FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5628, 1376 aa 1>>>pF1KB5628 1376 - 1376 aa - 1376 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.3472+/-0.000419; mu= -10.5173+/- 0.026 mean_var=299.3529+/-62.620, 0's: 0 Z-trim(121.2): 149 B-trim: 830 in 1/58 Lambda= 0.074128 statistics sampled from 37232 (37391) to 37232 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.438), width: 16 Scan time: 17.880 The best scores are: opt bits E(85289) NP_002917 (OMIM: 602512) regulator of G-protein si (1376) 9253 1004.0 0 XP_016864018 (OMIM: 602512) PREDICTED: regulator o (1447) 9230 1001.6 0 NP_937872 (OMIM: 602512) regulator of G-protein si (1447) 9230 1001.6 0 XP_006713968 (OMIM: 602512) PREDICTED: regulator o (1447) 9230 1001.6 0 XP_006713969 (OMIM: 602512) PREDICTED: regulator o (1157) 7661 833.7 0 NP_937870 (OMIM: 602512) regulator of G-protein si ( 799) 4680 514.9 9.4e-145 XP_016864019 (OMIM: 602512) PREDICTED: regulator o ( 840) 4568 502.9 4e-141 XP_011511845 (OMIM: 602512) PREDICTED: regulator o ( 646) 3767 417.2 1.9e-115 XP_016864020 (OMIM: 602512) PREDICTED: regulator o ( 646) 3767 417.2 1.9e-115 XP_006713970 (OMIM: 602512) PREDICTED: regulator o ( 646) 3767 417.2 1.9e-115 XP_016864022 (OMIM: 602512) PREDICTED: regulator o ( 646) 3767 417.2 1.9e-115 XP_016864021 (OMIM: 602512) PREDICTED: regulator o ( 646) 3767 417.2 1.9e-115 XP_016864023 (OMIM: 602512) PREDICTED: regulator o ( 509) 3111 347.0 2e-94 NP_006471 (OMIM: 602513) regulator of G-protein si ( 566) 704 89.6 6.9e-17 XP_005265851 (OMIM: 602513) PREDICTED: regulator o ( 567) 704 89.6 6.9e-17 XP_005265852 (OMIM: 602513) PREDICTED: regulator o ( 467) 689 88.0 1.8e-16 NP_002916 (OMIM: 602856) regulator of G-protein si ( 167) 487 66.3 2.2e-10 NP_001005339 (OMIM: 602856) regulator of G-protein ( 181) 487 66.3 2.4e-10 XP_016857501 (OMIM: 602517) PREDICTED: regulator o ( 393) 345 51.2 1.8e-05 NP_001269702 (OMIM: 602517) regulator of G-protein ( 424) 345 51.2 1.9e-05 XP_016857495 (OMIM: 602517) PREDICTED: regulator o ( 451) 345 51.2 2e-05 XP_016857496 (OMIM: 602517) PREDICTED: regulator o ( 451) 345 51.2 2e-05 XP_016857494 (OMIM: 602517) PREDICTED: regulator o ( 451) 345 51.2 2e-05 XP_016857492 (OMIM: 602517) PREDICTED: regulator o ( 460) 345 51.2 2.1e-05 NP_001269704 (OMIM: 602517) regulator of G-protein ( 477) 345 51.2 2.1e-05 XP_016877310 (OMIM: 603894) PREDICTED: regulator o ( 554) 345 51.2 2.4e-05 NP_001273415 (OMIM: 603895) regulator of G-protein ( 283) 335 50.1 2.8e-05 XP_016857502 (OMIM: 602517) PREDICTED: regulator o ( 385) 336 50.2 3.4e-05 NP_001106851 (OMIM: 602516) regulator of G-protein ( 187) 326 49.1 3.7e-05 XP_016857498 (OMIM: 602517) PREDICTED: regulator o ( 443) 336 50.3 3.9e-05 XP_016857497 (OMIM: 602517) PREDICTED: regulator o ( 443) 336 50.3 3.9e-05 XP_016857499 (OMIM: 602517) PREDICTED: regulator o ( 443) 336 50.3 3.9e-05 XP_016857493 (OMIM: 602517) PREDICTED: regulator o ( 452) 336 50.3 4e-05 NP_005604 (OMIM: 602516) regulator of G-protein si ( 205) 326 49.1 4e-05 NP_001269707 (OMIM: 602517) regulator of G-protein ( 469) 336 50.3 4.1e-05 NP_003825 (OMIM: 603895) regulator of G-protein si ( 446) 335 50.1 4.2e-05 NP_001273414 (OMIM: 603895) regulator of G-protein ( 456) 335 50.1 4.3e-05 NP_899180 (OMIM: 603895) regulator of G-protein si ( 467) 335 50.2 4.4e-05 XP_011521022 (OMIM: 603895) PREDICTED: regulator o ( 478) 335 50.2 4.5e-05 XP_011521021 (OMIM: 603895) PREDICTED: regulator o ( 499) 335 50.2 4.7e-05 NP_036551 (OMIM: 607191) regulator of G-protein si ( 210) 324 48.9 4.8e-05 NP_001095915 (OMIM: 602516) regulator of G-protein ( 302) 328 49.3 4.9e-05 XP_005260240 (OMIM: 605071) PREDICTED: regulator o ( 195) 322 48.7 5.2e-05 XP_005260239 (OMIM: 605071) PREDICTED: regulator o ( 195) 322 48.7 5.2e-05 NP_005864 (OMIM: 605071) regulator of G-protein si ( 217) 322 48.7 5.7e-05 NP_001034556 (OMIM: 605071) regulator of G-protein ( 217) 322 48.7 5.7e-05 XP_011526787 (OMIM: 605071) PREDICTED: regulator o ( 217) 322 48.7 5.7e-05 XP_011526788 (OMIM: 605071) PREDICTED: regulator o ( 217) 322 48.7 5.7e-05 XP_011526786 (OMIM: 605071) PREDICTED: regulator o ( 246) 322 48.7 6.4e-05 XP_011523728 (OMIM: 604067,608415) PREDICTED: regu ( 478) 327 49.3 8.1e-05 >>NP_002917 (OMIM: 602512) regulator of G-protein signal (1376 aa) initn: 9253 init1: 9253 opt: 9253 Z-score: 5358.9 bits: 1004.0 E(85289): 0 Smith-Waterman score: 9253; 100.0% identity (100.0% similar) in 1376 aa overlap (1-1376:1-1376) 10 20 30 40 50 60 pF1KB5 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB5 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB5 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB5 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB5 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB5 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB5 RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB5 WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB5 SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGTSRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGTSRF 1330 1340 1350 1360 1370 >>XP_016864018 (OMIM: 602512) PREDICTED: regulator of G- (1447 aa) initn: 9300 init1: 9230 opt: 9230 Z-score: 5345.3 bits: 1001.6 E(85289): 0 Smith-Waterman score: 9230; 99.9% identity (100.0% similar) in 1373 aa overlap (1-1373:1-1373) 10 20 30 40 50 60 pF1KB5 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB5 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB5 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB5 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB5 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB5 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB5 RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB5 WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB5 SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGTSRF ::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGSGTHGSRD 1330 1340 1350 1360 1370 1380 XP_016 LPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGRSQASGGPPTSDLPGLGPVPGEPAKPKTS 1390 1400 1410 1420 1430 1440 >>NP_937872 (OMIM: 602512) regulator of G-protein signal (1447 aa) initn: 9300 init1: 9230 opt: 9230 Z-score: 5345.3 bits: 1001.6 E(85289): 0 Smith-Waterman score: 9230; 99.9% identity (100.0% similar) in 1373 aa overlap (1-1373:1-1373) 10 20 30 40 50 60 pF1KB5 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB5 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB5 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB5 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB5 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB5 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB5 RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB5 WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB5 SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGTSRF ::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_937 SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGSGTHGSRD 1330 1340 1350 1360 1370 1380 NP_937 LPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGRSQASGGPPTSDLPGLGPVPGEPAKPKTS 1390 1400 1410 1420 1430 1440 >>XP_006713968 (OMIM: 602512) PREDICTED: regulator of G- (1447 aa) initn: 9300 init1: 9230 opt: 9230 Z-score: 5345.3 bits: 1001.6 E(85289): 0 Smith-Waterman score: 9230; 99.9% identity (100.0% similar) in 1373 aa overlap (1-1373:1-1373) 10 20 30 40 50 60 pF1KB5 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB5 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB5 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB5 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB5 