FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5555, 452 aa
1>>>pF1KB5555 452 - 452 aa - 452 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0577+/-0.000302; mu= 15.5258+/- 0.019
mean_var=102.7528+/-20.927, 0's: 0 Z-trim(118.9): 155 B-trim: 352 in 1/58
Lambda= 0.126525
statistics sampled from 32270 (32434) to 32270 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.38), width: 16
Scan time: 7.820
The best scores are: opt bits E(85289)
NP_002008 (OMIM: 193067) Friend leukemia integrati ( 452) 3132 582.0 1.1e-165
NP_001161153 (OMIM: 193067) Friend leukemia integr ( 419) 2923 543.8 3.2e-154
XP_011541003 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 2923 543.8 3.2e-154
XP_016872895 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 2923 543.8 3.2e-154
XP_016872894 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 2923 543.8 3.2e-154
NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 2610 486.6 4.8e-137
XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 2073 388.7 1.8e-107
NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 2057 385.8 1.3e-106
NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 2047 383.9 4.7e-106
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 1776 334.3 2.4e-91
NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 1731 326.2 9.1e-89
XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410) 1498 283.7 6.3e-76
NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 1274 242.8 1.2e-63
NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 1274 242.8 1.5e-63
NP_001129626 (OMIM: 165080) transcriptional regula ( 486) 1274 242.9 1.5e-63
NP_001230357 (OMIM: 165080) transcriptional regula ( 486) 1274 242.9 1.5e-63
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 1242 237.0 7.6e-62
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 1242 237.0 7.7e-62
XP_011527789 (OMIM: 165080) PREDICTED: transcripti ( 259) 829 161.4 2.6e-39
NP_001230361 (OMIM: 165080) transcriptional regula ( 317) 829 161.5 3e-39
NP_001278320 (OMIM: 165080) transcriptional regula ( 325) 829 161.5 3.1e-39
NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 623 123.8 5e-28
NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 465 94.9 2.3e-19
XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 465 95.1 3.7e-19
NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 465 95.1 3.9e-19
XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 465 95.2 3.9e-19
XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 465 95.2 4.1e-19
NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 465 95.2 4.2e-19
XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 465 95.2 4.2e-19
XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 465 95.2 4.4e-19
XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 461 94.4 6.7e-19
XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 461 94.4 6.7e-19
NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 461 94.4 6.7e-19
NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 461 94.5 8.2e-19
NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 425 87.8 5.2e-17
XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 425 87.8 5.7e-17
XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 425 87.8 6e-17
NP_006485 (OMIM: 600775,611888) ETS domain-contain ( 548) 410 85.2 4.8e-16
XP_006711273 (OMIM: 164873) PREDICTED: ETS translo ( 512) 401 83.5 1.4e-15
NP_001138784 (OMIM: 164873) ETS translocation vari ( 512) 401 83.5 1.4e-15
XP_011527822 (OMIM: 600609) PREDICTED: GA-binding ( 454) 400 83.3 1.5e-15
NP_002031 (OMIM: 600609) GA-binding protein alpha ( 454) 400 83.3 1.5e-15
NP_001184226 (OMIM: 600609) GA-binding protein alp ( 454) 400 83.3 1.5e-15
XP_005260995 (OMIM: 600609) PREDICTED: GA-binding ( 454) 400 83.3 1.5e-15
XP_011527823 (OMIM: 600609) PREDICTED: GA-binding ( 454) 400 83.3 1.5e-15
XP_016883802 (OMIM: 600609) PREDICTED: GA-binding ( 454) 400 83.3 1.5e-15
NP_001287903 (OMIM: 609358) ETS translocation vari ( 249) 395 82.2 1.8e-15
XP_011524926 (OMIM: 609358) PREDICTED: ETS translo ( 249) 395 82.2 1.8e-15
NP_055024 (OMIM: 609358) ETS translocation variant ( 342) 395 82.3 2.2e-15
XP_016881961 (OMIM: 609358) PREDICTED: ETS translo ( 343) 395 82.3 2.2e-15
>>NP_002008 (OMIM: 193067) Friend leukemia integration 1 (452 aa)
initn: 3132 init1: 3132 opt: 3132 Z-score: 3095.4 bits: 582.0 E(85289): 1.1e-165
Smith-Waterman score: 3132; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452)
10 20 30 40 50 60
pF1KB5 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 DFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAAS
370 380 390 400 410 420
430 440 450
pF1KB5 QYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
::::::::::::::::::::::::::::::::
NP_002 QYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
430 440 450
>>NP_001161153 (OMIM: 193067) Friend leukemia integratio (419 aa)
initn: 2923 init1: 2923 opt: 2923 Z-score: 2889.7 bits: 543.8 E(85289): 3.2e-154
Smith-Waterman score: 2923; 100.0% identity (100.0% similar) in 419 aa overlap (34-452:1-419)
10 20 30 40 50 60
pF1KB5 TIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVR
