Result of FASTA (omim) for
pF1KB5590
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5590, 349 aa
1>>>pF1KB5590 349 - 349 aa - 349 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8426+/-0.000392; mu= 15.3989+/- 0.024
mean_var=152.1168+/-28.600, 0's: 0 Z-trim(118.2): 107 B-trim: 120 in 1/53
Lambda= 0.103989
statistics sampled from 30836 (30964) to 30836 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.363), width: 16
Scan time: 7.320
The best scores are: opt bits E(85289)
NP_001892 (OMIM: 121009) connective tissue growth ( 349) 2579 398.7 1e-110
NP_002505 (OMIM: 164958) protein NOV homolog precu ( 357) 1372 217.6 3.3e-56
NP_003873 (OMIM: 603398) WNT1-inducible-signaling ( 367) 1205 192.6 1.2e-48
XP_011534522 (OMIM: 208230,603400) PREDICTED: WNT1 ( 354) 996 161.2 3.2e-39
NP_003871 (OMIM: 208230,603400) WNT1-inducible-sig ( 354) 996 161.2 3.2e-39
NP_937882 (OMIM: 208230,603400) WNT1-inducible-sig ( 372) 996 161.2 3.3e-39
NP_001310299 (OMIM: 603399) WNT1-inducible-signali ( 250) 793 130.5 3.8e-30
NP_003872 (OMIM: 603399) WNT1-inducible-signaling ( 250) 793 130.5 3.8e-30
NP_001545 (OMIM: 602369) protein CYR61 precursor [ ( 381) 662 111.1 4e-24
NP_543028 (OMIM: 603398) WNT1-inducible-signaling ( 280) 601 101.8 1.9e-21
XP_011534525 (OMIM: 208230,603400) PREDICTED: WNT1 ( 160) 553 94.3 2e-19
XP_011534524 (OMIM: 208230,603400) PREDICTED: WNT1 ( 158) 361 65.5 9.3e-11
NP_001191798 (OMIM: 603398) WNT1-inducible-signali ( 155) 353 64.2 2.1e-10
NP_001191799 (OMIM: 603398) WNT1-inducible-signali ( 122) 315 58.4 9.5e-09
XP_016883606 (OMIM: 603399) PREDICTED: WNT1-induci ( 162) 304 56.9 3.5e-08
NP_001310298 (OMIM: 603399) WNT1-inducible-signali ( 218) 302 56.8 5.2e-08
NP_001275643 (OMIM: 602319) protein kinase C-bindi ( 753) 223 45.6 0.00041
NP_963845 (OMIM: 602319) protein kinase C-binding ( 763) 223 45.6 0.00041
NP_006148 (OMIM: 602319) protein kinase C-binding ( 810) 223 45.7 0.00043
NP_001275642 (OMIM: 602319) protein kinase C-bindi ( 838) 223 45.7 0.00044
NP_955381 (OMIM: 609344) kielin/chordin-like prote ( 814) 212 44.0 0.0013
XP_016867683 (OMIM: 609344) PREDICTED: kielin/chor (1093) 212 44.2 0.0016
XP_016867682 (OMIM: 609344) PREDICTED: kielin/chor (1102) 212 44.2 0.0016
XP_016867679 (OMIM: 609344) PREDICTED: kielin/chor (1466) 212 44.4 0.0019
XP_016867678 (OMIM: 609344) PREDICTED: kielin/chor (1526) 212 44.4 0.002
XP_016867677 (OMIM: 609344) PREDICTED: kielin/chor (1555) 212 44.4 0.002
XP_016867675 (OMIM: 609344) PREDICTED: kielin/chor (1615) 212 44.4 0.002
XP_016867676 (OMIM: 609344) PREDICTED: kielin/chor (1615) 212 44.4 0.002
XP_016867674 (OMIM: 609344) PREDICTED: kielin/chor (1628) 212 44.4 0.0021
XP_016867673 (OMIM: 609344) PREDICTED: kielin/chor (1633) 212 44.4 0.0021
NP_001129386 (OMIM: 609344) kielin/chordin-like pr (1503) 208 43.8 0.003
XP_016859749 (OMIM: 606189) PREDICTED: cysteine-ri ( 955) 202 42.6 0.0042
XP_011507814 (OMIM: 610278) PREDICTED: platelet en ( 868) 200 42.3 0.0049
XP_016856729 (OMIM: 610278) PREDICTED: platelet en ( 909) 200 42.3 0.005
XP_016856731 (OMIM: 610278) PREDICTED: platelet en ( 909) 200 42.3 0.005
XP_016856730 (OMIM: 610278) PREDICTED: platelet en ( 909) 200 42.3 0.005
XP_016856727 (OMIM: 610278) PREDICTED: platelet en ( 973) 200 42.3 0.0052
XP_016856726 (OMIM: 610278) PREDICTED: platelet en ( 973) 200 42.3 0.0052
XP_016856728 (OMIM: 610278) PREDICTED: platelet en ( 973) 200 42.3 0.0052
