FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5603, 466 aa 1>>>pF1KB5603 466 - 466 aa - 466 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0195+/-0.00092; mu= 9.1517+/- 0.056 mean_var=97.7978+/-19.226, 0's: 0 Z-trim(108.0): 20 B-trim: 50 in 1/48 Lambda= 0.129691 statistics sampled from 9900 (9913) to 9900 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.305), width: 16 Scan time: 3.150 The best scores are: opt bits E(32554) CCDS10110.1 CTDSPL2 gene_id:51496|Hs108|chr15 ( 466) 3051 581.4 7e-166 CCDS33735.1 CTDSPL gene_id:10217|Hs108|chr3 ( 265) 538 111.1 1.5e-24 CCDS33734.1 CTDSPL gene_id:10217|Hs108|chr3 ( 276) 516 107.0 2.6e-23 CCDS56166.1 CTDSP1 gene_id:58190|Hs108|chr2 ( 260) 513 106.4 3.7e-23 CCDS41801.1 CTDSP2 gene_id:10106|Hs108|chr12 ( 271) 509 105.7 6.4e-23 CCDS2416.1 CTDSP1 gene_id:58190|Hs108|chr2 ( 261) 508 105.5 7.1e-23 CCDS11093.1 CTDNEP1 gene_id:23399|Hs108|chr17 ( 244) 406 86.4 3.7e-17 >>CCDS10110.1 CTDSPL2 gene_id:51496|Hs108|chr15 (466 aa) initn: 3051 init1: 3051 opt: 3051 Z-score: 3091.6 bits: 581.4 E(32554): 7e-166 Smith-Waterman score: 3051; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466) 10 20 30 40 50 60 pF1KB5 MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 MEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 CSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 CSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 NILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPI 370 380 390 400 410 420 430 440 450 460 pF1KB5 ESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD :::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD 430 440 450 460 >>CCDS33735.1 CTDSPL gene_id:10217|Hs108|chr3 (265 aa) initn: 564 init1: 291 opt: 538 Z-score: 554.4 bits: 111.1 E(32554): 1.5e-24 Smith-Waterman score: 538; 47.4% identity (73.4% similar) in 192 aa overlap (264-449:66-255) 240 250 260 270 280 pF1KB5 TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQ--LNRKPA---LP-LKTRSTPE .:::.::. :.. :: :: . . . . CCDS33 KQRSRSILSSFFCCFRDYNVEAPPPSSPSVLPPLVEENGGLQKPPAKYLLPEVTVLDYGK 40 50 60 70 80 90 290 300 310 320 330 340 pF1KB5 FSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIIL .:.:::::::: :.. . .: . :: .. .:.:::: :: :::.::.:..: .: CCDS33 KCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVL 100 110 120 130 140 150 350 360 370 380 390 400 pF1KB5 FTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSP :::: ::: . ..:: . . : ::::: :: .:::.:::. :::.:::.::.:::: CCDS33 FTASLAKYADPVADLLD-RWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSP 160 170 180 190 200 210 410 420 430 440 450 460 pF1KB5 QAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD .. .. :..:..::: : .:.::: ::::.: : . ..:: CCDS33 ASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSR-EDDVYSMLHRLCNR 220 230 240 250 260 >>CCDS33734.1 CTDSPL gene_id:10217|Hs108|chr3 (276 aa) initn: 564 init1: 291 opt: 516 Z-score: 531.9 bits: 107.0 E(32554): 2.6e-23 Smith-Waterman score: 521; 43.8% identity (70.0% similar) in 203 aa overlap (264-449:66-266) 240 250 260 270 280 pF1KB5 TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEE-----QLNRKPALPLKTRST--- .:::.:: . ... ..:. . . CCDS33 KQRSRSILSSFFCCFRDYNVEAPPPSSPSVLPPLVEENGGLQKGDQRQVIPIPSPPAKYL 40 50 60 70 80 90 290 300 310 320 330 pF1KB5 -PEFSL--------VLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFL :: .. :.:::::::: :.. . .: . :: .. .:.:::: :: ::: CCDS33 LPEVTVLDYGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFL 100 110 120 130 140 150 340 350 360 370 380 390 pF1KB5 ERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRD .::.:..: .::::: ::: . ..:: . . : ::::: :: .:::.:::. :::. CCDS33 QRMGQLFECVLFTASLAKYADPVADLLD-RWGVFRARLFRESCVFHRGNYVKDLSRLGRE 160 170 180 190 200 210 400 410 420 430 440 450 pF1KB5 LSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDR :::.::.:::: .. .. :..:..::: : .:.::: ::::.: : . ..:: CCDS33 LSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSR-EDDVYSMLHRL 220 230 240 250 260 270 460 pF1KB5 FRLHDLLPPD CCDS33 CNR >>CCDS56166.1 CTDSP1 gene_id:58190|Hs108|chr2 (260 aa) initn: 500 init1: 273 opt: 513 Z-score: 529.3 bits: 106.4 E(32554): 3.7e-23 Smith-Waterman score: 513; 43.4% identity (73.5% similar) in 196 aa overlap (265-454:61-254) 240 250 260 270 280 pF1KB5 PDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQ--LNRKPA---LP-LKTRSTPEF : :.::. . . :. :: :.... .. CCDS56 QKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKTPVQYLLPEAKAQDSDKI 40 50 60 70 80 90 290 