FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5588, 725 aa 1>>>pF1KB5588 725 - 725 aa - 725 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7245+/-0.000393; mu= 19.0164+/- 0.025 mean_var=89.5242+/-18.260, 0's: 0 Z-trim(114.0): 56 B-trim: 466 in 1/53 Lambda= 0.135551 statistics sampled from 23488 (23544) to 23488 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.276), width: 16 Scan time: 6.990 The best scores are: opt bits E(85289) NP_037434 (OMIM: 606968) eukaryotic elongation fac ( 725) 4967 981.9 0 XP_016878682 (OMIM: 606968) PREDICTED: eukaryotic ( 725) 4961 980.8 0 XP_016878683 (OMIM: 606968) PREDICTED: eukaryotic ( 704) 3177 631.9 2.6e-180 XP_016864139 (OMIM: 607347) PREDICTED: alpha-prote (1037) 270 63.5 4.9e-09 XP_016864140 (OMIM: 607347) PREDICTED: alpha-prote (1037) 270 63.5 4.9e-09 XP_016864138 (OMIM: 607347) PREDICTED: alpha-prote (1043) 270 63.5 4.9e-09 NP_001240813 (OMIM: 607347) alpha-protein kinase 1 (1166) 270 63.6 5.3e-09 XP_016864136 (OMIM: 607347) PREDICTED: alpha-prote (1173) 270 63.6 5.3e-09 XP_016864137 (OMIM: 607347) PREDICTED: alpha-prote (1173) 270 63.6 5.3e-09 XP_016864135 (OMIM: 607347) PREDICTED: alpha-prote (1210) 270 63.6 5.5e-09 XP_016864134 (OMIM: 607347) PREDICTED: alpha-prote (1224) 270 63.6 5.5e-09 XP_006714389 (OMIM: 607347) PREDICTED: alpha-prote (1225) 270 63.6 5.5e-09 XP_016864133 (OMIM: 607347) PREDICTED: alpha-prote (1228) 270 63.6 5.5e-09 XP_016864132 (OMIM: 607347) PREDICTED: alpha-prote (1231) 270 63.6 5.5e-09 NP_001095876 (OMIM: 607347) alpha-protein kinase 1 (1244) 270 63.6 5.6e-09 NP_079420 (OMIM: 607347) alpha-protein kinase 1 is (1244) 270 63.6 5.6e-09 XP_005263302 (OMIM: 607347) PREDICTED: alpha-prote (1245) 270 63.6 5.6e-09 XP_005263303 (OMIM: 607347) PREDICTED: alpha-prote (1245) 270 63.6 5.6e-09 XP_016864131 (OMIM: 607347) PREDICTED: alpha-prote (1250) 270 63.6 5.6e-09 XP_016864126 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_016864125 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_016864128 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_016864127 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_016864130 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_016864124 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_016864129 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_016864123 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_016864122 (OMIM: 607347) PREDICTED: alpha-prote (1251) 270 63.6 5.6e-09 XP_011516553 (OMIM: 602014,607009) PREDICTED: tran (1779) 226 55.1 2.9e-06 XP_016869777 (OMIM: 602014,607009) PREDICTED: tran (1852) 226 55.1 3e-06 XP_016869776 (OMIM: 602014,607009) PREDICTED: tran (1901) 226 55.1 3e-06 XP_011516552 (OMIM: 602014,607009) PREDICTED: tran (1930) 226 55.1 3.1e-06 XP_011516551 (OMIM: 602014,607009) PREDICTED: tran (1944) 226 55.1 3.1e-06 XP_011516550 (OMIM: 602014,607009) PREDICTED: tran (1975) 226 55.1 3.1e-06 XP_011516549 (OMIM: 602014,607009) PREDICTED: tran (1979) 226 55.1 3.1e-06 XP_011516548 (OMIM: 602014,607009) PREDICTED: tran (1981) 226 55.1 3.1e-06 XP_011516547 (OMIM: 602014,607009) PREDICTED: tran (1991) 226 55.1 3.1e-06 NP_001170782 (OMIM: 602014,607009) transient recep (2017) 226 55.1 3.2e-06 NP_001170781 (OMIM: 602014,607009) transient recep (2017) 226 55.1 3.2e-06 XP_011516546 (OMIM: 602014,607009) PREDICTED: tran (2021) 226 55.1 3.2e-06 NP_060132 (OMIM: 602014,607009) transient receptor (2022) 226 55.1 3.2e-06 XP_016877844 (OMIM: 105500,605692) PREDICTED: tran (1826) 215 52.9 1.3e-05 XP_016877843 (OMIM: 105500,605692) PREDICTED: tran (1826) 215 52.9 1.3e-05 NP_001288141 (OMIM: 105500,605692) transient recep (1864) 215 53.0 1.3e-05 NP_060142 (OMIM: 105500,605692) transient receptor (1865) 215 53.0 1.3e-05 XP_016877842 (OMIM: 105500,605692) PREDICTED: tran (1873) 215 53.0 1.3e-05 XP_016877841 (OMIM: 105500,605692) PREDICTED: tran (1874) 215 53.0 1.3e-05 XP_005254543 (OMIM: 105500,605692) PREDICTED: tran (1885) 215 53.0 1.3e-05 XP_016877840 (OMIM: 105500,605692) PREDICTED: tran (1893) 215 53.0 1.3e-05 XP_016877839 (OMIM: 105500,605692) PREDICTED: tran (1894) 215 53.0 1.3e-05 >>NP_037434 (OMIM: 606968) eukaryotic elongation factor (725 aa) initn: 4967 init1: 4967 opt: 4967 Z-score: 5249.7 bits: 981.9 E(85289): 0 Smith-Waterman score: 4967; 100.0% identity (100.0% similar) in 725 aa overlap (1-725:1-725) 10 20 30 40 50 60 pF1KB5 MADEDLIFRLEGVDGGQSPRAGHDGDSDGDSDDEEGYFICPITDDPSSNQNVNSKVNKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MADEDLIFRLEGVDGGQSPRAGHDGDSDGDSDDEEGYFICPITDDPSSNQNVNSKVNKYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 SNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 TGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 YFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 YFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 SNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 GVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RVRTLSGSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 RVRTLSGSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 MASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 VCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 VCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 EKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 EKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 LLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 LLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 DEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAW 670 680 690 700 710 720 pF1KB5 AQMEE ::::: NP_037 AQMEE >>XP_016878682 (OMIM: 606968) PREDICTED: eukaryotic elon (725 aa) initn: 4961 init1: 4961 opt: 4961 Z-score: 5243.3 bits: 980.8 E(85289): 0 Smith-Waterman score: 4961; 99.9% identity (100.0% similar) in 725 aa overlap (1-725:1-725) 10 20 30 40 50 60 pF1KB5 MADEDLIFRLEGVDGGQSPRAGHDGDSDGDSDDEEGYFICPITDDPSSNQNVNSKVNKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADEDLIFRLEGVDGGQSPRAGHDGDSDGDSDDEEGYFICPITDDPSSNQNVNSKVNKYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 YFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RVRTLSGSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDN .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVRTLSGSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 MASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 VCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 EKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDY 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 LLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAW 670 680 690 700 710 720 pF1KB5 AQMEE ::::: XP_016 AQMEE >>XP_016878683 (OMIM: 606968) PREDICTED: eukaryotic elon (704 aa) initn: 4807 init1: 3177 opt: 3177 Z-score: 3358.0 bits: 631.9 E(85289): 2.6e-180 Smith-Waterman score: 4769; 97.0% identity (97.1% similar) in 725 aa overlap (1-725:1-704) 10 20 30 40 50 60 pF1KB5 MADEDLIFRLEGVDGGQSPRAGHDGDSDGDSDDEEGYFICPITDDPSSNQNVNSKVNKYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADEDLIFRLEGVDGGQSPRAGHDGDSDGDSDDEEGYFICPITDDPSSNQNVNSKVNKYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 YFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RVRTLSGSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDN .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVRTLSGSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 MASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGR ::::::::::::::::::::::::::::::::::::::: XP_016 MASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREH--------------------- 430 440 450 490 500 510 520 530 540 pF1KB5 VCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFC 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB5 EKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDY 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB5 LLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQ 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB5 DEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAW 640 650 660 670 680 690 pF1KB5 AQMEE ::::: XP_016 AQMEE 700 >>XP_016864139 (OMIM: 607347) PREDICTED: alpha-protein k (1037 aa) initn: 187 init1: 87 opt: 270 Z-score: 283.3 bits: 63.5 E(85289): 4.9e-09 Smith-Waterman score: 270; 29.9% identity (56.2% similar) in 224 aa overlap (116-323:809-1026) 90 100 110 120 130 140 pF1KB5 KHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRE .:. . : .:... ... . :. XP_016 VRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQ 780 790 800 810 820 830 150 160 170 180 190 200 pF1KB5 CFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNR----H :. . :: .. : ::.: : : .: ::. :: :. . :.:. . XP_016 --RNAFWVHHLHQEEILG--RYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQ 840 850 860 870 880 890 210 220 230 240 250 pF1KB5 KPPKQVDIMQMCIIE-LKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQ--AF . : :. . :. :.:. : . .: :: :...: ..:. :. . . : :. XP_016 NIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTE-YKATEYGLAY 900 910 920 930 940 950 260 270 280 290 300 310 pF1KB5 SHFTFERSGHQLIVVDIQGV------GDLY-TDPQIHTETGTDFGDGNLGVRGMALFFYS .::..: :.:. .:::.:: : .: ::::::. : :.: ::. :: . XP_016 GHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTT-NFGKRGIFYFFNN 960 970 980 990 1000 1010 320 330 340 350 360 pF1KB5 -HA-CNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPRVRTLSGSR :. ::.::. ..: XP_016 QHVECNEICHRLSLTRPSMEKPCKS 1020 1030 >>XP_016864140 (OMIM: 607347) PREDICTED: alpha-protein k (1037 aa) initn: 187 init1: 87 opt: 270 Z-score: 283.3 bits: 63.5 E(85289): 4.9e-09 Smith-Waterman score: 270; 29.9% identity (56.2% similar) in 224 aa overlap (116-323:809-1026) 90 100 110 120 130 140 pF1KB5 KHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRE .:. . : .:... ... . :. XP_016 VRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQ 780 790 800 810 820 830 150 160 170 180 190 200 pF1KB5 CFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNR----H :. . :: .. : ::.: : : .: ::. :: :. . :.:. . XP_016 --RNAFWVHHLHQEEILG--RYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQ 840 850 860 870 880 890 210 220 230 240 250 pF1KB5 KPPKQVDIMQMCIIE-LKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQ--AF . : :. . :. :.:. : . .: :: :...: ..:. :. . . : :. XP_016 NIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTE-YKATEYGLAY 900 910 920 930 940 950 260 270 280 290 300 310 pF1KB5 SHFTFERSGHQLIVVDIQGV------GDLY-TDPQIHTETGTDFGDGNLGVRGMALFFYS .::..: :.:. .:::.:: : .: ::::::. : :.: ::. :: . XP_016 GHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTT-NFGKRGIFYFFNN 960 970 980 990 1000 1010 320 330 340 350 360 pF1KB5 -HA-CNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPRVRTLSGSR :. ::.::. ..: XP_016 QHVECNEICHRLSLTRPSMEKPCKS 1020 1030 >>XP_016864138 (OMIM: 607347) PREDICTED: alpha-protein k (1043 aa) initn: 187 init1: 87 opt: 270 Z-score: 283.3 bits: 63.5 E(85289): 4.9e-09 Smith-Waterman score: 270; 29.9% identity (56.2% similar) in 224 aa overlap (116-323:815-1032) 90 100 110 120 130 140 pF1KB5 KHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRE .:. . : .:... ... . :. XP_016 VRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQ 790 800 810 820 830 840 150 160 170 180 190 200 pF1KB5 CFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNR----H :. . :: .. : ::.: : : .: ::. :: :. . :.:. . XP_016 --RNAFWVHHLHQEEILG--RYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQ 850 860 870 880 890 900 210 220 230 240 250 pF1KB5 KPPKQVDIMQMCIIE-LKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQ--AF . : :. . :. :.:. : . .: :: :...: ..:. :. . . : :. XP_016 NIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTE-YKATEYGLAY 910 920 930 940 950 260 270 280 290 300 310 pF1KB5 SHFTFERSGHQLIVVDIQGV------GDLY-TDPQIHTETGTDFGDGNLGVRGMALFFYS .::..: :.:. .:::.:: : .: ::::::. : :.: ::. :: . XP_016 GHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTT-NFGKRGIFYFFNN 960 970 980 990 1000 1010 320 330 340 350 360 pF1KB5 -HA-CNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPRVRTLSGSR :. ::.::. ..: XP_016 QHVECNEICHRLSLTRPSMEKPCKS 1020 1030 1040 >>NP_001240813 (OMIM: 607347) alpha-protein kinase 1 iso (1166 aa) initn: 151 init1: 87 opt: 270 Z-score: 282.6 bits: 63.6 E(85289): 5.3e-09 Smith-Waterman score: 270; 29.9% identity (56.2% similar) in 224 aa overlap (116-323:939-1156) 90 100 110 120 130 140 pF1KB5 KHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRE .:. . : .:... ... . :. NP_001 VRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQ 910 920 930 940 950 960 150 160 170 180 190 200 pF1KB5 CFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNR----H :. . :: .. : ::.: : : .: ::. :: :. . :.:. . NP_001 --RNAFWVHHLHQEEILG--RYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQ 970 980 990 1000 1010 1020 210 220 230 240 250 pF1KB5 KPPKQVDIMQMCIIE-LKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQ--AF . : :. . :. :.:. : . .: :: :...: ..:. :. . . : :. NP_001 NIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTE-YKATEYGLAY 1030 1040 1050 1060 1070 1080 260 270 280 290 300 310 pF1KB5 SHFTFERSGHQLIVVDIQGV------GDLY-TDPQIHTETGTDFGDGNLGVRGMALFFYS .::..: :.:. .:::.:: : .: ::::::. : :.: ::. :: . NP_001 GHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTT-NFGKRGIFYFFNN 1090 1100 1110 1120 1130 1140 320 330 340 350 360 pF1KB5 -HA-CNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPRVRTLSGSR :. ::.::. ..: NP_001 QHVECNEICHRLSLTRPSMEKPCT 1150 1160 >>XP_016864136 (OMIM: 607347) PREDICTED: alpha-protein k (1173 aa) initn: 151 init1: 87 opt: 270 Z-score: 282.5 bits: 63.6 E(85289): 5.3e-09 Smith-Waterman score: 270; 29.9% identity (56.2% similar) in 224 aa overlap (116-323:945-1162) 90 100 110 120 130 140 pF1KB5 KHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRE .:. . : .:... ... . :. XP_016 VRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQ 920 930 940 950 960 970 150 160 170 180 190 200 pF1KB5 CFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNR----H :. . :: .. : ::.: : : .: ::. :: :. . :.:. . XP_016 --RNAFWVHHLHQEEILG--RYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQ 980 990 1000 1010 1020 1030 210 220 230 240 250 