Result of FASTA (omim) for
pF1KB5571
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5571, 918 aa
1>>>pF1KB5571 918 - 918 aa - 918 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4554+/-0.000465; mu= 9.8168+/- 0.029
mean_var=133.2952+/-28.157, 0's: 0 Z-trim(113.3): 356 B-trim: 483 in 2/55
Lambda= 0.111088
statistics sampled from 22063 (22520) to 22063 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.264), width: 16
Scan time: 12.880
The best scores are: opt bits E(85289)
NP_002175 (OMIM: 600694) interleukin-6 receptor su ( 918) 6194 1005.4 0
XP_016864931 (OMIM: 600694) PREDICTED: interleukin ( 617) 4175 681.7 2.9e-195
XP_016864930 (OMIM: 600694) PREDICTED: interleukin ( 629) 4006 654.6 4.2e-187
NP_001177910 (OMIM: 600694) interleukin-6 receptor ( 857) 2913 479.6 2.9e-134
NP_786943 (OMIM: 600694) interleukin-6 receptor su ( 329) 2186 362.8 1.6e-99
XP_011541445 (OMIM: 609510,613955) PREDICTED: inte ( 662) 909 158.3 1.1e-37
NP_001229567 (OMIM: 609510,613955) interleukin-31 ( 662) 909 158.3 1.1e-37
NP_001229566 (OMIM: 609510,613955) interleukin-31 ( 681) 909 158.3 1.2e-37
XP_011541444 (OMIM: 609510,613955) PREDICTED: inte ( 732) 909 158.3 1.2e-37
NP_001229565 (OMIM: 609510,613955) interleukin-31 ( 745) 909 158.3 1.3e-37
NP_620586 (OMIM: 609510,613955) interleukin-31 rec ( 764) 909 158.4 1.3e-37
NP_001229568 (OMIM: 609510,613955) interleukin-31 ( 622) 774 136.7 3.5e-31
XP_011541446 (OMIM: 609510,613955) PREDICTED: inte ( 622) 774 136.7 3.5e-31
XP_011541447 (OMIM: 609510,613955) PREDICTED: inte ( 594) 759 134.2 1.8e-30
NP_001284499 (OMIM: 609510,613955) interleukin-31 ( 582) 730 129.6 4.4e-29
NP_758519 (OMIM: 138971,162830,617014) granulocyte ( 783) 701 125.0 1.4e-27
NP_000751 (OMIM: 138971,162830,617014) granulocyte ( 836) 701 125.0 1.5e-27
XP_005270550 (OMIM: 138971,162830,617014) PREDICTE ( 835) 698 124.6 2.1e-27
XP_016855859 (OMIM: 138971,162830,617014) PREDICTE ( 863) 678 121.4 2e-26
XP_011539050 (OMIM: 138971,162830,617014) PREDICTE ( 863) 678 121.4 2e-26
NP_724781 (OMIM: 138971,162830,617014) granulocyte ( 863) 678 121.4 2e-26
XP_011539051 (OMIM: 138971,162830,617014) PREDICTE ( 862) 675 120.9 2.8e-26
NP_001284501 (OMIM: 609510,613955) interleukin-31 ( 440) 595 107.9 1.1e-22
NP_001245145 (OMIM: 601642) interleukin-12 recepto ( 635) 587 106.7 3.8e-22
NP_001245143 (OMIM: 601642) interleukin-12 recepto ( 659) 587 106.7 3.9e-22
NP_001306162 (OMIM: 601642) interleukin-12 recepto ( 659) 587 106.7 3.9e-22
XP_016856692 (OMIM: 601642) PREDICTED: interleukin ( 659) 587 106.7 3.9e-22
XP_016856691 (OMIM: 601642) PREDICTED: interleukin ( 700) 587 106.7 4.1e-22
XP_005270882 (OMIM: 601642) PREDICTED: interleukin ( 862) 587 106.8 4.9e-22
NP_001550 (OMIM: 601642) interleukin-12 receptor s ( 862) 587 106.8 4.9e-22
XP_005270884 (OMIM: 601642) PREDICTED: interleukin ( 862) 587 106.8 4.9e-22
XP_005270885 (OMIM: 601642) PREDICTED: interleukin ( 862) 587 106.8 4.9e-22
XP_011539685 (OMIM: 601642) PREDICTED: interleukin ( 862) 587 106.8 4.9e-22
XP_011539052 (OMIM: 138971,162830,617014) PREDICTE ( 639) 572 104.3 2e-21
XP_011512344 (OMIM: 151443,601559) PREDICTED: leuk (1097) 562 102.8 9.5e-21
NP_001121143 (OMIM: 151443,601559) leukemia inhibi (1097) 562 102.8 9.5e-21
XP_011512342 (OMIM: 151443,601559) PREDICTED: leuk (1097) 562 102.8 9.5e-21
NP_002301 (OMIM: 151443,601559) leukemia inhibitor (1097) 562 102.8 9.5e-21
