FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5557, 464 aa 1>>>pF1KB5557 464 - 464 aa - 464 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5919+/-0.000382; mu= 17.2294+/- 0.024 mean_var=100.5939+/-19.985, 0's: 0 Z-trim(115.3): 152 B-trim: 130 in 1/50 Lambda= 0.127876 statistics sampled from 25544 (25726) to 25544 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.302), width: 16 Scan time: 7.830 The best scores are: opt bits E(85289) NP_006298 (OMIM: 300187) sushi repeat-containing p ( 464) 3218 604.4 2e-172 NP_001164221 (OMIM: 300187) sushi repeat-containin ( 444) 2863 538.9 1e-152 XP_016885382 (OMIM: 300187) PREDICTED: sushi repea ( 419) 2829 532.6 7.6e-151 NP_001164223 (OMIM: 300187) sushi repeat-containin ( 379) 2565 483.9 3.2e-136 NP_001164222 (OMIM: 300187) sushi repeat-containin ( 405) 2043 387.6 3.3e-107 NP_055282 (OMIM: 300642,300643) sushi repeat-conta ( 465) 1542 295.2 2.4e-79 XP_005245497 (OMIM: 147050,173610) PREDICTED: P-se ( 768) 239 55.1 8.1e-07 XP_005245492 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 239 55.1 8.5e-07 NP_002996 (OMIM: 147050,173610) P-selectin precurs ( 830) 239 55.1 8.5e-07 XP_005245493 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 239 55.1 8.5e-07 XP_005245496 (OMIM: 147050,173610) PREDICTED: P-se ( 790) 235 54.3 1.4e-06 XP_005245495 (OMIM: 147050,173610) PREDICTED: P-se ( 790) 235 54.3 1.4e-06 NP_000646 (OMIM: 153240) L-selectin precursor [Hom ( 385) 217 50.7 8.2e-06 XP_011515117 (OMIM: 608399) PREDICTED: CUB and sus (2173) 216 51.2 3.2e-05 XP_016868501 (OMIM: 608399) PREDICTED: CUB and sus (3463) 216 51.4 4.5e-05 NP_443132 (OMIM: 608399) CUB and sushi domain-cont (3538) 216 51.4 4.6e-05 XP_011515118 (OMIM: 608399) PREDICTED: CUB and sus (3603) 216 51.5 4.6e-05 NP_937757 (OMIM: 608399) CUB and sushi domain-cont (3667) 216 51.5 4.7e-05 XP_016868497 (OMIM: 608399) PREDICTED: CUB and sus (3681) 216 51.5 4.7e-05 NP_783641 (OMIM: 605886) complement component rece ( 569) 193 46.5 0.00023 NP_000441 (OMIM: 131210,145500) E-selectin precurs ( 610) 191 46.1 0.00032 XP_016868500 (OMIM: 608399) PREDICTED: CUB and sus (3507) 200 48.5 0.00035 XP_016868499 (OMIM: 608399) PREDICTED: CUB and sus (3577) 200 48.5 0.00036 XP_016868498 (OMIM: 608399) PREDICTED: CUB and sus (3637) 200 48.5 0.00036 NP_937756 (OMIM: 608399) CUB and sushi domain-cont (3707) 200 48.5 0.00036 NP_001017364 (OMIM: 120831) C4b-binding protein be ( 251) 184 44.5 0.00041 NP_001017366 (OMIM: 120831) C4b-binding protein be ( 251) 184 44.5 0.00041 NP_000707 (OMIM: 120831) C4b-binding protein beta ( 252) 184 44.5 0.00041 XP_005273311 (OMIM: 120831) PREDICTED: C4b-binding ( 252) 184 44.5 0.00041 NP_001017367 (OMIM: 120831) C4b-binding protein be ( 252) 184 44.5 0.00041 NP_001017365 (OMIM: 120831) C4b-binding protein be ( 252) 184 44.5 0.00041 NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 193 47.2 0.00087 XP_005273312 (OMIM: 120831) PREDICTED: C4b-binding ( 227) 176 42.9 0.0011 XP_016856597 (OMIM: 126700,134370,235400,609814,61 ( 446) 179 43.8 0.0012 NP_001014975 (OMIM: 126700,134370,235400,609814,61 ( 449) 179 43.8 0.0012 NP_000565 (OMIM: 125240,613793) complement decay-a ( 381) 178 43.5 0.0012 NP_001287833 (OMIM: 125240,613793) complement deca ( 384) 178 43.5 0.0012 XP_016855956 (OMIM: 125240,613793) PREDICTED: comp ( 412) 178 43.6 0.0013 NP_001287832 (OMIM: 125240,613793) complement deca ( 439) 178 43.6 0.0013 NP_001108224 (OMIM: 125240,613793) complement deca ( 440) 178 43.6 0.0013 NP_001287831 (OMIM: 125240,613793) complement deca ( 444) 178 43.6 0.0013 NP_060452 (OMIM: 615827) sushi domain-containing p ( 490) 176 43.3 0.0018 XP_016857077 (OMIM: 615827) PREDICTED: sushi domai ( 490) 176 43.3 0.0018 XP_016857076 (OMIM: 615827) PREDICTED: sushi domai ( 490) 176 43.3 0.0018 XP_016857073 (OMIM: 615827) PREDICTED: sushi domai ( 562) 176 43.3 0.002 NP_000564 (OMIM: 120620,607486,611162) complement (2039) 183 45.1 0.0021 XP_006711229 (OMIM: 120620,607486,611162) PREDICTE (2459) 183 45.2 0.0024 NP_000642 (OMIM: 120620,607486,611162) complement (2489) 183 45.2 0.0024 XP_011507507 (OMIM: 120620,607486,611162) PREDICTE (2554) 183 45.2 0.0025 XP_011507586 (OMIM: 134580,613235) PREDICTED: coag ( 675) 172 42.7 0.0039 >>NP_006298 (OMIM: 300187) sushi repeat-containing prote (464 aa) initn: 3218 init1: 3218 opt: 3218 Z-score: 3216.4 bits: 604.4 E(85289): 2e-172 Smith-Waterman score: 3218; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464) 10 20 30 40 50 60 pF1KB5 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVD 370 380 390 400 410 420 430 440 450 460 pF1KB5 KHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT :::::::::::::::::::::::::::::::::::::::::::: NP_006 KHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT 430 440 450 460 >>NP_001164221 (OMIM: 300187) sushi repeat-containing pr (444 aa) initn: 2902 init1: 2863 opt: 2863 Z-score: 2862.7 bits: 538.9 E(85289): 1e-152 Smith-Waterman score: 3024; 95.7% identity (95.7% similar) in 464 aa overlap (1-464:1-444) 10 20 30 40 50 60 pF1KB5 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI :::::::::::::::::::::::::::::::: :::::::: NP_001 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFP--------------------DTPWCSPI 10 20 30 40 70 80 90 100 110 120 pF1KB5 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVD 350 360 370 380 390 400 430 440 450 460 pF1KB5 KHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT :::::::::::::::::::::::::::::::::::::::::::: NP_001 KHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT 410 420 430 440 >>XP_016885382 (OMIM: 300187) PREDICTED: sushi repeat-co (419 aa) initn: 3093 init1: 2827 opt: 2829 Z-score: 2829.1 bits: 532.6 E(85289): 7.6e-151 Smith-Waterman score: 2829; 97.1% identity (98.1% similar) in 417 aa overlap (1-417:1-417) 10 20 30 40 50 60 pF1KB5 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVD ::::::::::::::::::::::::::::::::::::::::::: .. : . .: XP_016 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLSFITLTKLEPWILVSE 370 380 390 400 410 430 440 450 460 pF1KB5 KHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT >>NP_001164223 (OMIM: 300187) sushi repeat-containing pr (379 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 2566.5 bits: 483.9 E(85289): 3.2e-136 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363) 10 20 30 40 50 60 pF1KB5 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVD ::: NP_001 MLQAVAANPTLLLQYGASG 370 >>NP_001164222 (OMIM: 300187) sushi repeat-containing pr (405 aa) initn: 2070 init1: 1943 opt: 2043 Z-score: 2045.7 bits: 387.6 E(85289): 3.3e-107 Smith-Waterman score: 2642; 87.1% identity (87.3% similar) in 464 aa overlap (1-464:1-405) 10 20 30 40 50 60 pF1KB5 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 KVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKH--- 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 PTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPP :::: NP_001 --------------------------------------------------------MEPP 120 190 200 210 220 230 240 pF1KB5 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYT 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB5 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSP 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB5 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLG 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB5 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVD 310 320 330 340 350 360 430 440 450 460 pF1KB5 KHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT :::::::::::::::::::::::::::::::::::::::::::: NP_001 KHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT 370 380 390 400 >>NP_055282 (OMIM: 300642,300643) sushi repeat-containin (465 aa) initn: 1747 init1: 1521 opt: 1542 Z-score: 1545.4 bits: 295.2 E(85289): 2.4e-79 Smith-Waterman score: 1542; 45.9% identity (73.1% similar) in 453 aa overlap (17-462:13-464) 10 20 30 40 50 pF1KB5 MGSPAHRPALLLLLPPLLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSH--PR-----YKD ::..: : :. . ::: : :. . :.. :. :. NP_055 MASQLTQRGALFLLFFLTPAVTPTW-YAGSGYYPDESYNEVYAEEVPQAPALDYRV 