Result of FASTA (ccds) for
pF1KB5639
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5639, 440 aa
1>>>pF1KB5639 440 - 440 aa - 440 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0851+/-0.000734; mu= 15.7304+/- 0.044
mean_var=115.0102+/-22.372, 0's: 0 Z-trim(113.3): 38 B-trim: 4 in 1/49
Lambda= 0.119593
statistics sampled from 13912 (13950) to 13912 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.775), E-opt: 0.2 (0.429), width: 16
Scan time: 3.270
The best scores are: opt bits E(32554)
CCDS6035.1 TNFRSF10B gene_id:8795|Hs108|chr8 ( 440) 2988 526.1 2.8e-149
CCDS6036.1 TNFRSF10B gene_id:8795|Hs108|chr8 ( 411) 1504 270.0 3.1e-72
CCDS6038.1 TNFRSF10D gene_id:8793|Hs108|chr8 ( 386) 1088 198.2 1.2e-50
CCDS6039.1 TNFRSF10A gene_id:8797|Hs108|chr8 ( 468) 706 132.3 9.7e-31
CCDS6037.1 TNFRSF10C gene_id:8794|Hs108|chr8 ( 259) 599 113.7 2.3e-25
>>CCDS6035.1 TNFRSF10B gene_id:8795|Hs108|chr8 (440 aa)
initn: 2988 init1: 2988 opt: 2988 Z-score: 2793.6 bits: 526.1 E(32554): 2.8e-149
Smith-Waterman score: 2988; 99.5% identity (99.8% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTLVLVVAAVLLLVSAESALITQQD
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
CCDS60 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
370 380 390 400 410 420
430 440
pF1KB5 HLLSSGKFMYLEGNADSAMS
::::::::::::::::::::
CCDS60 HLLSSGKFMYLEGNADSAMS
430 440
>>CCDS6036.1 TNFRSF10B gene_id:8795|Hs108|chr8 (411 aa)
initn: 1503 init1: 1503 opt: 1504 Z-score: 1410.2 bits: 270.0 E(32554): 3.1e-72
Smith-Waterman score: 2734; 93.2% identity (93.2% similar) in 440 aa overlap (1-440:1-411)
10 20 30 40 50 60
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTLVLVVAAVLLLVSAESALITQQD
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
CCDS60 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
:::: :::::::::::::::::::::::::::
CCDS60 KESG-----------------------------IIIGVTVAAVVLIVAVFVCKSLLWKKV
190 200 210
250 260 270 280 290 300
pF1KB5 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
340 350 360 370 380 390
430 440
pF1KB5 HLLSSGKFMYLEGNADSAMS
::::::::::::::::::::
CCDS60 HLLSSGKFMYLEGNADSAMS
400 410
>>CCDS6038.1 TNFRSF10D gene_id:8793|Hs108|chr8 (386 aa)
initn: 1029 init1: 584 opt: 1088 Z-score: 1022.7 bits: 198.2 E(32554): 1.2e-50
Smith-Waterman score: 1088; 53.2% identity (71.2% similar) in 344 aa overlap (5-336:5-342)
10 20 30 40 50
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTL--VLVVAAVLLLVSAESALITQ
::..:.::.:: . :: : : :.:: : :: : :. ..:::: : ..:: : .
CCDS60 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 QDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTR
:: .::: .::::.: : .: :: : : :: : : : ::. :.: :: ::
CCDS60 QDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 CDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIEC
: ::... : :::::.::::::.:.:....:::::: ::::::::::::..::: :::.:
CCDS60 CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 VHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWK
..::... .:..::.:::::. : ::: ::: : : ....:. : :. :
CCDS60 -KNESAASSTGKTPAAEETVTTILGMLASPYHYL-IIIVVLVIILAVVVVGFSCR----K
190 200 210 220 230
240 250 260 270 280
pF1KB5 KVLPYLKGICSGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQE
: . ::::::::::: :::: : :. ::::::. :: .: :::::: :::
CCDS60 KFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 MEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADL
.. :: :: :::.. : : ..::: :::: ::::::::.:..: ..
CCDS60 IQGQELAELTGVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLE
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 VPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALET
CCDS60 EGHAKETIQDQLVGSEKLFYEEDEAGSATSCL
360 370 380
>>CCDS6039.1 TNFRSF10A gene_id:8797|Hs108|chr8 (468 aa)
initn: 1387 init1: 645 opt: 706 Z-score: 665.4 bits: 132.3 E(32554): 9.7e-31
Smith-Waterman score: 1343; 52.6% identity (68.0% similar) in 447 aa overlap (5-440:60-466)
10 20 30
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRV
::..:.: :: ..:::: :: : : :::
CCDS60 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB5 PKTLVLVVAAVLL-LVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRD
::. .::..::: .: . .: : .: : . :: . :: ::::: : ::
CCDS60 HKTFKFVVVGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHPGA
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB5 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMC
: : : :.. :.:. :: :: : : : : :::::::::.:::. ::::...: :::
CCDS60 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMC
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB5 RKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSG
::: ::::::::: ::::::::::::::::. :.
CCDS60 RKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHN-----------------------IW
210 220 230 240
220 230 240 250 260
pF1KB5 IIIGVTVAAVVLIVAVF-VCKSLLWKKVLPYLKGICSGGGGDPERVDRSS-------QRP
.:. ::... .:.:::. :: : :: ::::. .:: . :
CCDS60 VILVVTLVVPLLLVAVLIVCCC------------IGSGCGGDPKCMDRVCFWRLGLLRGP
250 260 270 280
270 280 290 300 310 320
pF1KB5 GAEDNVLNEIVSILQP--TQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRR
:::::. :::.: . : : ::.:: ::::. :::.. ::::.. :: ::::: ::::
CCDS60 GAEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRR
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB5 RLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLY
::::::: .:::::: :: ::..::::::. :::.: : ::: :..: .:: :.::
CCDS60 RLLVPANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALY
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB5 TMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS
.::.::::::::.::.:::::::: . :: :..::.: :..::::.::: .. ::.:
CCDS60 AMLMKWVNKTGRNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE
410 420 430 440 450 460
>>CCDS6037.1 TNFRSF10C gene_id:8794|Hs108|chr8 (259 aa)
initn: 689 init1: 403 opt: 599 Z-score: 569.0 bits: 113.7 E(32554): 2.3e-25
Smith-Waterman score: 599; 52.3% identity (72.7% similar) in 176 aa overlap (33-206:3-176)
10 20 30 40 50 60
pF1KB5 QRGQNAPAASGARKRHGPGPREARGARPGLRVPKTL--VLVVAAVLLLVSAESALITQQD
:.:::: :.:..:::: : : :: ..:.
CCDS60 MARIPKTLKFVVVIVAVLLPVLAYSATTARQE
10 20 30
70 80 90 100 110 120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
.::: .::::.: : . :: : : :: : : : ::.. :. :. :: :
CCDS60 EVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
: . . : :: ::.:::::.:::::.:.:::::::: . :: : :.:..:: :.::.::
CCDS60 SDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKC-SRCPSGEVQVSNCTSWDDIQCV-
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
.: :.. . :.::.:::...::::::
CCDS60 EEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAE
160 170 180 190 200 210
440 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:48:49 2016 done: Thu Nov 3 17:48:50 2016
Total Scan time: 3.270 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]