XP_016864952 (OMIM: 151443,601559) PREDICTED: leuk (1097) 562 102.8 9.5e-21
XP_016864951 (OMIM: 151443,601559) PREDICTED: leuk (1115) 562 102.8 9.7e-21
XP_011539686 (OMIM: 601642) PREDICTED: interleukin ( 809) 509 94.3 2.7e-18
XP_016856693 (OMIM: 601642) PREDICTED: interleukin ( 498) 498 92.4 6.1e-18
XP_006710680 (OMIM: 601642) PREDICTED: interleukin ( 776) 498 92.5 8.8e-18
NP_001245144 (OMIM: 601642) interleukin-12 recepto ( 776) 498 92.5 8.8e-18
XP_011526726 (OMIM: 272430,604237) PREDICTED: cyto ( 404) 453 85.1 7.6e-16
XP_011526725 (OMIM: 272430,604237) PREDICTED: cyto ( 419) 453 85.1 7.8e-16
NP_004741 (OMIM: 272430,604237) cytokine receptor- ( 422) 453 85.1 7.8e-16
XP_011526724 (OMIM: 272430,604237) PREDICTED: cyto ( 423) 453 85.1 7.9e-16
XP_011512463 (OMIM: 105250,601743) PREDICTED: onco ( 800) 403 77.3 3.4e-13
NP_001185618 (OMIM: 601007,614963) leptin receptor ( 896) 385 74.4 2.8e-12
>>NP_002175 (OMIM: 600694) interleukin-6 receptor subuni (918 aa)
initn: 6194 init1: 6194 opt: 6194 Z-score: 5372.8 bits: 1005.4 E(85289): 0
Smith-Waterman score: 6194; 100.0% identity (100.0% similar) in 918 aa overlap (1-918:1-918)
10 20 30 40 50 60
pF1KB5 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG
850 860 870 880 890 900
910
pF1KB5 MPKSYLPQTVRQGGYMPQ
::::::::::::::::::
NP_002 MPKSYLPQTVRQGGYMPQ
910
>>XP_016864931 (OMIM: 600694) PREDICTED: interleukin-6 r (617 aa)
initn: 4175 init1: 4175 opt: 4175 Z-score: 3626.6 bits: 681.7 E(85289): 2.9e-195
Smith-Waterman score: 4175; 100.0% identity (100.0% similar) in 617 aa overlap (302-918:1-617)
280 290 300 310 320 330
pF1KB5 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS
::::::::::::::::::::::::::::::
XP_016 MKEDGKGYWSDWSEEASGITYEDRPSKAPS
10 20 30
340 350 360 370 380 390
pF1KB5 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL
40 50 60 70 80 90
400 410 420 430 440 450
pF1KB5 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK
100 110 120 130 140 150
460 470 480 490 500 510
pF1KB5 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK
160 170 180 190 200 210
520 530 540 550 560 570
pF1KB5 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD
220 230 240 250 260 270
580 590 600 610 620 630
pF1KB5 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL
280 290 300 310 320 330
640 650 660 670 680 690
pF1KB5 TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDV
340 350 360 370 380 390
700 710 720 730 740 750
pF1KB5 SVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQ
400 410 420 430 440 450
760 770 780 790 800 810
pF1KB5 NTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPR
460 470 480 490 500 510
820 830 840 850 860 870
pF1KB5 QQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEV
520 530 540 550 560 570
880 890 900 910
pF1KB5 SAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ
580 590 600 610
>>XP_016864930 (OMIM: 600694) PREDICTED: interleukin-6 r (629 aa)
initn: 4001 init1: 4001 opt: 4006 Z-score: 3480.1 bits: 654.6 E(85289): 4.2e-187
Smith-Waterman score: 4006; 98.2% identity (98.2% similar) in 608 aa overlap (311-918:24-629)
290 300 310 320 330 340
pF1KB5 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH
: : :: :::::::::::::::
XP_016 MVRDTGVTGVKKQVGSPMKIHLISPWEAVDPGILV--GPSKAPSFWYKIDPSH
10 20 30 40 50
350 360 370 380 390 400
pF1KB5 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL
60 70 80 90 100 110
410 420 430 440 450 460
