Result of FASTA (omim) for
pF1KB5639
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5639, 440 aa
1>>>pF1KB5639 440 - 440 aa - 440 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9079+/-0.000303; mu= 16.5284+/- 0.019
mean_var=116.9296+/-23.472, 0's: 0 Z-trim(120.5): 76 B-trim: 1173 in 2/56
Lambda= 0.118607
statistics sampled from 35764 (35864) to 35764 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.42), width: 16
Scan time: 10.290
The best scores are: opt bits E(85289)
NP_003833 (OMIM: 275355,603612) tumor necrosis fac ( 440) 2988 522.0 1.2e-147
XP_016869433 (OMIM: 275355,603612) PREDICTED: tumo ( 375) 2450 429.8 5.7e-120
NP_671716 (OMIM: 275355,603612) tumor necrosis fac ( 411) 1504 268.0 3.3e-71
NP_003831 (OMIM: 603614) tumor necrosis factor rec ( 386) 1088 196.8 8.4e-50
NP_003835 (OMIM: 603611) tumor necrosis factor rec ( 468) 706 131.5 4.6e-30
NP_003832 (OMIM: 603613) tumor necrosis factor rec ( 259) 599 112.9 9.8e-25
XP_005253745 (OMIM: 600979) PREDICTED: tumor necro ( 399) 253 53.9 8.8e-07
NP_690610 (OMIM: 134637,601859) tumor necrosis fac ( 314) 249 53.1 1.2e-06
XP_011538067 (OMIM: 134637,601859) PREDICTED: tumo ( 368) 249 53.2 1.3e-06
NP_001307548 (OMIM: 134637,601859) tumor necrosis ( 197) 243 51.9 1.8e-06
NP_690611 (OMIM: 134637,601859) tumor necrosis fac ( 220) 243 51.9 1.9e-06
NP_000034 (OMIM: 134637,601859) tumor necrosis fac ( 335) 243 52.1 2.6e-06
XP_011538069 (OMIM: 134637,601859) PREDICTED: tumo ( 350) 243 52.1 2.6e-06
XP_011538068 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 243 52.2 2.7e-06
XP_006717882 (OMIM: 134637,601859) PREDICTED: tumo ( 362) 243 52.2 2.7e-06
XP_011538066 (OMIM: 134637,601859) PREDICTED: tumo ( 389) 243 52.2 2.8e-06
XP_006719046 (OMIM: 600979) PREDICTED: tumor necro ( 255) 235 50.6 5.5e-06
NP_001257916 (OMIM: 600979) tumor necrosis factor ( 416) 235 50.9 7.7e-06
NP_002333 (OMIM: 600979) tumor necrosis factor rec ( 435) 235 50.9 7.9e-06
XP_016857702 (OMIM: 191191) PREDICTED: tumor necro ( 440) 202 45.2 0.0004
XP_016857701 (OMIM: 191191) PREDICTED: tumor necro ( 440) 202 45.2 0.0004
NP_001057 (OMIM: 191191) tumor necrosis factor rec ( 461) 202 45.2 0.00041
XP_011540365 (OMIM: 191191) PREDICTED: tumor necro ( 462) 202 45.2 0.00041
XP_011540362 (OMIM: 191191) PREDICTED: tumor necro ( 484) 202 45.3 0.00043
XP_016857700 (OMIM: 191191) PREDICTED: tumor necro ( 491) 202 45.3 0.00043
NP_001056 (OMIM: 142680,191190,614810) tumor necro ( 455) 201 45.1 0.00046
NP_001284534 (OMIM: 602746) tumor necrosis factor ( 184) 191 43.0 0.0008
XP_006711082 (OMIM: 602746) PREDICTED: tumor necro ( 197) 191 43.0 0.00084
NP_003811 (OMIM: 602746) tumor necrosis factor rec ( 283) 191 43.2 0.0011
NP_003781 (OMIM: 603366) tumor necrosis factor rec ( 417) 184 42.1 0.0033
NP_003318 (OMIM: 600315,615593) tumor necrosis fac ( 277) 177 40.8 0.0056
XP_016857721 (OMIM: 600315,615593) PREDICTED: tumo ( 277) 177 40.8 0.0056
XP_011540377 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 177 40.8 0.006
XP_016857720 (OMIM: 600315,615593) PREDICTED: tumo ( 303) 177 40.8 0.006
NP_683866 (OMIM: 603366) tumor necrosis factor rec ( 426) 179 41.3 0.006
XP_011540743 (OMIM: 153243) PREDICTED: tumor necro ( 594) 177 41.1 0.0096
NP_001234 (OMIM: 153243) tumor necrosis factor rec ( 595) 177 41.1 0.0096
>>NP_003833 (OMIM: 275355,603612) tumor necrosis factor (440 aa)
initn: 2988 init1: 2988 opt: 2988 Z-score: 2771.5 bits: 522.0 E(85289): 1.2e-147
Smith-Waterman score: 2988; 99.5% identity (99.8% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTLVLVVAAVLLLVSAESALITQQD
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_003 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
370 380 390 400 410 420
430 440
pF1KB5 HLLSSGKFMYLEGNADSAMS
::::::::::::::::::::
NP_003 HLLSSGKFMYLEGNADSAMS
430 440
>>XP_016869433 (OMIM: 275355,603612) PREDICTED: tumor ne (375 aa)
initn: 2450 init1: 2450 opt: 2450 Z-score: 2274.8 bits: 429.8 E(85289): 5.7e-120
Smith-Waterman score: 2450; 99.7% identity (100.0% similar) in 357 aa overlap (84-440:19-375)
60 70 80 90 100 110
pF1KB5 ALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFC
::::::::::::::::::::::::::::::
XP_016 MDDVWGMRTIEAPNSTAQGHHISEDGRDCISCKYGQDYSTHWNDLLFC