pF1KB5 KPPKQVDIMQMCIIE-LKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQ--AF . : :. . :. :.:. : . .: :: :...: ..:. :. . . : :. XP_016 NIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTE-YKATEYGLAY 1040 1050 1060 1070 1080 260 270 280 290 300 310 pF1KB5 SHFTFERSGHQLIVVDIQGV------GDLY-TDPQIHTETGTDFGDGNLGVRGMALFFYS .::..: :.:. .:::.:: : .: ::::::. : :.: ::. :: . XP_016 GHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTT-NFGKRGIFYFFNN 1090 1100 1110 1120 1130 1140 320 330 340 350 360 pF1KB5 -HA-CNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPRVRTLSGSR :. ::.::. ..: XP_016 QHVECNEICHRLSLTRPSMEKPCKS 1150 1160 1170 >>XP_016864137 (OMIM: 607347) PREDICTED: alpha-protein k (1173 aa) initn: 151 init1: 87 opt: 270 Z-score: 282.5 bits: 63.6 E(85289): 5.3e-09 Smith-Waterman score: 270; 29.9% identity (56.2% similar) in 224 aa overlap (116-323:945-1162) 90 100 110 120 130 140 pF1KB5 KHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRE .:. . : .:... ... . :. XP_016 VRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQ 920 930 940 950 960 970 150 160 170 180 190 200 pF1KB5 CFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNR----H :. . :: .. : ::.: : : .: ::. :: :. . :.:. . XP_016 --RNAFWVHHLHQEEILG--RYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQ 980 990 1000 1010 1020 1030 210 220 230 240 250 pF1KB5 KPPKQVDIMQMCIIE-LKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQ--AF . : :. . :. :.:. : . .: :: :...: ..:. :. . . : :. XP_016 NIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTE-YKATEYGLAY 1040 1050 1060 1070 1080 260 270 280 290 300 310 pF1KB5 SHFTFERSGHQLIVVDIQGV------GDLY-TDPQIHTETGTDFGDGNLGVRGMALFFYS .::..: :.:. .:::.:: : .: ::::::. : :.: ::. :: . XP_016 GHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTT-NFGKRGIFYFFNN 1090 1100 1110 1120 1130 1140 320 330 340 350 360 pF1KB5 -HA-CNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPRVRTLSGSR :. ::.::. ..: XP_016 QHVECNEICHRLSLTRPSMEKPCKS 1150 1160 1170 >>XP_016864135 (OMIM: 607347) PREDICTED: alpha-protein k (1210 aa) initn: 151 init1: 87 opt: 270 Z-score: 282.4 bits: 63.6 E(85289): 5.5e-09 Smith-Waterman score: 270; 29.9% identity (56.2% similar) in 224 aa overlap (116-323:982-1199) 90 100 110 120 130 140 pF1KB5 KHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRE .:. . : .:... ... . :. XP_016 VRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQ 960 970 980 990 1000 1010 150 160 170 180 190 200 pF1KB5 CFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNR----H :. . :: .. : ::.: : : .: ::. :: :. . :.:. . XP_016 --RNAFWVHHLHQEEILG--RYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQ 1020 1030 1040 1050 1060 210 220 230 240 250 pF1KB5 KPPKQVDIMQMCIIE-LKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQ--AF . : :. . :. :.:. : . .: :: :...: ..:. :. . . : :. XP_016 NIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTE-YKATEYGLAY 1070 1080 1090 1100 1110 1120 260 270 280 290 300 310 pF1KB5 SHFTFERSGHQLIVVDIQGV------GDLY-TDPQIHTETGTDFGDGNLGVRGMALFFYS .::..: :.:. .:::.:: : .: ::::::. : :.: ::. :: . XP_016 GHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTT-NFGKRGIFYFFNN 1130 1140 1150 1160 1170 1180 320 330 340 350 360 pF1KB5 -HA-CNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPRVRTLSGSR :. ::.::. ..: XP_016 QHVECNEICHRLSLTRPSMEKPCKS 1190 1200 1210 725 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:05:14 2016 done: Sat Nov 5 00:05:15 2016 Total Scan time: 6.990 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]