pF1KB5 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL
120 130 140 150 160 170
470 480 490 500 510 520
pF1KB5 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS
180 190 200 210 220 230
530 540 550 560 570 580
pF1KB5 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS
240 250 260 270 280 290
590 600 610 620 630 640
pF1KB5 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFC
300 310 320 330 340 350
650 660 670 680 690 700
pF1KB5 FNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEAND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEAND
360 370 380 390 400 410
710 720 730 740 750 760
pF1KB5 KKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYS
420 430 440 450 460 470
770 780 790 800 810 820
pF1KB5 TVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCS
480 490 500 510 520 530
830 840 850 860 870 880
pF1KB5 QHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPG
540 550 560 570 580 590
890 900 910
pF1KB5 TEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ
::::::::::::::::::::::::::::::::::::::
XP_016 TEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ
600 610 620
>>NP_001177910 (OMIM: 600694) interleukin-6 receptor sub (857 aa)
initn: 2912 init1: 2912 opt: 2913 Z-score: 2531.4 bits: 479.6 E(85289): 2.9e-134
Smith-Waterman score: 5619; 93.4% identity (93.4% similar) in 918 aa overlap (1-918:1-857)
10 20 30 40 50 60
pF1KB5 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT
::
NP_001 FQ----------------------------------------------------------
490 500 510 520 530 540
pF1KB5 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD
430 440 450 460 470
550 560 570 580 590 600
pF1KB5 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB5 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB5 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB5 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS
660 670 680 690 700 710
790 800 810 820 830 840
pF1KB5 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV
720 730 740 750 760 770
850 860 870 880 890 900
pF1KB5 NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG
780 790 800 810 820 830
910
pF1KB5 MPKSYLPQTVRQGGYMPQ
::::::::::::::::::
NP_001 MPKSYLPQTVRQGGYMPQ
840 850
>>NP_786943 (OMIM: 600694) interleukin-6 receptor subuni (329 aa)
initn: 2186 init1: 2186 opt: 2186 Z-score: 1907.9 bits: 362.8 E(85289): 1.6e-99
Smith-Waterman score: 2186; 100.0% identity (100.0% similar) in 324 aa overlap (1-324:1-324)
10 20 30 40 50 60
pF1KB5 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
::::::::::::::::::::::::
NP_786 CMKEDGKGYWSDWSEEASGITYEDNIASF
310 320
>>XP_011541445 (OMIM: 609510,613955) PREDICTED: interleu (662 aa)
initn: 736 init1: 507 opt: 909 Z-score: 797.3 bits: 158.3 E(85289): 1.1e-37
Smith-Waterman score: 909; 29.6% identity (61.7% similar) in 551 aa overlap (126-666:35-581)
100 110 120 130 140 150
pF1KB5 SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE
: ::.:.::. :.. : :. :.::
XP_011 PQPSCVNLGMMWTWALWMLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPGKETSY-
10 20 30 40 50 60
160 170 180 190 200 210
pF1KB5 TNFTLKSEWAT-HKFADCKAKRDTP---TSCTVDYSTVYFV-NIEVWVEAENALGKVTSD
:..:.: .: .: .: .. .: .::. . . : . :::::. : . :
XP_011 TQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKS-
70 80 90 100 110 120
220 230 240 250 260
pF1KB5 HINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDAST
:... . .. : .::. . : .. .... : .: . : :::....:: ....
