FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5632, 269 aa 1>>>pF1KB5632 269 - 269 aa - 269 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3674+/-0.000811; mu= 15.3985+/- 0.049 mean_var=82.7496+/-16.592, 0's: 0 Z-trim(108.9): 53 B-trim: 108 in 1/51 Lambda= 0.140991 statistics sampled from 10486 (10538) to 10486 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.324), width: 16 Scan time: 2.250 The best scores are: opt bits E(32554) CCDS1264.1 MPZL1 gene_id:9019|Hs108|chr1 ( 269) 1776 370.6 6.4e-103 CCDS44273.1 MPZL1 gene_id:9019|Hs108|chr1 ( 209) 1333 280.4 7.1e-76 CCDS53425.1 MPZL1 gene_id:9019|Hs108|chr1 ( 119) 547 120.3 6.2e-28 CCDS1229.2 MPZ gene_id:4359|Hs108|chr1 ( 248) 426 96.0 2.8e-20 CCDS8393.1 MPZL2 gene_id:10205|Hs108|chr11 ( 215) 349 80.3 1.3e-15 CCDS8392.1 MPZL3 gene_id:196264|Hs108|chr11 ( 235) 307 71.8 5.1e-13 CCDS66241.1 MPZL3 gene_id:196264|Hs108|chr11 ( 223) 300 70.3 1.3e-12 >>CCDS1264.1 MPZL1 gene_id:9019|Hs108|chr1 (269 aa) initn: 1776 init1: 1776 opt: 1776 Z-score: 1961.2 bits: 370.6 E(32554): 6.4e-103 Smith-Waterman score: 1776; 100.0% identity (100.0% similar) in 269 aa overlap (1-269:1-269) 10 20 30 40 50 60 pF1KB5 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVI 190 200 210 220 230 240 250 260 pF1KB5 YAQLDHSGGHHSDKINKSESVVYADIRKN ::::::::::::::::::::::::::::: CCDS12 YAQLDHSGGHHSDKINKSESVVYADIRKN 250 260 >>CCDS44273.1 MPZL1 gene_id:9019|Hs108|chr1 (209 aa) initn: 1349 init1: 1333 opt: 1333 Z-score: 1475.7 bits: 280.4 E(32554): 7.1e-76 Smith-Waterman score: 1333; 98.5% identity (99.5% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KB5 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVI :::::::::::::::::::::: .. CCDS44 LLISMILAVLYRRKNSKRDYTGAQSYMHS 190 200 >>CCDS53425.1 MPZL1 gene_id:9019|Hs108|chr1 (119 aa) initn: 754 init1: 547 opt: 547 Z-score: 615.0 bits: 120.3 E(32554): 6.2e-28 Smith-Waterman score: 547; 100.0% identity (100.0% similar) in 86 aa overlap (1-86:1-86) 10 20 30 40 50 60 pF1KB5 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI :::::::::::::::::::::::::: CCDS53 KSTSTTGGLTSVSWSFQPEGADTTVSGPVIYAQLDHSGGHHSDKINKSESVVYADIRKN 70 80 90 100 110 >>CCDS1229.2 MPZ gene_id:4359|Hs108|chr1 (248 aa) initn: 494 init1: 382 opt: 426 Z-score: 477.6 bits: 96.0 E(32554): 2.8e-20 Smith-Waterman score: 455; 37.4% identity (67.4% similar) in 227 aa overlap (23-247:13-226) 10 20 30 40 50 pF1KB5 MAASAGAGAVIAAPDSRRWLWSVLAAAL--GLLTAGVSALEVYTPKEIFVANGTQGKLTC .::. : .:. . ..:. ::: .:. : :.. : : CCDS12 MAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHC 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 KFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDA .: :. .. : .: .::::. ..:.:::..:: :. . ::.::.:.:: ::. CCDS12 SFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 SINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLG :: :.:... :::. :::::::::: . ... ::: :: .:. ::.: : . ::: CCDS12 SIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEK--VPTR-YGVVLGAVIGGVLG 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 LTLLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGP ..::. ... :. : .:. . .. :: .... ..:. :. . ..: : CCDS12 VVLLLLLLFYVV-RYCWLRRQ---AALQRRLSAMEKGKLHKPG------KDASKRGRQTP 170 180 190 200 210 240 250 260 pF1KB5 VIYAQLDHSGGHHSDKINKSESVVYADIRKN :.::.:::: CCDS12 VLYAMLDHSRSTKAVSEKKAKGLGESRKDKK 220 230 240 >>CCDS8393.1 MPZL2 gene_id:10205|Hs108|chr11 (215 aa) initn: 295 init1: 200 opt: 349 Z-score: 393.8 bits: 80.3 E(32554): 1.3e-15 Smith-Waterman score: 349; 37.2% identity (66.3% similar) in 172 aa overlap (28-194:14-181) 10 20 30 40 50 pF1KB5 MAASAGAGAVIAAPDSRRWLWSVLAAALGL-LTA--GVSALEVYTPKEIFVANGTQGKLT ::. ::: ..:.:.:: . . ..:::...: CCDS83 MYGKSSTRAVLLLLGIQLTALWPIAAVEIYTSRVLEAVNGTDARLK 10 20 30 40 60 70 80 90 100 110 pF1KB5 CKFKSTSTTGGLTSVSWSFQPE--GADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDK : :.: . .: .:.:.:.: : . : ..: . : . : ::::.:: :. .. CCDS83 CTFSSFAPVGDALTVTWNFRPLDGGPEQFVFYYHIDPFQPMSGR---FKDRVSWDGNPER 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB5 KDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAV :::: . ..:: :::: :.::::::. :.::: ::. . . .....: .: CCDS83 YDASILLWKLQFDDNGTYTCQVKNPPDVDGVIGEIRLSVVHTVRFSEIH-FLALAIGSAC 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 VLGLTLLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSH .: . ..: ..: ::.: CCDS83 ALMIIIVIVVVLFQHYRKKRWAERAHKVVEIKSKEEERLNQEKKVSVYLEDTD 170 180 190 200 210 >>CCDS8392.1 MPZL3 gene_id:196264|Hs108|chr11 (235 aa) initn: 292 init1: 174 opt: 307 Z-score: 347.1 bits: 71.8 E(32554): 5.1e-13 Smith-Waterman score: 307; 35.1% identity (60.9% similar) in 174 aa overlap (35-204:29-200) 10 20 30 40 50 60 pF1KB5 AGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKFKSTS : .::. . .. : . :: : ::::: CCDS83 MQQRGAAGSRGCALFPLLGVLFFQGVYIVFSLEIRADAHVRGYVGEKIKLKCTFKSTS 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 TTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIEN . ...:...: ... :::.:::.. : : . :.:::::.:.. : ::::.: : CCDS83 DVTDKLTIDWTYRPPSSSHTVSIFHYQSFQ-YPTTAGTFRDRISWVGNVYKGDASISISN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 MQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFP----VWVVVGIVTAVVLGLT . :::. : ::::::. . .: :.:. .. . ..: . .:::..: CCDS83 PTIKDNGTFSCAVKNPPDVHHNIPMTELTVTERGFGTMLSSVALLSILVFVPSAVVVAL- 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 LLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVI ::. : . .: :. : : CCDS83 LLVRMGRKAAGLKKRSRSGYKKSSIEVSDDTDQEEEEACMARLCVRCAECLDSDYEETY 180 190 200 210 220 230 >>CCDS66241.1 MPZL3 gene_id:196264|Hs108|chr11 (223 aa) initn: 283 init1: 174 opt: 300 Z-score: 339.8 bits: 70.3 E(32554): 1.3e-12 Smith-Waterman score: 300; 37.3% identity (61.4% similar) in 158 aa overlap (51-204:33-188) 30 40 50 60 70 80 pF1KB5 WSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEG : . :: : ::::: . ...:...: . CCDS66 QRGAAGSRGCALFPLLGVLFFQDAHVRGYVGEKIKLKCTFKSTSDVTDKLTIDWTYRPPS 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB5 ADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNP .. :::.:::.. : : . :.:::::.:.. : ::::.: : . :::. : :::: CCDS66 SSHTVSIFHYQSFQ-YPTTAGTFRDRISWVGNVYKGDASISISNPTIKDNGTFSCAVKNP 70 80 90 100 110 120 150 160 170 180 190 pF1KB5 PDIVVQPGHIRLYVVEK---ENLPVFPVW-VVVGIVTAVVLGLTLLISMILAVLYRRKNS ::. . .: :.:. : . ..: . .:::..: ::. : . .: : CCDS66 PDVHHNIPMTELTVTERGFGTMLSSVALLSILVFVPSAVVVAL-LLVRMGRKAAGLKKRS 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB5 KRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVIYAQLDHSGGHHSDKIN . : : CCDS66 RSGYKKSSIEVSDDTDQEEEEACMARLCVRCAECLDSDYEETY 190 200 210 220 269 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:08:26 2016 done: Sat Nov 5 13:08:27 2016 Total Scan time: 2.250 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]