FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5555, 452 aa 1>>>pF1KB5555 452 - 452 aa - 452 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0577+/-0.000302; mu= 15.5258+/- 0.019 mean_var=102.7528+/-20.927, 0's: 0 Z-trim(118.9): 155 B-trim: 352 in 1/58 Lambda= 0.126525 statistics sampled from 32270 (32434) to 32270 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.38), width: 16 Scan time: 7.820 The best scores are: opt bits E(85289) NP_002008 (OMIM: 193067) Friend leukemia integrati ( 452) 3132 582.0 1.1e-165 NP_001161153 (OMIM: 193067) Friend leukemia integr ( 419) 2923 543.8 3.2e-154 XP_011541003 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 2923 543.8 3.2e-154 XP_016872895 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 2923 543.8 3.2e-154 XP_016872894 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 2923 543.8 3.2e-154 NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 2610 486.6 4.8e-137 XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 2073 388.7 1.8e-107 NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 2057 385.8 1.3e-106 NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 2047 383.9 4.7e-106 NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 1776 334.3 2.4e-91 NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 1731 326.2 9.1e-89 XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410) 1498 283.7 6.3e-76 NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 1274 242.8 1.2e-63 NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 1274 242.8 1.5e-63 NP_001129626 (OMIM: 165080) transcriptional regula ( 486) 1274 242.9 1.5e-63 NP_001230357 (OMIM: 165080) transcriptional regula ( 486) 1274 242.9 1.5e-63 XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 1242 237.0 7.6e-62 XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 1242 237.0 7.7e-62 XP_011527789 (OMIM: 165080) PREDICTED: transcripti ( 259) 829 161.4 2.6e-39 NP_001230361 (OMIM: 165080) transcriptional regula ( 317) 829 161.5 3e-39 NP_001278320 (OMIM: 165080) transcriptional regula ( 325) 829 161.5 3.1e-39 NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 623 123.8 5e-28 NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 465 94.9 2.3e-19 XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 465 95.1 3.7e-19 NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 465 95.1 3.9e-19 XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 465 95.2 3.9e-19 XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 465 95.2 4.1e-19 NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 465 95.2 4.2e-19 XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 465 95.2 4.2e-19 XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 465 95.2 4.4e-19 XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 461 94.4 6.7e-19 XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 461 94.4 6.7e-19 NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 461 94.4 6.7e-19 NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 461 94.5 8.2e-19 NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 425 87.8 5.2e-17 XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 425 87.8 5.7e-17 XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 425 87.8 6e-17 NP_006485 (OMIM: 600775,611888) ETS domain-contain ( 548) 410 85.2 4.8e-16 XP_006711273 (OMIM: 164873) PREDICTED: ETS translo ( 512) 401 83.5 1.4e-15 NP_001138784 (OMIM: 164873) ETS translocation vari ( 512) 401 83.5 1.4e-15 XP_011527822 (OMIM: 600609) PREDICTED: GA-binding ( 454) 400 83.3 1.5e-15 NP_002031 (OMIM: 600609) GA-binding protein alpha ( 454) 400 83.3 1.5e-15 NP_001184226 (OMIM: 600609) GA-binding protein alp ( 454) 400 83.3 1.5e-15 XP_005260995 (OMIM: 600609) PREDICTED: GA-binding ( 454) 400 83.3 1.5e-15 XP_011527823 (OMIM: 600609) PREDICTED: GA-binding ( 454) 400 83.3 1.5e-15 XP_016883802 (OMIM: 600609) PREDICTED: GA-binding ( 454) 400 83.3 1.5e-15 NP_001287903 (OMIM: 609358) ETS translocation vari ( 249) 395 82.2 1.8e-15 XP_011524926 (OMIM: 609358) PREDICTED: ETS translo ( 249) 395 82.2 1.8e-15 NP_055024 (OMIM: 609358) ETS translocation variant ( 342) 395 82.3 2.2e-15 XP_016881961 (OMIM: 609358) PREDICTED: ETS translo ( 343) 395 82.3 2.2e-15 >>NP_002008 (OMIM: 193067) Friend leukemia integration 1 (452 aa) initn: 3132 init1: 3132 opt: 3132 Z-score: 3095.4 bits: 582.0 E(85289): 1.1e-165 Smith-Waterman score: 3132; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB5 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 DFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAAS 370 380 390 400 410 420 430 440 450 pF1KB5 QYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY :::::::::::::::::::::::::::::::: NP_002 QYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY 430 440 450 >>NP_001161153 (OMIM: 193067) Friend leukemia integratio (419 aa) initn: 2923 init1: 2923 opt: 2923 Z-score: 2889.7 bits: 543.8 E(85289): 3.2e-154 Smith-Waterman score: 2923; 100.0% identity (100.0% similar) in 419 aa overlap (34-452:1-419) 10 20 30 40 50 60 pF1KB5 TIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVR :::::::::::::::::::::::::::::: NP_001 MTASGSPDYGQPHKINPLPPQQEWINQPVR 10 20 30 70 80 90 100 110 120 pF1KB5 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW 340 350 360 370 380 390 430 440 450 pF1KB5 