10 20 30 40
120 130 140 150 160 170
pF1KB5 LRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPW
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB5 SDIECVHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCK
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 SDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCK
110 120 130 140 150 160
240 250 260 270 280 290
pF1KB5 SLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQE
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 PAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDS
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 WEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERL
290 300 310 320 330 340
420 430 440
pF1KB5 AKQKIEDHLLSSGKFMYLEGNADSAMS
:::::::::::::::::::::::::::
XP_016 AKQKIEDHLLSSGKFMYLEGNADSAMS
350 360 370
>>NP_671716 (OMIM: 275355,603612) tumor necrosis factor (411 aa)
initn: 1503 init1: 1503 opt: 1504 Z-score: 1399.5 bits: 268.0 E(85289): 3.3e-71
Smith-Waterman score: 2734; 93.2% identity (93.2% similar) in 440 aa overlap (1-440:1-411)
10 20 30 40 50 60
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTLVLVVAAVLLLVSAESALITQQD
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_671 MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
:::: :::::::::::::::::::::::::::
NP_671 KESG-----------------------------IIIGVTVAAVVLIVAVFVCKSLLWKKV
190 200 210
250 260 270 280 290 300
pF1KB5 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_671 LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
340 350 360 370 380 390
430 440
pF1KB5 HLLSSGKFMYLEGNADSAMS
::::::::::::::::::::
NP_671 HLLSSGKFMYLEGNADSAMS
400 410
>>NP_003831 (OMIM: 603614) tumor necrosis factor recepto (386 aa)
initn: 1029 init1: 584 opt: 1088 Z-score: 1015.1 bits: 196.8 E(85289): 8.4e-50
Smith-Waterman score: 1088; 53.2% identity (71.2% similar) in 344 aa overlap (5-336:5-342)
10 20 30 40 50
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTL--VLVVAAVLLLVSAESALITQ
::..:.::.:: . :: : : :.:: : :: : :. ..:::: : ..:: : .
NP_003 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 QDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTR
:: .::: .::::.: : .: :: : : :: : : : ::. :.: :: ::
NP_003 QDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 CDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIEC
: ::... : :::::.::::::.:.:....:::::: ::::::::::::..::: :::.:
NP_003 CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 VHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWK
..::... .:..::.:::::. : ::: ::: : : ....:. : :. :
NP_003 -KNESAASSTGKTPAAEETVTTILGMLASPYHYL-IIIVVLVIILAVVVVGFSCR----K
190 200 210 220 230
240 250 260 270 280
pF1KB5 KVLPYLKGICSGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQE
: . ::::::::::: :::: : :. ::::::. :: .: :::::: :::
NP_003 KFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 MEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADL
.. :: :: :::.. : : ..::: :::: ::::::::.:..: ..
NP_003 IQGQELAELTGVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLE
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 VPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALET
NP_003 EGHAKETIQDQLVGSEKLFYEEDEAGSATSCL
360 370 380
>>NP_003835 (OMIM: 603611) tumor necrosis factor recepto (468 aa)
initn: 1387 init1: 645 opt: 706 Z-score: 660.8 bits: 131.5 E(85289): 4.6e-30
Smith-Waterman score: 1343; 52.6% identity (68.0% similar) in 447 aa overlap (5-440:60-466)
10 20 30
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRV
::..:.: :: ..:::: :: : : :::
NP_003 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB5 PKTLVLVVAAVLL-LVSAESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRD
::. .::..::: .: . .: : .: : . :: . :: ::::: : ::
NP_003 HKTFKFVVVGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHPGA
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB5 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMC
: : : :.. :.:. :: :: : : : : :::::::::.:::. ::::...: :::
NP_003 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAEMC
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB5 RKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSG
::: ::::::::: ::::::::::::::::. :.
