Result of FASTA (omim) for
pF1KB5556
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5556, 331 aa
1>>>pF1KB5556 331 - 331 aa - 331 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8633+/-0.000385; mu= 4.1228+/- 0.024
mean_var=288.0361+/-57.179, 0's: 0 Z-trim(122.6): 31 B-trim: 470 in 1/55
Lambda= 0.075570
statistics sampled from 41055 (41092) to 41055 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.482), width: 16
Scan time: 9.740
The best scores are: opt bits E(85289)
NP_002219 (OMIM: 165160) transcription factor AP-1 ( 331) 2171 249.3 8.6e-66
NP_005345 (OMIM: 165162) transcription factor jun- ( 347) 731 92.3 1.6e-18
NP_001273897 (OMIM: 165162) transcription factor j ( 304) 728 91.9 1.9e-18
NP_002220 (OMIM: 165161) transcription factor jun- ( 347) 711 90.1 7.3e-18
NP_001123532 (OMIM: 606371) cyclic AMP-dependent t ( 462) 264 41.5 0.0042
XP_016874211 (OMIM: 606371) PREDICTED: cyclic AMP- ( 483) 264 41.5 0.0043
NP_006847 (OMIM: 606371) cyclic AMP-dependent tran ( 483) 264 41.5 0.0043
XP_005268644 (OMIM: 606371) PREDICTED: cyclic AMP- ( 483) 264 41.5 0.0043
>>NP_002219 (OMIM: 165160) transcription factor AP-1 [Ho (331 aa)
initn: 2171 init1: 2171 opt: 2171 Z-score: 1302.2 bits: 249.3 E(85289): 8.6e-66
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331)
10 20 30 40 50 60
pF1KB5 MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANM
250 260 270 280 290 300
310 320 330
pF1KB5 LREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
:::::::::::::::::::::::::::::::
NP_002 LREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
310 320 330
>>NP_005345 (OMIM: 165162) transcription factor jun-D is (347 aa)
initn: 837 init1: 502 opt: 731 Z-score: 453.4 bits: 92.3 E(85289): 1.6e-18
Smith-Waterman score: 989; 53.0% identity (70.7% similar) in 362 aa overlap (5-331:1-347)
10 20 30 40
pF1KB5 MTAKMETTFYDDALNASFLPSESGPYG-YSNPKIL---------------KQSMTLNLAD
::: :: : ... . :: : ...: : :...::.:..
NP_005 METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSE
10 20 30 40 50
50 60 70 80
pF1KB5 PVGS-LKPH-------LRAKNSD-------LLTSPDVGLLKLASPELERLIIQSSNGHIT
:.. ::: ::: .. ::.:::.::::::::::::::::: :: .:
NP_005 QVAAALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQS-NGLVT
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB5 TTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVNGAGMVAPAVAS
:::: .::: :: ...:.. ::::::.:: .::.:: : . ..:: . .:: .:. .
NP_005 TTPTSSQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAG--GPS--G
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB5 VAGGSGSGGFSASLHSEP--PVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQQQP
.: ::. : : . : :::::::.. :: ::: ::: .:: :.: :
NP_005 TATGSAPPGELAPAAAAPEAPVYANLSSYAGGA----GGAG--GAATVAFAAEPVPFPPP
180 190 200 210 220
210 220 230 240 250 260
pF1KB5 PHHLPQQMPVQHPRLQALKEEPQTVPEMP--GETPPLSPIDMESQERIKAERKRMRNRIA
: : . ::: :::.::::::..: ::.::::::::..::::::::::.:::::
NP_005 PP--PGALG--PPRLAALKDEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB5 ASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLT
::::::::::::.::::::::::.::.::::::..::::::::::::..::::::::.
NP_005 ASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQ
290 300 310 320 330 340
330
pF1KB5 QQLQTF
.:. ..