XP_011 HMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTS
130 140 150 160 170 180
270 280 290 300 310 320
pF1KB5 WSQIP-PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS
: .. .. . ..... :.::::::. .:: ...: .:::::.: :.: :. :
XP_011 WMEVNFAKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESK-FWSDWSQEKMGMTEEEAPC
190 200 210 220 230 240
330 340 350 360 370 380
pF1KB5 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--
.: . :....: : :.:.:: . : : :.. .. . :.:.:
XP_011 GLE-LWRVLKPAEADGRRPVRLLWKKARGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQ
250 260 270 280 290 300
390 400 410 420 430 440
pF1KB5 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT
.: ..: .. . ... : .::: .:.: ::: . .. . . ..: ...: :.: .
XP_011 QLELHLGGESFWVSMISYNSLGKSPVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQS
310 320 330 340 350 360
450 460 470 480 490 500
pF1KB5 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG
.:. ...:: :. : .:.. . ... : . .: :: :.: :. : :
XP_011 SALDVNTWMIEWFPDVDSEPTTLSWESVSQATNWTIQQDKLKPFWCYNISVYPMLHDKVG
370 380 390 400 410 420
510 520 530 540 550 560
pF1KB5 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE
: ::.:: :.. ::.:: ......: . ... : ..: . ..:.: ::::::.. :.
XP_011 EPYSIQAYAKEGVPSEGPETKVENIGVKTVTITWKEIPKSERKGIICNYTIFYQAEGGKG
430 440 450 460 470 480
570 580 590 600 610 620
pF1KB5 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV
. .:.:: .: : :: : :.:.. : :. :: .: ..: : .:. :: :. .
XP_011 FSKTVNSSILQYGLESLKRKTSYIVQVMASTSAGGTNGTSINFKTLSFSVFEIILITSLI
490 500 510 520 530 540
630 640 650 660 670 680
pF1KB5 CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD
..:. .: : . ..: . . . ::.::.:..: :: :
XP_011 GGGLLILIILTVAYGLKKPNKLTHLCWPTVPNPAESSIATWHGDDFKDKLNLKESDDSVN
550 560 570 580 590 600
690 700 710 720 730 740
pF1KB5 GNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSD
XP_011 TEDRILKPCSTPSDKLVIDKLVVNFGNVLQEIFTDEARTGQENNLGGEKNGTRILSSCPT
610 620 630 640 650 660
>>NP_001229567 (OMIM: 609510,613955) interleukin-31 rece (662 aa)
initn: 736 init1: 507 opt: 909 Z-score: 797.3 bits: 158.3 E(85289): 1.1e-37
Smith-Waterman score: 909; 29.6% identity (61.7% similar) in 551 aa overlap (126-666:35-581)
100 110 120 130 140 150
pF1KB5 SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE
: ::.:.::. :.. : :. :.::
NP_001 PQPSCVNLGMMWTWALWMLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPGKETSY-
10 20 30 40 50 60
160 170 180 190 200 210
pF1KB5 TNFTLKSEWAT-HKFADCKAKRDTP---TSCTVDYSTVYFV-NIEVWVEAENALGKVTSD
:..:.: .: .: .: .. .: .::. . . : . :::::. : . :
NP_001 TQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKS-
70 80 90 100 110 120
220 230 240 250 260
pF1KB5 HINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDAST
:... . .. : .::. . : .. .... : .: . : :::....:: ....
NP_001 HMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTS
130 140 150 160 170 180
270 280 290 300 310 320
pF1KB5 WSQIP-PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS
: .. .. . ..... :.::::::. .:: ...: .:::::.: :.: :. :
NP_001 WMEVNFAKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESK-FWSDWSQEKMGMTEEEAPC
190 200 210 220 230 240
330 340 350 360 370 380
pF1KB5 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--
.: . :....: : :.:.:: . : : :.. .. . :.:.:
NP_001 GLE-LWRVLKPAEADGRRPVRLLWKKARGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQ
250 260 270 280 290 300
390 400 410 420 430 440
pF1KB5 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT
.: ..: .. . ... : .::: .:.: ::: . .. . . ..: ...: :.: .