::::::::::::::::::::::::::::::
NP_001 MTASGSPDYGQPHKINPLPPQQEWINQPVR
10 20 30
70 80 90 100 110 120
pF1KB5 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW
340 350 360 370 380 390
430 440 450
pF1KB5 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY
:::::::::::::::::::::::::::::
NP_001 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY
400 410
>>XP_011541003 (OMIM: 193067) PREDICTED: Friend leukemia (419 aa)
initn: 2923 init1: 2923 opt: 2923 Z-score: 2889.7 bits: 543.8 E(85289): 3.2e-154
Smith-Waterman score: 2923; 100.0% identity (100.0% similar) in 419 aa overlap (34-452:1-419)
10 20 30 40 50 60
pF1KB5 TIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVR
::::::::::::::::::::::::::::::
XP_011 MTASGSPDYGQPHKINPLPPQQEWINQPVR
10 20 30
70 80 90 100 110 120
pF1KB5 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW
340 350 360 370 380 390
430 440 450
pF1KB5 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY
:::::::::::::::::::::::::::::
XP_011 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY
400 410
>>XP_016872895 (OMIM: 193067) PREDICTED: Friend leukemia (419 aa)
initn: 2923 init1: 2923 opt: 2923 Z-score: 2889.7 bits: 543.8 E(85289): 3.2e-154
Smith-Waterman score: 2923; 100.0% identity (100.0% similar) in 419 aa overlap (34-452:1-419)
10 20 30 40 50 60
pF1KB5 TIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVR
::::::::::::::::::::::::::::::
XP_016 MTASGSPDYGQPHKINPLPPQQEWINQPVR
10 20 30
70 80 90 100 110 120
pF1KB5 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW
340 350 360 370 380 390
430 440 450
pF1KB5 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY
:::::::::::::::::::::::::::::
XP_016 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY
400 410
>>XP_016872894 (OMIM: 193067) PREDICTED: Friend leukemia (419 aa)
initn: 2923 init1: 2923 opt: 2923 Z-score: 2889.7 bits: 543.8 E(85289): 3.2e-154
Smith-Waterman score: 2923; 100.0% identity (100.0% similar) in 419 aa overlap (34-452:1-419)
10 20 30 40 50 60
pF1KB5 TIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVR
::::::::::::::::::::::::::::::
XP_016 MTASGSPDYGQPHKINPLPPQQEWINQPVR
10 20 30
70 80 90 100 110 120
pF1KB5 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW
340 350 360 370 380 390
430 440 450
pF1KB5 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY
:::::::::::::::::::::::::::::
XP_016 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY
400 410
>>NP_001257939 (OMIM: 193067) Friend leukemia integratio (386 aa)
initn: 2610 init1: 2610 opt: 2610 Z-score: 2581.4 bits: 486.6 E(85289): 4.8e-137
Smith-Waterman score: 2610; 99.7% identity (100.0% similar) in 377 aa overlap (76-452:10-386)
50 60 70 80 90 100
pF1KB5 HKINPLPPQQEWINQPVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSY
.:::::::::::::::::::::::::::::
NP_001 MEGGLAGERARESPVDCSVSKCSKLVGGGESNPMNYNSY
10 20 30
110 120 130 140 150 160
pF1KB5 MDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGK
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 ELCKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELCKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB5 RRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQ
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB5 FLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB5 NIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHP
280 290 300 310 320 330
410 420 430 440 450
pF1KB5 SSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
340 350 360 370 380
>>XP_016883776 (OMIM: 165080) PREDICTED: transcriptional (459 aa)
initn: 1813 init1: 1210 opt: 2073 Z-score: 2050.6 bits: 388.7 E(85289): 1.8e-107
Smith-Waterman score: 2073; 66.9% identity (85.0% similar) in 453 aa overlap (5-452:12-459)
10 20 30 40 50
pF1KB5 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPP
:::::::::.:::::. :::. :: :..::::.: :::: :..: :
XP_016 MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTP-HLAKTEMTASSSSDYGQTSKMSPRVP
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 QQEWINQP-VRVNVKREYD--HMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKN
::.:..:: .::..: : . ..::::.:: .:::.: .:.::. .. :::.:::.::.
XP_016 QQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 GPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKM
::: ::::::::::::::::::. .:::::::::.:::.: ... .:::.::::::::
XP_016 MPPP-NMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKM
120 130 140 150 160 170
180 190 200 210 220
pF1KB5 NKEDFLRATTLYNTEVLLSHLSYLRE--SSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRG
.:.:: : : ::...::::: :::: .... ::. . . ..:.... : :. ::.
XP_016 TKDDFQRLTPSYNADILLSHLHYLRERGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 AWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLL
:: .. . ... . .:. :. .:::: ::::::::::::::::::::::::::::
XP_016 AWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 ELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIM
::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIM
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 TKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSM
::::::::::::::::::::::::: :::.::::::. :: ::::: ::.::: ::: ..
