FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5535, 463 aa 1>>>pF1KB5535 463 - 463 aa - 463 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2032+/-0.000885; mu= 18.0071+/- 0.053 mean_var=63.1050+/-12.573, 0's: 0 Z-trim(105.2): 23 B-trim: 55 in 2/47 Lambda= 0.161452 statistics sampled from 8273 (8293) to 8273 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.255), width: 16 Scan time: 2.930 The best scores are: opt bits E(32554) CCDS8282.1 CTSC gene_id:1075|Hs108|chr11 ( 463) 3206 755.6 2.4e-218 CCDS31654.1 CTSC gene_id:1075|Hs108|chr11 ( 137) 719 176.1 2e-44 CCDS44693.1 CTSC gene_id:1075|Hs108|chr11 ( 141) 719 176.1 2.1e-44 CCDS6723.1 CTSV gene_id:1515|Hs108|chr9 ( 334) 452 114.1 2.3e-25 CCDS13474.1 CTSZ gene_id:1522|Hs108|chr20 ( 303) 418 106.1 5.1e-23 CCDS6675.1 CTSL gene_id:1514|Hs108|chr9 ( 333) 386 98.7 9.6e-21 CCDS10308.1 CTSH gene_id:1512|Hs108|chr15 ( 335) 383 98.0 1.6e-20 CCDS5986.1 CTSB gene_id:1508|Hs108|chr8 ( 339) 323 84.0 2.6e-16 CCDS4955.1 TINAG gene_id:27283|Hs108|chr6 ( 476) 297 78.1 2.3e-14 CCDS969.1 CTSK gene_id:1513|Hs108|chr1 ( 329) 286 75.4 9.8e-14 CCDS72745.1 TINAGL1 gene_id:64129|Hs108|chr1 ( 362) 277 73.3 4.5e-13 CCDS55586.1 TINAGL1 gene_id:64129|Hs108|chr1 ( 436) 277 73.4 5.3e-13 CCDS343.1 TINAGL1 gene_id:64129|Hs108|chr1 ( 467) 277 73.4 5.6e-13 CCDS8144.1 CTSF gene_id:8722|Hs108|chr11 ( 484) 257 68.8 1.5e-11 >>CCDS8282.1 CTSC gene_id:1075|Hs108|chr11 (463 aa) initn: 3206 init1: 3206 opt: 3206 Z-score: 4033.6 bits: 755.6 E(32554): 2.4e-218 Smith-Waterman score: 3206; 99.8% identity (99.8% similar) in 463 aa overlap (1-463:1-463) 10 20 30 40 50 60 pF1KB5 MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TMTGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINA :::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: CCDS82 TMTGWVHDVLGRNWACFTGKKVGTASENVYVNIAHLKNSQEKYSNRLYKYDHNFVKAINA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 IQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 GFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGM 370 380 390 400 410 420 430 440 450 460 pF1KB5 DYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL ::::::::::::::::::::::::::::::::::::::::::: CCDS82 DYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL 430 440 450 460 >>CCDS31654.1 CTSC gene_id:1075|Hs108|chr11 (137 aa) initn: 719 init1: 719 opt: 719 Z-score: 910.9 bits: 176.1 E(32554): 2e-44 Smith-Waterman score: 719; 100.0% identity (100.0% similar) in 106 aa overlap (1-106:1-106) 10 20 30 40 50 60 pF1KB5 MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNE :::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDFISHLFMQLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TMTGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINA CCDS31 TVGIYDLPHLRNKLVIK 130 >>CCDS44693.1 CTSC gene_id:1075|Hs108|chr11 (141 aa) initn: 719 init1: 719 opt: 719 Z-score: 910.7 bits: 176.1 E(32554): 2.1e-44 Smith-Waterman score: 719; 100.0% identity (100.0% similar) in 106 aa overlap (1-106:1-106) 10 20 30 40 50 60 pF1KB5 MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNE :::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDFISHLFMQLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TMTGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINA CCDS44 TVGIYDLPHLRNKLAMNRRWG 130 140 >>CCDS6723.1 CTSV gene_id:1515|Hs108|chr9 (334 aa) initn: 394 init1: 170 opt: 452 Z-score: 568.9 bits: 114.1 E(32554): 2.3e-25 Smith-Waterman score: 454; 31.3% identity (60.0% similar) in 335 aa overlap (128-454:26-329) 100 110 120 130 140 150 pF1KB5 DYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLK :. .: : ... :.:. . .. : CCDS67 