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB5 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB5 RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB5 WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KB5 SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGTSRF ::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_006 SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGSGTHGSRD 1330 1340 1350 1360 1370 1380 XP_006 LPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGRSQASGGPPTSDLPGLGPVPGEPAKPKTS 1390 1400 1410 1420 1430 1440 >>XP_006713969 (OMIM: 602512) PREDICTED: regulator of G- (1157 aa) initn: 7661 init1: 7661 opt: 7661 Z-score: 4440.0 bits: 833.7 E(85289): 0 Smith-Waterman score: 7661; 100.0% identity (100.0% similar) in 1137 aa overlap (1-1137:1-1137) 10 20 30 40 50 60 pF1KB5 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB5 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB5 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB5 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB5 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB5 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB5 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB5 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATSFL 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB5 RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN XP_006 SLFPKLRATEQMTNVGC 1150 >>NP_937870 (OMIM: 602512) regulator of G-protein signal (799 aa) initn: 4740 init1: 4670 opt: 4680 Z-score: 2719.7 bits: 514.9 E(85289): 9.4e-145 Smith-Waterman score: 4680; 99.4% identity (99.9% similar) in 711 aa overlap (663-1373:15-725) 640 650 660 670 680 690 pF1KB5 RGTGLTQPSQRTSARRSFGRSKRFSITRSLDDLESATVSDGELTGADLKDCVSNNSLSSN .: .:::::::::::::::::::::::::: NP_937 MNLGKELSNETHVSNDQQSATVSDGELTGADLKDCVSNNSLSSN 10 20 30 40 700 710 720 730 740 750 pF1KB5 ASLPSVQSCRRLRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 ASLPSVQSCRRLRERRVASWAVSFERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFN 50 60 70 80 90 100 760 770 780 790 800 810 pF1KB5 HVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 HVPAHDKKELSYRAREIFSKFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFN 110 120 130 140 150 160 820 830 840 850 860 870 pF1KB5 LMKFDSYTRFLKSPLYQECILAEVEGRALPDSQQVPSSPASKHSLGSDHSSVSTPKKLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 LMKFDSYTRFLKSPLYQECILAEVEGRALPDSQQVPSSPASKHSLGSDHSSVSTPKKLSG 170 180 190 200 210 220 880 890 900 910 920 930 pF1KB5 KSKSGRSLNEELGDEDSEKKRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KSKSGRSLNEELGDEDSEKKRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRR 230 240 250 260 270 280 940 950 960 970 980 990 pF1KB5 ESQGSVSSAGSLDLSEACRTLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 ESQGSVSSAGSLDLSEACRTLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLC 290 300 310 320 330 340 1000 1010 1020 1030 1040 1050 pF1KB5 ERHGINGAAADLFLVGGDKPLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 ERHGINGAAADLFLVGGDKPLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKP 350 360 370 380 390 400 1060 1070 1080 1090 1100 1110 pF1KB5 TKPVTEVLRPVVARYGLDLSGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 TKPVTEVLRPVVARYGLDLSGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKAS 410 420 430 440 450 460 1120 1130 1140 1150 1160 1170 pF1KB5 ADKQKGVPVKQNTAVNSSSRNHSATGEERTLGKSNSIKIKGENGKNARDPRLSKREESIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 ADKQKGVPVKQNTAVNSSSRNHSATGEERTLGKSNSIKIKGENGKNARDPRLSKREESIA 470 480 490 500 510 520 1180 1190 1200 1210 1220 1230 pF1KB5 KIGKKKYQKINLDEAEEFFELISKAQSNRADDQRGLLRKEDLVLPEFLRLPPGSTELTLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KIGKKKYQKINLDEAEEFFELISKAQSNRADDQRGLLRKEDLVLPEFLRLPPGSTELTLP 530 540 550 560 570 580 1240 1250 1260 1270 1280 1290 pF1KB5 