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 TPWCSPIKVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV :: .... :.. : .:.:: :...:::::.. :..:..: : . : ..::: . NP_055 PRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 ICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPAS :.: :: .: . ..: . :..:. ..:::.: :: :: :.:.:. ::.. ::: NP_055 YCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 CVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEG :::..::.:.:: .:..:::.:::.:: :. : .:.::: .: : :.: :::.:::: NP_055 CVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 DHKIQYTVYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGG .: :.::.:::: :...::: :::.:.:: :. :..::. :.: :::::::::. : :: NP_055 EHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 YELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNL :. ::.:.:::::. :::. : :: :..::.: .::.::::::::.::::.:.: : NP_055 YDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 LYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYS :..:..::::. :::::::.:..:::: : .::: . . . .:: . :. NP_055 YYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSANIIEELRQFQRLTRSY 360 370 380 390 400 410 420 430 440 450 460 pF1KB5 FSMVLVDKHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT :.:::.::.:.:..::. : : .:..:: . : ..:.. . :. . : NP_055 FNMVLIDKQGIDRDRYMEPVTPEEIFTFIDDYLLSNQELTQRREQRDICE 420 430 440 450 460 >>XP_005245497 (OMIM: 147050,173610) PREDICTED: P-select (768 aa) initn: 293 init1: 138 opt: 239 Z-score: 243.4 bits: 55.1 E(85289): 8.1e-07 Smith-Waterman score: 413; 29.6% identity (52.1% similar) in 284 aa overlap (49-319:441-701) 20 30 40 50 60 70 pF1KB5 LLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI-KVKYGDVYCRAPQGGYY :. . : :.:. . . : . : : :. XP_005 VCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIP-CTPLLSPQNGTMTCVQPLGS-- 420 430 440 450 460 80 90 100 110 120 130 pF1KB5 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG .. . :.. :..:: : : : : . ::.:. .:. .:: : : .:.. : : XP_005 -SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDT 470 480 490 500 510 520 140 150 160 170 180 190 pF1KB5 -AYFN--SRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC---VDMEPPRIKCPSVKER . :: : :.. :. :. :.: .: : . ::. : .: ... : ..::. XP_005 RGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPA---- 530 540 550 560 570 580 200 210 220 230 240 pF1KB5 IAEPNKLTVRVSWETPE-GRDTAD--GILTDVILKGLPPGSNFPEGDHKIQYTVYDRAEN .. :.. :. . : .:. : . : : : : : :.:. : XP_005 LTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG----QWTAVTPA-- 590 600 610 620 630 250 260 270 280 290 300 pF1KB5 KGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDN--YGATCEFSCIGGYELQGSPARVCQ : :. .:..:.. . :.::. : ::. : : :. : :.:: .:: XP_005 ---C------RAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQ 640 650 660 670 680 310 320 330 340 350 360 pF1KB5 SNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQA : :: : ::: : XP_005 ENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPL 690 700 710 720 730 740 >>XP_005245492 (OMIM: 147050,173610) PREDICTED: P-select (830 aa) initn: 443 init1: 138 opt: 239 Z-score: 243.0 bits: 55.1 E(85289): 8.5e-07 Smith-Waterman score: 413; 29.6% identity (52.1% similar) in 284 aa overlap (49-319:503-763) 20 30 40 50 60 70 pF1KB5 LLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI-KVKYGDVYCRAPQGGYY :. . : :.:. . . : . : : :. XP_005 VCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIP-CTPLLSPQNGTMTCVQPLGS-- 480 490 500 510 520 80 90 100 110 120 130 pF1KB5 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG .. . :.. :..:: : : : : . ::.:. .:. .:: : : .:.. : : XP_005 -SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDT 530 540 550 560 570 580 140 150 160 170 180 190 pF1KB5 -AYFN--SRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC---VDMEPPRIKCPSVKER . :: : :.. :. :. :.: .: : . ::. : .: ... : ..::. XP_005 RGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPA---- 590 600 610 620 630 640 200 210 220 230 240 pF1KB5 IAEPNKLTVRVSWETPE-GRDTAD--GILTDVILKGLPPGSNFPEGDHKIQYTVYDRAEN .. :.. :. . : .:. : . : : : : : :.:. : XP_005 LTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG----QWTAVTPA-- 650 660 670 680 690 250 260 270 280 290 300 pF1KB5 KGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDN--YGATCEFSCIGGYELQGSPARVCQ : :. .:..:.. . :.::. : ::. : : :. : :.:: .:: XP_005 ---C------RAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQ 700 710 720 730 740 310 320 330 340 350 360 pF1KB5 SNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQA : :: : ::: : XP_005 ENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPL 750 760 770 780 790 800 >>NP_002996 (OMIM: 147050,173610) P-selectin precursor [ (830 aa) initn: 443 init1: 138 opt: 239 Z-score: 243.0 bits: 55.1 E(85289): 8.5e-07 Smith-Waterman score: 413; 29.6% identity (52.1% similar) in 284 aa overlap (49-319:503-763) 20 30 40 50 60 70 pF1KB5 LLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI-KVKYGDVYCRAPQGGYY :. . : :.:. . . : . : : :. NP_002 VCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIP-CTPLLSPQNGTMTCVQPLGS-- 480 490 500 510 520 80 90 100 110 120 130 pF1KB5 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG .. . :.. :..:: : : : : . ::.:. .:. .:: : : .:.. : : NP_002 -SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDT 530 540 550 560 570 580 140 150 160 170 180 190 pF1KB5 -AYFN--SRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC---VDMEPPRIKCPSVKER . :: : :.. :. :. :.: .: : . ::. : .: ... : ..::. NP_002 RGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPA---- 590 600 610 620 630 640 200 210 220 230 240 pF1KB5 IAEPNKLTVRVSWETPE-GRDTAD--GILTDVILKGLPPGSNFPEGDHKIQYTVYDRAEN .. :.. :. . : .:. : . : : : : : :.:. : NP_002 LTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG----QWTAVTPA-- 650 660 670 680 690 250 260 270 280 290 300 pF1KB5 KGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDN--YGATCEFSCIGGYELQGSPARVCQ : :. .:..:.. . :.::. : ::. : : :. : :.:: .:: NP_002 ---C------RAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQ 700 710 720 730 740 310 320 330 340 350 360 pF1KB5 SNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQA : :: : ::: : NP_002 ENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPL 750 760 770 780 790 800 >>XP_005245493 (OMIM: 147050,173610) PREDICTED: P-select (830 aa) initn: 443 init1: 138 opt: 239 Z-score: 243.0 bits: 55.1 E(85289): 8.5e-07 Smith-Waterman score: 413; 29.6% identity (52.1% similar) in 284 aa overlap (49-319:503-763) 20 30 40 50 60 70 pF1KB5 LLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPI-KVKYGDVYCRAPQGGYY :. . : :.:. . . : . : : :. XP_005 VCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIP-CTPLLSPQNGTMTCVQPLGS-- 480 490 500 510 520 80 90 100 110 120 130 pF1KB5 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG .. . :.. :..:: : : : : . ::.:. .:. .:: : : .:.. : : XP_005 -SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDT 530 540 550 560 570 580 140 150 160 170 180 190 pF1KB5 -AYFN--SRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC---VDMEPPRIKCPSVKER . :: : :.. :. :. :.: .: : . ::. : .: ... : ..::. XP_005 RGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPA---- 590 600 610 620 630 640 200 210 220 230 240 pF1KB5 IAEPNKLTVRVSWETPE-GRDTAD--GILTDVILKGLPPGSNFPEGDHKIQYTVYDRAEN .. :.. :. . : .:. : . : : : : : :.:. : XP_005 LTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG----QWTAVTPA-- 650 660 670 680 690 250 260 270 280 290 300 pF1KB5 KGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDN--YGATCEFSCIGGYELQGSPARVCQ : :. .:..:.. . :.::. : ::. : : :. : :.:: .:: XP_005 ---C------RAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQ 700 710 720 730 740 310 320 330 340 350 360 pF1KB5 SNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQA : :: : ::: : XP_005 ENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPL 750 760 770 780 790 800 464 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:05:52 2016 done: Sat Nov 5 13:05:54 2016 Total Scan time: 7.830 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]