FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5611, 382 aa 1>>>pF1KB5611 382 - 382 aa - 382 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3567+/-0.000813; mu= 16.2891+/- 0.049 mean_var=66.5338+/-13.041, 0's: 0 Z-trim(107.1): 25 B-trim: 0 in 0/51 Lambda= 0.157236 statistics sampled from 9336 (9360) to 9336 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.288), width: 16 Scan time: 2.840 The best scores are: opt bits E(32554) CCDS9744.1 PPM1A gene_id:5494|Hs108|chr14 ( 382) 2610 600.9 6e-172 CCDS45120.1 PPM1A gene_id:5494|Hs108|chr14 ( 455) 2610 601.0 7e-172 CCDS9745.1 PPM1A gene_id:5494|Hs108|chr14 ( 324) 2178 502.9 1.7e-142 CCDS1816.1 PPM1B gene_id:5495|Hs108|chr2 ( 387) 1997 461.9 4.4e-130 CCDS1817.1 PPM1B gene_id:5495|Hs108|chr2 ( 479) 1983 458.7 4.8e-129 CCDS46271.1 PPM1B gene_id:5495|Hs108|chr2 ( 380) 1980 458.0 6.3e-129 CCDS46115.1 PPM1N gene_id:147699|Hs108|chr19 ( 430) 1018 239.8 3.4e-63 CCDS1818.1 PPM1B gene_id:5495|Hs108|chr2 ( 192) 438 108.1 7e-24 CCDS33886.1 PPM1L gene_id:151742|Hs108|chr3 ( 360) 436 107.8 1.6e-23 CCDS1752.1 PPM1G gene_id:5496|Hs108|chr2 ( 546) 395 98.6 1.5e-20 CCDS3629.1 PPM1K gene_id:152926|Hs108|chr4 ( 372) 381 95.3 9.6e-20 CCDS82868.1 PPM1L gene_id:151742|Hs108|chr3 ( 233) 357 89.7 2.8e-18 CCDS82869.1 PPM1L gene_id:151742|Hs108|chr3 ( 181) 347 87.4 1.1e-17 CCDS2526.1 ILKAP gene_id:80895|Hs108|chr2 ( 392) 306 78.3 1.3e-14 CCDS13796.1 PPM1F gene_id:9647|Hs108|chr22 ( 454) 265 69.0 9.4e-12 CCDS11613.1 PPM1E gene_id:22843|Hs108|chr17 ( 755) 262 68.5 2.3e-11 >>CCDS9744.1 PPM1A gene_id:5494|Hs108|chr14 (382 aa) initn: 2610 init1: 2610 opt: 2610 Z-score: 3200.5 bits: 600.9 E(32554): 6e-172 Smith-Waterman score: 2610; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382) 10 20 30 40 50 60 pF1KB5 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 AVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEA 310 320 330 340 350 360 370 380 pF1KB5 VYNRLNPYKNDDTDSTSTDDMW :::::::::::::::::::::: CCDS97 VYNRLNPYKNDDTDSTSTDDMW 370 380 >>CCDS45120.1 PPM1A gene_id:5494|Hs108|chr14 (455 aa) initn: 2610 init1: 2610 opt: 2610 Z-score: 3199.3 bits: 601.0 E(32554): 7e-172 Smith-Waterman score: 2610; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:74-455) 10 20 30 pF1KB5 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQ :::::::::::::::::::::::::::::: CCDS45 ERRRNEKRGNQMKRMCERKKYETDLEDQDIMGAFLDKPKMEKHNAQGQGNGLRYGLSSMQ 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB5 GWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAG 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB5 APSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 APSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGL 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB5 LCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGP 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB5 TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNE 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB5 VVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEIIKKQGEGVPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEIIKKQGEGVPDL 350 360 370 380 390 400 340 350 360 370 380 pF1KB5 VHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW 410 420 430 440 450 >>CCDS9745.1 PPM1A gene_id:5494|Hs108|chr14 (324 aa) initn: 2178 init1: 2178 opt: 2178 Z-score: 2671.9 bits: 502.9 E(32554): 1.7e-142 Smith-Waterman score: 2178; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317) 10 20 30 40 50 60 pF1KB5 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEA ::::::::::::::::: CCDS97 AVKKEAELDKYLECRVEGGSFNKK 310 320 >>CCDS1816.1 PPM1B gene_id:5495|Hs108|chr2 (387 aa) initn: 1937 init1: 889 opt: 1997 Z-score: 2448.9 bits: 461.9 E(32554): 4.4e-130 Smith-Waterman score: 1997; 75.8% identity (90.2% similar) in 388 aa overlap (1-382:1-387) 10 20 30 40 50 60 pF1KB5 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD ::::::::: :::::.: :::::::::::::::::::::::::.:.: :::.:::::::: CCDS18 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM :::::.::.:: :::.:::.:.::. ::: ::::::::::::::.:::.:: . CCDS18 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI :. ..: ::::::::::.:::.: :::::::::..: :: .: : :::::: :: ::::: CCDS18 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII ::::::::::::::::::::::::.::::: :::::::::::::::..: :.:::. ::: CCDS18 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDE-FII 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP ::::::::::.:::::..:.:::::.::::.::: ::::::.::::::::..:.:: ::: CCDS18 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 KVSPEAVKKEAELDKYLECRVEEIIKKQGE-GVPDLVHVMRTLASENIPSLPPGGELASK ::: :::::..::::.:: :::::..:.:: :.:::.:::: :..::::.::::: ::.: CCDS18 KVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGK 300 310 320 330 340 350 360 370 380 pF1KB5 RNVIEAVYNRLNPYKNDDTDSTSTDDMW ::::::::.::::....: . . .: : CCDS18 RNVIEAVYSRLNPHRESDGGAGDLEDPW 360 370 380 >>CCDS1817.1 PPM1B gene_id:5495|Hs108|chr2 (479 aa) initn: 1940 init1: 892 opt: 1983 Z-score: 2430.3 bits: 458.7 E(32554): 4.8e-129 Smith-Waterman score: 1983; 75.9% identity (90.4% similar) in 386 aa overlap (1-380:1-385) 10 20 30 40 50 60 pF1KB5 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD ::::::::: :::::.: :::::::::::::::::::::::::.:.: :::.:::::::: CCDS18 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM :::::.::.:: :::.:::.:.::. ::: ::::::::::::::.:::.:: . CCDS18 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI :. ..: ::::::::::.:::.: :::::::::..: :: .: : :::::: :: ::::: CCDS18 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII ::::::::::::::::::::::::.::::: :::::::::::::::..: :.:::. ::: CCDS18 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDE-FII 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP ::::::::::.:::::..:.:::::.::::.::: ::::::.::::::::..:.:: ::: CCDS18 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 KVSPEAVKKEAELDKYLECRVEEIIKKQGE-GVPDLVHVMRTLASENIPSLPPGGELASK ::: :::::..::::.:: :::::..:.:: :.:::.:::: :..::::.::::: ::.: CCDS18 KVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGK 300 310 320 330 340 350 360 370 380 pF1KB5 RNVIEAVYNRLNPYKNDDTDSTSTDDMW ::::::::.::::....: : ... CCDS18 RNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYR 360 370 380 390 400 410 >>CCDS46271.1 PPM1B gene_id:5495|Hs108|chr2 (380 aa) initn: 1937 init1: 889 opt: 1980 Z-score: 2428.2 bits: 458.0 E(32554): 6.3e-129 Smith-Waterman score: 1980; 77.2% identity (91.3% similar) in 378 aa overlap (1-372:1-377) 10 20 30 40 50 60 pF1KB5 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD ::::::::: :::::.: :::::::::::::::::::::::::.:.: :::.:::::::: CCDS46 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM :::::.::.:: :::.:::.:.::. ::: ::::::::::::::.:::.:: . CCDS46 GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI :. ..: ::::::::::.:::.: :::::::::..: :: .: : :::::: :: ::::: CCDS46 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII ::::::::::::::::::::::::.::::: :::::::::::::::..: :.:::. ::: CCDS46 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDE-FII 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP ::::::::::.:::::..:.:::::.::::.::: ::::::.::::::::..:.:: ::: CCDS46 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 KVSPEAVKKEAELDKYLECRVEEIIKKQGE-GVPDLVHVMRTLASENIPSLPPGGELASK ::: :::::..::::.:: :::::..:.:: :.:::.:::: :..::::.::::: ::.: CCDS46 KVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGK 300 310 320 330 340 350 360 370 380 pF1KB5 RNVIEAVYNRLNPYKNDDTDSTSTDDMW ::::::::.::::....: CCDS46 RNVIEAVYSRLNPHRESDGQK 360 370 380 >>CCDS46115.1 PPM1N gene_id:147699|Hs108|chr19 (430 aa) initn: 684 init1: 366 opt: 1018 Z-score: 1248.0 bits: 239.8 E(32554): 3.4e-63 Smith-Waterman score: 1018; 44.4% identity (71.0% similar) in 365 aa overlap (3-365:44-399) 10 20 30 pF1KB5 MGAFLDKPKMEK--HNAQGQGNGLRYGLSSMQ ..: :. . :.. ..:::.: :. : CCDS46 TACKKKEREKEGREEEEEEEAGRRAPEGPRSLLTAPRRAQRPHGGAEASGGLRFGASAAQ 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 GWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAG :::..::::: . ..::. .:..::: :::.:...:.. .:: :. :.. . CCDS46 GWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGARHLPGHVL--QELGPEPS 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 APSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGL : :.:....: .:: ::..: . . .. .: ::: .:.::. :. .:::::.. CCDS46 EP--EGVREALRRAFLSADERLRSLWPR---VETGGCTAVVLLVSPRFLYLAHCGDSRAV 140 150 160 170 180 160 170 180 190 200 210 pF1KB5 LCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGP : : : : :.::.: : :.:::. :::.. .::.:::::::::::: :: . :. : CCDS46 LSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPGRPP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB5 TEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNE :::: :::: . :. ::. :..:: ::.::.... : .: :::.. : .: . CCDS46 ELQLVSAEPEVAALARQAEDE-FMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB5 VVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEIIKKQGEGVPDL ..:::: ::: :::. ::.:::.::. : ::...: :: : ::. :. . .. :.: CCDS46 LLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELALDAALGCRIAELCAS-AQKPPSL 310 320 330 340 350 360 340 350 360 370 380 pF1KB5 VHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW :.::::::.::.::::: : : .:: ::... CCDS46 NTVFRTLASEDIPDLPPGGGLDCKATVIAEVYSQICQVSEECGEKGQDGAGKSNPTHLGS 370 380 390 400 410 420 CCDS46 ALDMEA 430 >>CCDS1818.1 PPM1B gene_id:5495|Hs108|chr2 (192 aa) initn: 442 init1: 250 opt: 438 Z-score: 542.2 bits: 108.1 E(32554): 7e-24 Smith-Waterman score: 438; 66.3% identity (89.8% similar) in 98 aa overlap (284-380:1-98) 260 270 280 290 300 310 pF1KB5 VRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLE ::..:.:: :::::: :::::..::::.:: CCDS18 MSIVLVCFSNAPKVSDEAVKKDSELDKHLE 10 20 30 320 330 340 350 360 370 pF1KB5 CRVEEIIKKQGE-GVPDLVHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDD :::::..:.:: :.:::.:::: :..::::.::::: ::.:::::::::.::::....: CCDS18 SRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESD 40 50 60 70 80 90 380 pF1KB5 TDSTSTDDMW : ... CCDS18 GASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATAT 100 110 120 130 140 150 >>CCDS33886.1 PPM1L gene_id:151742|Hs108|chr3 (360 aa) initn: 360 init1: 97 opt: 436 Z-score: 535.6 bits: 107.8 E(32554): 1.6e-23 Smith-Waterman score: 436; 31.4% identity (63.9% similar) in 274 aa overlap (28-296:97-356) 10 20 30 40 50 pF1KB5 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFA :.:: : .::: .. : . . :.:. CCDS33 MQNDRLGGLDVLEAEFSKTWEFKNHNVAVYSIQGRRDHMEDRFEVLTDLANKTHP-SIFG 70 80 90 100 110 120 60 70 80 90 100 110 pF1KB5 VYDGHAGSQVAKYCCEHLLDHITNN-QDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMS ..:::.: .:.: .: . . .. ::.. . :: . .. .. .: ::..: . CCDS33 IFDGHGGETAAEYVKSRLPEALKQHLQDYEKDK-ENSVLSYQTILEQQILSIDREM--LE 130 140 150 160 170 180 120 130 140 150 160 170 pF1KB5 EKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLC-RNRKVHFFTQDHKPSNPLEKERI . . :..:.: . .:.: . : :::::.:: .. .. ...:::: . :..:: CCDS33 KLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRI 190 200 210 220 230 240 180 190 200 210 220 230 pF1KB5 QNAGGSVMIQ---RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQ . ::: . .. ::.: ::.::.:::. : .. .: :.:.. .. .. . . CCDS33 KRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLN-------VVIPDPDILTFDLDKLQPE 250 260 270 280 290 240 250 260 270 280 290 pF1KB5 FIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFP :.::: ::.::...::: :.. :: :. . . .: .:.: ::..:... : CCDS33 FMILASDGLWDAFSNEEAVRFIKERL---DEPHFGAKSIVLQSFYRGCPDNITVMVVKFR 300 310 320 330 340 350 300 310 320 330 340 350 pF1KB5 NAPKVSPEAVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELA :. : CCDS33 NSSKTEEQ 360 >>CCDS1752.1 PPM1G gene_id:5496|Hs108|chr2 (546 aa) initn: 544 init1: 226 opt: 395 Z-score: 482.6 bits: 98.6 E(32554): 1.5e-20 Smith-Waterman score: 447; 37.2% identity (66.1% similar) in 218 aa overlap (107-307:307-523) 80 90 100 110 120 130 pF1KB5 DHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRV--MSEKKHGADRSGSTAVGVLI : .:.: : : :.. .. ::.::: .:: CCDS17 CSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALI 280 290 300 310 320 330 140 150 160 170 180 190 pF1KB5 SPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQ-RVNGSLAV .. : :::: .. . :. .. :::: . .: ::.::::.: .. ::::.: . CCDS17 RGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNL 340 350 360 370 380 390 200 210 220 230 240 250 pF1KB5 SRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDF :::.:: :: .. : ::..: :... . .: .:...::::::.::...:. :: CCDS17 SRAIGDHFYKRNKNLPPEEQMISALPDIK-VLTLTDDHEFMVIACDGIWNVMSSQEVVDF 400 410 420 430 440 450 260 270 280 290 pF1KB5 VRSRLEVTDD------LEKVCNEVVDTCLYKGSR------DNMSVILICF-P-NAPKVSP ..:.. :. : .. .:..: :: . :::. :.::: : :. ...: CCDS17 IQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQP 460 470 480 490 500 510 300 310 320 330 340 350 pF1KB5 EAVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIE :. :.. : CCDS17 ESGKRKLEEVLSTEGAEENGNSDKKKKAKRD 520 530 540 382 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:43:42 2016 done: Thu Nov 3 22:43:43 2016 Total Scan time: 2.840 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]