NP_005 HQVPAY
>>NP_001273897 (OMIM: 165162) transcription factor jun-D (304 aa)
initn: 837 init1: 502 opt: 728 Z-score: 452.4 bits: 91.9 E(85289): 1.9e-18
Smith-Waterman score: 981; 57.3% identity (75.3% similar) in 316 aa overlap (35-331:4-304)
10 20 30 40 50
pF1KB5 METTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGS-LKPH-------LRAK
:...::.:.. :.. ::: :::
NP_001 MMKKDALTLSLSEQVAAALKPAAAPPPTPLRAD
10 20 30
60 70 80 90 100
pF1KB5 NSD-------LLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEG
.. ::.:::.::::::::::::::::: :: .::::: .::: :: ...:..
NP_001 GAPSAAPPDGLLASPDLGLLKLASPELERLIIQS-NGLVTTTPTSSQFLYPKVAASEEQE
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 FAEGFVRALAELHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEP--
::::::.:: .::.:: : . ..:: . .:: .:. ..: ::. : : . :
NP_001 FAEGFVKALEDLHKQNQLGAGAAAAAAAAAAG--GPS--GTATGSAPPGELAPAAAAPEA
100 110 120 130 140
170 180 190 200 210 220
pF1KB5 PVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKE
:::::::.. :: ::: ::: .:: :.: :: : . ::: :::.
NP_001 PVYANLSSYAGGA----GGAG--GAATVAFAAEPVPFPPPPP--PGAL--GPPRLAALKD
150 160 170 180 190
230 240 250 260 270 280
pF1KB5 EPQTVPEMP--GETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVK
::::::..: ::.::::::::..::::::::::.:::::::::::::::::.:::::::
NP_001 EPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVK
200 210 220 230 240 250
290 300 310 320 330
pF1KB5 TLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
:::.::.::::::..::::::::::::..::::::::. .:. ..
NP_001 TLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY
260 270 280 290 300
>>NP_002220 (OMIM: 165161) transcription factor jun-B [H (347 aa)
initn: 876 init1: 454 opt: 711 Z-score: 441.7 bits: 90.1 E(85289): 7.3e-18
Smith-Waterman score: 859; 47.7% identity (68.2% similar) in 365 aa overlap (1-331:1-347)
10 20 30 40 50
pF1KB5 MTAKMETTFY-DDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLK-PHLRAKNS
: .::: :: ::. .:. : . . :.:: :...::::: ::: : :. .
NP_002 MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGP
10 20 30 40 50 60
60 70 80 90 100
pF1KB5 D------LLTSP--DVGL-LKLASPELERLIIQSSNGHITTTPTPT-QFLCPKN------
. ... :.: ::::: ::::::. .::: ::::::: :.. :..
NP_002 EGGGGGSYFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGG
70 80 90 100 110 120
110 120 130 140 150
pF1KB5 -------VTDEQEGFAEGFVRALAELHSQN--TLPSVTSAAQPVNGAGMVAPAVASVAGG
::.::::::.:::.:: .::..: : :.:. :: ::
NP_002 AGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSL------GATGGPPA-------
130 140 150 160
160 170 180 190 200
pF1KB5 SGSGGFSASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQ--QQPPH--
: :: :. ::::.:::...:.. ::::.. . :. : ..:. . . ::
NP_002 -GPGGVYAG-PEPPPVYTNLSSYSPASASSGGAGAAVGT-GSSYPTTTISYLPHAPPFAG
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB5 -HLPQQMPVQHPRLQALKEEPQTVPEMPGE--TPPLSPIDMESQERIKAERKRMRNRIAA
: : :. . . ...::::::::: .. :::.:::.::.:::::.::::.:::.::
NP_002 GH-PAQLGLGRGA-STFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB5 SKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQ
.::::::::::::::.:::::::.:. :.:::..:::::::::::::.::..::::.:
NP_002 TKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGV
290 300 310 320 330 340
330
pF1KB5 QLQTF
. ..:
NP_002 KGHAF
>>NP_001123532 (OMIM: 606371) cyclic AMP-dependent trans (462 aa)
initn: 263 init1: 166 opt: 264 Z-score: 176.8 bits: 41.5 E(85289): 0.0042
Smith-Waterman score: 286; 27.8% identity (53.8% similar) in 327 aa overlap (23-327:91-384)
10 20 30 40 50
pF1KB5 MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPH
.:: .: :. .. .. .:: . :.
