FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5585, 325 aa
1>>>pF1KB5585 325 - 325 aa - 325 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.7922+/-0.000706; mu= -27.5435+/- 0.041
mean_var=825.9302+/-195.146, 0's: 0 Z-trim(112.5): 130 B-trim: 2516 in 2/50
Lambda= 0.044628
statistics sampled from 21412 (21510) to 21412 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.252), width: 16
Scan time: 7.460
The best scores are: opt bits E(85289)
NP_001258670 (OMIM: 600505) casein kinase I isofor ( 325) 2173 156.1 9.5e-38
NP_001883 (OMIM: 600505) casein kinase I isoform a ( 337) 2165 155.6 1.4e-37
NP_689407 (OMIM: 600863) casein kinase I isoform e ( 416) 1575 117.7 4.3e-26
NP_001885 (OMIM: 600863) casein kinase I isoform e ( 416) 1575 117.7 4.3e-26
NP_620693 (OMIM: 600864,615224) casein kinase I is ( 409) 1573 117.5 4.7e-26
NP_001884 (OMIM: 600864,615224) casein kinase I is ( 415) 1573 117.6 4.7e-26
XP_005256394 (OMIM: 600864,615224) PREDICTED: case ( 427) 1573 117.6 4.8e-26
XP_005256393 (OMIM: 600864,615224) PREDICTED: case ( 450) 1573 117.6 4.9e-26
XP_016879688 (OMIM: 600864,615224) PREDICTED: case ( 393) 1334 102.1 2e-21
NP_001258671 (OMIM: 600505) casein kinase I isofor ( 276) 1165 91.1 3e-18
NP_001020276 (OMIM: 600505) casein kinase I isofor ( 365) 1165 91.2 3.5e-18
XP_005271953 (OMIM: 604253) PREDICTED: casein kina ( 416) 1127 88.8 2.1e-17
NP_001257501 (OMIM: 604253) casein kinase I isofor ( 424) 1127 88.9 2.1e-17
XP_016864558 (OMIM: 604253) PREDICTED: casein kina ( 424) 1127 88.9 2.1e-17
XP_005271952 (OMIM: 604253) PREDICTED: casein kina ( 424) 1127 88.9 2.1e-17
XP_005271948 (OMIM: 604253) PREDICTED: casein kina ( 456) 1127 88.9 2.2e-17
XP_016864559 (OMIM: 604253) PREDICTED: casein kina ( 415) 1116 88.1 3.4e-17
NP_001026982 (OMIM: 604253) casein kinase I isofor ( 423) 1116 88.1 3.4e-17
XP_005271951 (OMIM: 604253) PREDICTED: casein kina ( 447) 1116 88.2 3.5e-17
NP_004375 (OMIM: 604253) casein kinase I isoform g ( 447) 1116 88.2 3.5e-17
XP_005271949 (OMIM: 604253) PREDICTED: casein kina ( 455) 1116 88.2 3.6e-17
NP_001038188 (OMIM: 604253) casein kinase I isofor ( 455) 1116 88.2 3.6e-17
NP_001316535 (OMIM: 606274) casein kinase I isofor ( 422) 1112 87.9 4.1e-17
NP_071331 (OMIM: 606274) casein kinase I isoform g ( 422) 1112 87.9 4.1e-17
NP_001316536 (OMIM: 606274) casein kinase I isofor ( 438) 1112 87.9 4.2e-17
NP_001316534 (OMIM: 606274) casein kinase I isofor ( 475) 1112 88.0 4.4e-17
NP_001310 (OMIM: 602214) casein kinase I isoform g ( 415) 1099 87.0 7.2e-17
XP_005259557 (OMIM: 602214) PREDICTED: casein kina ( 440) 1099 87.1 7.5e-17
XP_016864556 (OMIM: 604253) PREDICTED: casein kina ( 441) 1049 83.9 7e-16
XP_016864553 (OMIM: 604253) PREDICTED: casein kina ( 449) 1049 83.9 7.1e-16
XP_016864552 (OMIM: 604253) PREDICTED: casein kina ( 473) 1049 83.9 7.3e-16
XP_016864547 (OMIM: 604253) PREDICTED: casein kina ( 481) 1049 83.9 7.4e-16
XP_016864548 (OMIM: 604253) PREDICTED: casein kina ( 481) 1049 83.9 7.4e-16
XP_016864549 (OMIM: 604253) PREDICTED: casein kina ( 481) 1049 83.9 7.4e-16
XP_016864546 (OMIM: 604253) PREDICTED: casein kina ( 481) 1049 83.9 7.4e-16
XP_016864557 (OMIM: 604253) PREDICTED: casein kina ( 440) 1038 83.1 1.1e-15
XP_016864555 (OMIM: 604253) PREDICTED: casein kina ( 448) 1038 83.2 1.2e-15
XP_016864554 (OMIM: 604253) PREDICTED: casein kina ( 448) 1038 83.2 1.2e-15
XP_016864551 (OMIM: 604253) PREDICTED: casein kina ( 480) 1038 83.2 1.2e-15