300 310 320 330 340 pF1KB5 SLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILF .:.:::::::: :.. ...: . .:: .. :..:::: :: :::.::....: .:: CCDS56 CVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLF 100 110 120 130 140 150 350 360 370 380 390 400 pF1KB5 TASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQ ::: ::: . ..:: : : ::::: :: .:::.:::. ::::: ...:.:::: CCDS56 TASLAKYADPVADLLD-KWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPA 160 170 180 190 200 410 420 430 440 450 460 pF1KB5 AFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD ..... .:..:. ::: . .:.:: :.::.:.: ... :: .: CCDS56 SYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVD-DVYSVLRQPRPGS 210 220 230 240 250 260 >>CCDS41801.1 CTDSP2 gene_id:10106|Hs108|chr12 (271 aa) initn: 497 init1: 283 opt: 509 Z-score: 525.0 bits: 105.7 E(32554): 6.4e-23 Smith-Waterman score: 509; 41.5% identity (69.1% similar) in 217 aa overlap (238-449:51-261) 210 220 230 240 250 260 pF1KB5 RPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYSSAHAE-ATYEEDWEVFDPYYFIKHVPP : ::. .: :.:.:. ... ... . CCDS41 QGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCL-- 30 40 50 60 70 270 280 290 300 310 320 pF1KB5 LTEEQLNRKPALPLKTRSTPE----FSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIY . :. . :. : . : : . .:.:::::::: :.. ...: . :. .. . . CCDS41 --QYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTH 80 90 100 110 120 130 330 340 350 360 370 380 pF1KB5 QVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCV :::: ::. :::.::....: .::::: ::: . ..:: . . : ::::: :: CCDS41 QVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLD-RCGVFRARLFRESCVFH 140 150 160 170 180 190 390 400 410 420 430 440 pF1KB5 QGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKL :: :.:::. ::::: ::.:.:::: .. .. :..:..::: : :.:::.:::..:.: CCDS41 QGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEEL 200 210 220 230 240 250 450 460 pF1KB5 VELNEDVRPHIRDRFRLHDLLPPD ::: CCDS41 -SGAEDVYTSLGQLRAP 260 270 >>CCDS2416.1 CTDSP1 gene_id:58190|Hs108|chr2 (261 aa) initn: 500 init1: 273 opt: 508 Z-score: 524.2 bits: 105.5 E(32554): 7.1e-23 Smith-Waterman score: 508; 44.9% identity (75.3% similar) in 178 aa overlap (278-454:80-255) 250 260 270 280 290 300 pF1KB5 YEEDWEVFDPYYFIKHVPPLTEEQLNRKPALP-LKTRSTPEFSLVLDLDETLVHCSLNEL :: :.... .. .:.:::::::: :.. . CCDS24 DGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPV 50 60 70 80 90 100 310 320 330 340 350 360 pF1KB5 EDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPK ..: . .:: .. :..:::: :: :::.::....: .::::: ::: . ..:: : CCDS24 NNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLD-K 110 120 130 140 150 160 370 380 390 400 410 420 pF1KB5 KQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMD : ::::: :: .:::.:::. ::::: ...:.:::: ..... .:..:. ::: . CCDS24 WGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDN 170 180 190 200 210 220 430 440 450 460 pF1KB5 KNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD .:.:: :.::.:.: ... :: .: CCDS24 MSDTELHDLLPFFEQLSRVD-DVYSVLRQPRPGS 230 240 250 260 >>CCDS11093.1 CTDNEP1 gene_id:23399|Hs108|chr17 (244 aa) initn: 426 init1: 354 opt: 406 Z-score: 421.5 bits: 86.4 E(32554): 3.7e-17 Smith-Waterman score: 424; 35.0% identity (62.4% similar) in 226 aa overlap (252-462:21-243) 230 240 250 260 270 280 pF1KB5 VNRDIPPLTAPVTPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLK : : : . ... . . : : :::. CCDS11 MMRTQCLLGLRTFVAFAAKLWSFF-IYLLRRQIRTVIQYQTVRYDILPLS 10 20 30 40 290 300 310 320 pF1KB5 TRSTPEFS------LVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQV---------YV : ... :::::::::.: . . .. : : : .: .: CCDS11 PVSRNRLAQVKRKILVLDLDETLIHSHHDGVLRPTVR-PGTPPDFILKVVIDKHPVRFFV 50 60 70 80 90 100 330 340 350 360 370 380 pF1KB5 RLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNY . :: ::: .:: ::...:::: ..:.. . . :: .......: .:.::. :.: CCDS11 HKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNSRSILKRRYYRQHCTLELGSY 110 120 130 140 150 160 390 400 410 420 430 440 pF1KB5 IKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELN ::::... :::. .:.:::: :. . .:.:::.::: : .:. ::.:.:.:. : ... CCDS11 IKDLSVVHSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDAL-RFT 170 180 190 200 210 220 450 460 pF1KB5 EDVRPHIRDRFRLHDLLPPD ::: . .. : : CCDS11 ADVRSVLSRNLHQHRLW 230 240 466 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:43:00 2016 done: Thu Nov 3 22:43:00 2016 Total Scan time: 3.150 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]