NP_001 CEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPST--PDIKIKEEEPVEEVTPK
70 80 90 100 110
60 70 80 90 100 110
pF1KB5 LRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAE
:...: ... .: :. . . : : :.::. . ...: :
NP_001 -----PVLISTPTPTIVRPGSLPLH---LGYDPLH-PTLPSPTSVITQAPPSNRQMGSPT
120 130 140 150 160
120 130 140 150 160
pF1KB5 G---FVRALAELHSQNTLP-------SVTSAAQPVNGAGMVAPAVASVAGG--SGSGGFS
: .: ::. ... .:: :: : :.::. :: : . .. : ..::..:
NP_001 GSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVS---MV-PNIPGIPGPPVNSSGSIS
170 180 190 200 210 220
170 180 190 200 210
pF1KB5 ASLHSEPP-VYANLSNFNPGALSS--GGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPV
: : : . :. .:: :: . :.:. :.:.: .:. .
NP_001 PSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQ---------SQILI
230 240 250 260 270
220 230 240 250 260 270
pF1KB5 QHPRLQALKEEPQTVPEMPGETPPLS-----PIDMESQERIKAERKRM--RNRIAASKCR
::: . .::. : .: :: . .: . .:: :.:. ::: :::.::
NP_001 QHPDAPS-PAQPQVSPAQP--TPSTGGRRRRTVDEDPDER----RQRFLERNRAAASRCR
280 290 300 310 320
280 290 300 310 320 330
pF1KB5 KRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQT
... .. ::.:.. : .:: .:.. ...::..:::::: .. : . : . :.
NP_001 QKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKD--CPVTALQKKTQ
330 340 350 360 370 380
pF1KB5 F
NP_001 GYLESPKESSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPI
390 400 410 420 430 440
>>XP_016874211 (OMIM: 606371) PREDICTED: cyclic AMP-depe (483 aa)
initn: 263 init1: 166 opt: 264 Z-score: 176.5 bits: 41.5 E(85289): 0.0043
Smith-Waterman score: 282; 30.4% identity (55.4% similar) in 260 aa overlap (90-327:168-405)
60 70 80 90 100 110
pF1KB5 LLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEG---FVR
: :.::. . ...: : : .:
XP_016 PKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSNRQMGSPTGSLPLVM
140 150 160 170 180 190
120 130 140 150 160
pF1KB5 ALAELHSQNTLP-------SVTSAAQPVNGAGMVAPAVASVAGG--SGSGGFSASLHSEP
::. ... .:: :: : :.::. :: : . .. : ..::..: : : :
XP_016 HLANGQTMPVLPGPPVQMPSVISLARPVS---MV-PNIPGIPGPPVNSSGSISPSGHPIP
200 210 220 230 240 250
170 180 190 200 210 220
pF1KB5 P-VYANLSNFNPGALSS--GGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQA
. :. .:: :: . :.:. :.:.:.: . .::: .
XP_016 SEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQ---------ILIQHPDAPS
260 270 280 290 300
230 240 250 260 270
pF1KB5 LKEEPQTVPEMPGETPPLS-----PIDMESQERIKAERKRM--RNRIAASKCRKRKLERI
.::. : .: :: . .: . .:: :.:. ::: :::.::... .
XP_016 -PAQPQVSPAQP--TPSTGGRRRRTVDEDPDER----RQRFLERNRAAASRCRQKRKLWV
310 320 330 340 350
280 290 300 310 320 330
pF1KB5 ARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
. ::.:.. : .:: .:.. ...::..:::::: .. : . : . :.