XP_016864550 (OMIM: 604253) PREDICTED: casein kina ( 480) 1038 83.2 1.2e-15
XP_016881787 (OMIM: 602214) PREDICTED: casein kina ( 367) 1020 81.9 2.3e-15
XP_005259558 (OMIM: 602214) PREDICTED: casein kina ( 392) 1020 81.9 2.4e-15
NP_001257502 (OMIM: 604253) casein kinase I isofor ( 348) 997 80.4 6.2e-15
XP_016881786 (OMIM: 602214) PREDICTED: casein kina ( 445) 933 76.4 1.2e-13
XP_005259555 (OMIM: 602214) PREDICTED: casein kina ( 445) 933 76.4 1.2e-13
XP_005259556 (OMIM: 602214) PREDICTED: casein kina ( 445) 933 76.4 1.2e-13
NP_001257503 (OMIM: 604253) casein kinase I isofor ( 311) 903 74.3 3.8e-13
NP_775771 (OMIM: 604432,611695) tau-tubulin kinase (1244) 573 53.8 2.2e-06
XP_006720466 (OMIM: 604432,611695) PREDICTED: tau- (1175) 452 46.0 0.00048
XP_005254230 (OMIM: 604432,611695) PREDICTED: tau- (1175) 452 46.0 0.00048
>>NP_001258670 (OMIM: 600505) casein kinase I isoform al (325 aa)
initn: 2173 init1: 2173 opt: 2173 Z-score: 798.7 bits: 156.1 E(85289): 9.5e-38
Smith-Waterman score: 2173; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KB5 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
250 260 270 280 290 300
310 320
pF1KB5 LKQKAAQQAASSSGQGQQAQTPTGF
:::::::::::::::::::::::::
NP_001 LKQKAAQQAASSSGQGQQAQTPTGF
310 320
>>NP_001883 (OMIM: 600505) casein kinase I isoform alpha (337 aa)
initn: 2165 init1: 2165 opt: 2165 Z-score: 795.7 bits: 155.6 E(85289): 1.4e-37
Smith-Waterman score: 2165; 100.0% identity (100.0% similar) in 324 aa overlap (1-324:1-324)
10 20 30 40 50 60
pF1KB5 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
250 260 270 280 290 300
310 320
pF1KB5 LKQKAAQQAASSSGQGQQAQTPTGF
::::::::::::::::::::::::
NP_001 LKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
310 320 330
>>NP_689407 (OMIM: 600863) casein kinase I isoform epsil (416 aa)
initn: 1572 init1: 1572 opt: 1575 Z-score: 589.4 bits: 117.7 E(85289): 4.3e-26
Smith-Waterman score: 1575; 75.5% identity (91.6% similar) in 298 aa overlap (10-307:2-299)
10 20 30 40 50 60
pF1KB5 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
:. ::.::.: :::::::::::::. ::..:::::.::: :..:::: :
NP_689 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.::..::::::: :.: : : ::::.::.:::::::::::::::.:..::::.:::::
NP_689 SKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
NP_689 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
NP_689 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::. :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_689 MSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320
pF1KB5 LKQKAAQQAASSSGQGQQAQTPTGF
:: ::.
NP_689 LKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTP
300 310 320 330 340 350
>>NP_001885 (OMIM: 600863) casein kinase I isoform epsil (416 aa)
initn: 1572 init1: 1572 opt: 1575 Z-score: 589.4 bits: 117.7 E(85289): 4.3e-26
Smith-Waterman score: 1575; 75.5% identity (91.6% similar) in 298 aa overlap (10-307:2-299)
10 20 30 40 50 60
pF1KB5 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
:. ::.::.: :::::::::::::. ::..:::::.::: :..:::: :
NP_001 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.::..::::::: :.: : : ::::.::.:::::::::::::::.:..::::.:::::
NP_001 SKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
NP_001 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
NP_001 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::. :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_001 MSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320
pF1KB5 LKQKAAQQAASSSGQGQQAQTPTGF
:: ::.
