868 (OMIM: 604941) PREDICTED: serine/thre ( 288) 1934 420.4 3e-117 XP_011542870 (OMIM: 604941) PREDICTED: serine/thre ( 288) 1934 420.4 3e-117 XP_011542871 (OMIM: 604941) PREDICTED: serine/thre ( 288) 1934 420.4 3e-117 XP_016871896 (OMIM: 613992) PREDICTED: serine/thre ( 370) 1861 405.0 1.7e-112 NP_001278239 (OMIM: 613992) serine/threonine-prote ( 288) 1812 394.5 1.9e-109 XP_011511798 (OMIM: 605997) PREDICTED: protein pho ( 292) 1761 383.7 3.5e-106 XP_006717978 (OMIM: 613992) PREDICTED: serine/thre ( 226) 1413 309.8 4.8e-84 XP_016871897 (OMIM: 613992) PREDICTED: serine/thre ( 226) 1413 309.8 4.8e-84 XP_005248036 (OMIM: 605997) PREDICTED: protein pho ( 230) 1386 304.0 2.6e-82 >>NP_002708 (OMIM: 604941) serine/threonine-protein phos (447 aa) initn: 2998 init1: 2998 opt: 2998 Z-score: 3443.6 bits: 646.4 E(85289): 4.5e-185 Smith-Waterman score: 2998; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447) 10 20 30 40 50 60 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 TFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 MTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 SYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKIL 370 380 390 400 410 420 430 440 pF1KB5 HTAWHPKENIIAVATTNNLYIFQDKVN ::::::::::::::::::::::::::: NP_002 HTAWHPKENIIAVATTNNLYIFQDKVN 430 440 >>NP_001171062 (OMIM: 604941) serine/threonine-protein p (457 aa) initn: 2986 init1: 2986 opt: 2986 Z-score: 3429.7 bits: 643.8 E(85289): 2.7e-184 Smith-Waterman score: 2986; 100.0% identity (100.0% similar) in 445 aa overlap (3-447:13-457) 10 20 30 40 50 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGG :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFPKFSLRSMFHGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 RVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 LLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 IFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVIT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 AAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISD 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 VKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCW 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 NGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISV 370 380 390 400 410 420 420 430 440 pF1KB5 DSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN ::::::::::::::::::::::::::::::::::::: NP_001 DSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN 430 440 450 >>XP_005273616 (OMIM: 604941) PREDICTED: serine/threonin (446 aa) initn: 2810 init1: 2810 opt: 2981 Z-score: 3424.1 bits: 642.8 E(85289): 5.5e-184 Smith-Waterman score: 2981; 99.8% identity (99.8% similar) in 447 aa overlap (1-447:1-446) 10 20 30 40 50 60 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQE ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_005 MAGAGGGNDIQWCFSQVKGAVDDDVAE-DIISTVEFNHSGELLATGDKGGRVVIFQQEQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 NKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 NSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 TFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYM 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 MTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTG 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 SYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKIL 360 370 380 390 400 410 430 440 pF1KB5 HTAWHPKENIIAVATTNNLYIFQDKVN ::::::::::::::::::::::::::: XP_005 HTAWHPKENIIAVATTNNLYIFQDKVN 420 430 440 >>XP_011542867 (OMIM: 604941) PREDICTED: serine/threonin (456 aa) initn: 2810 init1: 2810 opt: 2969 Z-score: 3410.2 bits: 640.2 E(85289): 3.3e-183 Smith-Waterman score: 2969; 99.8% identity (99.8% similar) in 445 aa overlap (3-447:13-456) 10 20 30 40 50 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGG ::::::::::::::::::::::::: :::::::::::::::::::::: XP_011 MFPKFSLRSMFHGAGGGNDIQWCFSQVKGAVDDDVAE-DIISTVEFNHSGELLATGDKGG 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 RVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 IFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVIT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISD 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 VKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCW 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 NGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISV 360 370 380 390 400 410 420 430 440 pF1KB5 DSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN ::::::::::::::::::::::::::::::::::::: XP_011 DSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN 420 430 440 450 >>NP_060931 (OMIM: 613992) serine/threonine-protein phos (453 aa) initn: 2814 init1: 2728 opt: 2739 Z-score: 3146.4 bits: 591.4 E(85289): 1.6e-168 Smith-Waterman score: 2739; 87.9% identity (96.9% similar) in 453 aa overlap (1-447:1-453) 10 20 30 40 50 pF1KB5 MAGAGGG------NDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVI ::::::: ::.::::::::::.:.::::::::::::::.::.::::::::::::: NP_060 MAGAGGGGCPAGGNDFQWCFSQVKGAIDEDVAEADIISTVEFNYSGDLLATGDKGGRVVI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 FQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLST ::.::::: . :::::::::::::::::::::::::::::::::::::::.:::.::::: NP_060 FQREQENKSRPHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLST 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 NDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFAN :::::::::::::::: ::::::.:::: ::: .:.::::...:::::::::::::::: NP_060 NDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFAN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 AHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEF ::::::::::.:::.::::::::::::::::::::::::::::::::::::::::::::: NP_060 AHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 HPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFS ::..::.::::::::::::::::.:::::::::.::::::::.::::::::::::::::: NP_060 HPHQCNVFVYSSSKGTIRLCDMRSSALCDRHSKFFEEPEDPSSRSFFSEIISSISDVKFS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 HSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSD :::::::::::::::.::::::.:::::.::::::::::::::::::::::::::::::: NP_060 HSGRYMMTRDYLSVKVWDLNMESRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 SVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLD :..::::::::::::::.:.::.:::::::..:::. :::::::..:::.:::::::::: NP_060 SAIMTGSYNNFFRMFDRDTRRDVTLEASRESSKPRASLKPRKVCTGGKRRKDEISVDSLD 370 380 390 400 410 420 420 430 440 pF1KB5 FNKKILHTAWHPKENIIAVATTNNLYIFQDKVN :::::::::::: .:.::::.::::::::::.: NP_060 FNKKILHTAWHPVDNVIAVAATNNLYIFQDKIN 430 440 450 >>NP_001258828 (OMIM: 604325,604326) serine/threonine-pr (449 aa) initn: 2679 init1: 2679 opt: 2679 Z-score: 3077.6 bits: 578.7 E(85289): 1.1e-164 Smith-Waterman score: 2679; 87.7% identity (97.5% similar) in 439 aa overlap (9-447:11-449) 10 20 30 40 50 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQE : ::::::::... ..::::::::::::.:::::::::::::::::.: NP_001 MIPGIGTLTQDTLWCFSQVKGTIEIGTTEADIISTVEFNHTGELLATGDKGGRVVIFQRE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 QENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKT ::.: : : :::::::::::::::::::::::::::::::::::::.::: ::::::::: NP_001 QESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 IKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTY .::::.:::::::::::::.:.:: :::.:.:::::::.:::::::::.:::.::::::: NP_001 VKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 HINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNS ::::::.:::::::.::::::::::..:::..::::::::::::::::::::::::::. NP_001 HINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHH 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 CNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGR :::::::::::::::::::::::::::.:.:::::::::::::::::::::::::::::: NP_001 CNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 YMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVM :.::::::.::.:::::::::.::::::.::::::::::::::::::::: :::::::.: NP_001 YIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIM 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 TGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKK ::::::::::::::::::.::::::::.:::..:::::::..:::.:::::::::::.:: NP_001 TGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFSKK 370 380 390 400 410 420 420 430 440 pF1KB5 ILHTAWHPKENIIAVATTNNLYIFQDKVN ::::::::.:::::::.:::::::::::: NP_001 ILHTAWHPSENIIAVAATNNLYIFQDKVN 430 440 >>NP_858062 (OMIM: 604325,604326) serine/threonine-prote (446 aa) initn: 2606 init1: 2606 opt: 2606 Z-score: 2993.9 bits: 563.2 E(85289): 5.1e-160 Smith-Waterman score: 2606; 89.3% identity (98.3% similar) in 421 aa overlap (27-447:26-446) 10 20 30 40 50 60 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQE ::::::::::::.:::::::::::::::::.::: NP_858 MKCFSRYLPYIFRPPNTILSSSCHTEADIISTVEFNHTGELLATGDKGGRVVIFQREQE 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 NKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIK .: : : :::::::::::::::::::::::::::::::::::::.::: :::::::::.: NP_858 SKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 LWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHI :::.:::::::::::::.:.:: :::.:.:::::::.:::::::::.:::.::::::::: NP_858 LWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 NSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCN ::::.:::::::.::::::::::..:::..::::::::::::::::::::::::::. :: NP_858 NSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 TFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYM :::::::::::::::::::::::::.:.:::::::::::::::::::::::::::::::. NP_858 TFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYI 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 MTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTG ::::::.::.:::::::::.::::::.::::::::::::::::::::: :::::::.::: NP_858 MTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTG 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 SYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKIL ::::::::::::::::.::::::::.:::..:::::::..:::.:::::::::::.:::: NP_858 SYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFSKKIL 360 370 380 390 400 410 430 440 pF1KB5 HTAWHPKENIIAVATTNNLYIFQDKVN ::::::.:::::::.:::::::::::: NP_858 HTAWHPSENIIAVAATNNLYIFQDKVN 420 430 440 >>NP_001258829 (OMIM: 604325,604326) serine/threonine-pr (501 aa) initn: 2606 init1: 2606 opt: 2606 Z-score: 2993.1 bits: 563.2 E(85289): 5.6e-160 Smith-Waterman score: 2606; 89.3% identity (98.3% similar) in 421 aa overlap (27-447:81-501) 10 20 30 40 50 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQ ::::::::::::.::::::::::::::::: NP_001 PTQVSLLSMEEDIDTRKINNSFLRDHSYATEADIISTVEFNHTGELLATGDKGGRVVIFQ 60 70 80 90 100 110 60 70 80 90 100 110 pF1KB5 QEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTND .:::.: : : :::::::::::::::::::::::::::::::::::::.::: ::::::: NP_001 REQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTND 120 130 140 150 160 170 120 130 140 150 160 170 pF1KB5 KTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAH ::.::::.:::::::::::::.:.:: :::.:.:::::::.:::::::::.:::.::::: NP_001 KTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAH 180 190 200 210 220 230 180 190 200 210 220 230 pF1KB5 TYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHP ::::::::.:::::::.::::::::::..:::..:::::::::::::::::::::::::: NP_001 TYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHP 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB5 NSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHS . :::::::::::::::::::::::::::.:.:::::::::::::::::::::::::::: NP_001 HHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHS 300 310 320 330 340 350 300 310 320 330 340 350 pF1KB5 GRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSV :::.::::::.::.:::::::::.::::::.::::::::::::::::::::: ::::::: NP_001 GRYIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSV 360 370 380 390 400 410 360 370 380 390 400 410 pF1KB5 VMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFN .:::::::::::::::::::.::::::::.:::..:::::::..:::.:::::::::::. NP_001 IMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFS 420 430 440 450 460 470 420 430 440 pF1KB5 KKILHTAWHPKENIIAVATTNNLYIFQDKVN ::::::::::.:::::::.:::::::::::: NP_001 KKILHTAWHPSENIIAVAATNNLYIFQDKVN 480 490 500 >>NP_858060 (OMIM: 604325,604326) serine/threonine-prote (509 aa) initn: 2606 init1: 2606 