XP_011507813 (OMIM: 610278) PREDICTED: platelet en (1002) 200 42.3 0.0053
NP_001073940 (OMIM: 610278) platelet endothelial a (1037) 200 42.4 0.0054
XP_016856725 (OMIM: 610278) PREDICTED: platelet en (1037) 200 42.4 0.0054
XP_011507812 (OMIM: 610278) PREDICTED: platelet en (1037) 200 42.4 0.0054
XP_005245198 (OMIM: 610278) PREDICTED: platelet en (1037) 200 42.4 0.0054
XP_016856724 (OMIM: 610278) PREDICTED: platelet en (1081) 200 42.4 0.0056
XP_016856723 (OMIM: 610278) PREDICTED: platelet en (1125) 200 42.4 0.0057
NP_001138581 (OMIM: 602320) protein kinase C-bindi ( 815) 198 41.9 0.0058
NP_006150 (OMIM: 602320) protein kinase C-binding ( 816) 198 41.9 0.0058
XP_005268962 (OMIM: 602320) PREDICTED: protein kin ( 816) 198 41.9 0.0058
XP_011536698 (OMIM: 602320) PREDICTED: protein kin ( 816) 198 41.9 0.0058
>>NP_001892 (OMIM: 121009) connective tissue growth fact (349 aa)
initn: 2579 init1: 2579 opt: 2579 Z-score: 2108.7 bits: 398.7 E(85289): 1e-110
Smith-Waterman score: 2579; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KB5 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 AYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTT
250 260 270 280 290 300
310 320 330 340
pF1KB5 LPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
310 320 330 340
>>NP_002505 (OMIM: 164958) protein NOV homolog precursor (357 aa)
initn: 1367 init1: 919 opt: 1372 Z-score: 1130.0 bits: 217.6 E(85289): 3.3e-56
Smith-Waterman score: 1372; 52.1% identity (74.9% similar) in 338 aa overlap (15-348:21-357)
10 20 30 40 50
pF1KB5 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPC--RCPDEPAPRCPAGVSLVLD
.:: : .. :. : : : ::: : : : :: :::
NP_002 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATP-PTCAPGVRAVLD
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 GCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRS
::.:: :::.: :: :.. .::: .::.:: .. . . :.::: .: :.: :..:::
NP_002 GCSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 GESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQ
::.:: :::.:::: :: .::.: :..:: :: :.:: ::.:..::.:::.:.: ...
NP_002 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEED
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 TVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEK
.. : .::::: : :.: . . .::. :::::.::::.::::.:::::: : .:.. :
NP_002 SLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 QSRLCMVRPCEADLEENI-KKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGR
:.::::::::: . :. ::::::.:: : : :......:::..::. .:::::.:::
NP_002 QTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGR
240 250 260 270 280 290
300 310 320 330 340
pF1KB5 CCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIF-ESLYYRKMYGDMA
::::: : :. .::.: :...:: .: : ::.:: ::: .:. : . : . : :
NP_002 CCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
300 310 320 330 340 350
>>NP_003873 (OMIM: 603398) WNT1-inducible-signaling path (367 aa)
initn: 1102 init1: 543 opt: 1205 Z-score: 994.4 bits: 192.6 E(85289): 1.2e-48
Smith-Waterman score: 1205; 45.9% identity (70.5% similar) in 353 aa overlap (2-349:23-366)
10 20 30
pF1KB5 MTAASMGPVRVAFVV--LLALCSRPAVGQNCSGPCRCPD
:: : .:. . :. : ::: : :. ::.::
NP_003 MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRP---QFCKWPCECPP
10 20 30 40 50
40 50 60 70 80 90
pF1KB5 EPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANR-KIGVCT
: :::: ::::. ::: ::..::.:::. ::: ::::.::.::... : ::::.