NP_001 QLELHLGGESFWVSMISYNSLGKSPVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQS
310 320 330 340 350 360
450 460 470 480 490 500
pF1KB5 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG
.:. ...:: :. : .:.. . ... : . .: :: :.: :. : :
NP_001 SALDVNTWMIEWFPDVDSEPTTLSWESVSQATNWTIQQDKLKPFWCYNISVYPMLHDKVG
370 380 390 400 410 420
510 520 530 540 550 560
pF1KB5 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE
: ::.:: :.. ::.:: ......: . ... : ..: . ..:.: ::::::.. :.
NP_001 EPYSIQAYAKEGVPSEGPETKVENIGVKTVTITWKEIPKSERKGIICNYTIFYQAEGGKG
430 440 450 460 470 480
570 580 590 600 610 620
pF1KB5 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV
. .:.:: .: : :: : :.:.. : :. :: .: ..: : .:. :: :. .
NP_001 FSKTVNSSILQYGLESLKRKTSYIVQVMASTSAGGTNGTSINFKTLSFSVFEIILITSLI
490 500 510 520 530 540
630 640 650 660 670 680
pF1KB5 CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD
..:. .: : . ..: . . . ::.::.:..: :: :
NP_001 GGGLLILIILTVAYGLKKPNKLTHLCWPTVPNPAESSIATWHGDDFKDKLNLKESDDSVN
550 560 570 580 590 600
690 700 710 720 730 740
pF1KB5 GNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSD
NP_001 TEDRILKPCSTPSDKLVIDKLVVNFGNVLQEIFTDEARTGQENNLGGEKNGTRILSSCPT
610 620 630 640 650 660
>>NP_001229566 (OMIM: 609510,613955) interleukin-31 rece (681 aa)
initn: 736 init1: 507 opt: 909 Z-score: 797.1 bits: 158.3 E(85289): 1.2e-37
Smith-Waterman score: 909; 29.6% identity (61.7% similar) in 551 aa overlap (126-666:54-600)
100 110 120 130 140 150
pF1KB5 SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE
: ::.:.::. :.. : :. :.::
NP_001 PQPSCVNLGMMWTWALWMLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPGKETSY-
30 40 50 60 70 80
160 170 180 190 200 210
pF1KB5 TNFTLKSEWAT-HKFADCKAKRDTP---TSCTVDYSTVYFV-NIEVWVEAENALGKVTSD
:..:.: .: .: .: .. .: .::. . . : . :::::. : . :
NP_001 TQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKS-
90 100 110 120 130 140
220 230 240 250 260
pF1KB5 HINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDAST
:... . .. : .::. . : .. .... : .: . : :::....:: ....
NP_001 HMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTS
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB5 WSQIP-PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS
: .. .. . ..... :.::::::. .:: ...: .:::::.: :.: :. :
NP_001 WMEVNFAKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESK-FWSDWSQEKMGMTEEEAPC
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB5 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--
.: . :....: : :.:.:: . : : :.. .. . :.:.:
NP_001 GLE-LWRVLKPAEADGRRPVRLLWKKARGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQ
270 280 290 300 310
390 400 410 420 430 440
pF1KB5 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT
.: ..: .. . ... : .::: .:.: ::: . .. . . ..: ...: :.: .
NP_001 QLELHLGGESFWVSMISYNSLGKSPVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQS
320 330 340 350 360 370
450 460 470 480 490 500
pF1KB5 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG
.:. ...:: :. : .:.. . ... : . .: :: :.: :. : :
NP_001 SALDVNTWMIEWFPDVDSEPTTLSWESVSQATNWTIQQDKLKPFWCYNISVYPMLHDKVG
380 390 400 410 420 430
510 520 530 540 550 560
pF1KB5 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE
: ::.:: :.. ::.:: ......: . ... : ..: . ..:.: ::::::.. :.