opt: 2606 Z-score: 2993.0 bits: 563.2 E(85289): 5.7e-160 Smith-Waterman score: 2606; 89.3% identity (98.3% similar) in 421 aa overlap (27-447:89-509) 10 20 30 40 50 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQ ::::::::::::.::::::::::::::::: NP_858 PTQVSLLSMEEDIDTRKINNSFLRDHSYATEADIISTVEFNHTGELLATGDKGGRVVIFQ 60 70 80 90 100 110 60 70 80 90 100 110 pF1KB5 QEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTND .:::.: : : :::::::::::::::::::::::::::::::::::::.::: ::::::: NP_858 REQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTND 120 130 140 150 160 170 120 130 140 150 160 170 pF1KB5 KTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAH ::.::::.:::::::::::::.:.:: :::.:.:::::::.:::::::::.:::.::::: NP_858 KTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAH 180 190 200 210 220 230 180 190 200 210 220 230 pF1KB5 TYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHP ::::::::.:::::::.::::::::::..:::..:::::::::::::::::::::::::: NP_858 TYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHP 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB5 NSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHS . :::::::::::::::::::::::::::.:.:::::::::::::::::::::::::::: NP_858 HHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHS 300 310 320 330 340 350 300 310 320 330 340 350 pF1KB5 GRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSV :::.::::::.::.:::::::::.::::::.::::::::::::::::::::: ::::::: NP_858 GRYIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSV 360 370 380 390 400 410 360 370 380 390 400 410 pF1KB5 VMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFN .:::::::::::::::::::.::::::::.:::..:::::::..:::.:::::::::::. NP_858 IMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFS 420 430 440 450 460 470 420 430 440 pF1KB5 KKILHTAWHPKENIIAVATTNNLYIFQDKVN ::::::::::.:::::::.:::::::::::: NP_858 KKILHTAWHPSENIIAVAATNNLYIFQDKVN 480 490 500 >>NP_858061 (OMIM: 604325,604326) serine/threonine-prote (549 aa) initn: 2606 init1: 2606 opt: 2606 Z-score: 2992.5 bits: 563.2 E(85289): 6e-160 Smith-Waterman score: 2606; 89.3% identity (98.3% similar) in 421 aa overlap (27-447:129-549) 10 20 30 40 50 pF1KB5 MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQ ::::::::::::.::::::::::::::::: NP_858 PTQVSLLSMEEDIDTRKINNSFLRDHSYATEADIISTVEFNHTGELLATGDKGGRVVIFQ 100 110 120 130 140 150 60 70 80 90 100 110 pF1KB5 QEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTND .:::.: : : :::::::::::::::::::::::::::::::::::::.::: ::::::: NP_858 REQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTND 160 170 180 190 200 210 120 130 140 150 160 170 pF1KB5 KTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAH ::.::::.:::::::::::::.:.:: :::.:.:::::::.:::::::::.:::.::::: NP_858 KTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAH 220 230 240 250 260 270 180 190 200 210 220 230 pF1KB5 TYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHP ::::::::.:::::::.::::::::::..:::..:::::::::::::::::::::::::: NP_858 TYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHP 280 290 300 310 320 330 240 250 260 270 280 290 pF1KB5 NSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHS . :::::::::::::::::::::::::::.:.:::::::::::::::::::::::::::: NP_858 HHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHS 340 350 360 370 380 390 300 310 320 330 340 350 pF1KB5 GRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSV :::.::::::.::.:::::::::.::::::.::::::::::::::::::::: ::::::: NP_858 GRYIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSV 400 410 420 430 440 450 360 370 380 390 400 410 pF1KB5 VMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFN .:::::::::::::::::::.::::::::.:::..:::::::..:::.:::::::::::. NP_858 IMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFS 460 470 480 490 500 510 420 430 440 pF1KB5 KKILHTAWHPKENIIAVATTNNLYIFQDKVN ::::::::::.:::::::.:::::::::::: NP_858 KKILHTAWHPSENIIAVAATNNLYIFQDKVN 520 530 540 447 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:36:50 2016 done: Thu Nov 3 22:36:51 2016 Total Scan time: 8.350 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]