NP_003 SP-PRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCA
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB5 AKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKL
:. :.. :. : .:.::: .:::.:::.:::::: ::: . :: : :: ::::..
NP_003 QVVGVGCVLDGVRYNNGQSFQPNCKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSI
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 PGKCCEEWVC-DEPKDQTVVGPA-LAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCG
::.:::.::: :. : ..: .:. :. : . : ::.. :. :: :: .::
NP_003 PGHCCEQWVCEDDAKRPRKTAPRDTGAF---DAVGEVEAWHR-NCIAYTSPWSPCSTSCG
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 MGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCT
.:.:::..: ::.: :..:::: .:::..:.. :: ::::. . . ..: :.::
NP_003 LGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCI
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 SMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDND
: ..:. :.:::: :.::: :... :. : :.:::: .......:..: :. .: . ::
NP_003 STRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPND
300 310 320 330 340 350
340
pF1KB5 IFESLYYRKMYGDMA
:: .: ....:
NP_003 IFADLESYPDFSEIAN
360
>>XP_011534522 (OMIM: 208230,603400) PREDICTED: WNT1-ind (354 aa)
initn: 973 init1: 309 opt: 996 Z-score: 825.2 bits: 161.2 E(85289): 3.2e-39
Smith-Waterman score: 996; 41.7% identity (68.5% similar) in 321 aa overlap (23-339:42-351)
10 20 30 40 50
pF1KB5 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLD
: : : ::.::.. :::: ::::: :
XP_011 AGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPCKCPQQK-PRCPPGVSLVRD
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB5 GCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANR-KIGVCTAKDGAPCIFGGTVYR
:::::..:::: ::.:.: : :::::::.::.. : . :::. .. : :. . :.
XP_011 GCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCEFNQVHYH
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB5 SGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCD-EPK
.:. :: . ..: :..::.:: :: . .: . : . :: .. :. ::
XP_011 NGQVFQPNPLFSCLCVSGAIGCTPL--FIPKLAGSHCSGAK----GGKKSDQSNCSLEPL
140 150 160 170 180
180 190 200 210 220 230
pF1KB5 DQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRL
: . ..:. .. : . . .::::.:.:. ::.:::::::.::::.:..:..
XP_011 LQQLS----TSYKTMPAYRNLPLIWKKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEM
190 200 210 220 230 240
240 250 260 270 280
pF1KB5 EKQSRLCMVRPCEADLEENIK--KGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCT
.:..:::...::.... ..:: ::: : : ..:: :: .:::.: ..:. :::.:
XP_011 RKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 DGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDM
: ::: :... . ..: ::. .: .:..: .:.:. :: .::: :
XP_011 DKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIFSELKIL
310 320 330 340 350
pF1KB5 A
>>NP_003871 (OMIM: 208230,603400) WNT1-inducible-signali (354 aa)
initn: 973 init1: 309 opt: 996 Z-score: 825.2 bits: 161.2 E(85289): 3.2e-39
Smith-Waterman score: 996; 41.7% identity (68.5% similar) in 321 aa overlap (23-339:42-351)
10 20 30 40 50
pF1KB5 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLD
: : : ::.::.. :::: ::::: :
NP_003 AGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPCKCPQQK-PRCPPGVSLVRD
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB5 GCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANR-KIGVCTAKDGAPCIFGGTVYR
:::::..:::: ::.:.: : :::::::.::.. : . :::. .. : :. . :.
NP_003 GCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCEFNQVHYH
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB5 SGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCD-EPK
.:. :: . ..: :..::.:: :: . .: . : . :: .. :. ::
NP_003 NGQVFQPNPLFSCLCVSGAIGCTPL--FIPKLAGSHCSGAK----GGKKSDQSNCSLEPL
140 150 160 170 180
180 190 200 210 220 230
pF1KB5 DQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRL
: . ..:. .. : . . .::::.:.:. ::.:::::::.::::.:..:..