NP_001 EPYSIQAYAKEGVPSEGPETKVENIGVKTVTITWKEIPKSERKGIICNYTIFYQAEGGKG
440 450 460 470 480 490
570 580 590 600 610 620
pF1KB5 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV
. .:.:: .: : :: : :.:.. : :. :: .: ..: : .:. :: :. .
NP_001 FSKTVNSSILQYGLESLKRKTSYIVQVMASTSAGGTNGTSINFKTLSFSVFEIILITSLI
500 510 520 530 540 550
630 640 650 660 670 680
pF1KB5 CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD
..:. .: : . ..: . . . ::.::.:..: :: :
NP_001 GGGLLILIILTVAYGLKKPNKLTHLCWPTVPNPAESSIATWHGDDFKDKLNLKESDDSVN
560 570 580 590 600 610
690 700 710 720 730 740
pF1KB5 GNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSD
NP_001 TEDRILKPCSTPSDKLVIDKLVVNFGNVLQEIFTDEARTGQENNLGGEKNGTRILSSCPT
620 630 640 650 660 670
>>XP_011541444 (OMIM: 609510,613955) PREDICTED: interleu (732 aa)
initn: 764 init1: 507 opt: 909 Z-score: 796.6 bits: 158.3 E(85289): 1.2e-37
Smith-Waterman score: 909; 29.6% identity (61.7% similar) in 551 aa overlap (126-666:22-568)
100 110 120 130 140 150
pF1KB5 SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE
: ::.:.::. :.. : :. :.::
XP_011 MMWTWALWMLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPGKETSY-
10 20 30 40 50
160 170 180 190 200 210
pF1KB5 TNFTLKSEWAT-HKFADCKAKRDTP---TSCTVDYSTVYFV-NIEVWVEAENALGKVTSD
:..:.: .: .: .: .. .: .::. . . : . :::::. : . :
XP_011 TQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKS-
60 70 80 90 100
220 230 240 250 260
pF1KB5 HINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDAST
:... . .. : .::. . : .. .... : .: . : :::....:: ....
XP_011 HMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTS
110 120 130 140 150 160
270 280 290 300 310 320
pF1KB5 WSQIP-PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS
: .. .. . ..... :.::::::. .:: ...: .:::::.: :.: :. :
XP_011 WMEVNFAKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESK-FWSDWSQEKMGMTEEEAPC
170 180 190 200 210 220
330 340 350 360 370 380
pF1KB5 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--
.: . :....: : :.:.:: . : : :.. .. . :.:.:
XP_011 GLE-LWRVLKPAEADGRRPVRLLWKKARGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQ
230 240 250 260 270 280
390 400 410 420 430 440
pF1KB5 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT
.: ..: .. . ... : .::: .:.: ::: . .. . . ..: ...: :.: .
XP_011 QLELHLGGESFWVSMISYNSLGKSPVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQS
290 300 310 320 330 340
450 460 470 480 490 500
pF1KB5 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG
.:. ...:: :. : .:.. . ... : . .: :: :.: :. : :
XP_011 SALDVNTWMIEWFPDVDSEPTTLSWESVSQATNWTIQQDKLKPFWCYNISVYPMLHDKVG
350 360 370 380 390 400
510 520 530 540 550 560
pF1KB5 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE
: ::.:: :.. ::.:: ......: . ... : ..: . ..:.: ::::::.. :.
XP_011 EPYSIQAYAKEGVPSEGPETKVENIGVKTVTITWKEIPKSERKGIICNYTIFYQAEGGKG
410 420 430 440 450 460
570 580 590 600 610 620
pF1KB5 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV
. .:.:: .: : :: : :.:.. : :. :: .: ..: : .:. :: :. .
