FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5646, 488 aa 1>>>pF1KB5646 488 - 488 aa - 488 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1920+/-0.000304; mu= 5.2997+/- 0.019 mean_var=156.6502+/-31.161, 0's: 0 Z-trim(121.7): 42 B-trim: 0 in 0/61 Lambda= 0.102473 statistics sampled from 38662 (38704) to 38662 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.454), width: 16 Scan time: 10.360 The best scores are: opt bits E(85289) NP_477520 (OMIM: 228600,608041) anthrax toxin rece ( 488) 3260 493.5 5.6e-139 NP_001139266 (OMIM: 228600,608041) anthrax toxin r ( 489) 3176 481.1 3.1e-135 NP_001273709 (OMIM: 228600,608041) anthrax toxin r ( 411) 2728 414.8 2.3e-115 NP_001273710 (OMIM: 228600,608041) anthrax toxin r ( 411) 2728 414.8 2.3e-115 XP_016863200 (OMIM: 228600,608041) PREDICTED: anth ( 412) 2644 402.4 1.3e-111 XP_011529889 (OMIM: 228600,608041) PREDICTED: anth ( 412) 2644 402.4 1.3e-111 NP_115584 (OMIM: 230740,602089,606410) anthrax tox ( 564) 1845 284.3 5.9e-76 NP_444262 (OMIM: 230740,602089,606410) anthrax tox ( 368) 1246 195.7 1.9e-49 NP_060623 (OMIM: 230740,602089,606410) anthrax tox ( 333) 1040 165.2 2.6e-40 XP_016860566 (OMIM: 230740,602089,606410) PREDICTE ( 330) 1035 164.5 4.2e-40 XP_016860565 (OMIM: 230740,602089,606410) PREDICTE ( 336) 1035 164.5 4.3e-40 XP_016860564 (OMIM: 230740,602089,606410) PREDICTE ( 347) 1035 164.5 4.4e-40 >>NP_477520 (OMIM: 228600,608041) anthrax toxin receptor (488 aa) initn: 3260 init1: 3260 opt: 3260 Z-score: 2616.1 bits: 493.5 E(85289): 5.6e-139 Smith-Waterman score: 3260; 99.8% identity (99.8% similar) in 488 aa overlap (1-488:1-488) 10 20 30 40 50 60 pF1KB5 MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_477 MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_477 EIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 HEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_477 HEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_477 FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_477 GRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPPPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: NP_477 KSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_477 KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 ETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEGRCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_477 ETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEGRCI 430 440 450 460 470 480 pF1KB5 NFSRVPSQ :::::::: NP_477 NFSRVPSQ >>NP_001139266 (OMIM: 228600,608041) anthrax toxin recep (489 aa) initn: 3173 init1: 3173 opt: 3176 Z-score: 2548.9 bits: 481.1 E(85289): 3.1e-135 Smith-Waterman score: 3176; 99.4% identity (99.4% similar) in 480 aa overlap (1-480:1-479) 10 20 30 40 50 60 pF1KB5 MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 EIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 HEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 KSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPPPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: NP_001 KSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 ETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEGRCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :: NP_001 ETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDE-VCI 430 440 450 460 470 pF1KB5 NFSRVPSQ NP_001 WECIEKELTA 480 >>NP_001273709 (OMIM: 228600,608041) anthrax toxin recep (411 aa) initn: 2728 init1: 2728 opt: 2728 Z-score: 2192.1 bits: 414.8 E(85289): 2.3e-115 Smith-Waterman score: 2728; 99.8% identity (99.8% similar) in 411 aa overlap (78-488:1-411) 50 60 70 80 90 100 pF1KB5 VLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLE :::::::::::::::::::::::::::::: NP_001 MRLSFIVFSSQATIILPLTGDRGKISKGLE 10 20 30 110 120 130 140 150 160 pF1KB5 DLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISR 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 SLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPS 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 SVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKA 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 GETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKV 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 VIKDPPPPPPPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGAR ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGAR 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 LEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVS 340 350 360 370 380 390 470 480 pF1KB5 LMRPQEGDEGRCINFSRVPSQ ::::::::::::::::::::: NP_001 LMRPQEGDEGRCINFSRVPSQ 400 410 >>NP_001273710 (OMIM: 228600,608041) anthrax toxin recep (411 aa) initn: 2728 init1: 2728 opt: 2728 Z-score: 2192.1 bits: 414.8 E(85289): 2.3e-115 Smith-Waterman score: 2728; 99.8% identity (99.8% similar) in 411 aa overlap (78-488:1-411) 50 60 70 80 90 100 pF1KB5 VLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLE :::::::::::::::::::::::::::::: NP_001 MRLSFIVFSSQATIILPLTGDRGKISKGLE 10 20 30 110 120 130 140 150 160 pF1KB5 DLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISR 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 SLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPS 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 SVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKA 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 GETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKV 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 VIKDPPPPPPPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGAR ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGAR 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 LEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVS 340 350 360 370 380 390 470 480 pF1KB5 LMRPQEGDEGRCINFSRVPSQ ::::::::::::::::::::: NP_001 LMRPQEGDEGRCINFSRVPSQ 400 410 >>XP_016863200 (OMIM: 228600,608041) PREDICTED: anthrax (412 aa) initn: 2641 init1: 2641 opt: 2644 Z-score: 2125.0 bits: 402.4 E(85289): 1.3e-111 Smith-Waterman score: 2644; 99.3% identity (99.3% similar) in 403 aa overlap (78-480:1-402) 50 60 70 80 90 100 pF1KB5 VLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLE :::::::::::::::::::::::::::::: XP_016 MRLSFIVFSSQATIILPLTGDRGKISKGLE 10 20 30 110 120 130 140 150 160 pF1KB5 DLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISR 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 SLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPS 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 SVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKA 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 GETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKV 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 VIKDPPPPPPPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGAR ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGAR 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 LEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVS 340 350 360 370 380 390 470 480 pF1KB5 LMRPQEGDEGRCINFSRVPSQ ::::::::: :: XP_016 LMRPQEGDE-VCIWECIEKELTA 400 410 >>XP_011529889 (OMIM: 228600,608041) PREDICTED: anthrax (412 aa) initn: 2641 init1: 2641 opt: 2644 Z-score: 2125.0 bits: 402.4 E(85289): 1.3e-111 Smith-Waterman score: 2644; 99.3% identity (99.3% similar) in 403 aa overlap (78-480:1-402) 50 60 70 80 90 100 pF1KB5 VLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLE :::::::::::::::::::::::::::::: XP_011 MRLSFIVFSSQATIILPLTGDRGKISKGLE 10 20 30 110 120 130 140 150 160 pF1KB5 DLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISR 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB5 SLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPS 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB5 SVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKA 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 GETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKV 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB5 VIKDPPPPPPPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGAR ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGAR 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB5 LEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVS 340 350 360 370 380 390 470 480 pF1KB5 LMRPQEGDEGRCINFSRVPSQ ::::::::: :: XP_011 LMRPQEGDE-VCIWECIEKELTA 400 410 >>NP_115584 (OMIM: 230740,602089,606410) anthrax toxin r (564 aa) initn: 1817 init1: 1437 opt: 1845 Z-score: 1484.6 bits: 284.3 E(85289): 5.9e-76 Smith-Waterman score: 1845; 56.1% identity (78.4% similar) in 485 aa overlap (3-485:4-487) 10 20 30 40 50 pF1KB5 MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNW ::: .:: . .:. .: :: : . :.: .:::::.::::::: ..: NP_115 MATAERRALGIGFQWLSLATLVLICAGQGGR-REDGGPACYGGFDLYFILDKSGSVLHHW 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 IEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETY ::: ::.:::..:.::..:.::::::...: .. :: :: .: .:::.:..: : :.:: NP_115 NEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 IHEGLKLANEQI--QKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVG .:::.. :.::: .. : .:.:.:::::::.: . :.:.::. ::.::: ::::: NP_115 MHEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQI : ::...:: ::::::..::::. :::::.:::.::: .:: ::: .::..:.:: ::. NP_115 VKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 VLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSF :. : :: . :::.. .:.. : . :: ::. . .:::::::...: ..::. NP_115 VVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSM 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 NGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPP : : : ::.:.:.:.:.::.: :..:.:.:::...:.:::::::: :.::. :::: NP_115 NDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 PAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVK .::... :: :::::::::::::::::::::::::::.::::::::.::::::: :: NP_115 EESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVK 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB5 IPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEG .::. : .:: . . :::.::::.:::::.:::. :::::.:::: :: : NP_115 MPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTG 420 430 440 450 460 470 480 pF1KB5 RCINFSRVPSQ :::::.:: NP_115 RCINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPST 480 490 500 510 520 530 >>NP_444262 (OMIM: 230740,602089,606410) anthrax toxin r (368 aa) initn: 1383 init1: 813 opt: 1246 Z-score: 1008.8 bits: 195.7 E(85289): 1.9e-49 Smith-Waterman score: 1246; 51.6% identity (76.5% similar) in 366 aa overlap (3-366:4-364) 10 20 30 40 50 pF1KB5 MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNW ::: .:: . .:. .: :: : . :.: .:::::.::::::: ..: NP_444 MATAERRALGIGFQWLSLATLVLICAGQGGR-REDGGPACYGGFDLYFILDKSGSVLHHW 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 IEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETY ::: ::.:::..:.::..:.::::::...: .. :: :: .: .:::.:..: : :.:: NP_444 NEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 IHEGLKLANEQI--QKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVG .:::.. :.::: .. : .:.:.:::::::.: . :.:.::. ::.::: ::::: NP_444 MHEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQI : ::...:: ::::::..::::. :::::.:::.::: .:: ::: .::..:.:: ::. NP_444 VKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 VLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSF :. : :: . :::.. .:.. : . :: ::. . .:::::::...: ..::. NP_444 VVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSM 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 NGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPP : : : ::.:.:.:.:.::.: :..:.:.:::...:.:::::::: :.::. :::: NP_444 NDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPP- 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 PAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVK :: :: NP_444 ---AEESEENKIK 360 >>NP_060623 (OMIM: 230740,602089,606410) anthrax toxin r (333 aa) initn: 1042 init1: 632 opt: 1040 Z-score: 844.8 bits: 165.2 E(85289): 2.6e-40 Smith-Waterman score: 1040; 51.3% identity (76.6% similar) in 316 aa overlap (3-316:4-318) 10 20 30 40 50 pF1KB5 MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNW ::: .:: . .:. .: :: : . :.: .:::::.::::::: ..: NP_060 MATAERRALGIGFQWLSLATLVLICAGQGGR-REDGGPACYGGFDLYFILDKSGSVLHHW 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 IEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETY ::: ::.:::..:.::..:.::::::...: .. :: :: .: .:::.:..: : :.:: NP_060 NEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 IHEGLKLANEQI--QKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVG .:::.. :.::: .. : .:.:.:::::::.: . :.:.::. ::.::: ::::: NP_060 MHEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQI : ::...:: ::::::..::::. :::::.:::.::: .:: ::: .::..:.:: ::. NP_060 VKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 VLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSF :. : :: . :::.. .:.. : . :: ::. . .:::::::...: ..::. NP_060 VVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSM 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 NGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPP : : : ::.:.:.:.:.:: NP_060 NDGLSFISSSVIITTTHCSLHKIASGPTTAACME 300 310 320 330 >>XP_016860566 (OMIM: 230740,602089,606410) PREDICTED: a (330 aa) initn: 1038 init1: 602 opt: 1035 Z-score: 840.9 bits: 164.5 E(85289): 4.2e-40 Smith-Waterman score: 1035; 51.1% identity (76.5% similar) in 315 aa overlap (3-315:4-317) 10 20 30 40 50 pF1KB5 MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNW ::: .:: . .:. .: :: : . :.: .:::::.::::::: ..: XP_016 MATAERRALGIGFQWLSLATLVLICAGQGGR-REDGGPACYGGFDLYFILDKSGSVLHHW 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 IEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETY ::: ::.:::..:.::..:.::::::...: .. :: :: .: .:::.:..: : :.:: XP_016 NEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 IHEGLKLANEQI--QKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVG .:::.. :.::: .. : .:.:.:::::::.: . :.:.::. ::.::: ::::: XP_016 MHEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQI : ::...:: ::::::..::::. :::::.:::.::: .:: ::: .::..:.:: ::. XP_016 VKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 VLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSF :. : :: . :::.. .:.. : . :: ::. . .:::::::...: ..::. XP_016 VVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSM 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 NGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPP : : : ::.:.:.:.:.: XP_016 NDGLSFISSSVIITTTHCGLSLEQSEVDIVP 300 310 320 330 488 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:09:44 2016 done: Sat Nov 5 13:09:45 2016 Total Scan time: 10.360 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]