NP_003 LQQLS----TSYKTMPAYRNLPLIWKKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEM
190 200 210 220 230 240
240 250 260 270 280
pF1KB5 EKQSRLCMVRPCEADLEENIK--KGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCT
.:..:::...::.... ..:: ::: : : ..:: :: .:::.: ..:. :::.:
NP_003 RKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB5 DGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDM
: ::: :... . ..: ::. .: .:..: .:.:. :: .::: :
NP_003 DKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIFSELKIL
310 320 330 340 350
pF1KB5 A
>>NP_937882 (OMIM: 208230,603400) WNT1-inducible-signali (372 aa)
initn: 973 init1: 309 opt: 996 Z-score: 824.9 bits: 161.2 E(85289): 3.3e-39
Smith-Waterman score: 996; 41.7% identity (68.5% similar) in 321 aa overlap (23-339:60-369)
10 20 30 40 50
pF1KB5 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLD
: : : ::.::.. :::: ::::: :
NP_937 AGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPCKCPQQK-PRCPPGVSLVRD
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB5 GCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANR-KIGVCTAKDGAPCIFGGTVYR
:::::..:::: ::.:.: : :::::::.::.. : . :::. .. : :. . :.
NP_937 GCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCEFNQVHYH
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB5 SGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCD-EPK
.:. :: . ..: :..::.:: :: . .: . : . :: .. :. ::
NP_937 NGQVFQPNPLFSCLCVSGAIGCTPL--FIPKLAGSHCSGAK----GGKKSDQSNCSLEPL
150 160 170 180 190 200
180 190 200 210 220 230
pF1KB5 DQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRL
: . ..:. .. : . . .::::.:.:. ::.:::::::.::::.:..:..
NP_937 LQQLS----TSYKTMPAYRNLPLIWKKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEM
210 220 230 240 250
240 250 260 270 280
pF1KB5 EKQSRLCMVRPCEADLEENIK--KGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCT
.:..:::...::.... ..:: ::: : : ..:: :: .:::.: ..:. :::.:
NP_937 RKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICL
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB5 DGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDM
: ::: :... . ..: ::. .: .:..: .:.:. :: .::: :
NP_937 DKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIFSELKIL
320 330 340 350 360 370
pF1KB5 A
>>NP_001310299 (OMIM: 603399) WNT1-inducible-signaling p (250 aa)
initn: 526 init1: 343 opt: 793 Z-score: 662.2 bits: 130.5 E(85289): 3.8e-30
Smith-Waterman score: 793; 45.7% identity (64.2% similar) in 243 aa overlap (7-242:3-237)
10 20 30 40 50
pF1KB5 MTAASMGPVRVAFVVLLALCSRPAV-GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRV
: .. .... :: : : : :: :: : :::: :: :::::::::::
NP_001 MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCP-WPPPRCPLGVPLVLDGCGCCRV
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 CAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCT-AKDGAPCIFGGTVYRSGESFQS
::..::: : . :: .:: :. :. . . ..: :.: . : .: .:: ::.::
NP_001 CARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDE-----PKDQT
:. .: : ::. :.:::: :::::: ::: ::::.. :::: :::: . .
NP_001 HCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 VVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQ
. :: ... : ... : . : .: :. :: :::.:..:::.:.: :::: :
NP_001 AQGPQFSG--LVSSLPPG-----VPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQ
180 190 200 210 220
240 250 260 270 280 290
pF1KB5 SRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCC
:::. :::
NP_001 RRLCLSRPCPPSRGRSPQNSAF
230 240 250
>>NP_003872 (OMIM: 603399) WNT1-inducible-signaling path (250 aa)
initn: 526 init1: 343 opt: 793 Z-score: 662.2 bits: 130.5 E(85289): 3.8e-30
Smith-Waterman score: 793; 45.7% identity (64.2% similar) in 243 aa overlap (7-242:3-237)
10 20 30 40 50
pF1KB5 MTAASMGPVRVAFVVLLALCSRPAV-GQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRV
: .. .... :: : : : :: :: : :::: :: :::::::::::
NP_003 MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCP-WPPPRCPLGVPLVLDGCGCCRV
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 CAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCT-AKDGAPCIFGGTVYRSGESFQS
::..::: : . :: .:: :. :. . . ..: :.: . : .: .:: ::.::
NP_003 CARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 SCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDE-----PKDQT
:. .: : ::. :.:::: :::::: ::: ::::.. :::: :::: . .