XP_016 SSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKD--CPVTALQKKTQGYLESPK
360 370 380 390 400 410
XP_016 ESSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMT
420 430 440 450 460 470
>>NP_006847 (OMIM: 606371) cyclic AMP-dependent transcri (483 aa)
initn: 263 init1: 166 opt: 264 Z-score: 176.5 bits: 41.5 E(85289): 0.0043
Smith-Waterman score: 282; 30.4% identity (55.4% similar) in 260 aa overlap (90-327:168-405)
60 70 80 90 100 110
pF1KB5 LLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEG---FVR
: :.::. . ...: : : .:
NP_006 PKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSNRQMGSPTGSLPLVM
140 150 160 170 180 190
120 130 140 150 160
pF1KB5 ALAELHSQNTLP-------SVTSAAQPVNGAGMVAPAVASVAGG--SGSGGFSASLHSEP
::. ... .:: :: : :.::. :: : . .. : ..::..: : : :
NP_006 HLANGQTMPVLPGPPVQMPSVISLARPVS---MV-PNIPGIPGPPVNSSGSISPSGHPIP
200 210 220 230 240 250
170 180 190 200 210 220
pF1KB5 P-VYANLSNFNPGALSS--GGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQA
. :. .:: :: . :.:. :.:.:.: . .::: .
NP_006 SEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQ---------ILIQHPDAPS
260 270 280 290 300
230 240 250 260 270
pF1KB5 LKEEPQTVPEMPGETPPLS-----PIDMESQERIKAERKRM--RNRIAASKCRKRKLERI
.::. : .: :: . .: . .:: :.:. ::: :::.::... .
NP_006 -PAQPQVSPAQP--TPSTGGRRRRTVDEDPDER----RQRFLERNRAAASRCRQKRKLWV
310 320 330 340 350
280 290 300 310 320 330
pF1KB5 ARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
. ::.:.. : .:: .:.. ...::..:::::: .. : . : . :.
NP_006 SSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKD--CPVTALQKKTQGYLESPK
360 370 380 390 400 410
NP_006 ESSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMT
420 430 440 450 460 470
>>XP_005268644 (OMIM: 606371) PREDICTED: cyclic AMP-depe (483 aa)
initn: 263 init1: 166 opt: 264 Z-score: 176.5 bits: 41.5 E(85289): 0.0043
Smith-Waterman score: 282; 30.4% identity (55.4% similar) in 260 aa overlap (90-327:168-405)
60 70 80 90 100 110
pF1KB5 LLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEG---FVR
: :.::. . ...: : : .:
XP_005 PKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSNRQMGSPTGSLPLVM
140 150 160 170 180 190
120 130 140 150 160
pF1KB5 ALAELHSQNTLP-------SVTSAAQPVNGAGMVAPAVASVAGG--SGSGGFSASLHSEP
::. ... .:: :: : :.::. :: : . .. : ..::..: : : :
XP_005 HLANGQTMPVLPGPPVQMPSVISLARPVS---MV-PNIPGIPGPPVNSSGSISPSGHPIP
200 210 220 230 240 250
170 180 190 200 210 220
pF1KB5 P-VYANLSNFNPGALSS--GGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQA
. :. .:: :: . :.:. :.:.:.: . .::: .
XP_005 SEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQ---------ILIQHPDAPS
260 270 280 290 300
230 240 250 260 270
pF1KB5 LKEEPQTVPEMPGETPPLS-----PIDMESQERIKAERKRM--RNRIAASKCRKRKLERI
.::. : .: :: . .: . .:: :.:. ::: :::.::... .
XP_005 -PAQPQVSPAQP--TPSTGGRRRRTVDEDPDER----RQRFLERNRAAASRCRQKRKLWV
310 320 330 340 350
280 290 300 310 320 330
pF1KB5 ARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
. ::.:.. : .:: .:.. ...::..:::::: .. : . : . :.
XP_005 SSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKD--CPVTALQKKTQGYLESPK
360 370 380 390 400 410
XP_005 ESSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMT
420 430 440 450 460 470
331 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:34:49 2016 done: Thu Nov 3 17:34:50 2016
Total Scan time: 9.740 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]