NP_001 LKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTP
300 310 320 330 340 350
>>NP_620693 (OMIM: 600864,615224) casein kinase I isofor (409 aa)
initn: 1568 init1: 1568 opt: 1573 Z-score: 588.8 bits: 117.5 E(85289): 4.7e-26
Smith-Waterman score: 1573; 75.0% identity (91.0% similar) in 300 aa overlap (10-309:2-301)
10 20 30 40 50 60
pF1KB5 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
:. ::..:.: :::::::::::::. .:. :::::.::: :..:::: :
NP_620 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.::..::::::: ::: : : ::::.::.:::::::::::::::.:..::::.:::::
NP_620 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
NP_620 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
NP_620 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_620 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320
pF1KB5 LKQKAAQQAASSSGQGQQAQTPTGF
:: :.. :
NP_620 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
300 310 320 330 340 350
>>NP_001884 (OMIM: 600864,615224) casein kinase I isofor (415 aa)
initn: 1568 init1: 1568 opt: 1573 Z-score: 588.7 bits: 117.6 E(85289): 4.7e-26
Smith-Waterman score: 1573; 75.0% identity (91.0% similar) in 300 aa overlap (10-309:2-301)
10 20 30 40 50 60
pF1KB5 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
:. ::..:.: :::::::::::::. .:. :::::.::: :..:::: :
NP_001 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.::..::::::: ::: : : ::::.::.:::::::::::::::.:..::::.:::::
NP_001 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
NP_001 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
NP_001 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_001 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320
pF1KB5 LKQKAAQQAASSSGQGQQAQTPTGF
:: :.. :
NP_001 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
300 310 320 330 340 350
>>XP_005256394 (OMIM: 600864,615224) PREDICTED: casein k (427 aa)
initn: 1568 init1: 1568 opt: 1573 Z-score: 588.6 bits: 117.6 E(85289): 4.8e-26
Smith-Waterman score: 1573; 75.0% identity (91.0% similar) in 300 aa overlap (10-309:2-301)
10 20 30 40 50 60
pF1KB5 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
:. ::..:.: :::::::::::::. .:. :::::.::: :..:::: :
XP_005 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.::..::::::: ::: : : ::::.::.:::::::::::::::.:..::::.:::::
XP_005 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
XP_005 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
XP_005 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
XP_005 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320
pF1KB5 LKQKAAQQAASSSGQGQQAQTPTGF
:: :.. :
XP_005 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
300 310 320 330 340 350
>>XP_005256393 (OMIM: 600864,615224) PREDICTED: casein k (450 aa)
initn: 1568 init1: 1568 opt: 1573 Z-score: 588.3 bits: 117.6 E(85289): 4.9e-26
Smith-Waterman score: 1573; 75.0% identity (91.0% similar) in 300 aa overlap (10-309:2-301)
10 20 30 40 50 60
pF1KB5 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
:. ::..:.: :::::::::::::. .:. :::::.::: :..:::: :
XP_005 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
::.::..::::::: ::: : : ::::.::.:::::::::::::::.:..::::.:::::
XP_005 SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
XP_005 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
XP_005 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
::::.::::::.:.::: :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
XP_005 MSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
240 250 260 270 280 290
310 320
pF1KB5 LKQKAAQQAASSSGQGQQAQTPTGF
:: :.. :
XP_005 LKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHT
300 310 320 330 340 350
>>XP_016879688 (OMIM: 600864,615224) PREDICTED: casein k (393 aa)
initn: 1329 init1: 1329 opt: 1334 Z-score: 505.8 bits: 102.1 E(85289): 2e-21
Smith-Waterman score: 1334; 77.0% identity (92.2% similar) in 244 aa overlap (66-309:1-244)
40 50 60 70 80 90
pF1KB5 NITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGP
..::::::: ::: : : ::::.::.::::
XP_016 MMQGGVGIPTIRWCGAEGDYNVMVMELLGP
10 20 30
100 110 120 130 140 150
pF1KB5 SLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFL
:::::::::::.:..::::.:::::::::::.:.:::::::.::::::::.:.. : ...
XP_016 SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYI
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 IDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFN
::::::::::: ::.:::::::.:::::::::::::.:::::::::::.:::::::::::
XP_016 IDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFN
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 RTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYM
::::::::::::.::::.:::::::::.::::::.:.::: :::.::.:::.. :::
XP_016 LGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYS
160 170 180 190 200 210
280 290 300 310 320
pF1KB5 YLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGF
::::::: ::. . .:::.:::.::: :.. :
XP_016 YLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLP
220 230 240 250 260 270
XP_016 STASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLT
280 290 300 310 320 330
>>NP_001258671 (OMIM: 600505) casein kinase I isoform al (276 aa)
initn: 1165 init1: 1165 opt: 1165 Z-score: 448.7 bits: 91.1 E(85289): 3e-18
Smith-Waterman score: 1524; 89.4% identity (89.4% similar) in 263 aa overlap (90-324:1-263)
60 70 80 90 100 110
pF1KB5 ESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQ
::::::::::::::::::::::::::::::
NP_001 MDLLGPSLEDLFNFCSRRFTMKTVLMLADQ
10 20 30
120 130 140 150
pF1KB5 MISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNK---------------------------
:::::::::::::::::::::::::::::::::
NP_001 MISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLN
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB5 -LFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB5 MYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEA
160 170 180 190 200 210
280 290 300 310 320
pF1KB5 PDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGF
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTK
220 230 240 250 260 270
NP_001 SNMKGF
325 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:39:56 2016 done: Thu Nov 3 17:39:57 2016
Total Scan time: 7.460 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]