NP_003 RKCSRGCPRGMVKVKDCTPWSDIECVHKESGNGHN-----------------------IW
210 220 230 240
220 230 240 250 260
pF1KB5 IIIGVTVAAVVLIVAVF-VCKSLLWKKVLPYLKGICSGGGGDPERVDRSS-------QRP
.:. ::... .:.:::. :: : :: ::::. .:: . :
NP_003 VILVVTLVVPLLLVAVLIVCCC------------IGSGCGGDPKCMDRVCFWRLGLLRGP
250 260 270 280
270 280 290 300 310 320
pF1KB5 GAEDNVLNEIVSILQP--TQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRR
:::::. :::.: . : : ::.:: ::::. :::.. ::::.. :: ::::: ::::
NP_003 GAEDNAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRR
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB5 RLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLY
::::::: .:::::: :: ::..::::::. :::.: : ::: :..: .:: :.::
NP_003 RLLVPANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALY
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB5 TMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIEDHLLSSGKFMYLEGNADSAMS
.::.::::::::.::.:::::::: . :: :..::.: :..::::.::: .. ::.:
NP_003 AMLMKWVNKTGRNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE
410 420 430 440 450 460
>>NP_003832 (OMIM: 603613) tumor necrosis factor recepto (259 aa)
initn: 695 init1: 403 opt: 599 Z-score: 565.1 bits: 112.9 E(85289): 9.8e-25
Smith-Waterman score: 599; 52.3% identity (72.7% similar) in 176 aa overlap (33-206:3-176)
10 20 30 40 50 60
pF1KB5 QRGQNAPAASGARKRHGPGPREARGARPGLRVPKTL--VLVVAAVLLLVSAESALITQQD
:.:::: :.:..:::: : : :: ..:.
NP_003 MARIPKTLKFVVVIVAVLLPVLAYSATTARQE
10 20 30
70 80 90 100 110 120
pF1KB5 LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
.::: .::::.: : . :: : : :: : : : ::.. :. :. :: :
NP_003 EVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
: . . : :: ::.:::::.:::::.:.:::::::: . :: : :.:..:: :.::.::
NP_003 SDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKC-SRCPSGEVQVSNCTSWDDIQCV-
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 KESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
.: :.. . :.::.:::...::::::
NP_003 EEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAE
160 170 180 190 200 210
>>XP_005253745 (OMIM: 600979) PREDICTED: tumor necrosis (399 aa)
initn: 137 init1: 79 opt: 253 Z-score: 242.7 bits: 53.9 E(85289): 8.8e-07
Smith-Waterman score: 253; 29.2% identity (50.6% similar) in 257 aa overlap (81-316:62-301)
60 70 80 90 100
pF1KB5 AESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDG---RD--CISCKYGQDYST
:::: ..: :: : .: .. :.
XP_005 AVPPYASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENS-YNE
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 HWNDLLFCLRCTRCDS--GEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRG
::: : .: : :: : :..:::. :.: :.:. : : . : : .:.
XP_005 HWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALE-CTHCEL-----
100 110 120 130 140
170 180 190 200 210
pF1KB5 MVKVGDCTPWSDIECVHKESGTKHSGEAP--AVEETVTSSPGT---PASPCSLSGIIIGV
..:: : .. : .. : : .. .: : . ::::.. : . : .:..
XP_005 ---LSDCPPGTEAE-LKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLV---
150 160 170 180 190
220 230 240 250 260 270
pF1KB5 TVAAVVLIVAVFVCKSLLWKKVLPYLKGIC---SGGGGDPERVDRSSQRPGAEDNVLNEI
:: . .::. : . . : ..: : :. : : . : :. . ..
XP_005 -EAAPGTAQSDTTCKNPL-EPLPPEMSGSLLKRRPQGEGPNPVAGSWEPPKAHP-YFPDL
200 210 220 230 240 250
280 290 300 310 320
pF1KB5 VSILQPTQVPEQEMEVQEPAEPT---GV-NMLSPGE--SEHLLEPAEAERSQRRRLLVPA
:. : : . . . . :: :. :: .. :: . : :::.:
XP_005 VQPLLPISGDVSPVSTGLPAAPVLEAGVPQQQSPLDLTREPQLEPGEQSQVAHGTNGIHV
260 270 280 290 300 310
330 340 350 360 370 380
pF1KB5 NEGDPTETLRQCFDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKW
XP_005 TGGSMTITGNIYIYNGPVLGGPPGPGDLPATPEPPYPIPEEGDPGPPGLSTPHQEDGKAW
320 330 340 350 360 370
>>NP_690610 (OMIM: 134637,601859) tumor necrosis factor (314 aa)
initn: 154 init1: 95 opt: 249 Z-score: 240.3 bits: 53.1 E(85289): 1.2e-06
Smith-Waterman score: 254; 32.6% identity (54.9% similar) in 175 aa overlap (81-234:63-231)
60 70 80 90 100
pF1KB5 AESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHH------ISEDGRDCISCKYGQDYS
::::.. .. : ::. :. :..:.