XP_011 FSKTVNSSILQYGLESLKRKTSYIVQVMASTSAGGTNGTSINFKTLSFSVFEIILITSLI
470 480 490 500 510 520
630 640 650 660 670 680
pF1KB5 CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD
..:. .: : . ..: . . . ::.::.:..: :: :
XP_011 GGGLLILIILTVAYGLKKPNKLTHLCWPTVPNPAESSIATWHGDDFKDKLNLKESDDSVN
530 540 550 560 570 580
690 700 710 720 730 740
pF1KB5 GNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSD
XP_011 TEDRILKPCSTPSDKLVIDKLVVNFGNVLQEIFTDEARTGQENNLGGEKNGYVTCPFRPD
590 600 610 620 630 640
>>NP_001229565 (OMIM: 609510,613955) interleukin-31 rece (745 aa)
initn: 764 init1: 507 opt: 909 Z-score: 796.5 bits: 158.3 E(85289): 1.3e-37
Smith-Waterman score: 909; 29.6% identity (61.7% similar) in 551 aa overlap (126-666:35-581)
100 110 120 130 140 150
pF1KB5 SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE
: ::.:.::. :.. : :. :.::
NP_001 PQPSCVNLGMMWTWALWMLPSLCKFSLAALPAKPENISCVYYYRKNLTCTWSPGKETSY-
10 20 30 40 50 60
160 170 180 190 200 210
pF1KB5 TNFTLKSEWAT-HKFADCKAKRDTP---TSCTVDYSTVYFV-NIEVWVEAENALGKVTSD
:..:.: .: .: .: .. .: .::. . . : . :::::. : . :
NP_001 TQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKS-
70 80 90 100 110 120
220 230 240 250 260
pF1KB5 HINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDAST
:... . .. : .::. . : .. .... : .: . : :::....:: ....
NP_001 HMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTS
130 140 150 160 170 180
270 280 290 300 310 320
pF1KB5 WSQIP-PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS
: .. .. . ..... :.::::::. .:: ...: .:::::.: :.: :. :
NP_001 WMEVNFAKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESK-FWSDWSQEKMGMTEEEAPC
190 200 210 220 230 240
330 340 350 360 370 380
pF1KB5 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--
.: . :....: : :.:.:: . : : :.. .. . :.:.:
NP_001 GLE-LWRVLKPAEADGRRPVRLLWKKARGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQ
250 260 270 280 290 300
390 400 410 420 430 440
pF1KB5 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT
.: ..: .. . ... : .::: .:.: ::: . .. . . ..: ...: :.: .
NP_001 QLELHLGGESFWVSMISYNSLGKSPVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQS
310 320 330 340 350 360
450 460 470 480 490 500
pF1KB5 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG
.:. ...:: :. : .:.. . ... : . .: :: :.: :. : :
NP_001 SALDVNTWMIEWFPDVDSEPTTLSWESVSQATNWTIQQDKLKPFWCYNISVYPMLHDKVG
370 380 390 400 410 420
510 520 530 540 550 560
pF1KB5 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE
: ::.:: :.. ::.:: ......: . ... : ..: . ..:.: ::::::.. :.
NP_001 EPYSIQAYAKEGVPSEGPETKVENIGVKTVTITWKEIPKSERKGIICNYTIFYQAEGGKG
430 440 450 460 470 480
570 580 590 600 610 620
pF1KB5 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV
. .:.:: .: : :: : :.:.. : :. :: .: ..: : .:. :: :. .
NP_001 FSKTVNSSILQYGLESLKRKTSYIVQVMASTSAGGTNGTSINFKTLSFSVFEIILITSLI
490 500 510 520 530 540
630 640 650 660 670 680
pF1KB5 CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD
..:. .: : . ..: . . . ::.::.:..: :: :
NP_001 GGGLLILIILTVAYGLKKPNKLTHLCWPTVPNPAESSIATWHGDDFKDKLNLKESDDSVN
550 560 570 580 590 600
690 700 710 720 730 740
pF1KB5 GNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSD
NP_001 TEDRILKPCSTPSDKLVIDKLVVNFGNVLQEIFTDEARTGQENNLGGEKNGYVTCPFRPD
610 620 630 640 650 660
918 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:37:26 2016 done: Thu Nov 3 17:37:28 2016
Total Scan time: 12.880 Total Display time: 0.210
Function used was FASTA [36.3.4 Apr, 2011]