TPAAVAKGFSKRSATGNGRESASQPGEQWEPVQESSDSPSTSPGSASSPPGPPGTTPPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 TPAAVAKGFSKRSATGNGRESASQPGEQWEPVQESSDSPSTSPGSASSPPGPPGTTPPGQ 590 600 610 620 630 640 1300 1310 1320 1330 1340 1350 pF1KB5 KSPSGPFCTPQSPVSLAQEGTAQIWKRQSQEVEAGGIQTVEDEHVAELTLMGEGDISSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_937 KSPSGPFCTPQSPVSLAQEGTAQIWKRQSQEVEAGGIQTVEDEHVAELTLMGEGDISSPN 650 660 670 680 690 700 1360 1370 pF1KB5 STLLPPPSTPQEVPGPSRPGTSRF ::::::::::::::::::::. NP_937 STLLPPPSTPQEVPGPSRPGSGTHGSRDLPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGR 710 720 730 740 750 760 >>XP_016864019 (OMIM: 602512) PREDICTED: regulator of G- (840 aa) initn: 4628 init1: 4562 opt: 4568 Z-score: 2654.6 bits: 502.9 E(85289): 4e-141 Smith-Waterman score: 4568; 95.9% identity (97.2% similar) in 704 aa overlap (1-699:1-704) 10 20 30 40 50 60 pF1KB5 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 SLDDLE--SATVSDGELTGADLKDCVSNNS---LSSNASLPSVQSCRRLRERRVASWAVS :::::: : . : . ... :. .: .:: : : .: XP_016 SLDDLEPSSPASSPALISSPHLQPSSPASSPALISSLISSPHLQPSSPASSPASSPASSP 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB5 FERLLQDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLC XP_016 ALISSLISSLISIPHLQPSSPASSPALISSLISSPHLQPSSPASSPALISSLISSPHLQP 730 740 750 760 770 780 >>XP_011511845 (OMIM: 602512) PREDICTED: regulator of G- (646 aa) initn: 3837 init1: 3767 opt: 3767 Z-score: 2193.6 bits: 417.2 E(85289): 1.9e-115 Smith-Waterman score: 3767; 99.8% identity (100.0% similar) in 572 aa overlap (802-1373:1-572) 780 790 800 810 820 830 pF1KB5 KFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQEC :::::::::::::::::::::::::::::: XP_011 MFKEQQLQIFNLMKFDSYTRFLKSPLYQEC 10 20 30 840 850 860 870 880 890 pF1KB5 ILAEVEGRALPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILAEVEGRALPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEK 40 50 60 70 80 90 900 910 920 930 940 950 pF1KB5 KRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACR 100 110 120 130 140 150 960 970 980 990 1000 1010 pF1KB5 TLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDK 160 170 180 190 200 210 1020 1030 1040 1050 1060 1070 pF1KB5 PLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDL 220 230 240 250 260 270 1080 1090 1100 1110 1120 1130 pF1KB5 SGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSS 280 290 300 310 320 330 1140 1150 1160 1170 1180 1190 pF1KB5 RNHSATGEERTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNHSATGEERTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFF 340 350 360 370 380 390 1200 1210 1220 1230 1240 1250 pF1KB5 ELISKAQSNRADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELISKAQSNRADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGR 400 410 420 430 440 450 1260 1270 1280 1290 1300 1310 pF1KB5 ESASQPGEQWEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESASQPGEQWEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQE 460 470 480 490 500 510 1320 1330 1340 1350 1360 1370 pF1KB5 GTAQIWKRQSQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTAQIWKRQSQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRP 520 530 540 550 560 570 pF1KB5 GTSRF :. XP_011 GSGTHGSRDLPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGRSQASGGPPTSDLPGLGPVP 580 590 600 610 620 630 >>XP_016864020 (OMIM: 602512) PREDICTED: regulator of G- (646 aa) initn: 3837 init1: 3767 opt: 3767 Z-score: 2193.6 bits: 417.2 E(85289): 1.9e-115 Smith-Waterman score: 3767; 99.8% identity (100.0% similar) in 572 aa overlap (802-1373:1-572) 780 790 800 810 820 830 pF1KB5 KFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQEC :::::::::::::::::::::::::::::: XP_016 MFKEQQLQIFNLMKFDSYTRFLKSPLYQEC 10 20 30 840 850 860 870 880 890 pF1KB5 ILAEVEGRALPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILAEVEGRALPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEK 40 50 60 70 80 90 900 910 920 930 940 950 pF1KB5 KRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACR 100 110 120 130 140 150 960 970 980 990 1000 1010 pF1KB5 TLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDK 160 170 180 190 200 210 1020 1030 1040 1050 1060 1070 pF1KB5 PLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDL 220 230 240 250 260 270 1080 1090 1100 1110 1120 1130 pF1KB5 SGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSS 280 290 300 310 320 330 1140 1150 1160 1170 1180 1190 pF1KB5 RNHSATGEERTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNHSATGEERTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFF 340 350 360 370 380 390 1200 1210 1220 1230 1240 1250 pF1KB5 ELISKAQSNRADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELISKAQSNRADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGR 400 410 420 430 440 450 1260 1270 1280 1290 1300 1310 pF1KB5 ESASQPGEQWEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESASQPGEQWEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQE 460 470 480 490 500 510 1320 1330 1340 1350 1360 1370 pF1KB5 GTAQIWKRQSQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTAQIWKRQSQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRP 520 530 540 550 560 570 pF1KB5 GTSRF :. XP_016 GSGTHGSRDLPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGRSQASGGPPTSDLPGLGPVP 580 590 600 610 620 630 >>XP_006713970 (OMIM: 602512) PREDICTED: regulator of G- (646 aa) initn: 3837 init1: 3767 opt: 3767 Z-score: 2193.6 bits: 417.2 E(85289): 1.9e-115 Smith-Waterman score: 3767; 99.8% identity (100.0% similar) in 572 aa overlap (802-1373:1-572) 780 790 800 810 820 830 pF1KB5 KFLCSKATTPVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQEC :::::::::::::::::::::::::::::: XP_006 MFKEQQLQIFNLMKFDSYTRFLKSPLYQEC 10 20 30 840 850 860 870 880 890 pF1KB5 ILAEVEGRALPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILAEVEGRALPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEK 40 50 60 70 80 90 900 910 920 930 940 950 pF1KB5 KRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRKGAFFSWSRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACR 100 110 120 130 140 150 960 970 980 990 1000 1010 pF1KB5 TLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLAPEKDKATKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDK 160 170 180 190 200 210 1020 1030 1040 1050 1060 1070 pF1KB5 PLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLVLHQDSSILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDL 220 230 240 250 260 270 1080 1090 1100 1110 1120 1130 pF1KB5 SGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGLLVRLSGEKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSS 280 290 300 310 320 330 1140 1150 1160 1170 1180 1190 pF1KB5 RNHSATGEERTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RNHSATGEERTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFF 340 350 360 370 380 390 1200 1210 1220 1230 1240 1250 pF1KB5 ELISKAQSNRADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELISKAQSNRADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGR 400 410 420 430 440 450 1260 1270 1280 1290 1300 1310 pF1KB5 ESASQPGEQWEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ESASQPGEQWEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQE 460 470 480 490 500 510 1320 1330 1340 1350 1360 1370 pF1KB5 GTAQIWKRQSQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTAQIWKRQSQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRP 520 530 540 550 560 570 pF1KB5 GTSRF :. XP_006 GSGTHGSRDLPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGRSQASGGPPTSDLPGLGPVP 580 590 600 610 620 630 1376 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:19:52 2016 done: Sat Nov 5 07:19:54 2016 Total Scan time: 17.880 Total Display time: 0.490 Function used was FASTA [36.3.4 Apr, 2011]