NP_690 KGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYT
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 THWNDLLFCLRCTRCDSG---EVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCP
. . : :: :: : :::.. :: :.:: :.:. . : . : : : : :
NP_690 DKAHFSSKCRRCRLCDEGHGLEVEIN-CTRTQNTKCRCKPNFFCNSTVCEHCDPC-TKCE
100 110 120 130 140 150
170 180 190 200 210
pF1KB5 RGMVKVGDCTPWSDIECVH-------KESGTKHSGEAPAVEETVTSSPGTPA---SPCSL
.:..: .:: :. .: . ... :: : . .:. : .: : : : .:
NP_690 HGIIK--ECTLTSNTKCKEEVKRKEVQKTCRKHRKENQGSHESPTLNPETVAINLSDVDL
160 170 180 190 200
220 230 240 250 260
pF1KB5 SGIIIGVTVAAVVLIVAV--FVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAED
: : .:.:.:. . : :: :.
NP_690 SKYI--TTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQLLRNWHQLHGK
210 220 230 240 250 260
>>XP_011538067 (OMIM: 134637,601859) PREDICTED: tumor ne (368 aa)
initn: 154 init1: 95 opt: 249 Z-score: 239.5 bits: 53.2 E(85289): 1.3e-06
Smith-Waterman score: 265; 28.5% identity (53.0% similar) in 249 aa overlap (18-234:43-285)
10 20 30 40
pF1KB5 MEQRGQNAPAASGARKRHGPGPREARGARPGLRVPKTLVLVVAAVLL
:: . :.. .: .: ::...... :
XP_011 HVSFPERGINITWELMLRVCAQGWHAQGLPHGTNSLLKGGTETSLSTPTRLVVLTSVARL
20 30 40 50 60 70
50 60 70 80 90
pF1KB5 LVSAESALITQQDLAPQQ-RAAPQQKRSSPSEGL----------CPPGHH------ISED
.. .: .:. . . : . ... ::: ::::.. .. :
XP_011 SSKSVNAQVTDINSKGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGD
80 90 100 110 120 130
100 110 120 130 140
pF1KB5 GRDCISCKYGQDYSTHWNDLLFCLRCTRCDSG---EVELSPCTTTRNTVCQCEEGTFREE
::. :. :..:. . . : :: :: : :::.. :: :.:: :.:. . : .
XP_011 EPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEVEIN-CTRTQNTKCRCKPNFFCNS
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB5 DSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH-------KESGTKHSGEAPAVEETVTS
: : : : : .:..: .:: :. .: . ... :: : . .:. :
XP_011 TVCEHCDPC-TKCEHGIIK--ECTLTSNTKCKEEVKRKEVQKTCRKHRKENQGSHESPTL
200 210 220 230 240
210 220 230 240 250
pF1KB5 SPGTPA---SPCSLSGIIIGVTVAAVVLIVAV--FVCKSLLWKKVLPYLKGICSGGGGDP
.: : : : .:: : .:.:.:. . : :: :.
XP_011 NPETVAINLSDVDLSKYI--TTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQ
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB5 ERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGVNMLSPGESEHLLEPA
XP_011 KVQLLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQS
310 320 330 340 350 360
>>NP_001307548 (OMIM: 134637,601859) tumor necrosis fact (197 aa)
initn: 215 init1: 95 opt: 243 Z-score: 237.3 bits: 51.9 E(85289): 1.8e-06
Smith-Waterman score: 243; 35.7% identity (58.3% similar) in 115 aa overlap (81-186:63-171)
60 70 80 90 100
pF1KB5 AESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHH------ISEDGRDCISCKYGQDYS
::::.. .. : ::. :. :..:.
NP_001 KGLELRKTVTTVETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYT
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB5 THWNDLLFCLRCTRCDSG---EVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCP
. . : :: :: : :::.. :: :.:: :.:. . : . : : : : :
NP_001 DKAHFSSKCRRCRLCDEGHGLEVEIN-CTRTQNTKCRCKPNFFCNSTVCEHCDPC-TKCE
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB5 RGMVKVGDCTPWSDIECVHKESGTKHSGEAPAVEETVTSSPGTPASPCSLSGIIIGVTVA
.:..: .:: :. .: :: :..
NP_001 HGIIK--ECTLTSNTKC--KEEGSRSNLGWLCLLLLPIPLIVWGNSGNKFI
160 170 180 190
440 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:48:50 2016 done: Thu Nov 3 17:48:51 2016
Total Scan time: 10.290 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]