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY ::::::::::::::::::::::::::::: NP_001 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY 400 410 >>XP_011541003 (OMIM: 193067) PREDICTED: Friend leukemia (419 aa) initn: 2923 init1: 2923 opt: 2923 Z-score: 2889.7 bits: 543.8 E(85289): 3.2e-154 Smith-Waterman score: 2923; 100.0% identity (100.0% similar) in 419 aa overlap (34-452:1-419) 10 20 30 40 50 60 pF1KB5 TIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVR :::::::::::::::::::::::::::::: XP_011 MTASGSPDYGQPHKINPLPPQQEWINQPVR 10 20 30 70 80 90 100 110 120 pF1KB5 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW 340 350 360 370 380 390 430 440 450 pF1KB5 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY ::::::::::::::::::::::::::::: XP_011 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY 400 410 >>XP_016872895 (OMIM: 193067) PREDICTED: Friend leukemia (419 aa) initn: 2923 init1: 2923 opt: 2923 Z-score: 2889.7 bits: 543.8 E(85289): 3.2e-154 Smith-Waterman score: 2923; 100.0% identity (100.0% similar) in 419 aa overlap (34-452:1-419) 10 20 30 40 50 60 pF1KB5 TIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVR :::::::::::::::::::::::::::::: XP_016 MTASGSPDYGQPHKINPLPPQQEWINQPVR 10 20 30 70 80 90 100 110 120 pF1KB5 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW 340 350 360 370 380 390 430 440 450 pF1KB5 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY ::::::::::::::::::::::::::::: XP_016 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY 400 410 >>XP_016872894 (OMIM: 193067) PREDICTED: Friend leukemia (419 aa) initn: 2923 init1: 2923 opt: 2923 Z-score: 2889.7 bits: 543.8 E(85289): 3.2e-154 Smith-Waterman score: 2923; 100.0% identity (100.0% similar) in 419 aa overlap (34-452:1-419) 10 20 30 40 50 60 pF1KB5 TIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVR :::::::::::::::::::::::::::::: XP_016 MTASGSPDYGQPHKINPLPPQQEWINQPVR 10 20 30 70 80 90 100 110 120 pF1KB5 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPP 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB5 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFH 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB5 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYW 340 350 360 370 380 390 430 440 450 pF1KB5 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY ::::::::::::::::::::::::::::: XP_016 TSPTGGIYPNPNVPRHPNTHVPSHLGSYY 400 410 >>NP_001257939 (OMIM: 193067) Friend leukemia integratio (386 aa) initn: 2610 init1: 2610 opt: 2610 Z-score: 2581.4 bits: 486.6 E(85289): 4.8e-137 Smith-Waterman score: 2610; 99.7% identity (100.0% similar) in 377 aa overlap (76-452:10-386) 50 60 70 80 90 100 pF1KB5 HKINPLPPQQEWINQPVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSY .::::::::::::::::::::::::::::: NP_001 MEGGLAGERARESPVDCSVSKCSKLVGGGESNPMNYNSY 10 20 30 110 120 130 140 150 160 pF1KB5 MDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 ELCKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELCKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSV 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 RRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQ 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 FLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDK 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 NIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHP 280 290 300 310 320 330 410 420 430 440 450 pF1KB5 SSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY 340 350 360 370 380 >>XP_016883776 (OMIM: 165080) PREDICTED: transcriptional (459 aa) initn: 1813 init1: 1210 opt: 2073 Z-score: 2050.6 bits: 388.7 E(85289): 1.8e-107 Smith-Waterman score: 2073; 66.9% identity (85.0% similar) in 453 aa overlap (5-452:12-459) 10 20 30 40 50 pF1KB5 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPP :::::::::.:::::. :::. :: :..::::.: :::: :..: : XP_016 MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTP-HLAKTEMTASSSSDYGQTSKMSPRVP 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 QQEWINQP-VRVNVKREYD--HMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKN ::.:..:: .::..: : . ..::::.:: .:::.: .:.::. .. :::.:::.::. XP_016 QQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 GPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKM ::: ::::::::::::::::::. .:::::::::.:::.: ... .:::.:::::::: XP_016 MPPP-NMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKM 120 130 140 150 160 170 180 190 200 210 220 pF1KB5 NKEDFLRATTLYNTEVLLSHLSYLRE--SSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRG .:.:: : : ::...::::: :::: .... ::. . . ..:.... : :. ::. XP_016 TKDDFQRLTPSYNADILLSHLHYLRERGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRS 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 AWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLL :: .. . ... . .:. :. .:::: :::::::::::::::::::::::::::: XP_016 AWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLL 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 ELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIM ::::::.:.::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIM 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 TKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSM ::::::::::::::::::::::::: :::.::::::. :: ::::: ::.::: ::: .. XP_016 TKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPAL 360 370 380 390 400 410 410 420 430 440 450 pF1KB5 PVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY ::::::::.: . ::.::::::::: : :..:.:::::.:: XP_016 PVTSSSFFAAPNPYWNSPTGGIYPNT---RLPTSHMPSHLGTYY 420 430 440 450 >>NP_001317954 (OMIM: 165080) transcriptional regulator (455 aa) initn: 1951 init1: 1172 opt: 2057 Z-score: 2034.9 bits: 385.8 E(85289): 1.3e-106 Smith-Waterman score: 2057; 67.0% identity (84.3% similar) in 460 aa overlap (1-452:1-455) 10 20 30 40 50 60 pF1KB5 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ : .::::::::::.:::::. :::. :: :..::::.: :::: :..: :::.:..: NP_001 MASTIKEALSVVSEDQSLFECAYGTP-HLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQ 10 20 30 40 50 70 80 90 100 110 pF1KB5 P-VRVNVKREYD--HMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNM : .::..: : . ..::::.:: .:::.: .:.::. .. :::.:::.::. ::: :: NP_001 PPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPP-NM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 TTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLR ::::::::::::::::. .:::::::::.:::.: ... .:::.::::::::.:.:: : NP_001 TTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 ATTLYNTEVLLSHLSYLRESSL--LAYNTTSHTDQSS-RL--SVKEDPSYDSVRRGAWGN : ::...::::: ::::. : :. . .... :.: :: . . : :. ::.:: . NP_001 LTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTDLPYEPPRRSAWTG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 NMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLS . . ... . .:. :. .:::: :::::::::::::::::::::::::::::::: NP_001 HGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 DSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVH ::.:.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVH 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 GKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTS ::::::::::::::::::::: :::.::::::. :: ::::: ::.::: ::: ..:::: NP_001 GKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTS 360 370 380 390 400 410 420 430 440 450 pF1KB5 SSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY ::::.: . ::.::::::::: : :..:.:::::.:: NP_001 SSFFAAPNPYWNSPTGGIYPNT---RLPTSHMPSHLGTYY 420 430 440 450 >>NP_004440 (OMIM: 165080) transcriptional regulator ERG (462 aa) initn: 1951 init1: 1172 opt: 2047 Z-score: 2025.0 bits: 383.9 E(85289): 4.7e-106 Smith-Waterman score: 2047; 67.0% identity (83.8% similar) in 457 aa overlap (5-452:12-462) 10 20 30 40 50 pF1KB5 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPP :::::::::.:::::. :::. :: :..::::.: :::: :..: : NP_004 MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTP-HLAKTEMTASSSSDYGQTSKMSPRVP 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 QQEWINQP-VRVNVKREYD--HMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKN ::.:..:: .::..: : . ..::::.:: .:::.: .:.::. .. :::.:::.::. NP_004 QQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 GPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKM ::: ::::::::::::::::::. .:::::::::.:::.: ... .:::.:::::::: NP_004 MPPP-NMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKM 120 130 140 150 160 170 180 190 200 210 220 pF1KB5 NKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQ----SSRL--SVKEDPSYDS .:.:: : : ::...::::: ::::. : . :.. .:. : :: . . : :. NP_004 TKDDFQRLTPSYNADILLSHLHYLRETPL-PHLTSDDVDKALQNSPRLMHARNTDLPYEP 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 VRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLW ::.:: .. . ... . .:. :. .:::: :::::::::::::::::::::::: NP_004 PRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLW 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 QFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYD ::::::::::.:.::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYD 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 KNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPH ::::::::::::::::::::::::::::: :::.::::::. :: ::::: ::.::: :: NP_004 KNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPH 360 370 380 390 400 410 410 420 430 440 450 pF1KB5 PSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY : ..::::::::.: . ::.::::::::: : :..:.:::::.:: NP_004 PPALPVTSSSFFAAPNPYWNSPTGGIYPNT---RLPTSHMPSHLGTYY 420 430 440 450 460 >>NP_001257941 (OMIM: 193067) Friend leukemia integratio (259 aa) initn: 1776 init1: 1776 opt: 1776 Z-score: 1761.1 bits: 334.3 E(85289): 2.4e-91 Smith-Waterman score: 1776; 100.0% identity (100.0% similar) in 255 aa overlap (198-452:5-259) 170 180 190 200 210 220 pF1KB5 CKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRR :::::::::::::::::::::::::::::: NP_001 MDPGSLLAYNTTSHTDQSSRLSVKEDPSYDSVRR 10 20 30 230 240 250 260 270 280 pF1KB5 GAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFL 40 50 60 70 80 90 290 300 310 320 330 340 pF1KB5 LELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNI 100 110 120 130 140 150 350 360 370 380 390 400 pF1KB5 MTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSS 160 170 180 190 200 210 410 420 430 440 450 pF1KB5 MPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY ::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY 220 230 240 250 452 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 17:34:11 2016 done: Thu Nov 3 17:34:12 2016 Total Scan time: 7.820 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]