NP_003 HCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 VVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQ
. :: ... : ... : . : .: :. :: :::.:..:::.:.: :::: :
NP_003 AQGPQFSG--LVSSLPPG-----VPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQ
180 190 200 210 220
240 250 260 270 280 290
pF1KB5 SRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCC
:::. :::
NP_003 RRLCLSRPCPPSRGRSPQNSAF
230 240 250
>>NP_001545 (OMIM: 602369) protein CYR61 precursor [Homo (381 aa)
initn: 1198 init1: 611 opt: 662 Z-score: 554.0 bits: 111.1 E(85289): 4e-24
Smith-Waterman score: 1258; 47.3% identity (70.2% similar) in 372 aa overlap (11-348:9-376)
10 20 30 40 50 60
pF1KB5 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC
.:.:: : .: :.. .: . :.:: : ::.: ::.:: ::::::.::
NP_001 MSSRIARALALVVTLLHLTRLALS-TCPAACHCPLE-APKCAPGVGLVRDGCGCCKVC
10 20 30 40 50
70 80 90 100 110
pF1KB5 AKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAK-DGAPCIFGGTVYRSGESFQSS
::::.: :.. .::: ::: :.::. .. :.: :. .: :: ... .:..::::: .
NP_001 AKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 CKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDE-----P-KDQT
::.::::.::::::.::: ... ::. :: :: ::. :.::::::::: : .::
NP_001 CKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQD
120 130 140 150 160 170
180 190 200
pF1KB5 -VVGPALA--AYRLEDT-------------------FGPDPTMIRA-----NCLVQTTEW
..: :. : ..: : :: .: .. .:.:::: :
NP_001 GLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSW
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB5 SACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPI
: :::::: :::::::::: ::: :..:.: :::: . ..:::::: .: : .:.
NP_001 SQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPV
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB5 KFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACH
.: .:: :.: :: :.:: :.:::::::. : :. ..:.: :::...::.:.:..: :.
NP_001 RFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCN
300 310 320 330 340 350
330 340
pF1KB5 YNCPGDNDIFESLYYRKMYGDMA
:::: :. .. . ....:.
NP_001 YNCPHANEA--AFPFYRLFNDIHKFRD
360 370 380
>>NP_543028 (OMIM: 603398) WNT1-inducible-signaling path (280 aa)
initn: 843 init1: 543 opt: 601 Z-score: 506.0 bits: 101.8 E(85289): 1.9e-21
Smith-Waterman score: 718; 34.5% identity (53.8% similar) in 351 aa overlap (2-349:23-279)
10 20 30
pF1KB5 MTAASMGPVRVAFVV--LLALCSRPAVGQNCSGPCRCPD
:: : .:. . :. : ::: : :. ::.::
NP_543 MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRP---QFCKWPCECPP
10 20 30 40 50
40 50 60 70 80 90
pF1KB5 EPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANR-KIGVCT
: :::: ::::. ::: ::..::.:::. ::: ::::.::.::... : ::::.
NP_543 SP-PRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCA
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB5 AKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKL
::: .
NP_543 H--------------------------------AVGEV----------------------
120
160 170 180 190 200 210
pF1KB5 PGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMG
: : .: ::.. :. :: :: .::.:
NP_543 -----EAW-----------------HR--------------NCIAYTSPWSPCSTSCGLG
130 140
220 230 240 250 260 270
pF1KB5 ISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSM
.:::..: ::.: :..:::: .:::..:.. :: ::::. . . ..: :.:: :
NP_543 VSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCIST
150 160 170 180 190 200
280 290 300 310 320 330
pF1KB5 KTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIF
..:. :.:::: :.::: :... :. : :.:::: .......:..: :. .: . ::::
NP_543 RSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIF
210 220 230 240 250 260
340
pF1KB5 ESLYYRKMYGDMA
.: ....:
NP_543 ADLESYPDFSEIAN
270 280
349 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:58:00 2016 done: Fri Nov 4 03:58:01 2016
Total Scan time: 7.320 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]