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKA-THRRLYGANEEGWRRAVWEK 10 20 30 40 50 160 170 180 190 200 210 pF1KB5 NSQ--EKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRP : . : .... . :.:. :.::. : :.. . .: .: . .. :. : CCDS67 NMKMIELHNGEYSQGKHGFTMAMNAFGD----MTNEEFRQM-MG-CFRNQKFRKGKVFRE 60 70 80 90 100 220 230 240 250 260 270 pF1KB5 KPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILT :: .: :: : :::. .: .:.::.:: .::::..:.. : ::... . CCDS67 ---PL-------FLDLPKSVDWRK-KG--YVTPVKNQKQCGSCWAFSATGALEGQM--FR 110 120 130 140 150 280 290 300 310 320 330 pF1KB5 NNSQTPILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKM .... :: :..:.:: : :::.::: .. :: : .::...: ::. CCDS67 KTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKY 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB5 KEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTG . . .. . :. : ..:::: .. ::..::... ...: ::.::: CCDS67 RPENSVANDTGFTVVAP---GKEKALMK-AVATVGPISVAMDAGHSSFQFYKSGIYF--- 220 230 240 250 260 400 410 420 430 440 pF1KB5 LRDPFNPFELTNHAVLLVGYGTDSASGMD--YWIVKNSWGTGWGENGYFRIRRG-TDECA .: . .:.::.:::: ..:.. . ::.:::::: :: ::: .: . ...:. CCDS67 --EPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCG 270 280 290 300 310 320 450 460 pF1KB5 IESIAVAATPIPKL : . : CCDS67 IATAASYPNV 330 >>CCDS13474.1 CTSZ gene_id:1522|Hs108|chr20 (303 aa) initn: 300 init1: 131 opt: 418 Z-score: 526.8 bits: 106.1 E(32554): 5.1e-23 Smith-Waterman score: 418; 33.8% identity (60.1% similar) in 228 aa overlap (231-445:62-279) 210 220 230 240 250 pF1KB5 MIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQ---ASCGS :: ::::::: :.:..: .::: ::: CCDS13 TCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGS 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB5 CYSFASMGMLEARIRILTNNSQ-TPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGL :.. :: . . :: : ... . .:: :.:..:.. : .:::: : . ::.. :. CCDS13 CWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGN-AGSCEGGND-LSVWDYAHQHGI 100 110 120 130 140 320 330 340 350 360 pF1KB5 VEEACFPYTGTDSPCKMKEDC-----FRYYSSEYHY----VGGFYGGCNEALMKLELVHH .:.: : . :. : ..: :. . .: :: . . .. : :. . CCDS13 PDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN 150 160 170 180 190 200 370 380 390 400 410 420 pF1KB5 GPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKN ::.. .. . . . .: ::: . .. ::.: ..:.: ..: .::::.: CCDS13 GPISCGIMATERLANYTGGIYAE------YQDTTYINHVVSVAGWGI--SDGTEYWIVRN 210 220 230 240 250 260 430 440 450 460 pF1KB5 SWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL ::: ::: :..:: .: CCDS13 SWGEPWGERGWLRIVTSTYKDGKGARYNLAIEEHCTFGDPIV 270 280 290 300 >>CCDS6675.1 CTSL gene_id:1514|Hs108|chr9 (333 aa) initn: 341 init1: 165 opt: 386 Z-score: 485.9 bits: 98.7 E(32554): 9.6e-21 Smith-Waterman score: 432; 36.1% identity (63.5% similar) in 249 aa overlap (219-454:100-328) 190 200 210 220 230 240 pF1KB5 TYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHL--PTSWDWRNVHGINFV : ... :. : : : :::. .: .: CCDS66 KHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWRE-KG--YV 70 80 90 100 110 120 250 260 270 280 290 300 pF1KB5 SPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCS--QYAQGCEGGFPY .::.::..::::..:.. : ::.. .. .... :: :..:.:: : .::.::. . CCDS66 TPVKNQGQCGSCWAFSATGALEGQ--MFRKTGRLISLSEQNLVDCSGPQGNEGCNGGL-M 130 140 150 160 170 180 310 320 330 340 350 pF1KB5 LIAGKYAQDFG-LVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVG--GFYG--GCNEAL : .:.:: : : : .:: .:. :: :. .: .. :: ..:: CCDS66 DYAFQYVQDNGGLDSEESYPYEATEESCK--------YNPKYSVANDTGFVDIPKQEKAL 190 200 210 220 230 360 370 380 390 400 410 pF1KB5 MKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDS-- :: .. ::..::... ...:: ::.::: .: : .:.::.:::: .: CCDS66 MK-AVATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDMDHGVLVVGYGFESTE 240 250 260 270 280 420 430 440 450 460 pF1KB5 ASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAIESIAVAATPIPKL ... ::.:::::: :: .:: .. . ..:.: : : CCDS66 SDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 290 300 310 320 330 >>CCDS10308.1 CTSH gene_id:1512|Hs108|chr15 (335 aa) initn: 515 init1: 206 opt: 383 Z-score: 482.0 bits: 98.0 E(32554): 1.6e-20 Smith-Waterman score: 549; 35.5% identity (59.1% similar) in 313 aa overlap (153-461:40-333) 130 140 150 160 170 180 pF1KB5 TGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLKN-SQEKYSNRLYKYDHNFVKAINAI . : :. : :.: .:: . :. : ::: CCDS10 AGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRK-INA- 10 20 30 40 50 60 190 200 210 220 230 240 pF1KB5 QKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLT-AEIQQKILHLPTSWDWRNV ... . : : . .. :: :. .:. : .. . : : :::. CCDS10 HNNGNHTFKMALNQFS--DMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRK- 70 80 90 100 110 120 250 260 270 280 290 pF1KB5 HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQ--YAQGC .: ::::::.::..::::..:.. : ::. : : :.. . :. :..:.:.: .:: CCDS10 KG-NFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLS--LAEQQLVDCAQDFNNHGC 130 140 150 160 170 180 300 310 320 330 340 350 pF1KB5 EGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEA .::.: . :.. : .:: : :. ::.. . .. . . .: CCDS10 QGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIY----DEE 190 200 210 220 230 360 370 380 390 400 410 pF1KB5 LMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSAS : .. ..:.. :::: .::. :. ::: :. . .: . .::::: :::: . CCDS10 AMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK--TP-DKVNHAVLAVGYGEK--N 240 250 260 270 280 290 420 430 440 450 460 pF1KB5 GMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL :. ::::::::: :: :::: :.:: . :.. : :. ::: CCDS10 GIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLA--ACASYPIPLV 300 310 320 330 >>CCDS5986.1 CTSB gene_id:1508|Hs108|chr8 (339 aa) initn: 391 init1: 183 opt: 323 Z-score: 406.4 bits: 84.0 E(32554): 2.6e-16 Smith-Waterman score: 469; 31.3% identity (57.0% similar) in 335 aa overlap (156-459:14-330) 130 140 150 160 170 180 pF1KB5 VHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSW : :.. . : .. . ..:. .: . .: CCDS59 MWQLWASLCCLLVLANARSRPS--FHPLSDELVNYVNKRNTTW 10 20 30 40 190 200 210 220 230 240 pF1KB5 TATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNV-HGIN : .. .. .. . : : . ::: : . . . :.::.:.: :. CCDS59 QAG--HNFYNVDMSYLKRLCGTF---LGGPKP-PQRVMFTED-LKLPASFDAREQWPQCP 50 60 70 80 90 250 260 270 280 290 300 pF1KB5 FVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC--SQYAQGCEGGF .. .:.:.:::::..:... . :: : :: . .: .....: :. ..::.::. CCDS59 TIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGY 100 110 120 130 140 150 310 320 330 340 pF1KB5 PY----LIAGKYAQDFGLVEE--ACFPYT---------GTDSPCKMKED-------CFRY : . . : . :: : .: ::. :. :: . : : CCDS59 PAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 160 170 180 190 200 210 350 360 370 380 390 pF1KB5 YSSEY----HYVGGFYGGCN-EALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHH-TGLR :: : :: . :. : : . :. ..::. :: ::.::: ::.:.:.: :: CCDS59 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEM 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB5 DPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIA . .::. ..:.:... : ::.: :::.: ::.::.:.: :: :.:.::: . CCDS59 -------MGGHAIRILGWGVEN--GTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEV 280 290 300 310 320 460 pF1KB5 