XP_016 TKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPAL
360 370 380 390 400 410
410 420 430 440 450
pF1KB5 PVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
::::::::.: . ::.::::::::: : :..:.:::::.::
XP_016 PVTSSSFFAAPNPYWNSPTGGIYPNT---RLPTSHMPSHLGTYY
420 430 440 450
>>NP_001317954 (OMIM: 165080) transcriptional regulator (455 aa)
initn: 1951 init1: 1172 opt: 2057 Z-score: 2034.9 bits: 385.8 E(85289): 1.3e-106
Smith-Waterman score: 2057; 67.0% identity (84.3% similar) in 460 aa overlap (1-452:1-455)
10 20 30 40 50 60
pF1KB5 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ
: .::::::::::.:::::. :::. :: :..::::.: :::: :..: :::.:..:
NP_001 MASTIKEALSVVSEDQSLFECAYGTP-HLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQ
10 20 30 40 50
70 80 90 100 110
pF1KB5 P-VRVNVKREYD--HMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNM
: .::..: : . ..::::.:: .:::.: .:.::. .. :::.:::.::. ::: ::
NP_001 PPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPP-NM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 TTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLR
::::::::::::::::. .:::::::::.:::.: ... .:::.::::::::.:.:: :
NP_001 TTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 ATTLYNTEVLLSHLSYLRESSL--LAYNTTSHTDQSS-RL--SVKEDPSYDSVRRGAWGN
: ::...::::: ::::. : :. . .... :.: :: . . : :. ::.:: .
NP_001 LTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTDLPYEPPRRSAWTG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 NMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLS
. . ... . .:. :. .:::: ::::::::::::::::::::::::::::::::
NP_001 HGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 DSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVH
::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVH
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 GKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTS
::::::::::::::::::::: :::.::::::. :: ::::: ::.::: ::: ..::::
NP_001 GKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTS
360 370 380 390 400 410
420 430 440 450
pF1KB5 SSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
::::.: . ::.::::::::: : :..:.:::::.::
NP_001 SSFFAAPNPYWNSPTGGIYPNT---RLPTSHMPSHLGTYY
420 430 440 450
>>NP_004440 (OMIM: 165080) transcriptional regulator ERG (462 aa)
initn: 1951 init1: 1172 opt: 2047 Z-score: 2025.0 bits: 383.9 E(85289): 4.7e-106
Smith-Waterman score: 2047; 67.0% identity (83.8% similar) in 457 aa overlap (5-452:12-462)
10 20 30 40 50
pF1KB5 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPP
:::::::::.:::::. :::. :: :..::::.: :::: :..: :
NP_004 MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTP-HLAKTEMTASSSSDYGQTSKMSPRVP
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 QQEWINQP-VRVNVKREYD--HMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKN
::.:..:: .::..: : . ..::::.:: .:::.: .:.::. .. :::.:::.::.
NP_004 QQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 GPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKM
::: ::::::::::::::::::. .:::::::::.:::.: ... .:::.::::::::
NP_004 MPPP-NMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKM
120 130 140 150 160 170
180 190 200 210 220
pF1KB5 NKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQ----SSRL--SVKEDPSYDS
.:.:: : : ::...::::: ::::. : . :.. .:. : :: . . : :.
NP_004 TKDDFQRLTPSYNADILLSHLHYLRETPL-PHLTSDDVDKALQNSPRLMHARNTDLPYEP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 VRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLW
::.:: .. . ... . .:. :. .:::: ::::::::::::::::::::::::
NP_004 PRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLW
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 QFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYD
::::::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYD
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 KNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPH
::::::::::::::::::::::::::::: :::.::::::. :: ::::: ::.::: ::
NP_004 KNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPH
360 370 380 390 400 410
410 420 430 440 450
pF1KB5 PSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
: ..::::::::.: . ::.::::::::: : :..:.:::::.::
NP_004 PPALPVTSSSFFAAPNPYWNSPTGGIYPNT---RLPTSHMPSHLGTYY
420 430 440 450 460
>>NP_001257941 (OMIM: 193067) Friend leukemia integratio (259 aa)
initn: 1776 init1: 1776 opt: 1776 Z-score: 1761.1 bits: 334.3 E(85289): 2.4e-91
Smith-Waterman score: 1776; 100.0% identity (100.0% similar) in 255 aa overlap (198-452:5-259)
170 180 190 200 210 220
pF1KB5 CKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRR
::::::::::::::::::::::::::::::
NP_001 MDPGSLLAYNTTSHTDQSSRLSVKEDPSYDSVRR
10 20 30
230 240 250 260 270 280
pF1KB5 GAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFL
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB5 LELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNI
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB5 MTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSS
160 170 180 190 200 210
410 420 430 440 450
pF1KB5 MPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
220 230 240 250
452 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:34:11 2016 done: Thu Nov 3 17:34:12 2016
Total Scan time: 7.820 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]