VAATPIPKL ::. : CCDS59 VAGIPRTDQYWEKI 330 >>CCDS4955.1 TINAG gene_id:27283|Hs108|chr6 (476 aa) initn: 448 init1: 172 opt: 297 Z-score: 371.5 bits: 78.1 E(32554): 2.3e-14 Smith-Waterman score: 453; 28.2% identity (55.3% similar) in 376 aa overlap (116-457:100-466) 90 100 110 120 130 140 pF1KB5 IIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFT-GKKVGT ..: : : .:: :.. CCDS49 CVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHTQPWYPEGCFKDGQHYEE 70 80 90 100 110 120 150 160 170 180 190 200 pF1KB5 AS---ENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDM .: :: :. ...: : :... .... .: . .::: .: .. .:: : CCDS49 GSVIKENC--NSCTCSGQQWKCSQHVCLVRSELIEQVNKGDYGWTAQNYSQFWGMTLED- 130 140 150 160 170 180 210 220 230 240 250 pF1KB5 IRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSP-----VRNQASCG : . .. :.:. ... ::.. : . .. : .: .:. CCDS49 -----GFKFRLGTLPPSPMLLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCA 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB5 SCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC-SQYAQGCEGGFPYLIAGKYAQDFG . ..:.. .. :: : ... : ::::...:: .. .::..: : : . : CCDS49 ASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSG-SIDRAWWYLRKRG 250 260 270 280 290 300 320 330 340 350 pF1KB5 LVEEACFPY----TGTDSPCKM--KED----------C---FRYYSSEYHYVGGFYGGCN :: .::.: ..:.. : : . : : . . :. . . : CCDS49 LVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 EALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHH-TGLRDPFNPF-ELTNHAVLLVGYGT :. . :....::. . ..: .::.::: :::.: :. . . .: .::: :.:.:: CCDS49 ETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGT 370 380 390 400 410 420 420 430 440 450 460 pF1KB5 -DSASGMD--YWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL .:.:. .::. :::: .::::::::: ::..: ::.. .:: CCDS49 LRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWGQLTSSDEP 430 440 450 460 470 >>CCDS969.1 CTSK gene_id:1513|Hs108|chr1 (329 aa) initn: 401 init1: 113 opt: 286 Z-score: 360.1 bits: 75.4 E(32554): 9.8e-14 Smith-Waterman score: 432; 31.4% identity (60.5% similar) in 306 aa overlap (158-454:39-324) 130 140 150 160 170 180 pF1KB5 DVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL-YKYDHNFVKAINAIQKSWT :. .. : :: .. . ... .:. .. : CCDS96 LPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYI-SIHNLEASLG 10 20 30 40 50 60 190 200 210 220 230 240 pF1KB5 ATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINF- . :: : :::: : .:. : .::. .. :..: :. : .... CCDS96 VHTY-ELAMNHLGDM--TSEEVVQKMTGLK-VPLSHSRSNDTLYIPE-WEGRAPDSVDYR 70 80 90 100 110 120 250 260 270 280 290 300 pF1KB5 ----VSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGG :.::.::..::::..:.:.: ::.... :.. . ::::..:.: . .:: :: CCDS96 KKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLN--LSPQNLVDCVSENDGCGGG 130 140 150 160 170 180 310 320 330 340 350 360 pF1KB5 FPYLIAGKYAQ-DFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALM . . : .:.: . :. : .::.: . : .. :. . : :: . CCDS96 Y-MTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIP--EG--NEKAL 190 200 210 220 230 370 380 390 400 410 pF1KB5 KLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASG : ... ::..::... .: :.::.:. : . ::::: :::: .. : CCDS96 KRAVARVGPVSVAIDASLTSFQFYSKGVYY-----DESCNSDNLNHAVLAVGYGIQK--G 240 250 260 270 280 420 430 440 450 460 pF1KB5 MDYWIVKNSWGTGWGENGYFRIRRGTDE-CAIESIAVAATPIPKL .::.::::: .::..::. . :. .. :.: ..: CCDS96 NKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 290 300 310 320 463 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:04:01 2016 done: Sat Nov 5 13:04:02 2016 Total Scan time: 2.930 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]